Role of DOCK8 in TLR9 signaling in B lymphocytes

DOCK8: dedicator of cytokinesis 8; TLR9: toll-like receptor 9; MyD88: myeloid differentiation primary response protein 88; Pyk2: proline-rich tyrosine kinase 2; Lyn: a member of the Src family of protein tyrosine kinases, expressed in hematopoietic cells; Syk: spleen-associated tyrosine kinase; STAT3: signal transducer and activator of transcription 3.