The Lancet Oncology




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Reviving the UK NHS: Labour's biggest challenge?

doi : 10.1016/S1470-2045(24)00525-4

Volume 25, Issue 10, October 2024, Page 1245

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A step closer to the use of [177Lu]Lu-PSMA-617 in metastatic hormone-sensitive prostate cancer

doi : 10.1016/S1470-2045(24)00506-0

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Treatment of Richter transformation—immunotherapy to the rescue?

doi : 10.1016/S1470-2045(24)00485-6

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Precision medicine with MET exon 14: a partial success

doi : 10.1016/S1470-2045(24)00492-3

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Diagnostic accuracy of risk prediction models in postmenopausal patients with suspected ovarian cancer

doi : 10.1016/S1470-2045(24)00450-9

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The UK needs to be a leader, not a lagger, in the global cancer effort

doi : 10.1016/S1470-2045(24)00448-0

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Radiation oncology: a call for papers for ESTRO 2025

doi : 10.1016/S1470-2045(24)00483-2

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Adverse obstetric outcomes in female survivors of adolescent and young adult cancers

doi : 10.1016/S1470-2045(24)00431-5

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Adverse obstetric outcomes in female survivors of adolescent and young adult cancers

doi : 10.1016/S1470-2045(24)00444-3

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Adverse obstetric outcomes in female survivors of adolescent and young adult cancers

doi : 10.1016/S1470-2045(24)00487-X

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Adverse obstetric outcomes in female survivors of adolescentand young adult cancers – Authors' reply

doi : 10.1016/S1470-2045(24)00512-6

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Investigating hidden influences on treatment for gastrointestinal stromal tumours with AI: diet, chronic conditions, and mental health

doi : 10.1016/S1470-2045(24)00449-2

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Investigating hidden influences on treatment for gastrointestinal stromal tumours with AI: diet, chronic conditions, and mental health – Authors' reply

doi : 10.1016/S1470-2045(24)00519-9

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NHS cancer services and systems: critical support for cancer care

doi : 10.1016/S1470-2045(24)00484-4

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Correction to Lancet Oncol 2024; 25: 989–1002

doi : 10.1016/S1470-2045(24)00509-6

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Medicare drug price negotiations by the US Government

doi : 10.1016/S1470-2045(24)00459-5

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Continued suboptimal HPV vaccine coverage in the USA

doi : 10.1016/S1470-2045(24)00394-2

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World's first lung cancer vaccine trial launched in the UK

doi : 10.1016/S1470-2045(24)00324-3

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New developments in tobacco control measures in Europe

doi : 10.1016/S1470-2045(24)00495-9

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European Commission approval for Dutch investment in radiopharmaceuticals

doi : 10.1016/S1470-2045(24)00496-0

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Petition to end travel insurance discrimination against people with cancer

doi : 10.1016/S1470-2045(24)00515-1

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Families of cancer victims wait for benefits decades after the World Trade Center attack

doi : 10.1016/S1470-2045(24)00526-6

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Using cancer to fuel art at the Edinburgh Festival Fringe

Peter Ranscombe

doi : 10.1016/S1470-2045(24)00455-8

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Losing my brother, finding myself

Jules Morgan

doi : 10.1016/S1470-2045(24)00489-3

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The Cancer Tapestry is telling a thousand stories

Peter Ranscombe

doi : 10.1016/S1470-2045(24)00490-X

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Sequential [177Lu]Lu-PSMA-617 and docetaxel versus docetaxel in patients with metastatic hormone-sensitive prostate cancer (UpFrontPSMA): a multicentre, open-label, randomised, phase 2 study

Arun A Azad PhD a b e, Mathias Bressel MSc c e, Hsiang Tan MBBS h j, Mark Voskoboynik MBBS k m, Aneta Suder MBChB n, Andrew J Weickhardt DMedSc o q, Alexander Guminski PhD r, Roslyn J Francis PhD t v, Javad Saghebi MBBS b e, Nattakorn Dhiantravan MBBS x, Prof Anthony M Joshua PhD y z, Prof Louise Emmett MBBS z aa ab, Prof Lisa Horvath PhD ac ad, Prof Declan G Murphy MCChB b d e, Edward Hsiao MBChB s, Bavanthi Balakrishnar MBBS ae, Peter Lin MBBS af, Andrew Redfern MBChB v ag, William Macdonald MBBS v ah, Siobhan Ng MBBS u w…L Ratnayake

doi : 10.1016/S1470-2045(24)00440-6

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[89Zr]Zr-girentuximab for PET–CT imaging of clear-cell renal cell carcinoma: a prospective, open-label, multicentre, phase 3 trial

Brian Shuch MD a, Allan J Pantuck MD a, Jean-Christophe Bernhard MD b, Michael A Morris MD c, Viraj Master MD d, Andrew M Scott MD e f g h, Charles van Praet MD i, Clement Bailly MD j, Bülent Önal MD k, Tamer Aksoy MD l, Robin Merkx MD m, David M Schuster MD n, Sze Ting Lee MD e f g h, Neeta Pandit-Taskar MD o p, Alice C Fan MD q, Phillip Allman PhD r, Karl Schmidt s, Libuse Tauchmanova MD t, Michael Wheatcroft PhD t, Christian Behrenbruch DPhil t…Peter Mulders MD u

doi : 10.1016/S1470-2045(24)00402-9

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Sintilimab combined with bevacizumab in relapsed or persistent ovarian clear cell carcinoma (INOVA): a multicentre, single-arm, phase 2 trial

Zikun Peng MD a *, Huayi Li MD a *, Yunong Gao MD b *, Li Sun MD c *, Jie Jiang MD d *, Bairong Xia MD e *, Yi Huang MD f, Yu Zhang MD g, Yu Xia PhD a, Yuxin Zhang MD a, Yiyang Shen BS a, Bowen Huang BS a, Jiayu Nie BS a, Xinrong Chen BS a, Xingyu Liu MD a, Cui Feng MD h, Zhen Li MD h, Wei Zhang MD a, Kangjia Tao MS a, Qiuxue Zhang PhD a…Prof Qinglei Gao MD a †

doi : 10.1016/S1470-2045(24)00437-6

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Atezolizumab, venetoclax, and obinutuzumab combination in Richter transformation diffuse large B-cell lymphoma (MOLTO): a multicentre, single-arm, phase 2 trial

Alessandra Tedeschi MD a †, Anna Maria Frustaci MD a †, Adalgisa Condoluci MD b c, Prof Marta Coscia MD e, Prof Roberto Chiarle MD f g h, Prof Pier Luigi Zinzani MD i j, Marina Motta MD k, Prof Gianluca Gaidano MD l, Giulia Quaresmini MD m, Lydia Scarfò MD n, Gioacchino Catania MD o, Marina Deodato MD a, Rebecca Jones MD d, Valentina Tabanelli MD f, Valentina Griggio PhD d, Prof Georg Stüssi MD c p, Angelica Calleri PhD f, Katia Pini BS b, Roberto Cairoli MD a, Thorsten Zenz MD q r…Marco Montillo MD a

doi : 10.1016/S1470-2045(24)00396-6

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Ziftomenib in relapsed or refractory acute myeloid leukaemia (KOMET-001): a multicentre, open-label, multi-cohort, phase 1 trial

Prof Eunice S Wang MD a *, Ghayas C Issa MD b *, Prof Harry P Erba MD c, Prof Jessica K Altman MD d, Pau Montesinos MD e, Stephane DeBotton MD f, Prof Roland B Walter MD g, Kristen Pettit MD h, Prof Michael R Savona MD i, Mithun Vinod Shah MD j, Marina Kremyanskaya MD k, Prof Maria R Baer MD l, Prof James M Foran MD m, Prof Gary Schiller MD n, Prof Lionel Adès MD o, Mael Heiblig MD p, Celine Berthon MD q, Pierre Peterlin MD r, Eduardo Rodríguez-Arbolí MD s, Olga Salamero MD t…Amir T Fathi MD w

doi : 10.1016/S1470-2045(24)00386-3

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Belzutifan for patients with von Hippel-Lindau disease-associated CNS haemangioblastomas (LITESPARK-004): a multicentre, single-arm, phase 2 study

Othon Iliopoulos MD a, Ane B Iversen MD PhD b, Vivek Narayan MD MSCE c, Benjamin L Maughan MD d, Kathryn E Beckermann MD PhD e, Stephane Oudard MD PhD f, Tobias Else MD g, Jodi K Maranchie MD h, Cynthia Muller Goldberg MD i, Wei Fu PhD i, Rodolfo F Perini MD i, Yanfang Liu MD PhD i, W Marston Linehan MD j, Ramaprasad Srinivasan MD PhD j, Eric Jonasch MD k

doi : 10.1016/S1470-2045(24)00389-9

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Palliative radiotherapy versus best supportive care in patients with painful hepatic cancer (CCTG HE1): a multicentre, open-label, randomised, controlled, phase 3 study

Prof Laura A Dawson MD a, Prof Jolie Ringash MD a, Alysa Fairchild MD b, Paul Stos BSc c, Kristopher Dennis MD d, Aamer Mahmud MD e, Teri Lynn Stuckless MD f, Francois Vincent MD g, Prof David Roberge MD h, Matthew Follwell MD i, Raimond K W Wong MD j, Derek J Jonker MD d, Prof Jennifer J Knox MD a, Prof Camilla Zimmermann MD a, Philip Wong MDCM a, Prof Aisling S Barry MD k, Marc Gaudet MD d, Prof Rebecca K S Wong MBChB a, Thomas G Purdie PhD a, Prof Dongsheng Tu PhD c…Prof Christopher J O'Callaghan PhD c

doi : 10.1016/S1470-2045(24)00438-8

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Efficacy and safety of immune checkpoint inhibitors for individuals with advanced EGFR-mutated non-small-cell lung cancer who progressed on EGFR tyrosine-kinase inhibitors: a systematic review, meta-analysis, and network meta-analysis

Yi Zhao MD a *, Ying He MD a b *, Wei Wang MD a *, Qi Cai MD a *, Fan Ge MD c *, Zisheng Chen MD d *, Jianqi Zheng MD a, Yuan Zhang MD a, Hongsheng Deng MD a, Ying Chen BSN a, Shen Lao MD a, Hengrui Liang MD a, Prof Wenhua Liang MD a †, Prof Jianxing He MD a †

doi : 10.1016/S1470-2045(24)00379-6

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Capmatinib in MET exon 14-mutated non-small-cell lung cancer: final results from the open-label, phase 2 GEOMETRY mono-1 trial

Jürgen Wolf MD a, Maximilian Hochmair MD b, Ji-Youn Han MD PhD c, Noemi Reguart MD PhD d e, Pierre-Jean Souquet MD f, Egbert F Smit MD PhD g, Sergey V Orlov MD PhD h, Johan Vansteenkiste MD PhD i, Makoto Nishio MD PhD j, Maja de Jonge MD PhD k, Wallace Akerley MD l m, Edward B Garon MD n, Harry J M Groen MD PhD o, Daniel S W Tan MD PhD p, Takashi Seto MD q, Garrett M Frampton PhD r, Anna Robeva MS s, Mariana Carbini MD t, Sylvie Le Mouhaer MSc u, Alejandro Yovine MD t…Rebecca S Heist MD x

doi : 10.1016/S1470-2045(24)00441-8

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Risk-prediction models in postmenopausal patients with symptoms of suspected ovarian cancer in the UK (ROCkeTS): a multicentre, prospective diagnostic accuracy study

Prof Sudha Sundar MPhil MRCOG a b, Ridhi Agarwal PhD c, Clare Davenport FFPH PhD c, Katie Scandrett MSc c s, Susanne Johnson FRCOG e, Partha Sengupta FRCOG f, Radhika Selvi-Vikram FRCOG g, Fong Lien Kwong MRCOG a, Sue Mallett PhD h, Caroline Rick PhD i, Prof Sean Kehoe FRCOG MD j, Prof Dirk Timmerman MD PhD k m, Prof Tom Bourne FRCOG PhD n, Prof Ben Van Calster PhD k l, Hilary Stobart MSc o, Prof Richard D Neal FRCGP PhD p, Prof Usha Menon MD PhD q r, Alex Gentry-Maharaj PhD q r, Lauren Sturdy BSc d, Ryan Ottridge MPhil d…Ranjit Manchanda

doi : 10.1016/S1470-2045(24)00406-6

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Development of a conceptual framework for an electronic patient-reported outcome (ePRO) system measuring symptoms and impacts of CAR T-cell therapies in patients with haematological malignancies

Foram Khatsuria MPH a b c, Christel McMullan PhD a b, Olalekan Lee Aiyegbusi PhD a b c d e, Karen L Shaw PhD a b, Roshina Iqbal BSc a, Francesca Kinsella PhD f, Keith Wilson FRCPath h, Lester Pyatt j, Marlene Lewis j, Sophie M R Wheldon MSc j k, David Burns PhD g, Prof Ronjon Chakraverty MB ChB b i, Prof Melanie Calvert PhD a b c d e, Sarah E Hughes PhD a b d e

doi : 10.1016/S1470-2045(24)00256-0

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Challenges and opportunities for early phase clinical trials of novel drug–radiotherapy combinations: recommendations from NRG Oncology, the American Society for Radiation Oncology (ASTRO), the American College of Radiology (ACR), the Sarah Cannon Research Institute, and the American College of Radiation Oncology (ACRO)

Zachary S Zumsteg MD a, Siddharth Sheth DO b, Prof Salma K Jabbour MD c, Krishnan R Patel MD d, Randall J Kimple MD PhD f, Prof Terence M Williams MD PhD g, Meng Xu-Welliver MD PhD h, Pedro A Torres-Saavedra PhD e, Prof Arta M Monjazeb MD PhD i, Prof Jyoti Mayadev MD j, Steven E Finkelstein MD l m n, Prof John M Buatti MD o, Sandip P Patel MD k, Prof Steven H Lin MD PhD p

doi : 10.1016/S1470-2045(24)00264-X

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Best practices and novel approaches for the preclinical development of drug–radiotherapy combinations for cancer treatment

Pataje G S Prasanna PhD a, Mansoor M Ahmed PhD b, Julie A Hong MS a, Prof C Norman Coleman MD a

doi : 10.1016/S1470-2045(24)00199-2

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A brave new framework for glioma drug development

Kelly M Hotchkiss PhD a †, Philipp Karschnia MD b c d †, Karisa C Schreck MD PhD e f, Marjolein Geurts MD g h, Prof Timothy F Cloughesy MD i, Prof Jason Huse MD PhD j k, Elizabeth S Duke MD l, Prof Justin Lathia PhD m n o, David M Ashley MBBS (Hon) PhD a, Edjah K Nduom MD p, Prof Georgina Long MBBS (Hons) PhD q r s, Kirit Singh MBBS a, Prof Anthony Chalmers FRCP PhD t, Prof Manmeet S Ahluwalia MD u, Prof Amy Heimberger MD v, Stephen Bagley MD MSCE w, Prof Tomoki Todo MD PhD x, Prof Roel Verhaak PhD y, Prof Patrick D Kelly MD MSCI z, Shawn Hervey-Jumper MD aa ab…Prof Mustafa Khasraw MD a

doi : 10.1016/S1470-2045(24)00190-6

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The tyranny of non-inferiority trials

Prof Ian F Tannock MD a b, Marc Buyse DSc c d, Mickael De Backer PhD c, Prof Helena Earl MD e, Prof Daniel A Goldstein MD b f g h, Prof Mark J Ratain MD b i, Prof Leonard B Saltz MD b j, Prof Gabe S Sonke MD k l, Garth W Strohbehn MD b m n

doi : 10.1016/S1470-2045(24)00218-3

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IVLBCL mimicking VEXAS syndrome

Kevin Shopsowitz MD PhD b, Alym Abdulla MD c, Habib Moshref Razavi MD PhD a b

doi : 10.1016/S1470-2045(24)00500-X

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