Tissue PCR sequencing | Tissue allele specific PCR sequencing | Tissue FISH | Tissue IHC | Tissue NGS | ctDNA PCR | ctDNA NGS | Tissue RNA | |
EGFR (sensitizing and T790M) | + | ++ | 0 | 0 | ++ | + | + | + |
HER2 mutation | + | ++ | 0 | 0 | ++ | + | + | + |
METex14 mutation | 0 | ++ | 0 | 0 | ++ | + | + | ++ |
BRAF mutation | + | ++ | 0 | 0 | ++ | + | + | + |
KRAS mutation | + | ++ | 0 | 0 | ++ | + | + | + |
ALK rearrangement | 0 | 0 | ++ | ++ | + | + | + | ++ |
ROS1 rearrangement | 0 | 0 | ++ | 0 | + | 0 | + | ++ |
MET amplification | 0 | 0 | ++ | 0 | + | 0 | + | + |
RET rearrangement | 0 | 0 | ++ | 0 | + | + | + | ++ |
PD-L1 protein expression | 0 | 0 | 0 | ++ | 0 | 0 | 0 | 0 |
NTRK fusion | 0 | 0 | ++ | + | + | 0 | + | ++ |
NRG1 fusion | 0 | 0 | ++ | + | + | 0 | + | ++ |
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