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Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging
Sher Bahadur Poudel, Dorra Frikha-Benayed, Ryan R. Ruff, Gozde Yildirim, Manisha Dixit, Ron Korstanje, Laura Robinson, Richard A. Miller, David E. Harrison, John R. Strong, Mitchell B. Schaffler, Shoshana Yakar
doi : 10.18632/aging.205147
Volume 16, Issue 6
Altered brain morphology and functional connectivity in postmenopausal women: automatic segmentation of whole-brain and thalamic subnuclei and resting-state fMRI
Gwang-Won Kim, Kwangsung Park, Yun-Hyeon Kim, Gwang-Woo Jeong
doi : 10.18632/aging.205662
CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction
Alcir L. Dafre, Saadia Zahid, Jessica Jorge Probst, Antonio Currais, Jingting Yu, David Schubert, Pamela Maher
doi : 10.18632/aging.205673
Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model
Peramaiyan Rajendran, Fatma J. Al-Saeedi, Rebai Ben Ammar, Basem M. Abdallah, Enas M. Ali, Najla Khaled Al Abdulsalam, Sujatha Tejavat, Duaa Althumairy, Vishnu Priya Veeraraghavan, Sarah Abdulaziz Alamer, Gamal M. Bekhet, Emad A. Ahmed
doi : 10.18632/aging.205677
Phoenixin 20 ameliorates pulmonary arterial hypertension via inhibiting inflammation and oxidative stress
Yaqin Chai, Xing Gu, HongJun Zhang, Xinting Xu, Lizhan Chen
doi : 10.18632/aging.205468
The protective effects of Arctiin in asthma by attenuating airway inflammation and inhibiting p38/NF-κB signaling
Lang Yuan, Chao Sun
doi : 10.18632/aging.205584
Omilancor mitigates the senescence of nucleus pulposus cells induced by DDP through targeting MAP2K6
Fang Yafeng, Shi Xinpeng, Wei Rong, Cui Guofeng
doi : 10.18632/aging.205588
The protective effects of Irbesartan in cognitive impairment in hypertension
Shengyun Hao, Qian He, Yuan Yuan, Qiong Mu
doi : 10.18632/aging.205589
FOXQ1 inhibits the progression of osteoarthritis by regulating pyroptosis
Zhihuan Luo, Hui Zeng, Kanghua Yang, Yihai Wang
doi : 10.18632/aging.205600
GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway
Fenghua Zhang, Chiming Huang
doi : 10.18632/aging.205605
Portulaca oleracea L. polysaccharide inhibits ovarian cancer via inducing ACSL4-dependent ferroptosis
Liping Xia, Mo Yang, Yan Liu
doi : 10.18632/aging.205608
The comprehensive landscape of prognosis, immunity, and function of the GLI family by pan-cancer and single-cell analysis
Yinteng Wu, Wenliang Guo, Tao Wang, Ying Liu, Marìa del Mar Requena Mullor, Raquel Alarcòn Rodrìguez, Shijian Zhao, Ruqiong Wei
doi : 10.18632/aging.205630
A novel immune-related lncRNA signature predicts the prognosis and immune landscape in ccRCC
Longlong Dai, Daen Pan, Jiafei Jin, Wenhui Lv
doi : 10.18632/aging.205633
Novel histone acetylation-related lncRNA signature for predicting prognosis and tumor microenvironment in esophageal carcinoma
Batter Han, Ying Ma, Pengjie Yang, Fangchao Zhao, Haiyong Zhu, Shujun Li, Rong Yu, Subudao Bao
doi : 10.18632/aging.205636
BMSCs-derived exosomes inhibit macrophage/microglia pyroptosis by increasing autophagy through the miR-21a-5p/PELI1 axis in spinal cord injury
Jun Gu, Jingyi Wu, Chunming Wang, Zhenwei Xu, Zhengshuai Jin, Donghua Yan, Sheng Chen
doi : 10.18632/aging.205638
Allicin treats myocardial infarction in I/R through the promotion of the SHP2 axis to inhibit p-PERK-mediated oxidative stress
Tong Gao, Mengru Liu, Dongliang Fu, Yajun Xue, Jiangquan Liao, Peng Yang, Xianlun Li
doi : 10.18632/aging.205640
Development and validation of a novel biomarker panel for Crohn’s disease and rheumatoid arthritis diagnosis and treatment
Hao Zhang, Wenhao Qiao, Ran Liu, Zuoxiu Shi, Jie Sun, Shuxiao Dong
doi : 10.18632/aging.205644
Molecular characterization of Golgi apparatus-related genes indicates prognosis and immune infiltration in osteosarcoma
Jian Zhang, Jiahao Liu, Rui Ding, Xinxin Miao, Jianjian Deng, Xiaokun Zhao, Tianlong Wu, Xigao Cheng
doi : 10.18632/aging.205645
COP9 signalosome complex is a prognostic biomarker and corresponds with immune infiltration in hepatocellular carcinoma
Jiahui Liu, Dexing Han, Junfeng Xuan, Jinye Xie, Weijia Wang, Quan Zhou, Kang Chen
doi : 10.18632/aging.205646
Comprehensive assessment of regulatory T-cells-related scoring system for predicting the prognosis, immune microenvironment and therapeutic response in hepatocellular carcinoma
Bitao Jiang, Xiaojuan Ye, Wenjuan Wang, Jiajia He, Shuyan Zhang, Song Zhang, Lingling Bao, Xin Xu
doi : 10.18632/aging.205649
Construction of an oxidative phosphorylation-related gene signature for predicting prognosis and identifying immune infiltration in osteosarcoma
Peng Zhou, Jin Zhang, Jinyan Feng, Guowen Wang
doi : 10.18632/aging.205650
Antagomir of miR-31-5p modulates macrophage polarization via the AMPK/SIRT1/NLRP3 signaling pathway to protect against DSS-induced colitis in mice
Yuyi Yuan, Shuangjiao Deng, Jia Yang, Zhexing Shou, Chunzhu Wei, Lijuan Zhang, Feng Zhu, Fei Gao, Xingxing Liu, Yujin Liu, Qianyun Chen, Heng Fan
doi : 10.18632/aging.205651
Cancer cachexia reduces the efficacy of immune checkpoint inhibitors in cancer patients
Yean Yu, Li Yan, Tianhui Huang, Zhenfu Wu, Juan Liu
doi : 10.18632/aging.205652
Comprehensive analysis of gene expression profiles of annulus fibrosus subtypes and hub genes in intervertebral disc degeneration
Xiaokun Zhao, Jian Zhang, Jiahao Liu, Jinghong Yuan, Tianlong Wu, Xigao Cheng
doi : 10.18632/aging.205653
Network pharmacology and experimental evaluation strategies to decipher the underlying pharmacological mechanism of Traditional Chinese Medicine CFF-1 against prostate cancer
Yong Wei, Mingxia Zhu, Ye Chen, Qianying Ji, Jun Wang, Luming Shen, Xin Yang, Haibin Hu, Xin Zhou, Qingyi Zhu
doi : 10.18632/aging.205654
A comprehensive investigation on the receptor BSG expression reveals the potential risk of healthy individuals and cancer patients to 2019-nCoV infection
Yongbiao Huang, Haiting Zhou, Yuan Wang, Lingyan Xiao, Wan Qin, Long Li
doi : 10.18632/aging.205655
Identification of key lncRNAs in age-related macular degeneration through integrated bioinformatics and experimental validation
Yuying Ji, Chengguo Zuo, Nanying Liao, Liwei Yao, Ruijun Yang, Hui Chen, Feng Wen
doi : 10.18632/aging.205656
Cyclocarya paliurus leaves alleviate high-sucrose diet-induced obesity by improving intestinal metabolic disorders
Ye Yao, Xiaojuan Wang, Dongyu Li, Shujuan Chen, Chengjie Li, Haiyu Guan, Dongsheng Wang, Xiaoli Nie
doi : 10.18632/aging.205657
Integrated single-cell sequencing, spatial transcriptome sequencing and bulk RNA sequencing highlights the molecular characteristics of parthanatos in gastric cancer
Xiuli Qiao, Jiaao Sun, Pingping Ren, Hui Guo, Hua Xu, Chongchan Bao, Chunmeng Jiang
doi : 10.18632/aging.205658
Structural insights into human EMC and its interaction with VDAC
Mingyue Li, Chunli Zhang, Yuntao Xu, Shaobai Li, Chenhui Huang, Jian Wu, Ming Lei
doi : 10.18632/aging.205660
Cinobufotalin regulates the USP36/c-Myc axis to suppress malignant phenotypes of colon cancer cells in vitro and in vivo
Yongjun Hu, Ming Luo
doi : 10.18632/aging.205661
A pyrimidine metabolism-related signature for prognostic and immunotherapeutic response prediction in hepatocellular carcinoma by integrating analyses
Shihang Zhang, Ouyang Qin, Shu Wu, Huanming Xu, Wei Huang, Song Hailiang
doi : 10.18632/aging.205663
CRIF1 attenuates doxorubicin-mediated mitochondrial dysfunction and myocardial senescence via regulating PXDN
Lina Zhou, Guilan Zhai, Ge Tian
doi : 10.18632/aging.205664
Correlation between S100A7 and immune characteristics, methylation, tumor stemness and tumor heterogeneity in pan-cancer and its role in chemotherapy resistance in breast cancer
Yilun Li, Xiaolu Yang, Tingting Jin, Qiuli Li, Xiaolong Li, Li Ma
doi : 10.18632/aging.205665
WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma
Qiankun Ji, Yazhou Guo, Zibo Li, Xiaoyang Zhang
doi : 10.18632/aging.205666
Predicting the prognosis of glioma patients with TERT promoter mutations and guiding the specific immune profile of immune checkpoint blockade therapy
Wenpeng Cao, Jinzhi Lan, Chujiao Hu, Jinping Kong, Limin Xiang, Zhixue Zhang, Yating Sun, Zhirui Zeng, Shan Lei
doi : 10.18632/aging.205668
Identification and validation of ferroptosis-related gene SLC2A1 as a novel prognostic biomarker in AKI
Huaying Wang, Yuanyuan Li, Xinran Liu, Yonggui Wu
doi : 10.18632/aging.205669
Single cell RNA-seq identifies a FOS/JUN-related monocyte signature associated with clinical response of heart failure patients with mesenchymal stem cell therapy
Hui Yuan, Pengfei Zhang, Yuanfeng Xin, Zhongmin Liu, Bingren Gao
doi : 10.18632/aging.205670
Identification and validation of a novel signature based on macrophage marker genes for predicting prognosis and drug response in kidney renal clear cell carcinoma by integrated analysis of single cell and bulk RNA sequencing
Xiaoxu Chen, Zheyu Zhang, Zheng Qin, Xiao Zhu, Kaibin Wang, Lijuan Kang, Changying Li, Haitao Wang
doi : 10.18632/aging.205671
M1 intestinal macrophages-derived exosomes promote colitis progression and mucosal barrier injury
Rui Du, Sihan Chen, Chenyang Han, Zhongmei He, Hongyan Pei, Yang Yang
doi : 10.18632/aging.205672
Relationship between fatty acid intake and aging: a Mendelian randomization study
Yuhua Chen, Lian Yang, Kui Wang, Yu An, Yuping Wang, Ya Zheng, Yongning Zhou
doi : 10.18632/aging.205674
Evaluation of the clinical significance of long non-coding RNAÂ MALAT1Â genetic variants in human lung adenocarcinoma
Shu-Hui Lin, Jeng-Wei Lu, Wang-Ting Hsieh, Ying-Erh Chou, Tzu-Cheng Su, Tun-Jen Tsai, Yun-Jung Tsai, Po-Jen Yang, Shun-Fa Yang
doi : 10.18632/aging.205675
Comprehensive analysis of scRNA-seq and bulk RNA-seq reveal the characteristics of disulfidptosis and a prognostic signature in BLCA
Hao Deng, Fan Cheng, Shaoping Cheng
doi : 10.18632/aging.205686
Considering the response in addition to the challenge – a narrative review in appraisal of a motor reserve framework
Daniel Zeller, Shawn Hiew, Thorsten Odorfer, Carine Nguemeni
doi : 10.18632/aging.205667
Correction for: Apremilast ameliorates IL-1α-induced dysfunction in epidermal stem cells
Yuxi Jia, Xiangru Chen, Jing Sun
doi : 10.18632/aging.205318
Correction for: KIFC1 promotes proliferation and pseudo-bipolar division of ESCC through the transportation of Aurora B kinase
Bin Du, Lingyu Wei, Jia Wang, Yanyan Li, Jing Huo, Jinsheng Wang, Pu Wang
doi : 10.18632/aging.205719
