Cellular pleomorphism per se is not a useful feature for grading NETs. The following grading scheme has been proposed for gastrointestinal NETs. | |
Grade | Definition |
GX | Grade cannot be assessed |
G1 | Mitotic count (per 10 HPF)* <2 and Ki-67 index (%)¶ <3 |
G2 | Mitotic count (per 10 HPF) = 2 to 20 or Ki-67 index (%)¶ = 3 to 20 |
G3 | Mitotic count (per 10 HPF) >20 or Ki-67 index (%)¶ >20 |
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