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Polymorphonuclear neutrophil (PMN) defects

Polymorphonuclear neutrophil (PMN) defects
Normal neutrophil functions in the circulation (pink background) and the tissues (gray background) are illustrated, along with inherited defects in each of the stages in response to pathogens (adhesion, chemotaxis, phagocytosis, and killing). Refer to UpToDate topics on individual syndromes and laboratory testing for these defects for additional information.
LAD: Leukocyte adhesion defect; CGD: chronic granulomatous disease.
Courtesy of Thomas Coates, MD
Graphic 100385 Version 1.0

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