Primary tumor (T) | |||
T category | T criteria | ||
TX | Primary tumor cannot be assessed | ||
T1 | Tumor invades the mucosa or submucosa only and is ≤1 cm (duodenal tumors). Tumor ≤1 cm and confined within the sphincter of Oddi (ampullary tumors). | ||
T2 | Tumor invades the muscularis propria or is >1 cm (duodenal). Tumor invades through sphincter into duodenal submucosa or muscularis propria, or is >1 cm (ampullary). | ||
T3 | Tumor invades the pancreas or peripancreatic adipose tissue | ||
T4 | Tumor invades the visceral peritoneum (serosa) or other organs | ||
NOTE: Multiple tumors should be designated as such (and the largest tumor should be used to assign the T category):
| |||
Regional lymph nodes (N) | |||
N category | N criteria | ||
NX | Regional lymph nodes cannot be assessed | ||
N0 | No regional lymph node involvement | ||
N1 | Regional lymph node involvement | ||
Distant metastasis (M) | |||
M category | M criteria | ||
M0 | No distant metastasis | ||
M1 | Distant metastases | ||
M1a | Metastasis confined to liver | ||
M1b | Metastases in at least one extrahepatic site (eg, lung, ovary, nonregional lymph node, peritoneum, bone) | ||
M1c | Both hepatic and extrahepatic metastases | ||
Prognostic stage groups | |||
When T is... | And N is... | And M is... | Then the stage group is... |
T1 | N0 | M0 | I |
T2 | N0 | M0 | II |
T3 | N0 | M0 | II |
T4 | N0 | M0 | III |
Any T | N1 | M0 | III |
Any T | Any N | M1 | IV |
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