(A) Pigmented nodular lesion on the knee of a three-year-old girl.
(B) Histologic image of the lesion showing high mitotic activity, poor cellular maturation, and atypical melanocytes (H&E stain, x20 magnification).
From: Albino FP, Wood BC, Oh A, et al. A case of pediatric melanoma: Treatment considerations in advanced disease. Plast Reconstr Surg Glob Open 2015; 3:e402. DOI:
10.1097/GOX.0000000000000370. Copyright © 2015 American Society of Plastic Surgeons. Reproduced with permission from Wolters Kluwer Health. Unauthorized reproduction of this material is prohibited.