Primary tumor (T) | |||||||
T category | T criteria | ||||||
TX | Primary tumor cannot be assessed | ||||||
T0 | No evidence of primary tumor | ||||||
T1 | Tumor size category 1 | ||||||
T1a | Tumor size category 1 without ciliary body involvement and extraocular extension | ||||||
T1b | Tumor size category 1 with ciliary body involvement | ||||||
T1c | Tumor size category 1 without ciliary body involvement but with extraocular extension ≤5 mm in largest diameter | ||||||
T1d | Tumor size category 1 with ciliary body involvement and extraocular extension ≤5 mm in largest diameter | ||||||
T2 | Tumor size category 2 | ||||||
T2a | Tumor size category 2 without ciliary body involvement and extraocular extension | ||||||
T2b | Tumor size category 2 with ciliary body involvement | ||||||
T2c | Tumor size category 2 without ciliary body involvement but with extraocular extension ≤5 mm in largest diameter | ||||||
T2d | Tumor size category 2 with ciliary body involvement and extraocular extension ≤5 mm in largest diameter | ||||||
T3 | Tumor size category 3 | ||||||
T3a | Tumor size category 3 without ciliary body involvement and extraocular extension | ||||||
T3b | Tumor size category 3 with ciliary body involvement | ||||||
T3c | Tumor size category 3 without ciliary body involvement but with extraocular extension ≤5 mm in largest diameter | ||||||
T3d | Tumor size category 3 with ciliary body involvement and extraocular extension ≤5 mm in largest diameter | ||||||
T4 | Tumor size category 4 | ||||||
T4a | Tumor size category 4 without ciliary body involvement and extraocular extension | ||||||
T4b | Tumor size category 4 with ciliary body involvement | ||||||
T4c | Tumor size category 4 without ciliary body involvement but with extraocular extension ≤5 mm in largest diameter | ||||||
T4d | Tumor size category 4 with ciliary body involvement and extraocular extension ≤5 mm in largest diameter | ||||||
T4e | Any tumor size category with extraocular extension >5 mm in largest diameter | ||||||
NOTES:
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Classification for ciliary body and choroid uveal melanoma based on thickness and diameter | |||||||
Largest basal diameter (mm) | |||||||
Thickness (mm) | ≤3.0 | 3.1 to 6.0 | 6.1 to 9.0 | 9.1 to 12.0 | 12.1 to 15.0 | 15.1 to 18.0 | >18.0 |
>15.0 | 4 | 4 | 4 | ||||
12.1 to 15.0 | 3 | 3 | 4 | 4 | |||
9.1 to 12.0 | 3 | 3 | 3 | 3 | 3 | 4 | |
6.1 to 9.0 | 2 | 2 | 2 | 2 | 3 | 3 | 4 |
3.1 to 6.0 | 1 | 1 | 1 | 2 | 2 | 3 | 4 |
≤3.0 | 1 | 1 | 1 | 1 | 2 | 2 | 4 |
Regional lymph nodes (N) | |||||||
N category | N criteria | ||||||
NX | Regional lymph nodes cannot be assessed | ||||||
N0 | No regional lymph node involvement | ||||||
N1 | Regional lymph node metastases or discrete tumor deposits in the orbit | ||||||
N1a | Metastasis in one or more regional lymph node(s) | ||||||
N1b | No regional lymph nodes are positive, but there are discrete tumor deposits in the orbit that are not contiguous to the eye (choroidal and ciliary body) | ||||||
Distant metastasis (M) | |||||||
M category | M criteria | ||||||
M0 | No distant metastasis by clinical classification | ||||||
M1 | Distant metastasis | ||||||
M1a | Largest diameter of the largest metastasis ≤3.0 cm | ||||||
M1b | Largest diameter of the largest metastasis 3.1-8.0 cm | ||||||
M1c | Largest diameter of the largest metastasis ≥8.1 cm | ||||||
Prognostic stage groups | |||||||
When T is... | And N is... | And M is... | Then the stage group is... | ||||
T1a | N0 | M0 | I | ||||
T1b-d | N0 | M0 | IIA | ||||
T2a | N0 | M0 | IIA | ||||
T2b | N0 | M0 | IIB | ||||
T3a | N0 | M0 | IIB | ||||
T2c-d | N0 | M0 | IIIA | ||||
T3b-c | N0 | M0 | IIIA | ||||
T4a | N0 | M0 | IIIA | ||||
T3d | N0 | M0 | IIIB | ||||
T4b-c | N0 | M0 | IIIB | ||||
T4d-e | N0 | M0 | IIIC | ||||
Any T | N1 | M0 | IV | ||||
Any T | Any N | M1a-c | IV |
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