Journal of Clinical Oncology




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ALK Tyrosine Kinase Inhibitors Induced Weight Gain: More Refined Definition of Weight Gain, Glucagon-Like Peptide-1 Agonist Treatment, and Therapeutic Drug Monitoring of ALK+ Non–Small Cell Lung Cancer?

doi : 10.1200/JCO-24-02514

2025, Volume 43 (6)

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Redefining Available Therapy in Oncology Accelerated Approval Decisions

doi : 10.1200/JCO.24.00892

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Neoadjuvant Modified Infusional Fluorouracil, Leucovorin, and Oxaliplatin With or Without Radiation Versus Fluorouracil Plus Radiation for Locally Advanced Rectal Cancer: Updated Results of the FOWARC Study After a Median Follow-Up of 10 Years

doi : 10.1200/JCO-24-01676

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Body Weight Gain Associated With Alectinib in Patients With ALK+ Non–Small Cell Lung Cancer: Pooled Analysis of Individual Patient Data From Four Prospective Clinical Trials

doi : 10.1200/JCO-24-01579

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Second Primary Cancer Risks After Breast Cancer in BRCA1 and BRCA2 Pathogenic Variant Carriers

doi : 10.1200/JCO.24.01146

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Randomized Controlled Trial of Acceptance and Commitment Therapy for Fatigue Interference With Functioning in Metastatic Breast Cancer

doi : 10.1200/JCO.24.00965

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Cost-Effectiveness of Total Neoadjuvant Therapy With Selective Nonoperative Management for Locally Advanced Rectal Cancer: Analysis of Data From the Organ Preservation for Rectal Adenocarcinoma Trial

doi : 10.1200/JCO.24.00681

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Large-Scale Pharmacogenomics Analysis of Patients With Cancer Within the 100,000 Genomes Project Combining Whole-Genome Sequencing and Medical Records to Inform Clinical Practice

doi : 10.1200/JCO.23.02761

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Treatment Intensification With Either Fludarabine, AraC, G-CSF and Idarubicin, or Cladribine Plus Daunorubicin and AraC on the Basis of Residual Disease Status in Older Patients With AML: Results From the NCRI AML18 Trial

doi : 10.1200/JCO.24.00259

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Cyclin-Dependent Kinase 4/6 Inhibition as a Novel Therapy for Peritoneal Mucinous Carcinomatosis With GNAS Mutations

doi : 10.1200/JCO.24.00511

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ReNeu: A Pivotal, Phase IIb Trial of Mirdametinib in Adults and Children With Symptomatic Neurofibromatosis Type 1-Associated Plexiform Neurofibroma

doi : 10.1200/JCO.24.01034

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Second MEK Inhibitor Shows Promise in Neurofibromatosis Type 1 With Symptomatic Plexiform Neurofibromas Signaling Hope for Other RASopathies

doi : 10.1200/JCO-24-02375

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Accelerating the Future of Oncology Drug Development: The Role of Consortia in the Delivery of Precision Oncology Early Phase Clinical Trials

doi : 10.1200/JCO-24-01534

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Germline and Somatic Genomic Testing for Metastatic Prostate Cancer: ASCO Guideline

doi : 10.1200/JCO-24-02608

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Human Leukocyte Antigen Mismatching and the Role of Killer Cell Immunoglobulin-Like Receptor Mismatch in Hematopoietic Cell Transplantation for Hematologic Malignancies

doi : 10.1200/JCO-24-01869

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Reply to: Human Leukocyte Antigen Mismatching and the Role of Killer Cell Immunoglobulin-Like Receptor Mismatch in Hematopoietic Cell Transplantation for Hematologic Malignancies

doi : 10.1200/JCO-24-02388

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Significance of Up-Front Stereotactic Radiosurgery for Non–Small Cell Lung Cancer Patients With Brain Metastases in the Era of New Generation Tyrosine Kinase Inhibitors

doi : 10.1200/JCO-24-01876

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Reply to: Significance of Up-Front Stereotactic Radiosurgery for Non–Small Cell Lung Cancer Patients With Brain Metastases in the Era of New Generation Tyrosine Kinase Inhibitors

doi : 10.1200/JCO-24-02129

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Comment on the Definition and Interpretation of Complete Mesocolic Excision in the RELARC Trial

doi : 10.1200/JCO-24-02228

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Reply to: Comment on the Definition and Interpretation of Complete Mesocolic Excision in the RELARC Trial

doi : 10.1200/JCO-24-02307

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