Acta Pharmacologica Sinica




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Lipid droplets in pathogen infection and host immunity

Yan-jie Tan, Yi Jin, Jun Zhou & Yun-fan YangÂ

doi : 10.1038/s41401-023-01189-1

Volume 45 Issue 3, March 2024

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Schisandrin B, a dual positive allosteric modulator of GABAA and glycine receptors, alleviates seizures in multiple mouse models

Jun Wu, Miao Zhao, Yu-chen Jin, Min Li, Ke-xin Yu & Hai-bo YuÂ

doi : 10.1038/s41401-023-01195-3

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Baicalein attenuates rotenone-induced SH-SY5Y cell apoptosis through binding to SUR1 and activating ATP-sensitive potassium channels

De-wen Kong, Li-da Du, Run-zhe Liu, Tian-yi Yuan, Shou-bao Wang, Yue-hua Wang, Yang Lu, Lian-hua Fang & Guan-hua DuÂ

doi : 10.1038/s41401-023-01187-3

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The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation

Shi-hao Cui, Na Suo, Ying Yang, Xuan Wu, Shi-meng Guo & Xin XieÂ

doi : 10.1038/s41401-023-01183-7

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Activation of the PERK-CHOP signaling pathway during endoplasmic reticulum stress contributes to olanzapine-induced dyslipidemia

Lu Liu, Lei Tang, Jia-ming Luo, Si-yu Chen, Chun-yan Yi, Xue-mei Liu & Chang-hua HuÂ

doi : 10.1038/s41401-023-01180-w

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Cardiac-specific deletion of BRG1 ameliorates ventricular arrhythmia in mice with myocardial infarction

Jing Li, Zi-yue Ma, Yun-feng Cui, Ying-tao Cui, Xian-hui Dong, Yong-zhen Wang, Yu-yang Fu, Ya-dong Xue, Ting-ting Tong, Ying-zi Ding, Ya-mei Zhu, Hai-jun Huang, Ling Zhao, Hong-zhao Lv, Ling-zhao Xiong, Kai Zhang, Yu-xuan Han, Tao Ban & Rong HuoÂ

doi : 10.1038/s41401-023-01170-y

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Isoproterenol induces MD2 activation by β-AR-cAMP-PKA-ROS signalling axis in cardiomyocytes and macrophages drives inflammatory heart failure

Jin-fu Qian, Shi-qi Liang, Qin-yan Wang, Jia-chen Xu, Wu Luo, Wei-jian Huang, Gao-jun Wu & Guang LiangÂ

doi : 10.1038/s41401-023-01179-3

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Role of thrombospondin-1 in high-salt–induced mesenteric artery endothelial impairment in rats

Fang-fang Xu, Fan Zheng, Ye Chen, Yang Wang, Shao-bo Ma, Weng Ding, Le-sha Zhang, Ji-zheng Guo, Chang-Bo Zheng & Bing ShenÂ

doi : 10.1038/s41401-023-01181-9

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ASH2L upregulation contributes to diabetic endothelial dysfunction in mice through STEAP4-mediated copper uptake

Wen Zhong, Ye-jun Dong, Chen Hong, Yu-hui Li, Chen-xi Xiao, Xin-hua Liu & Jun ChangÂ

doi : 10.1038/s41401-023-01174-8

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Amuc_1100 pretreatment alleviates acute pancreatitis in a mouse model through regulating gut microbiota and inhibiting inflammatory infiltration

Li-juan Wang, Yuan-ling Jin, Wen-long Pei, Jia-cong Li, Rui-lin Zhang, Jia-ju Wang & Wei LinÂ

doi : 10.1038/s41401-023-01186-4

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Colon-targeted S100A8/A9-specific peptide systems ameliorate colitis and colitis-associated colorectal cancer in mouse models

Euni Cho, Seok-Jun Mun, Hyo Keun Kim, Yu Seong Ham, Woo Jin Gil & Chul-Su YangÂ

doi : 10.1038/s41401-023-01188-2

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Blocking reverse electron transfer-mediated mitochondrial DNA oxidation rescues cells from PANoptosis

Fu-li Shi, Qing Li, Rong Xu, Li-sha Yuan, Ying Chen, Zi-jian Shi, Ya-ping Li, Zhi-ya Zhou, Li-hui Xu, Qing-bing Zha, Bo Hu, Xian-hui He & Dong-yun Ou-yangÂ

doi : 10.1038/s41401-023-01182-8

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A novel human single-domain antibody-drug conjugate targeting CEACAM5 exhibits potent in vitro and in vivo antitumor activity

Xiao-yi Zhu, Quan-xiao Li, Yu Kong, Ke-ke Huang, Gang Wang, Yun-ji Wang, Jun Lu, Guo-qiang Hua, Yan-ling Wu & Tian-lei YingÂ

doi : 10.1038/s41401-023-01200-9

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Phenethyl isothiocyanate inhibits metastasis potential of non-small cell lung cancer cells through FTO mediated TLE1 m6A modification

Qi-cheng Zhang, Yong-mei Qian, Ying-hui Ren, Meng-meng Chen, Li-min Cao, Si-jia Zheng, Bing-bing Li, Min Wang, Xiang Wu & Ke XuÂ

doi : 10.1038/s41401-023-01178-4

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Combination of eriocalyxin B and homoharringtonine exerts synergistic anti-tumor effects against t(8;21) AML

Yi-chen Lei, Xin-jie Chen, Yu-ting Dai, Bing Dai, Ji-yue Wang, Miao-hui Li, Ping Liu, Han Liu, Kan-kan Wang, Lu Jiang & Bing ChenÂ

doi : 10.1038/s41401-023-01196-2

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Reexamining the effects of drug loading on the in vivo performance of PEGylated liposomal doxorubicin

Yi-fei Yu, Er-can Wu, Shi-qi Lin, Yu-xiu Chu, Yang Yang, Feng Pan, Tian-hao Ding, Jun Qian, Kuan Jiang & Chang-you ZhanÂ

doi : 10.1038/s41401-023-01169-5

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Author Correction: DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer

Xiang-ling Chen, Peng Liu, Wei-liang Zhu & Li-guang LouÂ

doi : 10.1038/s41401-023-01184-6

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