Drug | Mechanism | |
Immune | Non-immune | |
Antibiotics | ||
Rifampin* | ||
Sulfisoxazole | X | |
Trimethoprim-sulfamethoxazole | X | |
Antipsychotics | ||
Quetiapine | X | |
Antiseizure medications | ||
Valproic acid | X | |
Cancer therapies | ||
Bevacizumab | X | |
Bortezomib | X | |
Carfilzomib | X | |
Dasatinib | X | |
Docetaxel | X | |
Gemcitabine | X | X |
Imatinib | X | |
Ixazomib | X | |
Mitomycin | X | |
Oxaliplatin | X | |
Palbociclib | X | |
Pentostatin | X | |
Ponatinib | X | |
Sunitinib | X | |
Drugs of abuse | ||
Cocaine | X | |
Oxymorphone extended release (formulated with PEO, Opana ER) | X | |
Oxycodone (OxyContin formulated with PEO) | X | |
Gene therapy | ||
Onasemnogene abeparvovec* | ||
Hemophilia A | ||
Emicizumab | X | |
Immunosuppressive therapies | ||
Adalimumab | X | |
Cyclosporine | X | |
Everolimus | X | |
Infliximab | X | |
Interferons (type 1, alpha and beta) | X | |
Intravenous immune globulin (IVIG) | X | |
Sirolimus | X | |
Tacrolimus | X | |
Leg cramps, other minor symptoms, malaria (also as a beverage: tonic water, bitter lemon) | ||
Quinine | X |
DITMA: drug-induced thrombotic microangiopathy; HUS: hemolytic uremic syndrome; PEO: polyethylene oxide; TMA: thrombotic microangiopathy; TTP: thrombotic thrombocytopenic purpura.
* For rifampin, supporting evidence is lacking; for rifampin and onasemnogene abeparvovec, the proposed mechanism (immune versus non-immune) is unknown.Do you want to add Medilib to your home screen?