Causes of left upper quadrant (LUQ) abdominal pain

LUQ	Clinical features	Comments
Splenomegaly	Pain or discomfort in LUQ, left shoulder pain, and/or early satiety.	Multiple etiologies.
Splenic infarct	Severe LUQ pain.	Atypical presentations common. Associated with a variety of underlying conditions (eg, hypercoagulable state, atrial fibrillation, and splenomegaly).
Splenic abscess	Associated with fever and LUQ tenderness.	Uncommon. May also be associated with splenic infarction.
Splenic rupture	May complain of LUQ, left chest wall, or left shoulder pain that is worse with inspiration.	Most often associated with trauma.

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