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GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects
Hyun-Hee Park, Hyuk Sung Kwon, Kyu-Yong Lee, Ye Eun Kim, Jeong-Woo Son, Na-Young Choi, Myung-Hoon Han, Dong Woo Park, Sangjae Kim, Seong-Ho Koh
doi : 10.18632/aging.205489
Volume 16, Issue 3
The anti-aging effect of vitamin D and vitamin D receptor in Drosophila midgut
Joung-Sun Park, Hyun-Jin Na, Yung-Jin Kim
doi : 10.18632/aging.205518
Defining the progeria phenome
Cecilie Worm, Maya Elena Ramirez Schambye, Garik V. Mkrtchyan, Alexander Veviorskiy, Anastasia Shneyderman, Ivan V. Ozerov, Alex Zhavoronkov, Daniela Bakula, Morten Scheibye-Knudsen
doi : 10.18632/aging.205537
Disruption of mitochondrial unfolded protein response results in telomere shortening in mouse oocytes and somatic cells
Mauro Cozzolino, Yagmur Ergun, Emma Ristori, Akanksha Garg, Gizem Imamoglu, Emre Seli
doi : 10.18632/aging.205543
LncRNA MEG3 inhibits the proliferation and migration abilities of colorectal cancer cells by competitively suppressing MiR-31 and reducing the binding of MiR-31 to target gene SFRP1
Zheli Li, Zhi Zhao, Gang Zhang, Yufeng Liu, Shaohua Zheng
doi : 0.18632/aging.205274
Lactobacillus plantarum ST-III culture supernatant protects against acute alcohol-induced liver and intestinal injury
Feng Xu, Zengqiang Chen, Longteng Xie, Shizhuo Yang, Yuying Li, Junnan Wu, Yuyu Wu, Siyuan Li, Xie Zhang, Yanyan Ma, Yanlong Liu, Aibing Zeng, Zeping Xu
doi : 10.18632/aging.205331
MAEL in human cancers and implications in prognostication and predicting benefit from immunotherapy over VEGFR/mTOR inhibitors in clear cell renal cell carcinoma: a bioinformatic analysis
Jin Tao, Jinshan Cui, Yu Xu, Yafeng Fan, Guodong Hong, Qiaoxia Zhou, Guoqiang Wang, Leo Li, Yusheng Han, Chunwei Xu, Wenxian Wang, Shangli Cai, Xuepei Zhang
doi : 10.18632/aging.205470
Identification of renal ischemia reperfusion injury-characteristic genes, pathways and immunological micro-environment features through bioinformatics approaches
Xinghua Lv, Qian Fan, Xuanjie Li, Peng Li, Zhanhai Wan, Xuena Han, Hao Wang, Xiaoxia Wang, Lin Wu, Bin Huo, Li Yang, Gen Chen, Yan Zhang
doi : 10.18632/aging.205471
Moxibustion prevents tripterygium glycoside-induced oligoasthenoteratozoospermia in rats via reduced oxidative stress and modulation of the Nrf2/HO-1 signaling pathway
Shangjie Liang, Yaqun Yin, Zhizi Zhang, Yansu Fang, Ge Lu, Hongxiao Li, Yaoli Yin, Meihong Shen
doi : 10.18632/aging.205475
Integrative analysis of LAG3 immune signature and identification of a LAG3-related genes prognostic signature in kidney renal clear cell carcinoma
Jie Li, Chungan Liu, Hui Su, Hao Dong, Zhiqian Wang, Yuqi Wang, Peng Zhao, Chaowei Zhang, Yi Zhao, Xuezhen Ma
doi : 10.18632/aging.205476
(-)-Epicatechin protects against myocardial ischemia/reperfusion injury via autophagy-dependent ferroptosis
Kong Junhong, Tsai Yun, Shui Guangxing, Ding Yuhan, Xiang Qian, Zhang Haowen
doi : 10.18632/aging.205477
Generating detailed intercellular communication patterns in psoriasis at the single-cell level using social networking, pattern recognition, and manifold learning methods to optimize treatment strategies
Ying Xiong, Sidi Li, Yunmeng Bai, Ting Chen, Wenwen Sun, Lijie Chen, Jia Yu, Liwei Sun, Chijun Li, Jiajian Wang, Bo Wu
doi : 10.18632/aging.205478
Identification of an immune-related eRNA prognostic signature for clear cell renal cell carcinoma
Yang Lv, Lili Niu, Qiang Li, Wenchuan Shao, Xinghan Yan, Yang Li, Yulin Yue, Hongqi Chen
doi : 10.18632/aging.205479
Identification of gut microbes-related molecular subtypes and their biomarkers in colorectal cancer
Xuliang Liu, Guolin Zhang, Shiyao Li, Yuechuan Liu, Kexin Ma, Liming Wang
doi : 10.18632/aging.205480
Prognostic value and immune landscapes of anoikis-associated lncRNAs in lung adenocarcinoma
Bo Wu, Xiang Zhang, Nan Feng, Zishun Guo, Lu Gao, Zhihua Wan, Wenxiong Zhang
doi : 10.18632/aging.205481
Identification of molecular characteristics of FUT8 and alteration of core fucosylation in kidney renal clear cell cancer
Zhu Xin, Xinyu Wen, Mengying Zhou, Hongli Lin, Jia Liu
doi : 10.18632/aging.205482
Comprehensive analysis of ALG3 in pan-cancer and validation of ALG3 as an onco-immunological biomarker in breast cancer
Xiaolei Xue, Qiaoli Feng, Xi Hong, Zhousheng Lin, Yingrui Luo, Yingshi Li, Guangyu Yao, Nisha Wang, Lujia Chen
doi : 10.18632/aging.205483
5-methylcytosine RNA modification regulators-based patterns and features of immune microenvironment in acute myeloid leukemia
Yuhong Ding, Akhilesh K. Bajpai, Fengxia Wu, Weihua Lu, Lin Xu, Jiawei Mao, Qiang Li, Qi Pan, Lu Lu, Xinfeng Wang
doi : 10.18632/aging.205484
Prepared Radix Polygoni Multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition
Changyudong Huang, Yiqiong Zhang, Yongjie Xu, Sijia Wei, Tingting Yang, Shuang Wang, Chengcheng Li, Hairong Lin, Xing Li, Shuyun Zhao, Liying Zhu, Wei Pan
doi : 10.18632/aging.205485
Ethanol extract of Evodia lepta Merr. ameliorates cognitive impairment through inhibiting NLRP3 inflammasome in scopolamine-treated mice
Rui-Dan Hu, Wen-Li Zhu, Wei-Yao Lin, Yu-Hui Qiu, Guang-Liang Wu, Xiao-Ying Ding, Zhen-Kun Yang, Qian Feng, Rong-Rong Zhang, Li-Jun Qiao, Ye-Feng Cai, Shi-Jie Zhang
doi : 10.18632/aging.205486
Inhibitory effect of a novel Curcumin derivative DMC-HA on keloid fibroblasts
Liang Hu, Zhicheng Bao
doi : 10.18632/aging.205487
A novel PANoptosis-related long non-coding RNA index to predict prognosis, immune microenvironment and personalised treatment in hepatocellular carcinoma
Liangliang Wang, Peng Wan, Zhengyang Xu
doi : 10.18632/aging.205488
Interaction of Sp1 and Setd8 promotes vascular smooth muscle cells apoptosis by activating Mark4 in vascular calcification
Yun Li, Meijuan Cheng, Jingjing Jin, Dongxue Zhang, Shenglei Zhang, Yaling Bai, Jinsheng Xu
doi : 10.18632/aging.205492
MRPS23 is a novel prognostic biomarker and promotes glioma progression
Qiang Wang, Guiqing Chen, Liang Liu, Xiaoying Peng, Xian Yang, Ling Yang, Chunhong Li
doi : 10.18632/aging.205493
KLF3 promotes colorectal cancer growth by activating WNT1
Wei Shen, Lebin Yuan, Boyu Hao, Jiajia Xiang, Fei Cheng, Zhao Wu, Xiaodong Li
doi : 10.18632/aging.205494
Risk model based on genes regulating the response of tumor cells to T-cell-mediated killing in esophageal squamous cell carcinoma
Xun Zhang, Chuting Yu, Siwei Zhou, Yanhui Zhang, Bo Tian, Yan Bian, Wei Wang, Han Lin, Luo-Wei Wang
doi : 10.18632/aging.205495
Unveiling the potential of HSPA4: a comprehensive pan-cancer analysis of HSPA4 in diagnosis, prognosis, and immunotherapy
Junhao Yang, Xiaoxiao Wu, Jianhong You
doi : 10.18632/aging.205496
Identification and validation of an H2AZ1-based index model: a novel prognostic tool for hepatocellular carcinoma
Jiamin Gao, Qinchen Lu, Jialing Zhong, Zhijian Li, Lixin Pan, Chao Feng, Shaomei Tang, Xi Wang, Yuting Tao, Xianguo Zhou, Qiuyan Wang
doi : 10.18632/aging.205497
Integrative analysis confirms TPX2 as a novel biomarker for clinical implication, tumor microenvironment, and immunotherapy response across human solid tumors
Mingxia Zhu, Xiaping Wang, Qing Zhang, Chen Xie, Tongshan Wang, Kai Shen, Lan Zhang, Xin Zhou
doi : 10.18632/aging.205498
Prognostic model development and molecular subtypes identification in bladder urothelial cancer by oxidative stress signatures
Ying Dong, Xiaoqing Wu, Chaojie Xu, Yasir Hameed, Mostafa A. Abdel-Maksoud, Taghreed N. Almanaa, Mohamed H. Kotob, Wahidah H. Al-Qahtani, Ayman M. Mahmoud, William C. Cho, Chen Li
doi : 10.18632/aging.205499
A study on the role of Taxifolin in inducing apoptosis of pancreatic cancer cells: screening results using weighted gene co-expression network analysis
Shao-Jie Chen, Li-Kun Ren, Xiao-Bin Fei, Peng Liu, Xing Wang, Chang-Hao Zhu, Yao-Zhen Pan
doi : 10.18632/aging.205500
Serum metabolome and gut microbiome alterations are associated with low handgrip strength in older adults
Yan Guo, Qin Wang, Yifan Lv, Fan Xia, Xin Chen, Yan Mao, Xiaodong Wang, Guoxian Ding, Jing Yu
doi : 10.18632/aging.205501
Identification of an angiogenesis-related risk score model for survival prediction and immunosubtype screening in multiple myeloma
Manya Yu, Hongquan Ming, Mengting Xia, Jiaqi Fu, Zhiguo Cai, Xing Cui
doi : 10.18632/aging.205502
Underlying mechanisms of novel cuproptosis-related dihydrolipoamide branched-chain transacylase E2 (DBT) signature in sunitinib-resistant clear-cell renal cell carcinoma
Shiue-Wei Lai, Pei-Wei Weng, Vijesh Kumar Yadav, Narpati Wesa Pikatan, Chi-Tai Yeh, Ming-Shou Hsieh, Chu-Lin Chou
doi : 10.18632/aging.205504
MicroRNA-146a gene transfer ameliorates senescence and senescence-associated secretory phenotypes in tendinopathic tenocytes
Che-Chia Hsu, Shih-Yao Chen, Po-Yen Ko, Fa-Chuan Kwan, Wei-Ren Su, I-Ming Jou, Po-Ting Wu
doi : 10.18632/aging.205505
Integrated single-cell and bulk characterization of branched chain amino acid metabolism-related key gene BCAT1 and association with prognosis and immunogenicity of clear cell renal cell carcinoma
Jie Zheng, Yingqing Liu, Jiawei Wang, Jiewu Shi, Lin Li, Xuefeng Jiang, Lingsong Tao
doi : 10.18632/aging.205506
circ_0039787 promotes cervical cancer cell tumorigenesis by regulation of the miR-877-5p-KRAS axis
Xiuchao He, Jing Sun, Jing Zhang, Binbin Zhu, Lufei Jin, Jianhua Wang, Qingyan Guan
doi : 10.18632/aging.205508
Integrative analysis of single-cell and bulk RNA-sequencing data revealed disulfidptosis genes-based molecular subtypes and a prognostic signature in lung adenocarcinoma
Haixia Wang, Xuemei Zhu, Fangchao Zhao, Pengfei Guo, Jing Li, Jingfang Du, Guoyong Shan, Yishuai Li, Juan Li
doi : 10.18632/aging.205509
Machine learning-based B cell-related diagnostic biomarker signature and molecular subtypes characteristic of ulcerative colitis
Guo-Liang Wu, Li Li, Xiao-Yao Chen, Wei-Feng Zhang, Jun-Bo Wu, Xiaoning Yu, Hong-Jin Chen
doi : 10.18632/aging.205510
Targeting PERK-ATF4-P21 axis enhances the sensitivity of osteosarcoma HOS cells to Mppα-PDT
Shenxi Zhong, Ye Zhang, Hai Mou, Changchun Jian, Qiu Huang, Yunsheng Ou
doi : 10.18632/aging.205511
Construction of a necroptosis-related lncRNA signature for predicting prognosis and revealing the immune microenvironment in bladder cancer
Jingsong Wang, Zhengyu Jiang, Kai Wang, Qingyuan Zheng, Jun Jian, Xiuheng Liu, Zhiyuan Chen, Rui Yang, Lei Wang
doi : 10.18632/aging.205512
MicroRNA-124 negatively regulates STAT3 to alleviate hypoxic-ischemic brain damage by inhibiting oxidative stress
Jiaqing Geng, Jiangpeng Feng, Fangzi Ke, Fang Fang, Xiaoqi Jing, Jiaxin Tang, Chengzhi Fang, Binghong Zhang
doi : 10.18632/aging.205513
Mechanism of Erianin anti-triple negative breast cancer based on transcriptomics methods and network pharmacology
Ming Li, Yuan Zhao, Huimin Li, Shiyao Kang, Xuming Deng, Miaomiao Sheng
doi : 10.18632/aging.205516
Comprehensive analysis of cellular senescence and immune microenvironment in papillary thyroid carcinoma
Yinde Huang, Han Jiang, Guangwen Xu, Xin Li, Wenbin Chen, Yu Lun, Jian Zhang
doi : 10.18632/aging.205520
Identification of crucial anoikis-related genes as novel biomarkers and potential therapeutic targets for lung adenocarcinoma via bioinformatic analysis and experimental verification
Jie Wu, Yuting Zhang, Guoxing You, Wenjie Guo, Yupeng Wang, Jiaming Li, Rongzhi Tan, Xihua Fu, Yukuan Tang, Jie Zan, Jianfen Su
doi : 10.18632/aging.205521
Anoikis-related gene signature is associated with immune infiltration and predicts the prognosis of non-small cell lung cancer
Yixuan Wu, Zhou Zhou, Qianyi Qi, Shirong Xu, Lin Chen, Feng Wang
doi : 10.18632/aging.205522
Investigating the clinical role and prognostic value of genes related to insulin-like growth factor signaling pathway in thyroid cancer
Junyan Liu, Xin Miao, Jing Yao, Zheng Wan, Xiaodong Yang, Wen Tian
doi : 10.18632/aging.205524
Overexpression of SPP1 is a prognostic indicator of immune infiltration in lung adenocarcinoma
Binbin Li, Xue Li, Qingfeng Yang, Yiyang Jiang, Qianwen Zhang, Jingtao Zhang, Wenqiang Cui, Fei Xu
doi : 10.18632/aging.205526
Netrin-1 mitigates acute lung injury by preventing the activation of the Toll-like receptor 4/nuclear factor-κB (TLR4/NF-κB) signaling
Jian Su, Zhu Jian, Miao Zou, Huasheng Tong, Peng Wan
doi : 10.18632/aging.205527
Minocycline alleviates LPS-induced cognitive dysfunction in mice by inhibiting the NLRP3/caspase-1 pathway
Fenfang Zhan, Yao Dong, Lanqian Zhou, Xiaozhong Li, Zheng Zhou, Guohai Xu
doi : 10.18632/aging.205528
ITGB2 fosters the cancerous characteristics of ovarian cancer cells through its role in mitochondrial glycolysis transformation
Li Guo-Wei, Jin Yan-Ping, Qiu Jian-Ping, Lu Xiu-Fang
doi : 10.18632/aging.205529
Role of estrogen in treatment of female depression
Qihan Sun, Guangquan Li, Fangyi Zhao, Mengmeng Dong, Wei Xie, Qianqian Liu, Wei Yang, Ranji Cui
doi : 10.18632/aging.205507
Correction for: RNA-seq analysis of the key long noncoding RNAs and mRNAs related to cognitive impairment after cardiac arrest and cardiopulmonary resuscitation
Chan Chen, Changliang Liu, Zhendong Niu, Ming Li, Yuhan Zhang, Rui Gao, Hai Chen, Qiao Wang, Shu Zhang, Ronghua Zhou, Lu Gan, Zheng Zhang, Tao Zhu, Hai Yu, Jin Liu
doi : 10.18632/aging.205612
Correction for: Knockdown of TXNDC9 induces apoptosis and autophagy in glioma and mediates cell differentiation by p53 activation
Tingting Zheng, Keke Chen, Xue Zhang, Huanhuan Feng, Yu Shi, Li Liu, Jun Zhang, Yun Chen
doi : 10.18632/aging.205623
