JAMA - Journal of the American Medical Association




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Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults

Nawal Al Kaabi, MBBS1; Yuntao Zhang, PhD2; Shengli Xia, BSc3; Yunkai Yang, MSc2; Manaf M. Al Qahtani, MD4; Najiba Abdulrazzaq, MBBS5; Majed Al Nusair, MD6; Mohamed Hassany, MD7; Jaleela S. Jawad, MBBS8; Jehad Abdalla, MBBS1; Salah Eldin Hussein, MBBS1; Shamma K. Al Mazrouei, MBBS1; Maysoon Al Karam, MBBS1; Xinguo Li, MSc9; Xuqin Yang, MSc2; Wei Wang, MSc10; Bonan Lai, MSc2; Wei Chen, MSc9; Shihe Huang, PhD9; Qian Wang, MSc2; Tian Yang, BSc2; Yang Liu, MSc2; Rui Ma, MSc10; Zaidoon M. Hussain, MD1; Tehmina Khan, MD1; Mohammed Saifuddin Fasihuddin, BSc1; Wangyang You, BSc3; Zhiqiang Xie, MSc3; Yuxiu Zhao, MSc10; Zhiwei Jiang, PhD11; Guoqing Zhao, PhD11; Yanbo Zhang, MSc12; Sally Mahmoud, PhD13; Islam ElTantawy, BSc13; Peng Xiao, MSc13; Ashish Koshy, MSc12; Walid Abbas Zaher, PhD13; Hui Wang, BSc10; Kai Duan, PhD9; An Pan, PhD12; Xiaoming Yang, MD2,9

doi : 10.1001/jama.2021.8565

JAMA. 2021;326(1):35-45

Although effective vaccines against COVID-19 have been developed, additional vaccines are still needed.

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Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities

Myron S. Cohen, MD1; Ajay Nirula, MD, PhD2; Mark J. Mulligan, MD3; Richard M. Novak, MD4; Mary Marovich, MD5; Catherine Yen, MD5; Alexander Stemer, MD6; Stockton M. Mayer, DO4; David Wohl, MD1; Blair Brengle, MD7; Brian T. Montague, DO8; Ian Frank, MD9; Russell J. McCulloh, MD10; Carl J. Fichtenbaum, MD11; Brad Lipson, DO12; Nashwa Gabra, MD13; Julio A. Ramirez, MD14; Christine Thai, MD15; Wairimu Chege, MD, MPH5; Margarita M. Gomez Lorenzo, MD5; Nirupama Sista, PhD16; Jennifer Farrior, MS16; Meredith E. Clement, MD17; Elizabeth R. Brown, ScD18; Kenneth L. Custer, PhD2; Jacob Van Naarden, BS2; Andrew C. Adams, PhD2; Andrew E. Schade, MD, PhD2; Matan C. Dabora, MD2; Jack Knorr, PhD2; Karen L. Price, PhD2; Janelle Sabo, PharmD2; Jay L. Tuttle, PhD2; Paul Klekotka, MD, PhD2; Lei Shen, PhD2; Daniel M. Skovronsky, MD, PhD2; for the BLAZE-2 Investigators

doi : 10.1001/jama.2021.8828

JAMA. 2021;326(1):46-55

Preventive interventions are needed to protect residents and staff of skilled nursing and assisted living facilities from COVID-19 during outbreaks in their facilities. Bamlanivimab, a neutralizing monoclonal antibody against SARS-CoV-2, may confer rapid protection from SARS-CoV-2 infection and COVID-19.

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Effect of Cytisine vs Varenicline on Smoking Cessation

Ryan J. Courtney, PhD1; Hayden McRobbie, PhD1; Piotr Tutka, MD2; Natasha A. Weaver, PhD3; Dennis Petrie, PhD4; Colin P. Mendelsohn, MBBS5; Anthony Shakeshaft, PhD1; Saki Talukder, MPH1; Christel Macdonald, BPsych1; Dennis Thomas, PhD6; Benjamin C. H. Kwan, PhD7; Natalie Walker, PhD8; Coral Gartner, PhD9; Richard P. Mattick, PhD1; Christine Paul, PhD3; Stuart G. Ferguson, PhD10; Nicholas A. Zwar, PhD11; Robyn L. Richmond, DSc12; Christopher M. Doran, PhD13; Veronica C. Boland, PhD1; Wayne Hall, PhD14; Robert West, PhD15; Michael Farrell, MB1

doi : 10.1001/jama.2021.7621

JAMA. 2021;326(1):56-64

Cytisine is more effective than placebo and nicotine replacement therapy for smoking cessation. However, cytisine has not been tested against the most effective smoking cessation medication, varenicline, which is associated with adverse events known to lead to discontinuation of therapy.

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Changes in Patterns of Hospital Visits for Acute Myocardial Infarction or Ischemic Stroke During COVID-19 Surges

Matthew D. Solomon, MD, PhD1; Mai Nguyen-Huynh, MD2; Thomas K. Leong, MPH3; Janet Alexander, MSPH3; Jamal S. Rana, MD, PhD1; Jeffrey Klingman, MD2; Alan S. Go, MD3

doi : 10.1001/jama.2021.8414

JAMA. 2021;326(1):82-84

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Mortality From Drug Overdoses, Homicides, Unintentional Injuries, Motor Vehicle Crashes, and Suicides During the Pandemic, March-August 2020

Jeremy S. Faust, MD, MS1; Chengan Du, PhD2; Katherine Dickerson Mayes, MD, PhD3; Shu-Xia Li, PhD4; Zhenqiu Lin, PhD4; Michael L. Barnett, MD, MS5; Harlan M. Krumholz, MD, SM2

doi : 10.1001/jama.2021.8012

JAMA. 2021;326(1):84-86

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COVID-19 Vaccination of Health Care Personnel as a Condition of Employment

Thomas R. Talbot, MD, MPH1

doi : 10.1001/jama.2021.8901

JAMA. 2021;326(1):23-24

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Mandatory SARS-CoV-2 Vaccinations in K-12 Schools, Colleges/Universities, and Businesses

Lawrence O. Gostin, JD1; Jana Shaw, MD, MPH2; Daniel A. Salmon, PhD, MPH3

doi : 10.1001/jama.2021.9342

JAMA. 2021;326(1):25-26

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The American Rescue Plan Act of 2021

Eli Y. Adashi, MD, MS1; I. Glenn Cohen, JD2,3

doi : 10.1001/jama.2021.8389

JAMA. 2021;326(1):27-28

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A Stranger to Silence

Arjun V. K. Sharma, MD1

doi : 10.1001/jama.2021.9896

JAMA. 2021;326(1):29-30

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Bamlanivimab for Prevention of COVID-19

Daniel R. Kuritzkes, MD1

doi : 10.1001/jama.2021.7515

JAMA. 2021;326(1):31-32

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To Howard Bauchner, MD, Visionary Editor in Chief of JAMA—A Sincere Thank You and a Fond Farewell

Phil B. Fontanarosa, MD, MBA1; Annette Flanagin, RN, MA1; for the JAMA and JAMA Network Editors and Editorial Staff

doi : 10.1001/jama.2021.9772

JAMA. 2021;326(1):33-34

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Diagnosis and Management of Infertility

Sandra Ann Carson, MD1; Amanda N. Kallen, MD2

doi : 10.1001/jama.2021.4788

JAMA. 2021;326(1):65-76

In the US, approximately 12.7% of reproductive age women seek treatment for infertility each year. This review summarizes current evidence regarding diagnosis and treatment of infertility.

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Refractive Surgery in the US in 2021

Samir Jabbour, MD, CM1; Kraig S. Bower, MD1

doi : 10.1001/jama.2020.20245

JAMA. 2021;326(1):77-78

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Preconception Care as an Opportunity to Optimize Pregnancy Outcomes

Nandini Raghuraman, MD, MS1; Methodius G. Tuuli, MD, MPH, MBA2,3

doi : 10.1001/jama.2020.27244

JAMA. 2021;326(1):79-80

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Lung Transplants for COVID-19—The Option of Last Resort

Kristin Walter, MD, MS

doi : 10.1001/jama.2021.9363

JAMA. 2021;326(1):14-16

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Ketone Body Supplementation—A Potential New Approach for Heart Disease

Jennifer Abbasi

doi : 10.1001/jama.2021.8789

JAMA. 2021;326(1):17-18

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No Heart Health Effect of Omega-3 Fatty Acids at Highest Plasma Level

Anita Slomski, MA

doi : 10.1001/jama.2021.10482

JAMA. 2021;326(1):19

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Text Message Support Prompts Young Adults to Quit Vaping

Anita Slomski, MA

doi : 10.1001/jama.2021.9398

JAMA. 2021;326(1):19

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Greater Numbers of People in the US Are Living With Vision Loss

Anita Slomski, MA

doi : 10.1001/jama.2021.10483

JAMA. 2021;326(1):19

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Study Estimates Older Adults’ Cancer Deaths After Surgery

Anita Slomski, MA

doi : 10.1001/jama.2021.10484

JAMA. 2021;326(1):19

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New Targeted Non–Small Cell Lung Cancer Therapy Approved

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2021.10550

JAMA. 2021;326(1):20

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FDA Seeks Improvements in Labeling Medical Device Materials

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2021.9842

JAMA. 2021;326(1):20

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FDA, FTC Warn Companies Claiming Their Supplements Treat Infertility

Bridget M. Kuehn, MSJ

doi : 10.1001/jama.2021.10551

JAMA. 2021;326(1):20

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Blame Scheme

Gregory Abel, MD1

doi : 10.1001/jama.2021.7392

JAMA. 2021;326(1):91

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The Cost of Tuberculosis

doi : 10.1001/jama.2020.18014

JAMA. 2021;326(1):92

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Ways to Quit Smoking

Kristin Walter, MD, MS1

doi : 10.1001/jama.2021.7239

JAMA. 2021;326(1):96

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Immune Checkpoint Inhibitor Therapy Toxicities

Heather S. L. Jim, PhD1; Hans Knoop, PhD2; Adam P. Dicker, MD, PhD3

doi : 10.1001/jama.2021.6030

JAMA. 2021;326(1):87

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Immune Checkpoint Inhibitor Therapy Toxicities—Reply

Adam S. Cifu, MD1; Anne R. Bass, MD2; Pankti D. Reid, MD, MPH1

doi : 10.1001/jama.2021.6036

JAMA. 2021;326(1):87-88

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The US Preventive Services Task Force Recommendation Statement About Screening Asymptomatic Adults for Carotid Stenosis

Frank J. Wolters, MD, PhD1; Victor Volovici, MD, PhD2

doi : 10.1001/jama.2021.6495

JAMA. 2021;326(1):88

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The US Preventive Services Task Force Recommendation Statement About Screening Asymptomatic Adults for Carotid Stenosis

Raffaele Ornello, MD1; Francesca Pistoia, MD, PhD1; Simona Sacco, MD1

doi : 10.1001/jama.2021.6487

JAMA. 2021;326(1):89

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The US Preventive Services Task Force Recommendation Statement About Screening Asymptomatic Adults for Carotid Stenosis—Reply

Michael J. Barry, MD1; Karina Davidson, PhD, MASc2; Carol M. Mangione, MD, MSPH3

doi : 10.1001/jama.2021.6492

JAMA. 2021;326(1):89-90

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Errors in Flow Diagram

doi : 10.1001/jama.2021.9465

JAMA. 2021;326(1):90

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Incomplete Financial Disclosure in a Viewpoint

doi : 10.1001/jama.2021.9572

JAMA. 2021;326(1):90

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Addition of Nonauthor Collaborator Names of the French Covid-19 Paediatric Inflammation Consortium

doi : 10.1001/jama.2021.7427

JAMA. 2021;326(1):90

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