Clinical (cTNM) | |||
Clinical staging includes microstaging of the primary melanoma and clinical/radiologic/biopsy evaluation for metastases. By convention, clinical staging should be used after biopsy of the primary melanoma, with clinical assessment for regional and distant metastases. Note that pathological assessment of the primary melanoma is used for both clinical and pathological classification. Diagnostic biopsies to evaluate possible regional and/or distant metastasis also are included. Note there is only one stage group for clinical Stage III melanoma. | |||
When T is... | And N is... | And M is... | Then the clinical stage group is... |
Tis | N0 | M0 | 0 |
T1a | N0 | M0 | IA |
T1b | N0 | M0 | IB |
T2a | N0 | M0 | IB |
T2b | N0 | M0 | IIA |
T3a | N0 | M0 | IIA |
T3b | N0 | M0 | IIB |
T4a | N0 | M0 | IIB |
T4b | N0 | M0 | IIC |
Any T, Tis | ≥N1 | M0 | III |
Any T | Any N | M1 | IV |
Pathological (pTNM) | |||
Pathological staging includes microstaging of the primary melanoma, including any additional staging information from the wide-excision (surgical) specimen that constitutes primary tumor surgical treatment and pathological information about the regional lymph nodes after SLN biopsy or therapeutic lymph node dissection for clinically evident regional lymph node disease. | |||
When T is... | And N is... | And M is... | Then the pathological stage group is... |
Tis | N0 | M0 | 0 |
T1a | N0 | M0 | IA |
T1b | N0 | M0 | IA |
T2a | N0 | M0 | IB |
T2b | N0 | M0 | IIA |
T3a | N0 | M0 | IIA |
T3b | N0 | M0 | IIB |
T4a | N0 | M0 | IIB |
T4b | N0 | M0 | IIC |
T0 | N1b, N1c | M0 | IIIB |
T0 | N2b, N2c, N3b, or N3c | M0 | IIIC |
T1a/b-T2a | N1a or N2a | M0 | IIIA |
T1a/b-T2a | N1b/c or N2b | M0 | IIIB |
T2b/T3a | N1a-N2b | M0 | IIIB |
T1a-T3a | N2c or N3a/b/c | M0 | IIIC |
T3b/T4a | Any N ≥N1 | M0 | IIIC |
T4b | N1a-N2c | M0 | IIIC |
T4b | N3a/b/c | M0 | IIID |
Any T, Tis | Any N | M1 | IV |
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