Primary tumor (T) | |||
T category | T criteria | ||
TX | Primary tumor cannot be assessed (eg, curetted) | ||
T0 | No evidence of primary tumor | ||
Tis | In situ primary tumor | ||
T1 | Maximum clinical tumor diameter ≤2 cm | ||
T2 | Maximum clinical tumor diameter >2 but ≤5 cm | ||
T3 | Maximum clinical tumor diameter >5 cm | ||
T4 | Primary tumor invades fascia, muscle, cartilage, or bone | ||
Regional lymph nodes (N) | |||
Clinical (N) | |||
N category | N criteria | ||
NX | Regional lymph nodes cannot be clinically assessed (eg, previously removed for another reason, or because of body habitus) | ||
N0 | No regional lymph node metastasis detected on clinical and/or radiologic examination | ||
N1 | Metastasis in regional lymph node(s) | ||
N2 | In-transit metastasis (discontinuous from primary tumor; located between primary tumor and draining regional nodal basin, or distal to the primary tumor) without lymph node metastasis | ||
N3 | In-transit metastasis (discontinuous from primary tumor; located between primary tumor and draining regional nodal basin, or distal to the primary tumor) with lymph node metastasis | ||
Distant metastasis (M) | |||
Clinical (M) | |||
M category | M criteria | ||
M0 | No distant metastasis detected on clinical and/or radiologic examination | ||
M1 | Distant metastasis detected on clinical and/or radiologic examination | ||
M1a | Metastasis to distant skin, distant subcutaneous tissue, or distant lymph node(s) | ||
M1b | Metastasis to lung | ||
M1c | Metastasis to all other visceral sites | ||
Prognostic stage groups | |||
Clinical stage group (cTNM) | |||
When T is... | And N is... | And M is... | Then the stage group is... |
Tis | N0 | M0 | 0 |
T1 | N0 | M0 | I |
T2-3 | N0 | M0 | IIA |
T4 | N0 | M0 | IIB |
T0-4 | N1-3 | M0 | III |
T0-4 | Any N | M1 | IV |
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