One-year access to more than 500 world journals available in the system
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http://medilib.ir
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Price : 300$- Special Price : 100$
The cytoplasmic sensor, the AIM2 inflammasome: A precise therapeutic target in vascular and metabolic diseases
Jiuguo Lin, Jiaojiao Wang, Jian Fang, Meihang Li, Suowen Xu, Peter J. Little, Dongmei Zhang, Zhiping Liu
doi : 10.1111/bph.16355
Pharmacology of erenumab in human isolated coronary and meningeal arteries: Additional effect of gepants on top of a maximum effect of erenumab
Tessa de Vries, EloÃsa Rubio-Beltrán, Antoon van den Bogaerdt, Ruben Dammers, A. H. Jan Danser, Josefin Snellman, Jeanine Bussiere, Antoinette MaassenVanDenBrink
doi : 10.1111/bph.16322
An orally available Cav2.2Â calcium channel inhibitor for the treatment of neuropathic pain
Janine Kutzsche, Gustavo A. Guzman, Antje Willuweit, Olaf Kletke, Esther Wollert, Ian Gering, Dagmar Jürgens, Jörg Breitkreutz, Holger Stark, Annette G. Beck-Sickinger, Nikolaj Klöcker, Patricia Hidalgo, Dieter Willbold
doi : 10.1111/bph.16309
Why classical receptor theory, which ignores allostery, can effectively measure the strength of an allosteric effect as agonist's efficacy
H. Ongun Onaran, Tommaso Costa
doi : 10.1111/bph.16327
Ginsenosides retard atherogenesis via remodelling host–microbiome metabolic homeostasis
Yun Wang, Jiawei Wu, Yu Hong, Jiaying Zhu, Youcai Zhang, Jun Zhang, Chujie Ding, Yuan Che, Guangji Wang, Aiqin Jiang, Haiping Hao, Lijuan Cao
doi : 10.1111/bph.16320
Voltage tunes mGlu5Â receptor function, impacting synaptic transmission
Marin Boutonnet, Camille Carpena, Nathalie Bouquier, Yan Chastagnier, Joan Font-Ingles, Enora Moutin, Ludovic Tricoire, Jean Chemin, Julie Perroy
doi : 10.1111/bph.16317
Complement tunes glutamate release and supports synaptic impairments in an animal model of multiple sclerosis
Guendalina Olivero, Alice Taddeucci, Giulia Vallarino, Hanna Trebesova, Alessandra Roggeri, Maria Cristina Gagliani, Katia Cortese, Massimo Grilli, Anna Pittaluga
doi : 10.1111/bph.16328
Are insulin sensitizers the new strategy to treat Type 1 diabetes? A long-acting dual amylin and calcitonin receptor agonist improves insulin-mediated glycaemic control and controls body weight
Simone Anna Melander, Anna Thorsø Larsen, Morten Asser Karsdal, Kim Henriksen
doi : 10.1111/bph.16329
Andrographolide regulates H3 histone lactylation by interfering with p300 to alleviate aortic valve calcification
Chunli Wang, Shunshun Wang, Zijun Wang, Juanjuan Han, Nan Jiang, Linghang Qu, Kang Xu
doi : 10.1111/bph.16332
Holotoxin A1 from Apostichopus japonicus inhibited oropharyngeal and intra-abdominal candidiasis by inducing oxidative damage in Candida albicans
Min Liao, Xuekui Xia, Qingzhou Meng, Chengguang Zhu, Binyou Liao, Jiannan Wang, Lichen Gou, Xuedong Zhou, Wenpeng Yuan, Lei Cheng, Biao Ren
doi : 10.1111/bph.16333
Characterisation of cotadutide's dual GLP-1/glucagon receptor agonistic effects on glycaemic control using an in vivo human glucose regulation quantitative systems pharmacology model
Rolien Bosch, Marcella Petrone, Rosalin Arends, Paolo Vicini, Eric J. G. Sijbrands, Sven Hoefman, Nelleke Snelder
doi : 10.1111/bph.16336
Radiprodil, a selective GluN2B negative allosteric modulator, rescues audiogenic seizures in mice carrying the GluN2A(N615S) mutation
Ilaria Bertocchi, Lorenzo Cifarelli, Alessandra Oberto, Carola Eugenia Eva, Rolf Sprengel, Naheed Rohman Mirza, Pierandrea Muglia
doi : 10.1111/bph.16361
