One-year access to more than 500 world journals available in the system
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Price : 300$- Special Price : 100$
The Future of Drug-Pricing Transparency
William B. Feldman, M.D., D.Phil., M.P.H., Benjamin N. Rome, M.D., Jerry Avorn, M.D., and Aaron S. Kesselheim, M.D., J.D., M.P.H.
doi : 10.1056/NEJMp2033734
N Engl J Med 2021; 384:489-491
A Shared Evaluation Platform for Medical Training
John F. McConville, M.D., and James N. Woodruff, M.D.
doi : 10.1056/NEJMp2031317
N Engl J Med 2021; 384:491-493
Learning How to Die — Lessons from the Irish Wake
Rose M. Olson, M.D.
doi : 10.1056/NEJMp2030773
N Engl J Med 2021; 384:494-495
Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
WHO Solidarity Trial Consortium*
doi : 10.1056/NEJMoa2023184
N Engl J Med 2021; 384:497-511
World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs — remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a — in patients hospitalized with coronavirus disease 2019 (Covid-19).
Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis
Andrew Blauvelt, M.D., Steven Kempers, M.D., Edward Lain, M.D., Todd Schlesinger, M.D., Stephen Tyring, M.D., Ph.D., Seth Forman, M.D., Glynis Ablon, M.D., George Martin, M.D., Hui Wang, Ph.D., David L. Cutler, M.D., Jane Fang, M.B., B.S., and Min-Fun R. Kwan, M.B., B.S. for the Phase 3 Tirbanibulin for Actinic Keratosis Group*
doi : 10.1056/NEJMoa2024040
N Engl J Med 2021; 384:512-520
The tubulin polymerization and Src kinase signaling inhibitor tirbanibulin is being investigated as a topical treatment for actinic keratosis, a precursor of squamous-cell carcinoma.
Posture, Gait, Quality of Life, and Hearing with a Vestibular Implant
Margaret R. Chow, B.S., Andrianna I. Ayiotis, B.S., Desi P. Schoo, M.D., Yoav Gimmon, P.T., Ph.D., Kelly E. Lane, R.V.T., Brian J. Morris, B.S., Mehdi A. Rahman, M.S., Nicolas S. Valentin, M.S., Peter J. Boutros, Ph.D., Stephen P. Bowditch, Au.D., Bryan K. Ward, M.D., Daniel Q. Sun, M.D., Carolina Trevi?o Guajardo, M.D., Michael C. Schubert, P.T., Ph.D., John P. Carey, M.D., and Charles C. Della Santina, M.D., Ph.D.
doi : 10.1056/NEJMoa2020457
N Engl J Med 2021; 384:521-532
Bilateral vestibular hypofunction is associated with chronic disequilibrium, postural instability, and unsteady gait owing to failure of vestibular reflexes that stabilize the eyes, head, and body. A vestibular implant may be effective in alleviating symptoms.
Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers
Sheila F. Lumley, B.M., B.Ch., Denise O’Donnell, B.Sc., Nicole E. Stoesser, M.B., B.S., D.Phil., Philippa C. Matthews, F.R.C.P., D.Phil., Alison Howarth, Ph.D., Stephanie B. Hatch, Ph.D., Brian D. Marsden, D.Phil., Stuart Cox, Tim James, Ph.D., Fiona Warren, B.Sc., Liam J. Peck, D.Phil., Thomas G. Ritter, B.A., Zoe de Toledo, M.Sc., Laura Warren, David Axten, B.A., Richard J. Cornall, M.D., D.Phil., E. Yvonne Jones, D.Phil., David I. Stuart, Ph.D., Gavin Screaton, B.M., B.Ch., D.Phil., Daniel Ebner, B.Sc., Sarah Hoosdally, Ph.D., Meera Chand, M.B., B.S., Derrick W. Crook, F.R.C.Path., Anne-Marie O’Donnell, M.B., B.S., Christopher P. Conlon, M.D., Koen B. Pouwels, Ph.D., A. Sarah Walker, Ph.D., Tim E.A. Peto, F.R.C.P., Susan Hopkins, F.R.C.P., Timothy M. Walker, M.B., B.S., D.Phil., Katie Jeffery, F.R.C.Path., Ph.D., and David W. Eyre, B.M., B.Ch., D.Phil. for the Oxford University Hospitals Staff Testing Group*
doi : 10.1056/NEJMoa2034545
N Engl J Med 2021; 384:533-540
The relationship between the presence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the risk of subsequent reinfection remains unclear.
Randomized Trial of a Vaccine Regimen to Prevent Chronic HCV Infection
Kimberly Page, Ph.D., M.P.H., Michael T. Melia, M.D., Rebecca T. Veenhuis, Ph.D., Matthew Winter, D.D.S., Kimberly E. Rousseau, B.S., Guido Massaccesi, B.S., William O. Osburn, Ph.D., Michael Forman, B.S., Elaine Thomas, M.D., Karla Thornton, M.D., M.P.H., Katherine Wagner, M.I.P.H., Ventzislav Vassilev, Ph.D., Lan Lin, M.D., Paula J. Lum, M.D., M.P.H., Linda C. Giudice, M.D., Ph.D., Ellen Stein, M.P.H., Alice Asher, R.N., Ph.D., Soju Chang, M.D., Richard Gorman, M.D., Marc G. Ghany, M.D., M.H.Sc., T. Jake Liang, M.D., Michael R. Wierzbicki, Ph.D., Elisa Scarselli, M.D., Alfredo Nicosia, Ph.D., Antonella Folgori, Ph.D., Stefania Capone, B.S., and Andrea L. Cox, M.D., Ph.D.
doi : 10.1056/NEJMoa2023345
N Engl J Med 2021; 384:541-549
A safe and effective vaccine to prevent chronic hepatitis C virus (HCV) infection is a critical component of efforts to eliminate the disease.
Circadian Mechanisms in Medicine
Ravi Allada, M.D., and Joseph Bass, M.D., Ph.D.
doi : 10.1056/NEJMra1802337
N Engl J Med 2021; 384:550-561
Heart-Shaped Lesion
Sami Karapolat, M.D., and Mustafa Sisman, M.D.
doi : 10.1056/NEJMicm2024088
N Engl J Med 2021; 384:562
Case 4-2021: A 70-Year-Old Woman with Dyspnea on Exertion and Abnormal Findings on Chest Imaging
Richard M. Schwartzstein, M.D., Benjamin D. Medoff, M.D., Amita Sharma, M.D., Yolonda L. Colson, M.D., Justin Gainor, M.D., and Lida P. Hariri, M.D., Ph.D.
doi : 10.1056/NEJMcpc2027088
N Engl J Med 2021; 384:563-574
A Large, Simple Trial Leading to Complex Questions
David P. Harrington, Ph.D., Lindsey R. Baden, M.D., and Joseph W. Hogan, Sc.D.
doi : 10.1056/NEJMe2034294
N Engl J Med 2021; 384:576-577
Audio Interview: Does Vaccination Mean the End of Masking and Social Distancing?
Eric J. Rubin, M.D., Ph.D., Lindsey R. Baden, M.D., and Stephen Morrissey, Ph.D.
doi : 10.1056/NEJMe2102482
N Engl J Med 2021; 384:e32
Regulatory T Cells in Multiple Sclerosis
Joan M. Goverman, Ph.D.
doi : 10.1056/NEJMcibr2033544
N Engl J Med 2021; 384:578-580
Ustekinumab for Refractory Colitis Associated with Immune Checkpoint Inhibitors
doi : 10.1056/NEJMc2031717
N Engl J Med 2021; 384:581-583
Atezolizumab for PD-L1–Selected Patients with NSCLC
doi : 10.1056/NEJMc2032432
N Engl J Med 2021; 384:583-585
Evinacumab for Homozygous Familial Hypercholesterolemia
doi : 10.1056/NEJMc2033612
N Engl J Med 2021; 384:e17
