Neurology




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Comparative Effectiveness of Natalizumab, Fingolimod, and Injectable Therapies in Pediatric-Onset Multiple Sclerosis: A Registry-Based Study.

Spelman, Tim PhD, MBBS, BSc; Simoneau, Gabrielle PhD, MSci, BSc; Hyde, Robert PhD, BSc; Kuhelj, Robert PhD; Alroughani, Raed MD; Ozakbas, Serkan MD; Karabudak, Rana MD; Yamout, Bassem I. MD; Khoury, Samia J. MD; Terzi, Murat MD; Boz, Cavit MD; Horakova, Dana MD, PhD; Kubala Havrdova, Eva MD, PhD; Weinstock-Guttman, Bianca MD; Patti, Francesco MD; Altintas, Ayse MD; Mrabet, Saloua MD; Gouider, Riadh MD; Inshasi, Jihad MD; Shaygannejad, Vahid PhD; Eichau, Sara MD, PhD; Ward, W. Luke BCS; Butzkueven, Helmut MBBS, PhD; for the MSBase Investigators

doi : 10.1212/WNL.0000000000208114

Volume 102(7) pgs. e208114-e209253 April 9, 2024

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Association of Glycemic Variability With Imaging Markers of Vascular Burden, [beta]-Amyloid, Brain Atrophy, and Cognitive Impairment.

doi : 10.1212/WNL.0000000000209274

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MOG Antibodies Restricted to CSF in Children With Inflammatory CNS Disorders.

Olive-Cirera, Gemma MD *; Bruijstens, Arlette L. MD, PhD *; Fonseca, Elianet G. MD; Chen, Li-Wen MD, PhD; Caballero, Eva BS; Martinez-Hernandez, Eugenia MD, PhD; Guasp, Mar MD, PhD; Sepulveda, Maria MD, PhD; Naranjo, Laura PhD; Ruiz-Garcia, Raquel PhD; Blanco, Yolanda MD, PhD; Saiz, Albert MD, PhD; Dalmau, Josep O. MD, PhD; Armangue, Thais MD, PhD; for the Spanish Pediatric MOGAD Study Group

doi : 10.1212/WNL.0000000000209199

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Trans-Synaptic Degeneration in the Visual Pathway in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.

Bollo, Luca MD; Arrambide, Georgina MD, PhD; Cobo-Calvo, Alvaro MD, PhD; Alvarez, Javier V. MD; Alberich, Manel; Cabello, Sergio MD; Castillo, Joaquin MD; Galan, Ingrid MD; Midaglia, Luciana S. MD; Acevedo, Breogan Rodriguez MD; Zabalza, Ana; Pappolla, Agustin MD, MSc; Mongay Ochoa, Neus MD; Tintore, Mar MD; Rio, Jordi MD, PhD; Comabella, Manuel; Tur, Carmen MD, PhD; Auger, Cristina MD, PhD; Sastre-Garriga, Jaume MS, PhD; Rovira, Alex; Montalban, Xavier MD, PhD; Pareto, Deborah PhD; Vidal-Jordana, Angela MD, PhD

doi : 10.1212/WNL.0000000000209156

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The Visual System in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: Beyond the Optic Nerve.

Collorone, Sara PhD; Toosy, Ahmed T. FRCP

doi : 10.1212/WNL.0000000000209209

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Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults.

Rajan, Kumar B. PhD; Mcaninch, Elizabeth A. MD; Wilson, Robert S. PhD; Dhana, Anisa MD; Evans-Lacko, Sara PhD; Evans, Denis A. PhD

doi : 10.1212/WNL.0000000000209168

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Trends in Cognitive Function Before and After Diabetes Onset: The China Health and Retirement Longitudinal Study.

Chen, Qingmei MD *; Zhu, Sijia MD *; Shang, Jing MD, PhD; Fang, Qi MD, PhD; Xue, Qun MD, PhD; Hua, Jianian MD

doi : 10.1212/WNL.0000000000209165

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Identifying Modifiable Determinants of Cognitive Decline and Dementia Risk: The Power of Evidence From Diverse Contexts.

Mayeda, Elizabeth Rose PhD, MPH; Wu, Yingyan MS

doi : 10.1212/WNL.0000000000209293

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Development of a Composite Score for the Clinical Assessment of Anti-IgLON5 Disease.

Gaig, Carles MD, PhD; Gruter, Thomas MD; Heidbreder, Anna MD; Sabater, Lidia PhD; Iranzo, Alex MD, PhD; Santamaria, Joan MD, PhD; Leypoldt, Frank MD; Dalmau, Josep O. MD, PhD; Ayzenberg, Ilya MD; Graus, Francesc MD, PhD

doi : 10.1212/WNL.0000000000208101

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Redefining Patient Evaluation in Anti-IgLON5 Disease: Anti-IgLON5 Disease Composite Score.

Thakolwiboon, Smathorn MD; Dubey, Divyanshu MD

doi : 10.1212/WNL.0000000000209213

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Remote Ischemic Conditioning With Medical Management or Reperfusion Therapy for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.

Li, Qi MS *; Guo, Jinxiu MS *; Chen, Hui-sheng MD PhD; Blauenfeldt, Rolf Ankerlund MD; Hess, David C. MD; Pico, Fernando MD; Khatri, Pooja MD, MSc; Campbell, Bruce C.V. PhD; Feng, Xinggang MS; Abdalkader, Mohamad MD; Saver, Jeffrey L. MD; Nogueira, Raul G. MD; Jiang, Bingwu MS; Li, Bing MS; Yang, Min MS; Sang, Hongfei MD; Yang, Qingwu MD; Qiu, Zhongming MD; Dai, Yi MS +; Nguyen, Thanh N. MD +

doi :  10.1212/WNL.0000000000207983

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Remote Ischemic Conditioning for Secondary Stroke Prevention: Time for a Clinical Trial?.

Nadareishvili, Zurab MD, PhD; Bath, Philip M. FRCP, DSc, FMedSci; England, Timothy J. MBChB, PhD, FRCP

doi : 10.1212/WNL.0000000000208072

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Teaching Video NeuroImage: Rabbit Syndrome.

Huynh, Thuy-Uyen MD; Beckley, Ethan H. MD, PhD

doi : 10.1212/WNL.0000000000209275

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Statin Therapy for Secondary Prevention in Ischemic Stroke Patients With Cerebral Microbleeds.

Prats-Sanchez, Luis MD, PhD *; Camps-Renom, Pol MD, PhD *; Nash, Philip S. MD; Wilson, Duncan MD, PhD; Ambler, Gareth PhD; Best, Jonathan G. MD; Guasch-Jimenez, Marina MD; Ramos-Pachon, Anna; Martinez-Domeno, Alejandro MD; Lambea-Gil, Alvaro MD; Diaz, Garbine Ezcurra MD; Guisado-Alonso, Daniel MD, PhD; Du, Houwei MD; Al-Shahi Salman, Rustam PhD; Jager, Hans Rolf MD; Lip, Gregory Y. MD; Ay, Hakan MD; Jung, Simon MD; Bornstein, Natan M. MD; Gattringer, Thomas MD, PhD; Eppinger, Sebastian MD; van Dam-Nolen, Dianne H. MD; Koga, Masatoshi MD, PhD; Toyoda, Kazunori MD, PhD; Fluri, Felix MD; Phan, Thanh G. FRACP; Srikanth, Velandai K. PhD; Heo, Ji Hoe MD; Bae, Hee-Joon MD, PhD; Kelly, Peter J. MD, MS, FRCPI, ABPN (Dip); Imaizumi, Toshio MD, PhD; Staals, Julie MD, PhD; Kohler, Sebastian PhD; Yakushiji, Yusuke MD, PhD; Orken, Dilek Necioglu MD; Smith, Eric E. MD, MPH; Wardlaw, Joanna M. MD, FRCR; Chappell, Francesca M. PhD; Makin, Stephen D. MBChB, PhD; Mas, Jean-Louis MD; Calvet, David MD, PhD; Bordet, Regis MD; Chen, Christopher P. MD; Veltkamp, Roland MD; Kandiah, Nagaendran MD; Simister, Robert J. PhD; De Leeuw, Frank-Erik MD; Engelter, Stefan T. MD; Peters, Nils MD; Soo, Yannie O. MD, ChB; Zietz, Annaelle MMed; Hendrikse, Jeroen MD, PhD; Mess, Werner H. MD, PhD; Werring, David J. PhD; Marti-Fabregas, Joan MD, PhD; for the Microbleeds International Collaborative Network (MICON)

doi : 10.1212/WNL.0000000000209173

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Efficacy and Safety of Statins for Secondary Stroke Prevention in Patients With Cerebral Microbleeds: Jury Is Still Out.

Nadareishvili, Zurab MD, PhD; Katsanos, Aristeidis H. MD, PhD; Shoamanesh, Ashkan MD, FRCPC

doi : 10.1212/WNL.0000000000209261

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Association of Neurotrophic Factors at Midlife With In Vivo Measures of [beta]-Amyloid and Tau Burden 15 Years Later in Dementia-Free Adults.

Weinstein, Galit PhD; Kojis, Daniel J. BA; Ghosh, Saptaparni PhD; Beiser, Alexa S. PhD; Seshadri, Sudha MD

doi : 10.1212/WNL.0000000000209198

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Identification of Distinct Brain MRI Phenotypes and Their Association With Long-Term Dementia Risk in Community-Dwelling Older Adults.

Keller, Jasmin Annica MSc; Sigurdsson, Sigurdur MSc, PhD; Schmitz Abecassis, Barbara MSc; Kant, Ilse M.J. MSc, PhD; Van Buchem, Mark A. MD, PhD; Launer, Lenore J. PhD; van Osch, Matthias J.P. PhD; Gudnason, Vilmundur MD, PhD; de Bresser, Jeroen MD, PhD

doi : 10.1212/WNL.0000000000209176

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Nonalcoholic Fatty Liver Disease and Longitudinal Change in Imaging and Plasma Biomarkers of Alzheimer Disease and Vascular Pathology.

Lu, Yifei PhD; Pike, James R. MBA; Hoogeveen, Ron PhD; Walker, Keenan PhD; Raffield, Laura PhD; Selvin, Elizabeth PhD, MPH; Avery, Christy PhD; Engel, Stephanie PhD; Mielke, Michelle M. PhD; Garcia, Tanya PhD; Heiss, Gerardo PhD; Palta, Priya PhD, MHS

doi : 10.1212/WNL.0000000000209203

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Association of Age-Related Neuropathologic Findings at Autopsy With a Claims-Based Epilepsy Diagnosis in Older Adults.

Oveisgharan, Shahram MD; Grodstein, Francine ScD; Evia, Arnold M. Jr PhD; James, Bryan D. PhD; Capuano, Ana W. MPS, MS, PhD; Chen, Yi PhD; Arfanakis, Konstantinos PhD; Schneider, Julie A. MD; Bennett, David A. MD

doi : 10.1212/WNL.0000000000209172

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Electrographic Status Epilepticus Terminated by Acute Thalamic Stimulation.

Tobochnik, Steven MD; Ellaithy, Amr MD, PhD; Rolston, John D. MD, PhD

doi : 10.1212/WNL.0000000000209229

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Editors' Note: Association of Alternative Anticoagulation Strategies and Outcomes in Patients With Ischemic Stroke While Taking a Direct Oral Anticoagulant.

Ganesh, Aravind MD, DPhil, FRCPC; Galetta, Steven MD

doi : 10.1212/WNL.0000000000209290

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Reader Response: Association of Alternative Anticoagulation Strategies and Outcomes in Patients With Ischemic Stroke While Taking a Direct Oral Anticoagulant.

Saposnik, Gustavo

doi : 10.1212/WNL.0000000000209292

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Author Response: Association of Alternative Anticoagulation Strategies and Outcomes in Patients With Ischemic Stroke While Taking a Direct Oral Anticoagulant.

Ip, Yiu Ming Bonaventure; Leung, Thomas Wai Hong

doi : 10.1212/WNL.0000000000209291

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Frequency and Clinical Features of Space Headache Experienced by Astronauts During Long-Haul Space Flights.

van Oosterhout, Willebrordus P.J. MD, PhD; Perenboom, Matthijs J.L. PhD; Terwindt, Gisela M. MD, PhD; Ferrari, Michel D. MD, PhD; Vein, Alla A. MD, PhD

doi : 10.1212/WNL.0000000000209224

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CSF [beta]-Amyloid and Tau Biomarker Changes in Veterans With Mild Traumatic Brain Injury.

Li, Ge MD, PhD; Iliff, Jeffrey PhD; Shofer, Jane MS; Mayer, Cynthia L. DO; Meabon, James PhD; Cook, David PhD; Pagulayan, Kathleen F. PhD; Raskind, Murray A. MD; Zetterberg, Henrik MD, PhD; Blennow, Kaj MD, PhD; Peskind, Elaine R. MD

doi : 10.1212/WNL.0000000000209197

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Repetitive Blast Injury and CSF Alzheimer Disease Biomarkers: Navigating a Complex Narrative.

Alosco, Michael L. PhD; Tartaglia, Maria Carmela MD

doi : 10.1212/WNL.0000000000209294

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Cost-Effectiveness of Lecanemab for Individuals With Early-Stage Alzheimer Disease.

Nguyen, Hai V. PhD; Mital, Shweta PhD; Knopman, David S. MD; Alexander, G. Caleb MD

doi : 10.1212/WNL.0000000000209218

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Lecanemab for Alzheimer Disease: Is It Worth It?.

Nelson, Sarah E. MD, MPH; Lopez, Oscar L. MD

doi : 10.1212/WNL.0000000000209265

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Differences in Receipt of Neurologist Evaluation During Hospitalization for Ischemic Stroke by Race, Sex, Age, and Region: The REGARDS Study.

Hart, Stephanie PhD; Howard, George DrPH; Cummings, Doyle PharmD; Albright, Karen C. PhD, DO, MPH; Reis, Pamela PhD; Howard, Virginia J. PhD

doi : 10.1212/WNL.0000000000209200

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Location, Location, Location: Geographic Factors Drive Differential Receipt of Neurologist Evaluation After Stroke.

Mullen, Michael T. MD

doi : 10.1212/WNL.0000000000209288

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What Are the Roles of Cellular Prion Protein in Normal and Pathologic Conditions?.

Benarroch, Eduardo MD

doi : 10.1212/WNL.0000000000209272

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Teaching Video NeuroImage: Oculomotor Abnormalities in Patients With Alternating Hemiplegia of Childhood.

Azzoni, Andreia B. MD; Sakuma, Mayara T. MD; Sampaio, Leticia P. MD, PhD; De Gusmao, Claudio M. MD

doi : 10.1212/WNL.0000000000209313

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Lecanemab Questions.

Nadeau, Stephen E. MD

doi : 10.1212/WNL.0000000000209320

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Why Are You Here?.

Franklin, Gustavo L. MD, PhD

doi : 10.1212/WNL.0000000000209308

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Pearls & Oy-sters: Bibrachial Amyotrophy From a Dural Tear.

Sun, Yuyao MD; Pahwa, Shivani MD; Vasireddy, Rani Priyanka MBBS; Barty, Andrew DO; Raslau, Flavius D. MD

doi : 10.1212/WNL.0000000000209256

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Clinical Reasoning: A 19-Month-Old Girl With Infantile-Onset Myopathy and White Matter Changes.

Lail, Gurnoor MB, BCh, BAO; Siu, Victoria M. MD; Leung, Andrew MD

doi : 10.1212/WNL.0000000000209258

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Pearls & Oy-sters: KLHL11 IgG Paraneoplastic-Associated Hearing Loss and Rhombencephalitis in a Woman With Metastatic Mullerian Tumor.

Agyei, Paunel MD *; Chen, Michelle MD *; Guo, Yong MD, PhD; Perez, Carlos A. MD; Dubey, Divyanshu MD; Gupta, Rajesh K. MD

doi : 10.1212/WNL.0000000000209187

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Establishing Diagnostic Features of Traumatic Encephalopathy Syndrome: One Step at a Time.

Brett, Benjamin L. PhD; Beversdorf, David Q. MD

doi : 10.1212/WNL.0000000000209273

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Linking Type and Extent of Head Trauma to Cavum Septum Pellucidum in Older Adults With and Without Alzheimer Disease and Related Dementias.

Asken, Breton M. PhD, ATC; Tanner, Jeremy A. MD; Vandevrede, Lawren MD, PhD; Apple, Alexandra PhD; Chapleau, Marianne PhD; Gaynor, Leslie S. PhD; Lane-Donovan, Courtney MD, PhD; Lenio, Steven MD; Yadollahikhales, Golnaz MD; Lee, Shannon BA; Gontrum, Eva BA; Knudtson, Marguerite BA; Iaccarino, Leonardo PhD; La Joie, Renaud PhD; Cobigo, Yann PhD; Staffaroni, Adam M. PhD; Casaletto, Kaitlin B. PhD; Gardner, Raquel C. MD; Grinberg, Lea T. MD, PhD; Gorno-Tempini, Maria Luisa MD, PhD; Rosen, Howard J. MD; Seeley, William W. MD; Miller, Bruce L. MD; Kramer, Joel PsyD *; Rabinovici, Gil D. MD *

doi : 10.1212/WNL.0000000000209183

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Association of [beta]-Amyloid, Microglial Activation, Cortical Thickness, and Metabolism in Older Adults Without Dementia.

Cai, Yue PhD; Shi, Dai MD; Lan, Guoyu PhD; Chen, Linting MSc; Jiang, Yanni MSc; Zhou, Liemin MD; Guo, Tengfei PhD; for the Alzheimer's Disease Neuroimaging Initiative

doi :  10.1212/WNL.0000000000209205

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Efficacy and Safety of Tirofiban Before Stenting for Symptomatic Intracranial Atherosclerotic Stenosis: A Randomized Clinical Trial.

Zhang, Jun MD *; Huang, Xin MS *; Wang, Guoqing MD; Wang, Xianjun MD; Zhang, Tao MS; Wang, Dong MS; Qi, Lifeng MD; Liang, Jiye MS; Li, Bing MS; Chu, Jianfeng MS; Li, Kai MS; Sun, Lili MD; Song, Yun MD; Zhao, Wei MD; Zheng, Meimei MD; Meng, Yao MD; Yin, Hao MD; Wang, Wei MD; Han, Ju MD

doi : 10.1212/WNL.0000000000209217

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Free-Water Imaging of the Nucleus Basalis of Meynert in Patients With Idiopathic REM Sleep Behavior Disorder and Parkinson Disease.

Zhang, Dongling PhD *; Zhou, Liche MD, PhD *; Lu, Chenxi MD; Feng, Tao PhD; Liu, Jun PhD; Wu, Tao PhD

doi : 10.1212/WNL.0000000000209220

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Teaching Video NeuroImage: Adaptor-Related Protein-Complex-3 Subunit [beta]-2 Immunoglobulin-G-Associated Autoimmune Ataxia.

Kothapalli, Naga Pradyumna MBBS; Chompoopong, Pitcha MD; McKeon, Andrew MD; Dubey, Divyanshu MD

doi : 10.1212/WNL.0000000000209257

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Glycoproteome-Wide Discovery of Cortical Glycoproteins That May Provide Cognitive Resilience in Older Adults.

Buchman, Aron S. MD; Yu, Lei PhD; Klein, Hans-Ulrich PhD; Zammit, Andrea R. PhD; Oveisgharan, Shahram MD; Nag, Sukriti MD, PhD; Tickotsky, Nili DDS, PhD; Levy, Hila MSc; Seyfried, Nicholas PhD; Morgenstern, David PhD; Levin, Yishai PhD; Schnaider Beeri, Michal PhD; Bennett, David A. MD

doi : 10.1212/WNL.0000000000209223

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Stroke Thrombolysis: Can You Feel the Need for Speed?.

Nimjee, Shahid M. MD, PhD; Hill, Michael D. MD, MSc, FRCPC

doi : 10.1212/WNL.0000000000209253

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