Version October 2024
| Condition | Material "eliminated" through the epidermis | |
| Endogenous substances | Chondrodermatitis nodularis helicis | Altered collagen |
| Perforating pseudoxanthoma elasticum | Elastic fibers | |
| Cutaneous perforating calcinosis | Calcium | |
| Gouty tophi | Sodium urate crystals | |
| Papular mucinosis | Mucin | |
| Granulomas | Exogenous foreign body granuloma | Foreign body material (ie, silica or wood splinters) |
| Perforating granuloma annulare | Necrobiotic material | |
| Necrobiosis lipoidica | Degenerated collagen | |
| Rheumatoid nodule | Fibrinoid necrosis | |
| Infectious diseases | Chromoblastomycosis | Causative organism |
| Leprosy | Causative organism | |
| Schistosomiasis | Causative organism | |
| Tuberculosis | Causative organism | |
| Blastomycosis | Causative organism | |
| Leishmaniasis | Causative organism | |
| Aspergillosis | Causative organism | |
| Tumor cells | Nevus sebaceous | Hair follicles from the undifferentiated cells |
| Pilomatricoma | Calcified shadow cells | |
| Keratoacanthoma | Eosinophilic keratin |
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