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Assembly of In-Situ Gel Containing Nano-Spanlastics of an Angiotensin II Inhibitor as a Novel Epitome for Hypertension Management: Factorial Design Optimization, In-vitro Gauging, Pharmacokinetics, and Pharmacodynamics Appraisal

doi : 10.1208/s12249-024-02823-9

Volume 25, Issue 5

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Accelerative Solid-State Oxidation Behaviour of Amorphous and Partially Crystalline Venetoclax

Jesús Alberto Afonso Urich, Viktoria Marko, Katharina Boehm, Bernd Werner, Klaus Zangger, Isha Saraf, Amrit Paudel & Varun Kushwah

doi : 10.1208/s12249-024-02832-8

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Oral In-Situ Nanoplatform with Balanced Hydrophobic-Hydrophilic Property for Transport Across Gastrointestinal Mucosa

Esha S. Attar, S. Jayakumar & Padma V. Devarajan

doi : 10.1208/s12249-024-02824-8

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Propellant Free Pressurized Spray System of Etodolac to Manage Acute Pain Conditions: In Vitro and In Vivo Evaluation

Shagun Saini, Bindu Soni, Manjot Kaur, Shubham Thakur, Riya Shivgotra, Navid Reza Shahtaghi & Subheet Kumar Jain

doi : 10.1208/s12249-024-02807-9

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Exploring the Potential of Artificial Intelligence as a Facilitating Tool for Formulation Development in Fluidized Bed Processor: a Comprehensive Review

Aachal A. Gosavi, Tanaji D. Nandgude, Rakesh K. Mishra & Dhiraj B. Puri

doi : 10.1208/s12249-024-02816-8

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LL37 Microspheres Loaded on Activated Carbon-chitosan Hydrogel: Anti-bacterial and Anti-toxin Wound Dressing for Chronic Wound Infections

Bee-Yee Lim, Fazren Azmi & Shiow-Fern Ng

doi : 10.1208/s12249-024-02826-6

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Real-Time Particle Emission Monitoring for the Non-Invasive Prediction of Lung Deposition via a Dry Powder Inhaler

Sakiko Hatazoe, Daiki Hira, Tetsuri Kondo, Satoshi Ueshima, Tomonobu Okano, Satoshi Hamada, Susumu Sato, Tomohiro Terada & Mikio Kakumoto

doi : 10.1208/s12249-024-02825-7

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Therapeutic Potential of Nanocarrier Mediated Delivery of Peptides for Wound Healing: Current Status, Challenges and Future Prospective

Mohit Kumar, Dikshant Kumar, Devesh Kumar, Yogesh Garg, Shruti Chopra & Amit Bhatia

doi : 10.1208/s12249-024-02827-5

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Self Emulsifying Delivery System of Cissus quadrangularis: Evidence of Enhanced Efficacy and Promising Pharmacokinetic Profile in the Management of Osteoporosis

Jaspreet Garg, Gargi Ghoshal, Gajanand Sharma, O. P. Katare & Sanjay Bhadada

doi : 10.1208/s12249-024-02821-x

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Exploring the Biofilm Inhibition Potential of a Novel Phytic Acid-Crosslinked Chitosan Nanoparticle: In Vitro and In Vivo Investigations

Reena Nayak, Vineet Kumar Rai, Deepak Pradhan, Jitu Halder, Tushar Kanti Rajwar, Priyanka Dash, Chandan Das, Ajit Mishra, Ritu Mahanty, Ivy Saha, Salim Manoharadas, Biswakanth Kar, Goutam Ghosh & Goutam Rath

doi : 10.1208/s12249-024-02829-3

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Optimizing Process Parameters for Controlled Drug Delivery: A Quality by Design (QbD) Approach in Naltrexone Microspheres

P. Lakshmikanth Reddy & Sangeetha Shanmugasundaram

doi : 10.1208/s12249-024-02830-w

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Nanocarrier – Mediated Salinomycin Delivery Induces Apoptosis and Alters EMT Phenomenon in Prostate Adenocarcinoma

Sonam Kanchan, Disha Marwaha, Bhawna Tomar, Sristi Agrawal, Sakshi Mishra, Radhika Kapoor, Sushma, Gaurav Jha, Divyansh Sharma, Rabi Sankar Bhatta, Prabhat Ranjan Mishra & Srikanta Kumar Rath

doi : 10.1208/s12249-024-02817-7

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Implications of Low-concentration Polymer on the Physical Stability of Glassy Griseofulvin: Role of the Segmental Mobility

Yanan Wang, Chai-Yee Chin, Naveen Kumar Hawala Shivashekaregowda & Qin Shi

doi : 10.1208/s12249-024-02809-7

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Characterization of Freezing Processes in Drug Substance Bottles by Ice Core Sampling

Sarah S. Peláez, Hanns-Christian Mahler, Pau Rubirola Vila, Jörg Huwyler & Andrea Allmendinger

doi : 10.1208/s12249-024-02818-6

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Transdermal Delivery of Niacin Through Polysaccharide Films Ameliorates Cutaneous Flushing in Experimental Wistar Rats

Aaqib Javaid, Aakriti Singh, Krishana Kumar Sharma, K. A. Abutwaibe, Kanika Arora, Anurag Verma & Shyam Lal Mudavath

doi : 10.1208/s12249-024-02812-y

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In Vitro In Vivo Extrapolation and Bioequivalence Prediction for Immediate-Release Capsules of Cefadroxil Based on a Physiologically-Based Pharmacokinetic ACAT Model

Najia Rahim & Syed Baqir Shyum Naqvi

doi : 10.1208/s12249-024-02811-z

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Optimization of Hypericum Perforatum Microencapsulation Process by Spray Drying Method

Fadime Seyrekoğlu, Hasan Temiz, Ferda Eser & Cengiz Yıldırım

doi : 10.1208/s12249-024-02820-y

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Skin- and Eco-Friendly Hand Sanitizer: A Novel Composition of Natural Extracts to Prevent the Spread of Respiratory Viruses

Marina Gomes, Isabella Dai Prá Zuchi, Catielen Paula Pavi, Gislaine Fongaro, Izabella Thaís da Silva & Bianca Ramos Pezzini

doi : 10.1208/s12249-024-02808-8

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QbD Enabled Development and Evaluation of Pazopanib Loaded Nanoliposomes for PDAC Treatment

Aishwarya Shinde, Kanan Panchal, Parameswar Patra, Sonali Singh, Sucharitha Enakolla, Rishi Paliwal & Akash Chaurasiya

doi : 10.1208/s12249-024-02806-w

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In-depth Mechanism, Challenges, and Opportunities of Delivering Therapeutics in Brain Using Intranasal Route

Arya Ghosh, Ankit Majie, Varnita Karmakar, Kaberi Chatterjee, Swarup Chakraborty, Manisha Pandey, Neha Jain, Suparna Roy Sarkar, Anroop B. Nair & Bapi Gorain

doi : 10.1208/s12249-024-02810-0

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Verapamil-Loaded Cubosomes for Enhancing Intranasal Drug Delivery: Development, Characterization, Ex Vivo Permeation, and Brain Biodistribution Studies

Mennatullah M. Faisal, Eman Gomaa, Adel Ehab Ibrahim, Sami El Deeb, Ahmed Al-Harrasi & Tarek M. Ibrahim

doi : 10.1208/s12249-024-02814-w

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Nanofiber-based Delivery of Luliconazole: Fabrication, Characterization, and Therapeutic Performance Assessment

Gauri Nimhan, Mahaveer Narwade, Rajesh Singh Jadon & Kavita Gajbhiye

doi : 10.1208/s12249-024-02815-9

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HSPiP, Computational, and Thermodynamic Model–Based Optimized Solvents for Subcutaneous Delivery of Tolterodine Tartrate and GastroPlus-Based In Vivo Prediction in Humans: Part I

Abdul Malik, Tasneem Khan, Mohd Usman Mohd Siddique, Abdul Faruk, Ashwani Kumar Sood & Zahid Rafiq Bhat

doi : 10.1208/s12249-024-02800-2

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Silk Fibroin Formed Bioadhesive Ophthalmic Gel for Dry Eye Syndrome Treatment

Tianjiao Hao, Lu Tang, Qianzi Xu, Wei Wang, Zengjing Li, Yan Shen, Bohui Xu, Hao Luo, Qian Li, Jirong Wang & Jinling Zhang

doi : 10.1208/s12249-024-02792-z

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Phospholipid Complex Formulation Technology for Improved Drug Delivery in Oncological Settings: a Comprehensive Review

Jayesh Patil, Datta Maroti Pawde, Sankha Bhattacharya & Sauarbh Srivastava

doi : 10.1208/s12249-024-02813-x

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QbD Based Formulation Development and Optimisation of Ozenoxacin Topical Nano-Emulgel and Efficacy Evaluation Using Impetigo Mice Model

Amarnath Reddy Ramireddy & Dilip Kumar Behara

doi : 10.1208/s12249-024-02805-x

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Fluconazole-Loaded Ibuprofen In Situ Gel-Based Oral Spray for Oropharyngeal Candidiasis Treatment

Ei Mon Khaing, Setthapong Senarat, Kritamorn Jitrangsri & Thawatchai Phaechamud

doi : 10.1208/s12249-024-02804-y

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A Comprehensive Analysis of Biopharmaceutical Products Listed in the FDA’s Purple Book

Fuduan Chen, Hao Zhong, Ging Chan & Defang Ouyang

doi : 10.1208/s12249-024-02802-0

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Correction to: Predicting Human Dermal Drug Concentrations Using PBPK Modeling and Simulation: Clobetasol Propionate Case Study

William W. van Osdol, Jasmina Novakovic, Maxime Le Merdy, Eleftheria Tsakalozou, Priyanka Ghosh, Jessica Spires & Viera Lukacova

doi : 10.1208/s12249-024-02795-w

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