Primary tumor (T) | |
T category | T criteria |
TX | Primary tumor cannot be assessed |
T0 | No evidence of primary tumor |
T1 | Tumor limited to the iris |
T1a | Tumor limited to the iris, not more than 3 clock hours in size |
T1b | Tumor limited to the iris, more than 3 clock hours in size |
T1c | Tumor limited to the iris with secondary glaucoma |
T2 | Tumor confluent with or extending into the ciliary body, choroid, or both |
T2a | Tumor confluent with or extending into the ciliary body, without secondary glaucoma |
T2b | Tumor confluent with or extending into the ciliary body and choroid, without secondary glaucoma |
T2c | Tumor confluent with or extending into the ciliary body, choroid, or both, with secondary glaucoma |
T3 | Tumor confluent with or extending into the ciliary body, choroid, or both, with scleral extension |
T4 | Tumor with extrascleral extension |
T4a | Tumor with extrascleral extension ≤5 mm in largest diameter |
T4b | Tumor with extrascleral extension >5 mm in largest diameter |
NOTE: Iris melanomas originate from, and are predominately located in, this region of the uvea. If less than half the tumor volume is located within the iris, the tumor may have originated in the ciliary body, and consideration should be given to classifying it accordingly. | |
Regional lymph nodes (N) | |
N category | N criteria |
NX | Regional lymph nodes cannot be assessed |
N0 | No regional lymph node involvement |
N1 | Regional lymph node metastases or discrete tumor deposits in the orbit |
N1a | Metastasis in one or more regional lymph node(s) |
N1b | No regional lymph nodes are positive, but there are discrete tumor deposits in the orbit that are not contiguous to the eye (choroidal and ciliary body) |
Distant metastasis (M) | |
M category | M criteria |
M0 | No distant metastasis by clinical classification |
M1 | Distant metastasis |
M1a | Largest diameter of the largest metastasis ≤3.0 cm |
M1b | Largest diameter of the largest metastasis 3.1-8.0 cm |
M1c | Largest diameter of the largest metastasis ≥8.1 cm |
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