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On standardization of controls in lifespan studies
Olga Spiridonova, Dmitrii Kriukov, Nikolai Nemirovich-Danchenko, Leonid Peshkin
doi : 10.18632/aging.205604
Volume 16, Issue 4
Multiple imputation of systematically missing data on gait speed in the Swedish National Study on Aging and Care
Robert Thiesmeier, Ahmad Abbadi, Debora Rizzuto, Amaia Calderón-Larrañaga, Scott M. Hofer, Nicola Orsini
doi : 10.18632/aging.205552
Mapping the core senescence phenotype of primary human colon fibroblasts
Namita Ganesh Hattangady, Kelly Carter, Brett Maroni-Rana, Ting Wang, Jessica Lee Ayers, Ming Yu, William M. Grady
doi : 10.18632/aging.205577
Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions
Edwin Lee, Natà lia Carreras-Gallo, Leilani Lopez, Logan Turner, Aaron Lin, Tavis L. Mendez, Hannah Went, Alan Tomusiak, Eric Verdin, Michael Corley, Lishomwa Ndhlovu, Ryan Smith, Varun B. Dwaraka
doi : 10.18632/aging.205581
Associations of prenatal one-carbon metabolism nutrients and metals with epigenetic aging biomarkers at birth and in childhood in a US cohort
Anne K. Bozack, Sheryl L. Rifas-Shiman, Andrea A. Baccarelli, Robert O. Wright, Diane R. Gold, Emily Oken, Marie-France Hivert, Andres Cardenas
doi : 10.18632/aging.205602
Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer’s disease by activated protein C
Mohammad Kasim Fatmi, Hao Wang, Lily Slotabec, Changhong Wen, Blaise Seale, Bi Zhao, Ji Li
doi : 10.18632/aging.205624
Single-cell and bulk RNA sequencing data jointly reveals VDAC2’s impacts on prognosis and immune landscape of NSCLC
Ying Ma, Bateer Han, Qin Yu, Nashunbayaer Zha, Zhiyuan Deng, Junguo Liang, Rong Yu
doi : 10.18632/aging.205517
The high expression of TOP2A and MELK induces the occurrence of psoriasis
Xinhua Zhu, Erjia Zhang, Li Qin
doi : 10.18632/aging.205519
Transcriptomic and network analysis identifies shared and unique pathways and immune changes across fibrotic interstitial lung diseases
Wenhao Liu, Kangping Huang, Xin-Zhuang Yang, Ping Wang
doi : 10.18632/aging.205530
Sodium tanshinone IIA sulfonate inhibits tumor growth via miR-138 upregulation in intermittent hypoxia-induced xenograft mice
Xiao-Bin Zhang, Qi-Feng Gan, Xiu-Zhen He, Ya-Ting Yuan, Ling-Wang, Mao-Hong Huang, Ping-Yang Hong
doi : 10.18632/aging.205531
Gut microbiota was highly related to the immune status in chronic obstructive pulmonary disease patients
Mei Wang, Jun Song, Huizhen Yang, Xiaoyu Wu, Jin Zhang, Sheng Wang
doi : 10.18632/aging.205532
BubR1 controls starvation-induced lipolysis via IMD signaling pathway in Drosophila
Mengyou Liu, Shengye Yang, Jingsi Yang, Ping Feng, Feng Luo, Qiaoqiao Zhang, Li Yang, Hao Jiang
doi : 10.18632/aging.205533
Disulfideptosis-associated lncRNAs reveal features of prognostic, immune escape, tumor mutation, and tumor malignant progression in renal clear cell carcinoma
Xungang Li, Xinxi Deng, Taobin Liu, Wensheng Zhang, Jin Tao
doi : 10.18632/aging.205534
Exosomes as nanostructures deliver miR-204 in alleviation of mitochondrial dysfunction in diabetic nephropathy through suppressing methyltransferase-like 7A-mediated CIDEC N6-methyladenosine methylation
Juan Jin, Yiwei Shang, Siqiang Zheng, Limiao Dai, Jiyu Tang, Xueyan Bian, Qiang He
doi : 10.18632/aging.205535
Machine learning constructs a T cell-related signature for predicting prognosis and drug sensitivity in ovarian cancer
Yunzheng Zhang, Lipeng Pei
doi : 10.18632/aging.205536
Single-cell transcriptomics identifies senescence-associated secretory phenotype (SASP) features of testicular aging in human
Junxian He, Jindong Li, Yanqing Li, Zhenhan Xu, Menghui Ma, Haicheng Chen, Peigen Chen, Linyan Lv, Xuejun Shang, Guihua Liu
doi : 10.18632/aging.205538
Pan-cancer analysis of NUDT21 and its effect on the proliferation of human head and neck squamous cell carcinoma
Wenjing Liu, Yingna Pang, Xiaolu Yu, Doudou Lu, Yating Yang, Fandi Meng, Chengbi Xu, Ling Yuan, Yi Nan
doi : 10.18632/aging.205539
Investigation on the mechanism of the combination of eremias multiocellata and cisplatin in reducing chemoresistance of gastric cancer based on in vitro and in vivo experiments
Fan-e Cheng, Zheng Li, Xing Bai, Yanyan Jing, Junfei Zhang, Xiaoqian Shi, Tingting Li, Weiqiang Li
doi : 10.18632/aging.205540
Orexin-A alleviates ferroptosis by activating the Nrf2/HO-1 signaling pathway in traumatic brain injury
Junwei Kang, Bingkai Ren, Lianghua Huang, Xiaoyang Dong, Qi Xiong, Zhen Feng
doi : 10.18632/aging.205541
Insights into serum metabolic biomarkers for early detection of incident diabetic kidney disease in Chinese patients with type 2 diabetes by random forest
Jian-Jun Jiang, Tung-Ting Sham, Xiu-Fen Gu, Chi-On Chan, Nai-Ping Dong, Wei-Han Lim, Gao-Feng Song, Shun-Min Li, Daniel Kam-Wah Mok, Na Ge
doi : 10.18632/aging.205542
Senescence-related genes analysis in breast cancer reveals the immune microenvironment and implications for immunotherapy
Hua Zhong, Lijie Chang, Shengbin Pei, Yakun Kang, Lili Yang, Yifan Wu, Nuo Chen, Yicheng Luo, Yixiao Zhou, Jiaheng Xie, Yiqin Xia
doi : 10.18632/aging.205544
Investigation of cuproptosis regulator-mediated modification patterns and SLC30A7 function in GBM
Wanli Yu, Shikai Gui, Jiabao Xie, Lunshan Peng, Juexian Xiao, Haitao Luo, Zhennan Tao, Zujue Cheng
doi : 10.18632/aging.205545
Rutin promotes osteogenic differentiation of mesenchymal stem cells (MSCs) by increasing ECM deposition and inhibiting p53 expression
Dongyang Li, Wanru Yin, Chao Xu, Yongmin Feng, Xin Huang, Junfeng Hao, Chao Zhu
doi : 10.18632/aging.205546
Causal relationship between gut microbiota and risk of esophageal cancer: evidence from Mendelian randomization study
Kui Wang, Jiawei Wang, Yuhua Chen, Huan Long, Wei Pan, Yunfei Liu, Ming-Yi Xu, Qiang Guo
doi : 10.18632/aging.205547
New insights into ginsenoside Rg1 regulating the niche to inhibit age-induced germline stem cells depletion through targeting ECR/BMP signaling pathway in Drosophila
Baoyu Fu, Rui Ma, Fangbing Liu, Xuenan Chen, Manying Wang, Wenqi Jin, Shuai Zhang, Yanping Wang, Liwei Sun
doi : 10.18632/aging.205548
The clinicopathologic and molecular features, and treatment outcome of fumarate hydratase-deficient renal cell carcinoma: a retrospective comparison with type 2 papillary renal cell carcinoma
Junjie Bai, Xiaoyan Li, Yahui Wen, Qing Lu, Ru Chen, Rong Liu, Tong Shangguan, Yushi Ye, Jun Lin, Weizhong Cai, Deyong Kang, Jianhui Chen
doi : 10.18632/aging.205549
Comprehensive analysis of disulfidptosis-related genes: a prognosis model construction and tumor microenvironment characterization in clear cell renal cell carcinoma
Bocun Yi, Xifeng Wei, Dongze Liu, Liwei Jing, Shengxian Xu, Man Zhang, Zhengxin Liang, Ranlu Liu, Zhihong Zhang
doi : 10.18632/aging.205550
Prognostic value and therapeutic potential of IAP family in head and neck squamous cell carcinoma
Xiaoqian Yu, Weiwei Cao, Xuejie Yang, Canping Yu, Wenying Jiang, Hongbin Guo, Xiaoyun He, Cheng Mei, Chunlin Ou
doi : 10.18632/aging.205551
PMAIP1, a novel diagnostic and potential therapeutic biomarker in osteoporosis
Tao Li, Jinghong Yuan, Peichuan Xu, Jingyu Jia, Jiangminghao Zhao, Jian Zhang, Rui Ding, Xiaokun Zhao, Dingwen He, Tianlong Wu, Xigao Cheng
doi : 10.18632/aging.205553
miR-557 inhibits hepatocellular carcinoma progression through Wnt/β-catenin signaling pathway by targeting RAB10
Xiaoye Cheng, Can Wu, Haocheng Xu, Ruixiang Zou, Taiyuan Li, Shanping Ye
doi : 10.18632/aging.205554
Identification of hypoxic-related lncRNAs prognostic model for revealing clinical prognostic and immune infiltration characteristic of cutaneous melanoma
Congjuan Liao, Jiabao Yang, Liuting Chen, Zhiguang Ye
doi : 10.18632/aging.205556
Suppression of cerebral ischemia injury induced blood brain barrier breakdown by dexmedetomidine via promoting CCN1
Shuangmei Liu, Xuepeng Jia, Bo Liu, Yue Liu, Hong Yin
doi : 10.18632/aging.205557
Liraglutide improves sevoflurane-induced postoperative cognitive dysfunction via activating autophagy and inhibiting apoptosis
Ying Hu, Haijin Huang, Yao Jiang, Jingling Zhang, Yang Zhang, Ying Tian, Qin Zhang
doi : 10.18632/aging.205558
Yangyinghuoxue decoction exerts a treatment effect on hepatic fibrosis by PI3K/AKT pathway in rat model: based on the network pharmacology and molecular docking
Yan-Ming Bai, Shuang Liang, Bo Zhou
doi : 10.18632/aging.205559
MUC1 promotes RIF by regulating macrophage ROS-SHP2 signaling pathway to up-regulate inflammatory response and inhibit angiogenesis
Rongna Liu, Lin Chen, Xin Zhao, Lili Bao, Ruixia Wei, Xiaohua Wu
doi : 10.18632/aging.205560
Mitochondrial-related genes PDK2, CHDH, and ALDH5A1 served as a diagnostic signature and correlated with immune cell infiltration in ulcerative colitis
Qian Yang, Peng Zhang, Lu Han, Pengshuang Shi, Zhifang Zhao, Dejun Cui, Kunqiao Hong
doi : 10.18632/aging.205561
Development and validation of a nomogram for predicting the impact of tumor size on cancer-specific survival of locally advanced renal cell carcinoma: a SEER-based study
Junjie Bai, Qing Lu, Yahui Wen, Tong Shangguan, Yushi Ye, Jun Lin, Rong Liu, Weizhong Cai, Jianhui Chen
doi : 10.18632/aging.205562
Dickkopf-1 is an immune infiltration-related prognostic biomarker of head and neck squamous cell carcinoma
Chaofen Zhao, Lina Liu, Qianyong He, Yuanyuan Li, Jianglong Feng, Yue Chen, Yuxin Li, Xinyu Xu, Shaoyuan Zhu, Yuanmei Ye, Yajing Wen, Zhirui Zeng, Ding’an Zhou, Feng Jin
doi : 10.18632/aging.205563
An assessment system for clinical and biological interpretability in ulcerative colitis
Shiqian Zhang, Ge Zhang, Wenxiu Wang, Song-Bin Guo, Pengpeng Zhang, Fuqi Wang, Quanbo Zhou, Zhaokai Zhou, Yujia Wang, Haifeng Sun, Wenming Cui, Shuaixi Yang, Weitang Yuan
doi : 10.18632/aging.205564
Comprehensive analysis identifies crucial genes associated with immune cells mediating progression of carotid atherosclerotic plaque
Zhen Li, Junhui Liu, Zhichun Liu, Xiaonan Zhu, Rongxin Geng, Rui Ding, Haitao Xu, Shulan Huang
doi : 10.18632/aging.205566
GAS5, a long noncoding RNA, contributes to annulus fibroblast osteogenic differentiation and apoptosis in intervertebral disk degeneration via the miR-221-3p/SOX11 axis
Qi Liu, Jiaying Luo, Huan Wang, Lei Zhang, Jingwen Guo, Guoxin Jin
doi : 10.18632/aging.205567
Validation and identification of anoikis-related lncRNA signatures for improving prognosis in clear cell renal cell carcinoma
Zhenjie Zhu, Qibo Wang, Xiaowei Zeng, Shaoxing Zhu, Jinchao Chen
doi : 10.18632/aging.205568
Functional enrichment analysis reveals the involvement of DARS2 in multiple biological pathways and its potential as a therapeutic target in esophageal carcinoma
Xu-Sheng Liu, Zi-Yue Liu, Dao-Bing Zeng, Jian Hu, Xuan-Long Chen, Jiao-Long Gu, Yan Gao, Zhi-Jun Pei
doi : 10.18632/aging.205569
Protective effects of triptolide against oxidative stress in retinal pigment epithelium cells via the PI3K/AKT/Nrf2 pathway: a network pharmacological method and experimental validation
Fuying Pan, Qinxin Shu, Hao Xie, Long Zhao, Ping Wu, Yong Du, Jing Lu, Yuxia He, Xing Wang, Hui Peng
doi : 10.18632/aging.205570
MicroRNA-320a enhances LRWD1 expression through the AGO2/FXR1-dependent pathway to affect cell behaviors and the oxidative stress response in human testicular embryonic carcinoma cells
Yi-Hsiung Lin, Chia-Hui Su, Hsin-Mei Chen, Ming-Syuan Wu, Hsien-An Pan, Chia-Ning Chang, Yu-Sheng Cheng, Wen-Tsan Chang, Chien-Chih Chiu, Yen-Ni Teng
doi : 10.18632/aging.205571
Unlocking the potential of senescence-related gene signature as a diagnostic and prognostic biomarker in sepsis: insights from meta-analyses, single-cell RNA sequencing, and in vitro experiments
Jia Chen, Jinhong Si, Qiankun Li, Weihong Zhang, Jiahao He
doi : 10.18632/aging.205574
Subtype recognition and identification of a prognosis model characterized by antibody-dependent cell phagocytosis-related genes in breast cancer
Li Wang, Menghan Li, Hongyu Yang, Fenghuan Dai, Ning Xie, Linhui Li, Meiying Zhu, Ran Ding
doi : 10.18632/aging.205575
LGALS3BP is a novel and potential biomarker in clear cell renal cell carcinoma
Lei Li, Sen Qin, Hongwei Tan, Jiexue Zhou
doi : 10.18632/aging.205578
The role of long non-coding RNA in hepatocellular carcinoma
Weizheng Liang, Yan Zhao, Qingxue Meng, Wenjie Jiang, Shoulong Deng, Jun Xue
doi : 10.18632/aging.205523
Correction for: A novel six-microRNA-based model to improve prognosis prediction of breast cancer
Jianguo Lai, Hongli Wang, Zihao Pan, Fengxi Su
doi : 10.18632/aging.205643
