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Do increased risks of cancer mean we need to change our approach to treatment?
Aditi Senthilnathan & Steven R. Feldman
doi : 10.1080/09546634.2020.1830930
Pages: 1-2
Dermocosmetics: beneficial adjuncts in the treatment of acne vulgaris
Elena Araviiskaia, Jose Luis Lopez Estebaranz & Carlo Pincelli
doi : 10.1080/09546634.2019.1628173
Pages: 3-10
Introduction: Dermocosmetics are increasingly being recognized as an integral part of acne management. Dermocosmetics may minimize the side effects of acne medications, provide synergistic effects by improving the efficacy of other treatments, and limit exposure to environmental factors such as ultraviolet radiation. We aimed to provide an overview of the active ingredients and different types of preparations used in dermocosmetics for acne, and highlight supporting evidence for their use in clinical practice.
Non-pharmacologic approaches for hidradenitis suppurativa – a systematic review
Aleksi J. Hendricks, Penelope A. Hirt, Sahil Sekhon, Alexandra R. Vaughn, Hadar A. Lev-Tov, Jennifer L. Hsiao & Vivian Y. Shi
doi : 10.1080/09546634.2019.1621981
Pages: 11-18
Importance: Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition presenting with painful nodules and sinus tracts primarily in intertriginous regions. The persistent nature of HS and challenges in symptom management lead many patients to seek non-pharmacologic approaches due to the paucity and limited efficacy of conventional HS therapeutic options.
Dupilumab use in dermatologic conditions beyond atopic dermatitis – a systematic review
Aleksi J. Hendricks, Gil Yosipovitch & Vivian Y. Shi
doi : 10.1080/09546634.2019.1689227
Pages: 19-28
Importance: While dupilumab has emerged as an effective treatment for moderate-to-severe atopic dermatitis (AD) since its approval in 2017, interleukin-4 and 13 blockade has also demonstrated efficacy in off-label chronic dermatologic conditions.
Neonatal epidermolysis bullosa: lessons to learn about genetic counseling
Shuk Ching Chong, Kam Lun Hon, Liz Y. P. Yuen, Paul Cheung Lung Choi, W. G. Gigi Ng & Tor W. Chiu
doi : 10.1080/09546634.2018.1527999
Pages: 29-32
Epidermolysis Bullosa (EB) is a heterogeneous group of congenital blistering diseases that usually presents in the neonatal period. EB is classified into three major categories, each with many subtypes based on the precise location at which separation or blistering occurs, namely epidermolysis bullosa simplex (EBS), junctional epidermolysis bullosa (JEB) and dystrophic epidermolysis bullosa (DEB).
Efficacy and safety of biosimilar rituximab in patients with pemphigus vulgaris: a prospective observational study
Roja Toosi, Hamidreza Mahmoudi, Kamran Balighi, Amir Teimourpour, Hoorieh Alaeen, Mohammadreza Shaghaghi, Robabeh Abedini & Maryam Daneshpazhooh
doi : 10.1080/09546634.2019.1617831
Pages: 33-40
Background: The optimal treatment for pemphigus vulgaris (PV) has not been clearly determined yet. Rituximab (RTX) was recently approved for the management of adults with moderate to severe PV.
Is topical treatment effective for psoriasis in patients who failed topical treatment?
Nwanneka Okwundu, Leah Cardwell, Abigail Cline, Irma Richardson & Steven R. Feldman
doi : 10.1080/09546634.2019.1617830
Pages: 41-44
Objectives: To determine if resistance to topical treatments can be overcome under conditions promoting adherence.
Are skin equipment for assessing childhood eczema any good?
Kam Lun Hon, Jeng Sum C. Kung, W. G. Ng, K. Y. C. Tsang, Nancy Cheng & Ting Fan Leung
doi : 10.1080/09546634.2018.1442551
Pages: 45-48
Symptomatology and severity of atopic dermatitis (AD) can be objectively measured with equipment. This study aimed to compare skin measurements and investigate their correlations with various clinical severity scores.
A systematic review of treatment strategies for erythrodermic psoriasis
Kelly A. Reynolds, Deeti J. Pithadia, Erica B. Lee, Wilson Liao & Jashin J. Wu
doi : 10.1080/09546634.2019.1689228
Pages: 49-55
Background: Erythrodermic psoriasis (EP) is a severe, rare form of psoriasis that can be life threatening. Treatment of EP is usually based on anecdotal evidence or past clinical experience, which is in part due to the rarity and often emergent nature of this psoriasis subtype.
Ixekizumab treatment patterns and healthcare utilization and costs for patients with psoriasis
Mwangi J. Murage, Adrienne M. Gilligan, Oth Tran, Orin Goldblum, Russel Burge, Chen-Yen Lin & Abrar Qureshi
doi : 10.1080/09546634.2019.1690622
Pages: 56-63
Factors affecting adherence and patient satisfaction with treatment: a cross-sectional study of 500 patients with acne vulgaris
Y?ld?z Hayran, P?nar ?ncel Uysal, Ay?e ?ktem, Güne? Gür Aksoy, Neslihan Akdo?an & Ba?ak Yalç?n
doi : 10.1080/09546634.2019.1618434
Pages: 64-69
Background: Acne Vulgaris is a chronic inflammatory disease that requires long-term treatment. Adherence to treatment is a problem in chronic diseases and may affect treatment outcomes.
Antibiotic prescribing trends among US dermatologists in Medicare from 2013 to 2016
Efe Kakpovbia, Hao Feng, Paula W. Feng & Jeffrey M. Cohen
doi : 10.1080/09546634.2019.1623372
Pages: 70-72
Objectives: Antibiotics are commonly used in dermatology for infectious and inflammatory diseases, and dermatologists prescribe the most antibiotics per physician of any specialist in the United States (US). While oral antibiotics are effective for many conditions, adverse effects and increase in resistance are important public health issues. The purpose of this study is to examine trends in oral antibiotic prescription by US dermatologists using Medicare claims.
Objective analysis of volume restoration in atrophic acne scars and skin pores: a split study using human stem cell-conditioned media
Chan Seong Park, Ji-Hye Park, Cho Rok Kim & Jong Hee Lee
doi : 10.1080/09546634.2019.1628915
Pages: 73-77
Background: It is anticipated that the combined treatments of ablative laser and human stem cell-conditioned media produce the synergistic effects.
Photodynamic therapy for actinic keratosis in vegan and omnivore patients: the role of diet on skin healing
Marta Fusano, Cristina Zane, PierGiacomo Calzavara-Pinton & Pier Luca Bencini
doi : 10.1080/09546634.2019.1618433
Pages: 78-83
Background: Photodynamic therapy (PDT) is an approved and effective treatment for actinic keratosis (AK). The time of complete skin healing is estimated to range between 5 and 10 days, but the role of nutrition in influencing it has never been evaluated.
Checkmark rotation flap for nasal tip reconstruction in Asian patients
Byung Ho Oh, Yeongjoo Oh, Kyoung Ae Nam, Mi Ryung Roh & Kee Yang Chung
doi : 10.1080/09546634.2019.1629385
Pages: 84-89
Background: Nasal tip reconstruction (NTR) of the Mohs defect is challenging, especially in Asians who have a relatively low nasal bridge and thin cartilages.
The clinical efficacy of treatment using the autologous non-cultured epidermal cell suspension technique for stable vitiligo in 41 patients
Bin Liu, Hui-Heng Chen, Zhong-Hai Liu, Jing-Feng Liang, Ru-Jun Xue, Ping-Jiao Chen, Chang-Xing Li, Xiao-Dong Liang, Jie Deng, Rui-Xian Ye, Xi-Bao Zhang & Jing-Yao Liang
doi : 10.1080/09546634.2019.1619657
Pages: 90-94
Background: Vitiligo is an acquired depigmentation skin disorder mainly caused by the destruction of melanocytes. There are many therapeutic options available for vitiligo, but the options are not uniformly effective.
The efficacy and safety of BM-PHA for the correction of nasolabial folds: a multicenter, randomized, double-blind, split-face clinical trial
Seung Hwan Paik, Myoung Eun Choi, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Jee Ho Choi, Beom Joon Kim & Chong Hyun Won
doi : 10.1080/09546634.2019.1623859
Pages: 95-100
Background: Multiple types of fillers have been developed for soft tissue augmentation.
Low-dose total skin electron beam therapy for refractory cutaneous CD30 positive lymphoproliferative disorders
Neil Panjwani, Christopher H Yoo, Erica Wang, Michael S. Khodadoust, Youn H. Kim, Richard T Hoppe & Susan M. Hiniker
doi : 10.1080/09546634.2019.1628913
Pages: 101-103
We describe a case of a 48-year-old woman with a refractory cutaneous CD30 positive lymphoproliferative disorder treated successfully with total skin electron beam radiotherapy (TSEBT).
Efficacy and safety of colchicine in inflammatory skin diseases: a retrospective, monocentric study in a large tertiary center
Florian Anzengruber, Vanessa Graf, Jürg Hafner, Nina Meienberger, Emmanuella Guenova & Reinhard Dummer
doi : 10.1080/09546634.2019.1690621
Pages: 104-109
Introduction: Colchicine is an ancient, but rarely used drug. Little data exist on its efficacy and safety in patients suffering from skin diseases. The objective of our study was to determine whether colchicine showed favorable efficacy and safety in our patients during the last 20?years.
Rosacea fulminans: two case reports and review of the literature
L. Angileri, S. Veraldi & M. Barbareschi
doi : 10.1080/09546634.2019.1628175
Pages: 110-113
Rosacea fulminans is a rare and severe inflammatory dermatosis which affects predominantly childbearing women. It is characterized by sudden onset and it usually localizes exclusively on the centrofacial areas, presenting with numerous fluctuant inflammatory nodules and papules which may coalesce.
Rosacea associated with dupilumab therapy
Haley D. Heibel, Aleksi J. Hendricks, James P. Foshee & Vivian Y. Shi
doi : 10.1080/09546634.2019.1624683
Pages: 114-116
Background: Dupilumab is used for treatment of atopic dermatitis through blockade of IL-4 and IL-13 signaling of the Th2 pathway. Recent case reports have described alopecia, psoriasis, persistent facial dermatitis, and recall dermatitis at patch test sites after the initiation of dupilumab therapy.
Treatment of acrodermatitis continua of hallopeau with ixekizumab
Austinn C. Miller, Timothy E. Holland & David J. Cohen
doi : 10.1080/09546634.2019.1628170
Pages: 117-119
Acrodermatitis continua of hallopeau (ACH) is a rare chronic inflammatory variant of pustular psoriasis often restricted to the distal portions the digits in the hands and feet. ACH is of a chronic relapsing nature and is invariably recalcitrant to many available topical and systemic anti-psoriatic therapies. On account of its low prevalence and high resistance to treatments, no clinical guideline of ACH exists. We present a patient with ACH resistant to multiple therapies, including the biologic adalimumab, who was successfully treated with an IL-17 inhibitor (ixekizumab). We believe our unique treatment with an excellent outcome may assist other dermatologists if faced with this condition.
CO2 laser treatment of a kissing nevus of the penis: an alternative solution for a rare condition
Bernardo Correia, Ana F. Duarte, Eckart Haneke & Osvaldo Correia
doi : 10.1080/09546634.2019.1629384
Pages: 120-123
Divided or kissing nevi are a rare clinical variant of congenital melanocytic nevi developing in adjacent areas of the skin that undergo cleavage during embryogenesis. Penile lesions are even rarer, with only few cases described in the literature. Typically, they present as two opposing dark colored macular or papular lesions on the glans and prepuce, exhibiting a mirror-image symmetry relative to the coronal sulcus. The proposed management ranges from clinical follow-up to surgical excision. However, in this particularly sensitive location the risk of functional and esthetical complications is high, so an alternative treatment option was proposed. We report a case of a penile kissing nevus with its dermoscopic and histopathological characteristics as well as its successful treatment with the carbon dioxide (CO2) laser.
Tricyclic antidepressants for the treatment of chronic pruritus
Emily Boozalis, Raveena Khanna, John G. Zampella & Shawn G. Kwatra
doi : 10.1080/09546634.2019.1623369
Pages: 124-126
Real-life practice: rapid improvement in itch symptomatology in patients with atopic dermatitis treated with dupilumab
Giuseppe Pistone, Giovanna Tilotta, Rosario Gurreri, Elena Castelli, Salvatrice Curiale & Maria Rita Bongiorno
doi : 10.1080/09546634.2019.1628914
Page: 127
Cannabinoids: a possible treatment for chronic cutaneous wounds
Kamran Mansouri & Amir Hossein Norooznezhad
doi : 10.1080/09546634.2019.1690620
Pages: 128-129
