1. Single or (most often) recurrent thunderclap headaches. |
2. Multifocal segmental cerebral artery vasoconstriction demonstrated on cerebral angiography (with CTA, MRA, or DSA) that usually develops within a week of symptom onset. |
3. No evidence for aneurysmal SAH. |
4. Brain imaging findings are often normal, or may show vasogenic edema (PRES) and/or FLAIR sulcal hyperintensities (dot sign). Infarcts, if present, are usually symmetric and distributed along border zones of arterial territories. Intraparenchymal hemorrhage and/or nonaneurysmal convexity SAH may be present in some cases of RCVS. |
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