Antibody-mediated rejection | Morphological tissue injury |
Grade I (mild) | Well-preserved architecture with mild interacinar inflammation and rare acinar cell damage |
Grade II (moderate) | Overall preserved architecture with interacinar infiltrates with multi-acinar cell damage/dropout, extravasation of red blood cells, and interacinar capillaritis |
Grade III (severe) | Architectural disarray, interstitial hemorrhage, multifocal parenchymal necrosis, arterial and venous wall necrosis and thrombosis |
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