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Genome-wide transcriptome profiling and development of age prediction models in the human brain
Joseph A. Zarrella, Amy Tsurumi
doi : 10.18632/aging.205609
Volume 16, Issue 5
FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet
Dae Hyun Kim, Seulah Lee, Sang Gyun Noh, Jaewon Lee, Hae Young Chung
doi : 10.18632/aging.205610
PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation
Chitra Palanivel, Lepakshe S. V. Madduri, Ashley L. Hein, Christopher B. Jenkins, Brendan T. Graff, Alison L. Camero, Sumin Zhou, Charles A. Enke, Michel M. Ouellette, Ying Yan
doi : 10.18632/aging.205619
Azilsartan improves urinary albumin excretion in hypertension mice
Jun Cao, Dandan Zhang, Wenfeng Li, Wenjin Yuan, Gang Luo, Shaofeng Xie
doi : 10.18632/aging.205271
Complementary biomarkers of computed tomography for diagnostic grading of gastric cancer: DSCC1 and GINS1
Yufeng Zhu, Shiyang Hou, Chunbo Kang
doi : 10.18632/aging.205491
RAB22A as a predictor of exosome secretion in the progression and relapse of multiple myeloma
Bingjie Fan, Li Wang, Jishi Wang
doi : 10.18632/aging.205565
Calycosin (CA) inhibits proliferation, migration and invasion by suppression of CXCL10 signaling pathway in glioma
Xiaoyu Zheng, Danmin Chen, Menghui Li, Jianchen Liao, Liqun He, Lu Chen, Rong Xu, Maoying Zhang
doi : 10.18632/aging.205572
The crucial role of age and site in incidence and prognosis of female neuroendocrine neoplasms in the United States: a population-based study from 2000 to 2018
Guixiu Xiao, Zihan Xu, Yong Zhang, Shuang Dai, Ganlu Ouyang, Yan Huang, Yanyang Liu, Dan Cao, Feng Luo
doi : 10.18632/aging.205573
The effect of STAT1, miR-99b, and MAP2K1 in alcoholic liver disease (ALD) mouse model and hepatocyte
Hongbo Du, Hao Yu, Meiyue Zhou, Quan Hui, Yixin Hou, Yuyong Jiang
doi : 10.18632/aging.205579
AST-120 improved uremic pruritus by lowering indoxyl sulfate and inflammatory cytokines in hemodialysis patients
Chia-Chao Wu, Ya-Chung Tian, Chien-Lin Lu, Ming-Ju Wu, Paik-Seong Lim, Yi-Wen Chiu, Ko-Lin Kuo, Shou-Hsuan Liu, Yu-Ching Chou, Chien-An Sun, Yi-Chou Hou, Kuo-Cheng Lu
doi : 10.18632/aging.205580
Lei’s formula attenuates osteoarthritis mediated by suppression of chondrocyte senescence via the mTOR axis: in vitro and in vivo experiments
Xing Zhou, Wen-Kai Li, Chen Zhuang, Xing-Chen Zhou, Xue-Fei Zhao, Yu Pan, Wen-Xuan Guo, Yi-Wen Yang, Cen-Zhuo Sheng, Zhe-Fei Xie, Jin-Sheng Yu, Yi-Xuan Chen, Li-Kang Wang, Tian-You Ma, Kang-Xiang Zhu, Ke-Meng Xiang, Ru-Jie Zhuang
doi : 10.18632/aging.205582
Genetically predicted telomere length and the risk of 11 hematological diseases: a Mendelian randomization study
Yimin Wang, Qi Liu, Shibing Liang, Minghao Yao, Huimin Zheng, Dongqing Hu, Yifei Wang
doi : 10.18632/aging.205583
GABA in the anterior cingulate cortex mediates the association of white matter hyperintensities with executive function: a magnetic resonance spectroscopy study
Xiaona Fu, Peng Sun, Xinli Zhang, Dongyong Zhu, Qian Qin, Jue Lu, Jing Wang
doi : 10.18632/aging.205585
The tsRNAs (tRFdb-3013a/b) serve as novel biomarkers for colon adenocarcinomas
Lihong Tan, Xiaoling Wu, Zhurong Tang, Huan Chen, Weiguo Cao, Chunjie Wen, Guojun Zou, Hecun Zou
doi : 10.18632/aging.205590
4-Hydroxyphenylpyruvate Dioxygenase-Like predicts the prognosis and the immunotherapy response of cancers: a pan-cancer analysis
Huimin Li, Junzhi Liu, Shurui Wang, Yue Xu, Qiang Tang, Guoguang Ying
doi : 10.18632/aging.205591
Prenatal diesel exhaust exposure alters hippocampal synaptic plasticity in offspring
Shali Yu, Ziyang Zhang, Ziyu Qin, Meijun Liu, Xiaoye Zhao, Yulan Cheng, Peng Xue, Xiaoke Wang, Lin Chen, Qiyun Wu, Linling Ju, Juan Tang
doi : 10.18632/aging.205592
Probucol protects against brain damage caused by intra-neural pyroptosis in rats with vascular dementia through inhibition of the Syk/Ros pathway
Jingyi Zhu, Jing Du, Wenhui Kou, Chenling Liu, Jianchun Fan, Ziyan Zhu, Lexiu Deng, Lingling Guan, Yuandi Wang, Aimei Yu
doi : 10.18632/aging.205593
The prognosis, chemotherapy and immunotherapy efficacy of the SUMOylation pathway signature and the role of UBA2 in lung adenocarcinoma
Liying Yu, Na Lin, Yan Ye, Haohan Zhuang, Shumei Zou, Yingfang Song, Xiaoli Chen, Qingshui Wang
doi : 10.18632/aging.205594
A pair of primary colorectal cancer-derived and corresponding synchronous liver metastasis-derived organoid cell lines
Fangling Cheng, Pengcheng Li, Sanpeng Xu, Chao Zhang, Huifang Liang, Zeyang Ding
doi : 10.18632/aging.205595
SLC20A1 is a prospective prognostic and therapy response predictive biomarker in head and neck squamous cell carcinoma
Xiajing Qian, Ming Jin, Yanping Bei, Chongchang Zhou, Shuai Fang, Kaitai Liu
doi : 10.18632/aging.205597
Comprehensive characterization of Fidgetin on tumor immune microenvironment evaluation and immunotherapy in human hepatocellular carcinoma
Longju Qi, Shiyuan Chen, Zehua Liao, Mengjie Fan, Jiayi Zhang, Yuan Gao, Jiabao Shen, Yuyu Sun, Qinghua Wang
doi : 10.18632/aging.205598
Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene MXRA8
Miao Miao, Yan Song, Mingyue Jin, Yang Du, Peng Xin, Yuanjun Jiang, Hao Zhang
doi : 10.18632/aging.205599
Exploration of the utility of different doses of Qingfei Dayuan granules: a multicenter, randomized, double-blind, placebo-controlled trial
Xiaoyun Zhu, Weinan Li, Yi Yang, Hengfei Li, Min Yang, Jilong Zhang, Xucheng Li, Guangjun Yan, Xiongfei Wu, Weijun Zhao, Mengdi Cui, Xi Yang, Xinyu Hu, Juan Huang, Yuanming Ba
doi : 10.18632/aging.205601
Tumor-infiltrating macrophage associated lncRNA signature in cutaneous melanoma: implications for diagnosis, prognosis, and immunotherapy
Qi Wan, Yuhua Deng, Ran Wei, Ke Ma, Jing Tang, Ying-Ping Deng
doi : 10.18632/aging.205606
Ningxin-Tongyu-Zishen formula alleviates the senescence of granulosa cells on D-galactose-induced premature ovarian insufficiency mice
Jia-Wen Ma, Zeng-Yan Xiong, Xing-Chu Cai, Xiang Li, Shi-Yan Ren, Shuai-Qi An, Zai-Yang Zhang, Yi-Zhou Zhang
doi : 10.18632/aging.205607
Machine learning-based endoplasmic reticulum-related diagnostic biomarker and immune microenvironment landscape for osteoarthritis
Tingting Liu, Xiaomao Li, Mu Pang, Lifen Wang, Ye Li, Xizhe Sun
doi : 10.18632/aging.205611
A novel classification predicts prognosis and drug sensitivity in osteosarcoma based on alterations in gene sets
Shuxi Ye, Xiaopeng Wang, Rongchun Chen
doi : 10.18632/aging.205614
GBA3 promotes fatty acid oxidation and alleviates non-alcoholic fatty liver by increasing CPT2 transcription
Juyi Li, Yingqun Ni, Yuanyuan Zhang, Huaizhen Liu
doi : 10.18632/aging.205616
Myogenic exosome miR-140-5p modulates skeletal muscle regeneration and injury repair by regulating muscle satellite cells
Xiaorui Cao, Linli Xue, Xiuju Yu, Yi Yan, Jiayin Lu, Xiaomao Luo, Haidong Wang, Juan Wang
doi : 10.18632/aging.205617
miR-26a-5p inhibits the proliferation of psoriasis-like keratinocytes in vitro and in vivo by dual interference with the CDC6/CCNE1 axis
Jianing Li, Daxin Pang, Lin Zhou, Hongsheng Ouyang, Yaping Tian, Hao Yu
doi : 10.18632/aging.205618
Explainable machine learning in outcome prediction of high-grade aneurysmal subarachnoid hemorrhage
Lei Shu, Hua Yan, Yanze Wu, Tengfeng Yan, Li Yang, Si Zhang, Zhihao Chen, Qiuye Liao, Lu Yang, Bing Xiao, Minhua Ye, Shigang Lv, Miaojing Wu, Xingen Zhu, Ping Hu
doi : 10.18632/aging.205621
Echinatin mitigates sevoflurane-induced neurotoxicity through regulation of ferroptosis and iron homeostasis
Yanqiu You, Xudong Zhou, Qiuqin Tang, Tianshou Zhao, Juan Wang, Hanqin Huang, Jibing Chen, Zhongquan Qi, Fujun Li
doi : 10.18632/aging.205622
Genetically determined telomere length as a risk factor for hematological malignancies: evidence from Mendelian randomization analysis
Tian Fang, Zhihao Zhang, Kexing Ren, Liqun Zou
doi : 10.18632/aging.205625
SUMF1 overexpression promotes tumorous cell growth and migration and is correlated with the immune status of patients with glioma
Ping Zhang, Zhao Liu, Yu-Yu Wang, Hui-Jiu Luo, Chao-Zhi Yang, Hao Shen, Hai-Tao Wu, Ju-Hang Li, Hong-Xin Zhao, Qi-Shan Ran
doi : 10.18632/aging.205626
A Mendelian randomization analysis identifies causal association between sarcopenia and gastroesophageal reflux disease
Renwang Hu, Can Liu, Dan Li
doi : 10.18632/aging.205627
Investigating the mechanisms of drug resistance and prognosis in ovarian cancer using single-cell RNA sequencing and bulk RNA sequencing
Pengfei Liu, Jinbao Liu, Jinxing Liu, Xiao Yu
doi : 10.18632/aging.205628
Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition
Lu Han, Guoyuan Lin, Jianchao Li, Qingxiu Zhang, Tao Ran, Tao Huang, Ruihan Hu, Shu Feng, Gaoliang Zou, Shaojie Chen, Xueke Zhao
doi : 10.18632/aging.205629
The low expression of miR-155 promotes the expression of SHP2 by inhibiting the activation of the ERK1/2 pathway and improves cell pyroptosis induced by I/R in mice
Mengru Liu, Dongliang Fu, Tong Gao, Hong Jiang, Peng Yang, Xianlun Li
doi : 10.18632/aging.205631
SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization
Kai Feng, Ya Di, Meng Han, Weitao Yan, Yimin Wang
doi : 10.18632/aging.205632
FHND004 inhibits malignant proliferation of multiple myeloma by targeting PDZ-binding kinase in MAPK pathway
Hongjie Wu, Jinjun Qian, Lianxin Zhou, Tingting Hu, Yuanjiao Zhang, Chen Wang, Ye Yang, Chunyan Gu
doi : 10.18632/aging.205634
Chlorogenic acid prevents ovariectomized-induced bone loss by facilitating osteoblast functions and suppressing osteoclast formation
Chien-Yi Ho, Chih-Hsin Tang, Trung-Loc Ho, Wen-Ling Wang, Chun-Hsu Yao
doi : 10.18632/aging.205635
HOXC9 characterizes a suppressive tumor immune microenvironment and integration with multiple immune biomarkers predicts response to PD-1 blockade plus chemotherapy in lung adenocarcinoma
Liang Liu, Zhenshan Zhang, Chenxue Jiang, Yaoyao Zhu, Ruiqin Han, Leilei Wu, Yaping Xu
doi : 10.18632/aging.205637
Molecular characteristics and prognostic significances of lysosomal-dependent cell death in kidney renal clear cell carcinoma
Shunliang He, Jiaao Sun, Hewen Guan, Ji Su, Xu Chen, Zhijun Hong, Jianbo Wang
doi : 10.18632/aging.205639
5-Hydroxytryptophan acts as a gap junction inhibitor to limit the spread of chemotherapy-induced cardiomyocyte injury and mitochondrial dysfunction
Wenshe Sun, Qi Lu, Yukun Zhang, Dongming Xing
doi : 10.18632/aging.205641
MicroRNA-18a prevents senescence of mesenchymal stem cells by targeting CTDSPL
Bo Sun, Xian-Hui Meng, Yu-Min Li, Hao Lin, Zhong-Dang Xiao
doi : 10.18632/aging.205642
Establishment of an immunogenic cell death-related model for prognostic prediction and identification of therapeutic targets in endometrial carcinoma
Zhenran Liu, Yue Huang, Pin Zhang, Chen Yang, Yujie Wang, Yaru Yu, Huifen Xiang
doi : 10.18632/aging.205647
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial
Kara N. Fitzgerald, Romilly Hodges, Douglas Hanes, Emily Stack, David Cheishvili, Moshe Szyf, Janine Henkel, Melissa W. Twedt, Despina Giannopoulou, Josette Herdell, Sally Logan, Ryan Bradley
doi : 10.18632/aging.205700
Retraction: Silencing lncRNA XIST exhibits antiproliferative and proapoptotic effects on gastric cancer cells by up-regulating microRNA-132 and down-regulating PXN
Ping Li, Liuhua Wang, Pengfei Li, Fangyong Hu, Yi Cao, Dong Tang, Gang Ye, Hongbo Li, Daorong Wang
doi : 10.18632/aging.205702
