Annals of Neurology




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Annals of Neurology: Volume 95, Number 2, February 2024

doi : 10.1002/ana.26688

Volume 95, Issue 2

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Biomarker Qualification for Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: Theory and Practice

Michael Benatar MD, PhD, Lyle W. Ostrow MD, PhD, Joseph W Lewcock PhD, Frank Bennett PhD, Jeremy Shefner MD, PhD, Robert Bowser PhD, Paul Larkin PhD, Lucie Bruijn PhD, Joanne Wuu ScM

doi : 10.1002/ana.26860

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Higher Glycemic Index and Glycemic Load Diet Is Associated with Slower Disease Progression in Amyotrophic Lateral Sclerosis

Ikjae Lee MD, MSc, Hiroshi Mitsumoto MD, Seonjoo Lee PhD, Edward Kasarskis MD, PhD, Michael Rosenbaum MD, Pam Factor-Litvak PhD, Jeri W. Nieves PhD

doi : 10.1002/ana.26825

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Disease-Modifying Drugs Extend Survival in Hereditary Transthyretin Amyloid Polyneuropathy

Mitsuharu Ueda MD, PhD, Yohei Misumi MD, PhD, Toshiya Nomura MD, PhD, Masayoshi Tasaki PhD, Shiori Yamakawa MD, Konen Obayashi MD, PhD, Taro Yamashita MD, PhD, Yukio Ando MD, PhD

doi : 10.1002/ana.26845

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Improving Early Recognition of Treatment-Responsive Causes of Rapidly Progressive Dementia: The STAM3P Score

Nihal Satyadev MD, MPH, Philip W. Tipton MD, Yuka Martens PhD, S. Richard Dunham MD, Michael D. Geschwind MD, PhD, FANA, John C. Morris MD, FAAN, Matthew R. Brier MD, PhD, Neill R. Graff-Radford MD, Gregory S. Day MD, MSc, MSCI

doi : 10.1002/ana.26812

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Regional Tau Deposition Reflects Different Pathways of Subsequent Neurodegeneration and Memory Decline in Cognitively Normal Older Adults

Xi Chen PhD, Tyler N. Toueg BS, Theresa M. Harrison PhD, Suzanne L. Baker PhD, William J. Jagust MD

doi : 10.1002/ana.26813

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Proteomic Indicators of Health Predict Alzheimer's Disease Biomarker Levels and Dementia Risk

Heather E. Dark PhD, Clare Paterson PhD, Gulzar N. Daya MS, Zhongsheng Peng MD, PhD, Michael R. Duggan PhD, Murat Bilgel PhD, Yang An PhD, Abhay Moghekar MBBS, Christos Davatzikos PhD, Susan M. Resnick PhD, Kelsey Loupy PhD, Missy Simpson PhD, Julián Candia PhD, Thomas Mosley PhD, Josef Coresh PhD, Priya Palta PhD, Luigi Ferrucci MD, PhD, Allison Shapiro PhD, MPH, Stephen A. Williams MD, PhD, Keenan A. Walker PhD

doi : 10.1002/ana.26817

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Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease

Lukai Zheng MD, MMed, Anna Rubinski PhD, Jannis Denecke MSc, Ying Luan MD, PhD, Ruben Smith MD, PhD, Olof Strandberg PhD, Erik Stomrud MD, PhD, Rik Ossenkoppele PhD, Diana Otero Svaldi PhD, Ixavier Alonzo Higgins PhD, Sergey Shcherbinin PhD, Michael J. Pontecorvo PhD, Oskar Hansson MD, PhD, Nicolai Franzmeier PhD, Michael Ewers PhD, for the Alzheimer's Disease Neuroimaging Initiative

doi : 10.1002/ana.26818

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Eligibility Rates among Racially and Ethnically Diverse US Participants in Phase 2 and Phase 3 Placebo-Controlled, Double-Blind, Randomized Trials of Lecanemab and Elenbecestat in Early Alzheimer Disease

Joshua D. Grill PhD, Charlene Flournoy MS, Shobha Dhadda PhD, Karin Ernstrom MS, Reisa Sperling MD, Doris Molina-Henry PhD, Kate Tranotti MBA, Russell Harris MBA, Michio Kanekiyo MS, Michelle Gee PhD, Michael Irizarry MD, Lynn Kramer MD, Paul Aisen PhD, Rema Raman PhD

doi : 10.1002/ana.26819

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Diagnostic Utility of Cerebrospinal Fluid Biomarkers in Patients with Rapidly Progressive Dementia

Lindsey A. Kuchenbecker BS, BA, Philip W. Tipton MD, Yuka Martens PhD, Matthew R. Brier MD, PhD, Nihal Satyadev MD, MPH, S. Richard Dunham MD, Evelyn B. Lazar MD, Maxwell V. Dacquel, Rachel L. Henson MS, Guojun Bu PhD, Michael D. Geschwind MD, PhD, FAAN, John C. Morris MD, FAAN, Suzanne E. Schindler MD, PhD, Elizabeth Herries BA, Neill R. Graff-Radford MD, FAAN, Gregory S. Day MD, MSc, MSCI, FAAN

doi : 10.1002/ana.26822

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Relative Contributions of Mixed Pathologies to Cognitive and Functional Symptoms in Brain Donors Exposed to Repetitive Head Impacts

Nicole Saltiel BA, Yorghos Tripodis PhD, Talia Menzin MS, Aliyah Olaniyan MS, Zach Baucom PhD, Eukyung Yhang BS, Joseph N. Palmisano MPH, MA, Brett Martin MS, Madeline Uretsky MS, Evan Nair BS, Bobak Abdolmohammadi BA, Arsal Shah BS, Raymond Nicks MS, Christopher Nowinski PhD, Robert C. Cantu MD, Daniel H. Daneshvar MD, PhD, Brigid Dwyer MD, Douglas I. Katz MD, Robert A. Stern PhD, Victor E. Alvarez MD, Bertrand Huber MD, PhD, Patricia A. Boyle PhD, Julie A. Schneider MD, MS, Jesse Mez MD, MS, Ann C. McKee MD, Michael L. Alosco PhD, Thor D. Stein MD, PhD

doi : 10.1002/ana.26823

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Deep Resequencing of the 1q22 Locus in Non-Lobar Intracerebral Hemorrhage

Livia Parodi PhD, Mary E. Comeau MA, Marios K. Georgakis MD, PhD, Ernst Mayerhofer MD, Jaeyoon Chung PhD, Guido J. Falcone MD, ScD, MPH, Rainer Malik PhD, Stacie L. Demel PhD, Bradford B. Worrall MD, MSc, Sebastian Koch MD, Fernando D. Testai MD, PhD, Steven J. Kittner MD, Jacob L. McCauley PhD, Christiana E. Hall MD, MS, Douglas J. Mayson MD, Mitchell S.V. Elkind MD, MS, Michael L. James MD, Daniel Woo MD, Jonathan Rosand MD, MSc, Carl D. Langefeld PhD, Christopher D. Anderson MD, MMSc

doi : 10.1002/ana.26814

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Association of the Timing of Atrial Fibrillation Detection and Insular Involvement With the Risk of Embolic Events After Acute Ischemic Stroke

Keisuke Tokunaga MD, PhD, Kazunori Toyoda MD, PhD, Shunsuke Kimura MD, Kazuo Minematsu MD, PhD, Masahiro Yasaka MD, PhD, Yasushi Okada MD, PhD, Sohei Yoshimura MD, PhD, Masatoshi Koga MD; PhD, on behalf of the SAMURAI-NVAF and RELAXED investigators

doi : 10.1002/ana.26815

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Strokes Averted by Intravenous Thrombolysis: A Secondary Analysis of a Prospective, Multicenter, Controlled Trial of Mobile Stroke Units

Babak B. Navi MD, MS, RPNI, Ivo Bach MD, Alexandra L. Czap MD, Mengxi Wang PhD, Jose-Miguel Yamal PhD, Asha P. Jacob MD, MPH, Stephanie A. Parker MHA, RN, Suja S. Rajan PhD, Saad Mir MD, Carla Sherman RN, Joshua Z. Willey MD, Jeffrey L. Saver MD, Michael O. Gonzalez MS, Noopur Singh MPH, William J. Jones MD, David Ornelas RN, Nicole R. Gonzales MD, Anne W. Alexandrov PhD, Andrei V. Alexandrov MD, May Nour MD, PhD, Ilana Spokoyny MD, Jason Mackey MD, Sarah Q. Collins BSN, RN, Kelly Silnes MS, Mathew E. Fink MD, Joey English MD, PhD, Nobl Barazangi MD, PhD, Patti L. Bratina RN, Jay Volpi MD, Chethan P. V. Rao MD, Laura Griffin DNP, David Persse MD, James C. Grotta MD … See fewer authors

doi : 10.1002/ana.26816

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Endovascular Thrombectomy for a Progressive Stroke Patient With a High-Burden Carotid Free-Floating Thrombus

Zhikai Hou MD, PhD, Rongrong Cui MD, Ying Yu MD, Ning Ma MD

doi : 10.1002/ana.26820

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De novo variants in KCNA3 cause developmental and epileptic encephalopathy

Maria Virginia Soldovieri PhD, Paolo Ambrosino PhD, Ilaria Mosca PhD, Ilenio Servettini PhD, Francesca Pietrunti MSc, Giorgio Belperio Msc, KCNA3 study group, Steffen Syrbe MD, Maurizio Taglialatela MD, PhD, Johannes R Lemke MD

doi : 10.1002/ana.26826

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Determinants of Functional Outcome after Pediatric Hemispherotomy

Georgia Ramantani MD, PhD, Dorottya Cserpan PhD, Martin Tisdall MD, Willem M. Otte PhD, Georg Dorfmüller MD, PhD, J. Helen Cross MD, PhD, Monique van Schooneveld PhD, Pieter van Eijsden MD, Frauke Nees PhD, Gitta Reuner MD, PhD, Niklaus Krayenbühl MD, PhD, Josef Zentner MD, PhD, Christine Bulteau MD, PhD, Kees P. J. Braun MD, PhD

doi : 10.1002/ana.26830

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Hippocampal Perfusion Affects Motor and Cognitive Functions in Parkinson Disease: An Early Phase 18F-FP-CIT Positron Emission Tomography Study

Min Young Chun MD, PhD, Seok Jong Chung MD, PhD, Su Hong Kim MD, PhD, Chan Wook Park MD, Seong Ho Jeong MD, Hye Sun Lee PhD, Phil Hyu Lee MD, PhD, Young H. Sohn MD, PhD, Yong Jeong MD, PhD, Yun Joong Kim MD, PhD

doi : 10.1002/ana.26827

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Stage-Dependent Biomarker Changes in Spinocerebellar Ataxia Type 3

Jennifer Faber MD, Moritz Berger PhD, Carlo Wilke MD, Jeannette Hubener-Schmid PhD, Tamara Schaprian MSc, Magda M. Santana PhD, Marcus Grobe-Einsler MD, Demet Onder MD, Berkan Koyak MD, Paola Giunti MD, Hector Garcia-Moreno MD, Cristina Gonzalez-Robles MD, Manuela Lima PhD, Mafalda Raposo PhD, Ana Rosa Vieira Melo MSc, Luís Pereira de Almeida PhD, Patrick Silva MSc, Maria M. Pinto MSc, Bart P. van de Warrenburg MD, PhD, Judith van Gaalen MD, Jeroen de Vries MD, Gulin Oz PhD, James M. Joers PhD, Matthis Synofzik MD, Ludger Schols MD, Olaf Riess MD, Jon Infante MD, Leire Manrique MD, Dagmar Timmann MD, Andreas Thieme MD, Heike Jacobi MD, Kathrin Reetz MD, Imis Dogan PhD, Chiadikaobi Onyike MD, Michal Povazan PhD, Jeremy Schmahmann MD, Eva-Maria Ratai PhD, Matthias Schmid PhD, Thomas Klockgether MD

doi : 10.1002/ana.26824

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Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids: A Potentially Overlooked Diagnosis

Athanasios Tsibonakis MD, Aikaterini Theodorou MD, Penelope Korkolopoulou MD, Georgios Tsivgoulis MD

doi : 10.1002/ana.26821

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A Letter Concerning a Role for Blood–Brain Barrier Dysfunction in Delirium following Noncardiac Surgery in Older Adults

Loic Le Guennec, Alexander Balcerac, Nicolas Weiss

doi : 10.1002/ana.26837

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Reply to “A Letter Concerning a Role for Blood–Brain Barrier Dysfunction in Delirium following Noncardiac Surgery in Older Adults�

Michael J. Devinney MD, PhD, Miles Berger MD, PhD

doi : 10.1002/ana.26834

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Chance Bias Arising from TSC2 Mutation Imbalance in the PREVeNT Trial

Debopam Samanta MD

doi : 10.1002/ana.26855

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Reply to “Chance Bias Arising from TSC2 Mutation Imbalance in the PREVeNT Trial�

E. Martina Bebin MD, MPA

doi : 10.1002/ana.26857

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Myelin Oligodendrocyte Glycoprotein Antibody-Positive Patients Meeting the 2017 McDonald Criteria for Multiple Sclerosis: Challenges in Diagnosis and Treatment Decisions

Sohyeon Kim MD, Mi-Yeon Eun MD, Jae-Joon Lee MD, Hung Youl Seok MD

doi : 10.1002/ana.26859

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Reply to “Myelin Oligodendrocyte Glycoprotein Antibody-Positive Patients Meeting the 2017 McDonald Criteria for Multiple Sclerosis: Challenges in Diagnosis and Treatment Decisions�

Javier Villacieros-Ã�lvarez MD, Carmen Espejo PhD, Ã�lvaro Cobo-Calvo MD, PhD

doi : 10.1002/ana.26856

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Correction to Lyden P, Pryor KE, Coffey CS, et al. Final results of the RHAPSODY trial: a multi-center, phase 2 trial using a continual reassessment method to determine the safety and tolerability of 3K3A-APC, a recombinant variant of human activated protein C, in combination with tissue plasminogen activator, mechanical thrombectomy or both in moderate to severe acute ischemic stroke. Ann Neurol 2019;85:125–136.

doi : 10.1002/ana.26841

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