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Associate Editorial Board
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doi : 10.1016/S0007-0912(21)00321-4
Volume 127, Issue 1, July 2021, Page ii
How relevant is stereoselectivity to the side-effects of ketamine?
Konrad Meissner, Thomas K. Henthorn
doi : 10.1016/j.bja.2021.03.017
Volume 127, Issue 1, July 2021, Pages 1-2
Waking the dragon: national audit in China and the benefits of having a NAP
J. Robert Sneyd, Tim M. Cook
doi : 10.1016/j.bja.2021.04.004
Volume 127, Issue 1, July 2021, Pages 2-5
Can anaesthetic technique influence cancer outcome? The next steps…
Donal J. Buggy, Bernhard Riedel, Daniel I. Sessler
doi : 10.1016/j.bja.2021.04.005
Volume 127, Issue 1, July 2021, Pages 5-7
High-flow nasal oxygen for gastrointestinal endoscopy improves respiratory safety
Peter Santer, Karuna Wongtangman, Mandeep S. Sawhney, Matthias Eikermann
doi : 10.1016/j.bja.2021.03.022
Volume 127, Issue 1, July 2021, Pages 7-11
Credibility of subgroup findings in clinical trials and meta-analyses
Paul Myles, Jessica Kasza, Tari Turner
doi : 10.1016/j.bja.2021.04.007
Volume 127, Issue 1, July 2021, Pages 11-14
Hip fracture characteristics and outcomes during COVID-19: a large retrospective national database review
Haoyan Zhong, Jashvant Poeran, Jiabin Liu, Lauren A. Wilson, Stavros G. Memtsoudis
doi : 10.1016/j.bja.2021.04.003
Volume 127, Issue 1, July 2021, Pages 15-22
The COVID-19 pandemic has impacted healthcare in various vulnerable patient subpopulations. However, data are lacking on the impact of COVID-19 on hip fractures, seen mainly in older patients. Using national claims data, we aimed to describe the epidemiology during the first COVID-19 wave in the USA.
Stereoselective ketamine effect on cardiac output: a population pharmacokinetic/pharmacodynamic modelling study in healthy volunteers
JasperKampMoniquevan VelzenLeonAartsMariekeNiestersAlbertDahanErikOlofsen
doi : 10.1016/j.bja.2021.02.034
Volume 127, Issue 1, July 2021, Pages 23-31
Ketamine has cardiac excitatory side-effects. Currently, data on the effects of ketamine and metabolite concentrations on cardiac output are scarce. We therefore developed a pharmacodynamic model derived from data from a randomised clinical trial. The current study is part of a larger clinical study evaluating the potential mitigating effect of sodium nitroprusside on the psychedelic effects of ketamine.
Preoperative lymphopaenia, mortality, and morbidity after elective surgery: systematic review and meta-analysis
JohannesSchroth†ValentinWeber†Timothy F.JonesAna GutierrezDel ArroyoSian M.HensonGareth L.Ackland
doi : 10.1016/j.bja.2021.02.023
Volume 127, Issue 1, July 2021, Pages 32-40
In the general adult population, lymphopaenia is associated with an increased risk for hospitalisation with infection and infection-related death. The quality of evidence and strength of association between perioperative lymphopaenia across different surgical procedures and mortality/morbidity has not been examined by systematic review or meta-analysis.
Current status of perioperative hypnotics, role of benzodiazepines, and the case for remimazolam: a narrative review
J. RobertSneyd1Pedro L.Gambus23Ann E.Rigby-Jones1
doi : 10.1016/j.bja.2021.03.028
Volume 127, Issue 1, July 2021, Pages 41-55
no abstract
National survey on sedation for gastrointestinal endoscopy in 2758 Chinese hospitals
ShujingZhou†ZiyuZhu†WanbingDaiSiyiQiWeitianTianYizheZhangXiaoZhangLiliHuangJieTianWeifengYuDiansanSu
doi : 10.1016/j.bja.2021.01.028
Volume 127, Issue 1, July 2021, Pages 56-64
Although sedation during gastrointestinal endoscopy is widely used in China, the characteristics of sedation use, including regional distribution, personnel composition, equipment used, and drug selection, remain unclear. The present study aimed to provide insights into the current practice and regional distribution of sedation for gastrointestinal endoscopy in China.
Comparison between epidural and intravenous analgesia effects on disease-free survival after colorectal cancer surgery: a randomised multicentre controlled trial
WiebkeFalk1AndersMagnuson2ChristinaEintrei3RagnarHenningsson4P?rMyrelid56PeterMatthiessen7AnilGupta8
doi : 10.1016/j.bja.2021.04.002
Volume 127, Issue 1, July 2021, Pages 65-74
Thoracic epidural analgesia (TEA) has been suggested to improve survival after curative surgery for colorectal cancer compared with systemic opioid analgesia. The evidence, exclusively based on retrospective studies, is contradictory.
Intraoperative opioid exposure, tumour genomic alterations, and survival differences in people with lung adenocarcinoma
James G.Connolly1Kay SeeTan2BrookeMastrogiacomo3JosephDycoco1RaulCaso1Gregory D.Jones1Patrick J.McCormick45FranciscoSanchez-Vega3TakeshiIrie45Joseph R.Scarpa5Hersh V.Gupta6Prasad S.Adusumilli17GaetanoRocco17James M.Isbell17Matthew J.Bott17Gregory W.Fischer45David R.Jones17Joshua S.Mincer45
doi : 10.1016/j.bja.2021.03.030
Volume 127, Issue 1, July 2021, Pages 75-84
Opioids have been linked to worse oncologic outcomes in surgical patients. Studies in certain cancer types have identified associations between survival and intra-tumoural opioid receptor gene alterations, but no study has investigated whether the tumour genome interacts with opioid exposure to affect survival.
Impact of differences in acute respiratory distress syndrome randomised controlled trial inclusion and exclusion criteria: systematic review and meta-analysis
RohitSaha1BenjaminAssouline1GeorginaMason1AbdelDouiri23CharlotteSummers4ManuShankar-Hari56
doi : 10.1016/j.bja.2021.02.027
Volume 127, Issue 1, July 2021, Pages 85-101
Control-arm mortality varies between acute respiratory distress syndrome (ARDS) RCTs.
Postoperative delirium mediates 180-day mortality in orthopaedic trauma patients
Juan C.Pedemonte12†HaoqiSun3†EstebanFranco-Garcia4CarmenZhou5MarilynHeng6Sadeq A.Quraishi7BrandonWestover389OluwaseunAkeju18
doi : 10.1016/j.bja.2021.03.033
Volume 127, Issue 1, July 2021, Pages 102-109
Frailty has been associated with increased incidence of postoperative delirium and mortality. We hypothesised that postoperative delirium mediates a clinically significant (?1%) percentage of the effect of frailty on mortality in older orthopaedic trauma patients.
Procedure-specific acute pain trajectory after elective total hip arthroplasty: systematic review and data synthesis
PaulPanzenbeck1Arvindvon Keudell2Girish P.Joshi3Claire X.Xu4KamenVlassakov1Kristin L.Schreiber1James P.Rathmell1PhilippLirk1
doi : 10.1016/j.bja.2021.02.036
Volume 127, Issue 1, July 2021, Pages 110-132
For most procedures, there is insufficient evidence to guide clinicians in the optimal timing of advanced analgesic methods, which should be based on the expected time course of acute postoperative pain severity and aimed at time points where basic analgesia has proven insufficient.
High-flow nasal oxygenation or standard oxygenation for gastrointestinal endoscopy with sedation in patients at risk of hypoxaemia: a multicentre randomised controlled trial (ODEPHI trial)
Mai-AnhNay1LucieFromont2†AxelleEugene2†Jean-LouisMarcueyz3Willy-SergeMfam3OlivierBaert4FrancisRemerand2CélineRavry5AdrienAuvet5ThierryBoulain1
doi : 10.1016/j.bja.2021.03.020
Volume 127, Issue 1, July 2021, Pages 133-142
We aimed to determine whether high-flow nasal oxygen could reduce the incidence of decreased peripheral oxygen saturation (SpO2) compared with standard oxygen in patients at risk of hypoxaemia undergoing gastrointestinal endoscopy under deep sedation.
Pulmonary volume-feedback and ventilatory pattern after bilateral lung transplantation using neurally adjusted ventilatory assist ventilation
GiacomoGrasselli12LuigiCastagna1ChiaraAbbruzzese1NadiaCorcione3NicolaBottino1AmedeoGuzzardella2Sebastiano MariaColombo2EleonoraCarlesso2TommasoMauri12ValeriaRossetti3AlessandroPalleschi4VittorioScaravilli1AlbertoZanella12AntonioPesenti12
doi : 10.1016/j.bja.2021.03.010
Volume 127, Issue 1, July 2021, Pages 143-152
Bilateral lung transplantation results in pulmonary vagal denervation, which potentially alters respiratory drive, volume-feedback, and ventilatory pattern. We hypothesised that Neurally Adjusted Ventilatory Assist (NAVA) ventilation, which is driven by diaphragm electrical activity (EAdi), would reveal whether vagally mediated pulmonary-volume feedback is preserved in the early phases after bilateral lung transplantation.
Real-time visualisation of peripheral nerve trauma during subepineural injection in pig brachial plexus using micro-ultrasound
AnuChandra1YohannesSoenjaya2JudyYan2PaulFelts3GraemeMcLeod4ChristineDemore25
doi : 10.1016/j.bja.2021.03.036
Volume 127, Issue 1, July 2021, Pages 153-163
Nerve damage is consistently demonstrated after subepineural injection in animal studies, but not after purposeful injection in patients participating in clinical studies. There is a need to better visualise nerves in order to understand the structural changes that occur during subepineural injection.
Complex regional pain syndrome: role of contralateral sensitisation
ChristopherDietz1Ann-KristinReinhold1FabiolaEscolano-Lozano2KatharinaMehling1LukasForer3MichaelaKress4Nurcan?çeyler5ClaudiaSommer5VioletaDimova2FrankBirklein2†Heike L.Rittner1†
doi : 10.1016/j.bja.2021.03.018
Volume 127, Issue 1, July 2021, Pages e1-e3
Clinical validation of pharmacokinetic/pharmacodynamic models for propofol infusion. Response to Br J Anaesth 2021: 126: e172-4
RemcoVellinga1Laura N.Hannivoort1Jeroen V.Koomen12PieterColin1Anthony R.Absalom1Michel M.R.F.Struys13Douglas J.Eleveld1
doi : 10.1016/j.bja.2021.03.021
Volume 127, Issue 1, July 2021, Pages e3-e5
Metabolic outcomes in patients with diabetes mellitus administered SGLT2 inhibitors immediately before emergency or elective surgery: single centre experience and recommendations
RayWang1BenjaminKave2EdwardMcIlroy2MervynKyi13Peter G.Colman13SpirosFourlanos13
doi : 10.1016/j.bja.2021.03.023
Volume 127, Issue 1, July 2021, Pages e5-e7
Major adverse cardiovascular events and anaesthetic management in pregnant women with cardiac disease: a retrospective, single-centre study
MorganRoué1BernardIung23AgnèsBourgeois-Moine4PhilippeMontravers135ElieKantor1
doi : 10.1016/j.bja.2021.03.032
Volume 127, Issue 1, July 2021, Pages e8-e10
Maternal hypotension and neonatal sequelae. Comment on Br J Anaesth 2020; 125: 588–95
AhmedHasaninMohamedAbdulatifMahaMostafa
doi : 10.1016/j.bja.2021.03.037
Volume 127, Issue 1, July 2021, Pages e10-e11
Obstetric neuraxial anaesthesia in the setting of immune thrombocytopenia and low platelet counts: call to participate in an international registry
Ann KingaMalinowski12MahaOthman34on behalf of theInternational Society on Thrombosis and Haemostasis' Women's Health Issues in Thrombosis and Haemostasis SSCPlatelet Physiology SSCPlatelet Immunology SSC
doi : 10.1016/j.bja.2021.03.024
Volume 127, Issue 1, July 2021, Pages e12-e13
A comparison of fascial plane blocks on quality of recovery for minimally invasive thoracic surgery. Comment on Br J Anaesth 2020; 125: 802–10
SoniaAbid12DavidMagee12Sian I.Jaggar1
doi : 10.1016/j.bja.2021.03.025
Volume 127, Issue 1, July 2021, Pages e14-e15
Increased opioid consumption after regional nerve blockade: association of fascia iliaca block with rebound pain in neck of femur fracture
MaddesonRiley12BenTassie23JulieGawthorne24RenataHadzic25JenniferStevens23
doi : 10.1016/j.bja.2021.03.034
Volume 127, Issue 1, July 2021, Pages e15-e17
Assessment of ventriculo-arterial coupling from peripheral waveform analysis in septic shock. Reply to Br J Anaesth 2021; 126: e101-2
AndreaMorelli1FilippoSanfilippo2Salvatore M.Romano3AntoineVieillard-Baron45
doi : 10.1016/j.bja.2021.03.027
Volume 127, Issue 1, July 2021, Pages e17-e19
Impact of sampling peritoneal fluid during emergency laparotomy on antimicrobial prescriptions in the ICU
SophiaMuschikElizaPyeChristopherGoodwinJoshuaButlerAndyGeorgiou
doi : 10.1016/j.bja.2021.03.031
Volume 127, Issue 1, July 2021, Pages e19-e20
Association between mutated Mas-related G-protein-coupled receptor-X2 and rocuronium-induced intraoperative anaphylaxis. Comment on Br J Anaesth 2020; 125: e448–50
YasuyukiSuzuki12ShuangLiu2FumitoKadoya1YasushiTakasaki3ToshihiroYorozuya3MasakiMogi2
doi : 10.1016/j.bja.2021.04.009
Volume 127, Issue 1, July 2021, Pages e21-e22
Mindfulness for patients undergoing surgery: a cost-effective and potentially underrated tool for improving outcomes
OscarEmanuel12KateGreenslade3MattLechner24NicholasEynon-Lewis4
doi : 10.1016/j.bja.2021.03.038
Volume 127, Issue 1, July 2021, Pages e22-e24
Perioperative fluid management and patient outcomes. Comment on Br J Anaesth 2021; 126: 720–9
GeraldIhra1ThomasHamp1CarmenGore2
doi : 10.1016/j.bja.2021.04.011
Volume 127, Issue 1, July 2021, Pages e24-e25
Formula for safe insertion depth of a pulmonary artery catheter
RolandWalz1SebastianRoth1Markus W.Hollmann2RagnarHuhn1
doi : 10.1016/j.bja.2021.04.012
Volume 127, Issue 1, July 2021, Pages e25-e27
Diversity of residency applicants to anaesthesiology and other specialties in the USA from 2014 to 2019
Gianni R.Lorello1234Julie K.Silver5678Laura E.Flores9Allison R.Larson10KristianMcCarthy11Charles A.Odonkor12Alana M.Flexman1314
doi : 10.1016/j.bja.2021.04.013
Volume 127, Issue 1, July 2021, Pages e27-e30
Calculating positive and negative predictive values. Correction to Br J Anaesth 2021; 126: 564–7
GeorgeHadjipavlou1RichardSiviter2BirteFeix2
doi : 10.1016/j.bja.2021.03.014
Volume 127, Issue 1, July 2021, Pages e30-e31
Anaesthesia-related drugs and SARS-CoV-2 infection
KazuyoshiHirota1David G.Lambert2
doi : 10.1016/j.bja.2021.03.026
Volume 127, Issue 1, July 2021, Pages e32-e34
Effectiveness of anaesthesia ventilator use for mechanical ventilation in critically ill patients during the COVID-19 pandemic
AurélieGouel-Cheron123YoannElmaleh1CamilleCouffignal56ElieKantor1SimonMeslin7AnaïsCaillard89ArthurSalome10SophieHamada7BernardCholley7AlexandreMebazaa489DanLongrois141112Jean-LouisBourgain10ValérieBillard10FrédériqueServin1PhilippeMontravers1413
doi : 10.1016/j.bja.2021.04.001
Volume 127, Issue 1, July 2021, Pages e35-e37
Biological, psychological, and social factors associated with worsening of chronic pain during the first wave of the COVID-19 pandemic: a cross-sectional survey
KordulaLang-IllievichGudrunRumpold-SeitlingerIstvan S.SzilagyiChristianDornMichaelaSailerGregor A.SchittekChristophKlivinyiHelmarBornemann-Cimenti
doi : 10.1016/j.bja.2021.04.010
Volume 127, Issue 1, July 2021, Pages e37-e39
ICU Quick Drug Guide, Jennifer Pai Lee. Published by Elsevier (2021), Pp. 368. Price £35.99. ISBN: 978-0-32368047-9
AnnaBatchelor
doi : 10.1016/j.bja.2021.02.015
Volume 127, Issue 1, July 2021, Pages 164-165
