Patients with history of TB (current or past) |
- Persistent or progressive clinical and/or radiographic findings while on antituberculous therapy
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- Lack of conversion of cultures to negative during first three months of antituberculous therapy
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- Incomplete adherence to prescribed antituberculous therapy
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- Lack of directly observed therapy or poorly supervised antituberculous therapy
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- Documented treatment failure or relapse
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- History of an inappropriate treatment regimen, including too few effective drugs or inadequate drug dosing
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Patients without prior history of TB |
- Exposure to an individual with known or suspected drug-resistant TB
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- Residence in or travel to a region with high prevalence of drug-resistant TB
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- Residence in or work in an institution or setting with documented drug-resistant TB
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- Among foreign-born individuals: Emigration within the previous two years from a region with known drug-resistant TB
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