Primary tumor (T) | |||
T category | T criteria | ||
TX | Primary tumor cannot be assessed | ||
T0 | No evidence of primary tumor | ||
T1* | Invades lamina propria or submucosa and less than or equal to 1 cm in size | ||
T2* | Invades muscularis propria or greater than 1 cm in size | ||
T3* | Invades through the muscularis propria into subserosal tissue without penetration of overlying serosa | ||
T4* | Invades visceral peritoneum (serosal) or other organs or adjacent structures | ||
* NOTE: For any T, add (m) for multiple tumors [TX(#) or TX(m), where X = 1 to 4 and # = number of primary tumors identified¶]; for multiple tumors with different Ts, use the highest. ¶ Example: If there are two primary tumors, one of which penetrates only the subserosa, we define the primary tumor as either T3(2) or T3(m). | |||
Regional lymph nodes (N) | |||
N category | N criteria | ||
NX | Regional lymph nodes cannot be assessed | ||
N0 | No regional lymph node metastasis | ||
N1 | Regional lymph node metastsis | ||
Distant metastasis (M) | |||
M category | M criteria | ||
M0 | No distant metastasis | ||
M1 | Distant metastasis | ||
M1a | Metastasis confined to liver | ||
M1b | Metastases in at least one extrahepatic site (eg, lung, ovary, nonregional lymph node, peritoneum, bone) | ||
M1c | Both hepatic and extrahepatic metastases | ||
Prognostic stage groups | |||
When T is... | And N is... | And M is... | Then the stage group is... |
TX, T0 | NX, N0, N1 | M1 | IV |
T1 | N0 | M0 | I |
T1 | N1 | M0 | III |
T1 | NX, N0, N1 | M1 | IV |
T2 | N0 | M0 | II |
T2 | N1 | M0 | III |
T2 | NX, N0, N1 | M1 | IV |
T3 | N0 | M0 | II |
T3 | N1 | M0 | III |
T3 | NX, N0, N1 | M1 | IV |
T4 | N0 | M0 | III |
T4 | N1 | M0 | III |
T4 | NX, N0, N1 | M1 | IV |
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