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Evidence of a pan-tissue decline in stemness during human aging
Gabriel Arantes dos Santos, Gustavo Daniel Vega Magdaleno, João Pedro de Magalhães
doi : 10.18632/aging.205717
Volume 16, Issue 7
The impact of continuous and intermittent ketogenic diets on cognitive behavior, motor function, and blood lipids in TgF344-AD rats
Jennifer M. Rutkowsky, Zabrisky Roland, Anthony Valenzuela, An B. Nguyen, Heui Hye Park, Natalie Six, Ilknur Dursun, Kyoungmi Kim, Pamela J. Lein, Jon J. Ramsey
doi : 10.18632/aging.205741
The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background
Stephen A. Banse, E. Grace Jackson, Christine A. Sedore, Brian Onken, David Hall, Anna Coleman-Hulbert, Phu Huynh, Theo Garrett, Erik Johnson, Girish Harinath, Delaney Inman, Suzhen Guo, Mackenzie Morshead, Jian Xue, Ron Falkowski, Esteban Chen, Christopher Herrera, Allie J. Kirsch, Viviana I. Perez, Max Guo, Gordon J. Lithgow, Monica Driscoll, Patrick C. Phillips
doi : 10.18632/aging.205743
miR-30d-5p inhibits proliferation, invasion and migration of breast cancer cells by targeting SERPINE1 and promoting fatty acid β-oxidation
Lina Zhang, Shuguang Ren, Yang Sang, Yueyang Hu, Cong Wang, Xinrui Wang, Yuntao Li
doi : 10.18632/aging.205587
NXPH4 can be used as a biomarker for pan-cancer and promotes colon cancer progression
Zhipeng Zhang, Pengfei Wang, Siwen Chen, Dezhi Xiang, Jinzhen Chen, Wanchang Huang, Xiao Liu, Tongwen Yi, Dawei Wang, Yunfei Pu, Longfu He, Hao Zhang
doi : 10.18632/aging.205648
Cordyceps sinensis extract protects against acute kidney injury by inhibiting perforin expression in NK cells via the STING/IRF3 pathway
Shuang Li, Wei Pang, Yuzhu Wang, Yiting Zhang
doi : 10.18632/aging.205676
Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway
Yunfang Yang, Changjiang Li, Sijin Yang, Zhuo Zhang, Xue Bai, Hongmei Tang, Jiang Huang
doi : 10.18632/aging.205678
Downregulating miRNA-199a-5p exacerbates fluorouracil-induced cardiotoxicity by activating the ATF6 signaling pathway
Wei Wang, Liang Dong, Hengxu Lv, Yonghui An, Changwang Zhang, Zheng Zheng, Ying Guo, Li He, Libin Wang, Jinmei Wang, Xinlei Shi, Na Li, Mingqi Zheng
doi : 10.18632/aging.205679
RNA splicing regulator EIF3D regulates the tumor microenvironment through immunogene-related alternative splicing in head and neck squamous cell carcinoma
Dandan Lu, Mijti Mihoayi, Yimin Ablikim, Abdeyrim Arikin
doi : 10.18632/aging.205681
Identification of key pathways and mRNAs in interstitial cystitis/bladder pain syndrome treatment with quercetin through bioinformatics analysis of mRNA-sequence data
Guang Wang, Pei Li, Si-Wei Su, Rui Xu, Zi-Ye Huang, Tong-Xin Yang, Jiong-Ming Li
doi : 10.18632/aging.205682
Identification and validation of DHCR7 as a diagnostic biomarker involved in the proliferation and mitochondrial function of breast cancer
Yanfeng Wang, Jiaxin Fan, Yongcheng Liu, Jie Du, Boyu Liang, Huxia Wang, Zhangjun Song
doi : 10.18632/aging.205683
Identification and validation of the biomarkers related to ferroptosis in calcium oxalate nephrolithiasis
Chao Hou, Bing Zhong, Shuo Gu, Yunyan Wang, Lu Ji
doi : 10.18632/aging.205684
Novel insights into the pathogenesis of thyroid eye disease through ferroptosis-related gene signature and immune infiltration analysis
Yunyan Ye, Lei Dai, Joseph Mugaanyi, Weina Fu, Feng Hu
doi : 10.18632/aging.205685
Exploration of signature based on T cell-related genes in stomach adenocarcinoma by analysis of single cell sequencing data
Huimei Wang, Nan An, Aiyue Pei, Yongxiao Sun, Shuo Li, Si Chen, Nan Zhang
doi : 10.18632/aging.205687
Identification of a novel disulfideptosis-related gene signature for prognostic implication in lower-grade gliomas
Fuqiang Zhang, Meihong Lv, Yi He
doi : 10.18632/aging.205688
Associations of PD-1 and PD-L1 gene polymorphisms with cancer risk: a meta-analysis based on 50 studies
Maoquan Yang, Yan Liu, Shuangshuang Zheng, Peizhen Geng, Tianhao He, Linan Lu, Yikuan Feng, Qiqi Jiang
doi : 10.18632/aging.205689
The necroptosis-related signature and tumor microenvironment immune characteristics associated with clinical prognosis and drug sensitivity analysis in stomach adenocarcinoma
Biao Yang, Yingnan Wang, Tao Liu, Meijing Zhang, Tianhang Luo
doi : 10.18632/aging.205690
A novel risk signature based on liquid-liquid phase separation-related genes reveals prognostic and tumour microenvironmental features in clear cell renal cell carcinoma
Qing Lu, Ping Xi, Suling Xu, Zhicheng Zhang, Binbin Gong, Ji Liu, Qiqi Zhu, Ting Sun, Shaoxing Zhu, Ru Chen
doi : 10.18632/aging.205691
Lifibrate attenuates blood-brain barrier damage following ischemic stroke via the MLCK/p-MLC/ZO-1 axis
Yu Duan, Yao Deng, Feng Tang, Jian Li
doi : 10.18632/aging.205692
Poria cocos polysaccharides improve alcoholic liver disease by interfering with ferroptosis through NRF2 regulation
Xiangyu Zhou, Jincheng Wang, Sufang Zhou
doi : 10.18632/aging.205693
KIF3C: an emerging biomarker with prognostic and immune implications across pan-cancer types and its experiment validation in gastric cancer
Qiangqiang Zhong, Wenbo Hong, Lina Xiong
doi : 10.18632/aging.205694
Potential value of expression of receptor accessory protein 4 for evaluating the prognosis of lower-grade glioma patients
Shuping Luo, Zhendong Liu, Haigang Chang, Xingbo Cheng, Rongjun Qian, Yanzheng Gao, Chaofeng Hou
doi : 10.18632/aging.205695
A retrospective study on the effect of Chinese patent medicine combined with conventional treatment on the survival outcomes of 313 patients with stage II–III NSCLC
Kegang Jia, Chenxu Zhang, Fang Li, Bin He, Shenglong Xie, Jun Du, Gang Feng
doi : 10.18632/aging.205697
Role of CCR1/5/7 in hepatocellular carcinoma: a study on prognostic evaluation, molecular subtyping, and association with immune infiltration
Huasheng Huang, Chenlu Lan, Yongguang Wei, Jusen Nong, Xiwen Liao, Xinping Ye, Ganlu Deng, Tao Peng, Xin Zhou
doi : 10.18632/aging.205698
Identification and characterization of circular RNAs expression profiles in obstructive sleep apnea-induced liver injury
Chaowei Li, Jinhuang Lin, Qingshi Chen, Yueyong Zhu
doi : 10.18632/aging.205701
Human umbilical cord-derived mesenchymal stem cells and auto-crosslinked hyaluronic acid gel complex for treatment of intrauterine adhesion
Jiaying Fan, Jingying Xie, Yunsheng Liao, Baoyu Lai, Guixin Zhou, Wenqin Lian, Jian Xiong
doi : 10.18632/aging.205704
Identifying an immunogenic cell death-related gene signature contributes to predicting prognosis, immunotherapy efficacy, and tumor microenvironment of lung adenocarcinoma
Xue Li, Dengfeng Zhang, Pengfei Guo, Shaowei Ma, Shaolin Gao, Shujun Li, Yadong Yuan
doi : 10.18632/aging.205705
Machine learning identifies novel coagulation genes as diagnostic and immunological biomarkers in ischemic stroke
Jinzhi Liu, Zhihua Si, Ju Liu, Xu Zhang, Cong Xie, Wei Zhao, Aihua Wang, Zhangyong Xia
doi : 10.18632/aging.205706
Lactobacillus plantarum 45 activates SHP2 through inhibition of oxidative stress to regulate osteoblast and osteoclast differentiation
Yaming Yang, Zheng Yan, Qi Xie, Yong Wang, Zhiying Liu, Min Lei
doi : 10.18632/aging.205708
Inflammatory risk of albumin combined with C-reactive protein predicts long-term cardiovascular risk in patients with diabetes
Xiaoqun Xu, Houyong Zhu, Hanxin Wang, Xinyu Zhu, Libin Liu, Fengwei Zhang, Hongjuan Zhou, Mingzhi Zhu, Lingshan Dai, Long Cai
doi : 10.18632/aging.205709
Metabolic score for insulin resistance predicts major adverse cardiovascular event in premature coronary artery disease
Dachuan Guo, Chong Zhang, Mingyan Zhang, Zhenguo Wu, Xiaoyu Liu, Yerui Zhang, Li Liu, Meili Sun, Jianmin Yang
doi : 10.18632/aging.205710
Using genetics and proteomics data to identify proteins causally related to COVID-19, healthspan and lifespan: a Mendelian randomization study
Jie V. Zhao, Minhao Yao, Zhonghua Liu
doi : 10.18632/aging.205711
Pan-cancer analysis of Sushi domain-containing protein 4 (SUSD4) and validated in colorectal cancer
Yuchen Zhong, Chaojing Zheng, Weiyuan Zhang, Hongyu Wu, Qian Zhang, Dechuan Li, Haixing Ju, Haiyang Feng, Yinbo Chen, Yongtian Fan, Weiping Chen, Meng Wang, Guiyu Wang
doi : 10.18632/aging.205712
Risk assessment of extra-uterine involvement and prognosis in young type I endometrial carcinoma with high or moderate differentiation and less than 1/2 myometrial invasion
Yi Sun, Pin Han, Yuanpei Wang, Xiaoran Cheng, Weijia Wu, Qianwen Liu, Fang Ren
doi : 10.18632/aging.205714
Machine learning for identifying tumor stemness genes and developing prognostic model in gastric cancer
Guo-Xing Li, Yun-Peng Chen, You-Yang Hu, Wen-Jing Zhao, Yun-Yan Lu, Fu-Jian Wan, Zhi-Jun Wu, Xiang-Qian Wang, Qi-Ying Yu
doi : 10.18632/aging.205715
Stigmasterol alleviates airway inflammation in OVA-induced asthmatic mice via inhibiting the TGF-β1/Smad2 and IL-17A signaling pathways
Sihong Huang, Rong Zhou, Yuyun Yuan, Yiyun Shen
doi : 10.18632/aging.205716
Multidimensional data analysis revealed thyroiditis-associated TCF19 SNP rs2073724 as a highly ranked protective variant in thyroid cancer
Xianhui Ruan, Yu Liu, Shuping Wu, Guiming Fu, Mei Tao, Yue Huang, Dapeng Li, Songfeng Wei, Ming Gao, Shicheng Guo, Junya Ning, Xiangqian Zheng
doi : 10.18632/aging.205718
has-miR-134-5p inhibits the proliferation and migration of glioma cells by regulating the BDNF/ERK signaling pathway
Zeshang Guo, Pingxv An, Xinyu Hong
doi : 10.18632/aging.205720
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H2S generation
Tursunay Dilxat, Qiang Shi, Xiaofan Chen, Xuxin Liu
doi : 10.18632/aging.205721
A prognostic signature established based on genes related to tumor microenvironment for patients with hepatocellular carcinoma
Zhongfeng Cui, Ge Li, Yanbin Shi, Xiaoli Zhao, Juan Wang, Shanlei Hu, Chunguang Chen, Guangming Li
doi : 10.18632/aging.205722
Single-cell data revealed exhaustion of characteristic NK cell subpopulations and T cell subpopulations in hepatocellular carcinoma
Zhongfeng Cui, Hongzhi Li, Chunli Liu, Juan Wang, Chunguang Chen, Shanlei Hu, Xiaoli Zhao, Guangming Li
doi : 10.18632/aging.205723
Transcranial direct current stimulation promotes angiogenesis and improves neurological function via the OXA-TF-AKT/ERK signaling pathway in traumatic brain injury
Bingkai Ren, Junwei Kang, Yan Wang, Xiangqiang Meng, Ying Huang, Yang Bai, Zhen Feng
doi : 10.18632/aging.205724
TGF-β downstream of Smad3 and MAPK signaling antagonistically regulate the viability and partial epithelial–mesenchymal transition of liver progenitor cells
Yi-Min Sun, Yu Wu, Gan-Xun Li, Hui-Fang Liang, Tu-Ying Yong, Zifu Li, Bixiang Zhang, Xiao-Ping Chen, Guan-Nan Jin, Ze-Yang Ding
doi : 10.18632/aging.205725
The mechanism of USP43 in the development of tumor: a literature review
Ziqi Zhao, Meichen Liu, Zhikun Lin, Mengru Zhu, Linlin Lv, Xinqing Zhu, Rui Fan, Abdullah Al-Danakh, Hui He, Guang Tan
doi : 10.18632/aging.205731
Correction for: Inhibition of circulating exosomal microRNA-15a-3p accelerates diabetic wound repair
Yuan Xiong, Lang Chen, Tao Yu, Chenchen Yan, Wu Zhou, Faqi Cao, Xiaomeng You, Yingqi Zhang, Yun Sun, Jing Liu, Hang Xue, Yiqiang Hu, Dong Chen, Bobin Mi, Guohui Liu
doi : 10.18632/aging.205514
Correction for: MTDH promotes metastasis of clear cell renal cell carcinoma by activating SND1-mediated ERK signaling and epithelial-mesenchymal transition
Anbang He, Shiming He, Cong Huang, Zhicong Chen, Yucai Wu, Yanqing Gong, Xuesong Li, Liqun Zhou
doi : 10.18632/aging.205603
