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Efficacy and safety of the traditional herbal medication Chai-Ling-Tang (in China), Siryung-tang (in Republic of Korea) or Sairei-To (in Japan)
Christian Bailly
doi : 10.1016/j.jep.2023.117127
Volume 319, Part 1, 30 January 2024, 117127
Review of traditional uses, phytochemistry and pharmacology of Tibetan Medicine tangchong
Tianru Wang a,1, Qiuyue Li b,1, Ziyu Zhou a, Jia Liu c, Yiwen Tao a, Yi Zhang c, Yong Zeng a,***, Sanyin Zhang c,**, Jinsong Su
doi : 10.1016/j.jep.2023.117129
Volume 319, Part 1, 30 January 2024, 117129
Traditional uses, phytochemistry, pharmacology, applications, and quality control of Gastrodia elata Blume: A comprehensive review
Meng-qi Gong , Fei-fan Lai , Jian-zhen Chen , Xiao-hong Li , Ya-jie Chen , Yu He
doi : 10.1016/j.jep.2023.117128
Volume 319, Part 1, 30 January 2024, 117128
Saponins derived from Gynostemma pentaphyllum regulate triglyceride and cholesterol metabolism and the mechanisms: A review
Peng Xie , Hao-Tian Luo , Wen-Jing Pei , Man-Yu Xiao , Fang-Fang Li , Yu-Long Gu **, Xiang-Lan Piao
doi : 10.1016/j.jep.2023.117186
Volume 319, Part 1, 30 January 2024, 117186
Efficacy and potential mechanisms of the main active ingredients of astragalus mongholicus in animal models of liver fibrosis: A systematic review and meta-analysis
Lijuan Dan a,1, Yanwei Hao b,1, Hongfei Song a, Tianyuan Wang c, Jia Li a, Xiaoyan He a, Yue Su
doi : 10.1016/j.jep.2023.117198
Volume 319, Part 1, 30 January 2024, 117198
An integrated strategy for rapid discovery and identification of the potential effective fragments of polysaccharides from Saposhnikoviae Radix
Jie Li a, Meng Sun a, Chang Xu a, Chang Zhou a, Shu-jin Jing a, Yan-yan Jiang a,b,**, Bin Liu
doi : 10.1016/j.jep.2023.117099
Volume 319, Part 1, 30 January 2024, 117099
Antidiabetic effects of polyherbal mixture made of Centaurium erythraea, Cichorium intybus and Potentilla erecta
Aleksandra Petrovi´c a,*, Vi?snja Madi´c a, Gordana Stojanovi´c b, Ivana Zlatanovi´c b, Bojan Zlatkovi´c a, Perica Vasiljevi´c a, Ljubi?sa ?or?evi´c
doi : 10.1016/j.jep.2023.117032
Volume 319, Part 1, 30 January 2024, 117032
Identifying hepatoprotective mechanism and effective components of Yinchenzhufu decoction in chronic cholestatic liver injury using a comprehensive strategy based on metabolomics, molecular biology, pharmacokinetics, and cytology
Yuanyuan Li a,1, Xiaotian Peng a,1, Guofeng Wang a,1, Bin Zan a, Yahang Wang a, Juan Zou a, Tian Tian a, Qian Meng a, Rong Shi a, Tianming Wang a, Jiasheng Wu a,**, Yueming Ma
doi : 10.1016/j.jep.2023.117060
Volume 319, Part 1, 30 January 2024, 117060
Spectrum–effect relationship combined with bioactivity evaluation to discover the main anxiolytic active components of Baihe Dihuang decoction
Lin Tang a,1, Hong-Qing Zhao b,1, Hui Yang a, Chao Hu a, Si-jing Ma c, Wang-Zhong Xiao a, Yu-hui Qing b, Lei Yang a, Rong-Rong Zhou c,*, Jian Liu a,**, Shui-Han Zhang
doi : 10.1016/j.jep.2023.117090
Volume 319, Part 1, 30 January 2024, 117090
Efficacy and potential therapeutic mechanism of Weiwei decoction on Spasmolytic polypeptide-expressing metaplasia in Helicobacter pylori-infected and Atp4a-knockout mice
Xinxin Hong a,1, Haiwen Li a,1, Yandan Lin b, Liuru Luo b, Weijun Xu a, Jianyuan Kang a, Jingwei Li a, Bin Huang a, Yifei Xu a, Huafeng Pan c,**, Shaoju Guo
doi : 10.1016/j.jep.2023.117062
Volume 319, Part 1, 30 January 2024, 117062
Ginsenoside Rg1 alleviates ANIT-induced cholestatic liver injury by inhibiting hepatic inflammation and oxidative stress via SIRT1 activation
Qianyan Gao a, Guodong Li a, Yue Zu a, Yanjiao Xu a, Congyi Wang b, Dong Xiang a, Wenxi He a, Tianze Shang a, Xinwei Cheng a, Dong Liu a,*, Chengliang Zhang
doi : 10.1016/j.jep.2023.117089
Volume 319, Part 1, 30 January 2024, 117089
Isomaculosidine facilitates NLRP3 inflammasome activation by promoting mitochondrial reactive oxygen species production and causes idiosyncratic liver injury
Wei Shi a,b,c,1, Tingting Liu c,e,1, Huijie Yang a,1, Jia Zhao c, Ziying Wei a, Yujiao Huang a, Zhiyong Li b, Hui Li a, Longxin Liang c, Xiaorong Hou c, Yuanyuan Chen c, Yuan Gao b,***, Zhaofang Bai c,d,**, Xiaohe Xiao c
doi : 10.1016/j.jep.2023.117063
Volume 319, Part 1, 30 January 2024, 117063
Gardenia extract protects against intrahepatic cholestasis by regulating bile acid enterohepatic circulation
Shasha Qin a,1, Jingzhuo Tian a,1, Yong Zhao a, Lianmei Wang a, Jinyu Wang b, Suyan Liu a, Jing Meng a, Fang Wang a, Chenyue Liu a, Jiayin Han a, Chen Pan a, Yushi Zhang a, Yan Yi a, Chunying Li a, Meiting Liu a, Aihua Liang
doi : 10.1016/j.jep.2023.117083
Volume 319, Part 1, 30 January 2024, 117083
Optimal compatibility proportional screening of Trichosanthis Pericarpium - Trichosanthis Radix and its anti - Inflammatory components effect on experimental zebrafish and coughing mice
Pei Liu a,*,1, Xiao-ying Tan a,1, Huang-qin Zhang a,b, Ke-lei Su b, Er-xin Shang a, Qing-ling Xiao b, Sheng Guo a, Jin-ao Duan
doi : 10.1016/j.jep.2023.117096
Volume 319, Part 1, 30 January 2024, 117096
High-resolution neuraminidase inhibition profiling of Arnebia euchroma (Royle) I.M. Johnst. based on HR-MS and target isolation: An example study of anti-infectious constituents in traditional Chinese medicine
Yuheng Huang a,1, Xiaoxin Guo a,1, Zhen Wang a,1, Cong Yin d, Mu Chen a, Jiaming Xie a, Ning Li c, Zhengchao Tu a, Juan Li d, Jiaqing Cao a, Zhengjin Jiang a, Weihuan Huang b,**, Haiyan Tian
doi : 10.1016/j.jep.2023.117074
Volume 319, Part 1, 30 January 2024, 117074
The effect and mechanism of Qingre Huashi formula in the treatment of chronic hepatitis B with Gan-dan-shi-Re syndrome: An integrated transcriptomic and targeted metabolomic analysis
Yiyu Lu a,1, Chaoqun Zhao b,1, Chengbao Wang c, Hong Cai d, Yuting Hu a, Long Chen b, Shanghai Yu b, Huiming Zhu f, Ping Liu b, Wang Wan’e e,2,*, Hua Zhang
doi : 10.1016/j.jep.2023.117092
Volume 319, Part 1, 30 January 2024, 117092
Anticholinesterase and antioxidant activity of Drynaria quercifolia and its ameliorative effect in scopolamine-induced memory impairment in mice
Rafia Ferdous a, Md. Badrul Islam b, Md. Yusuf Al-Amin a, Anik Kumar Dey a, Md. Omar Ali Mondal c, Md. Nurul Islam d, AHM Khurshid Alam a, Aziz Abdur Rahman a, Md. Golam Sadik
doi : 10.1016/j.jep.2023.117095
Volume 319, Part 1, 30 January 2024, 117095
Isolation of indole alkaloids and a new norneolignan of hydroethanol extract from the stem barks of Aspidosperma nitidum Benth: Preclinical evaluation of safety and anti-inflammatory and healing properties
Manoela Torres-Rˆego a,c, Patr?cia Coelho do Nascimento Nogueira b, Sarah Pollyana Dias dos Santos a, Alessandra Daniele-Silva c, Felipe França Cavalcanti a,c, Cinthya Iamile Frithz Brand?ao de Oliveira d, Hugo Alexandre Oliveira Rocha e, Matheus de Freitas Fernandes-Pedrosa c, Edilberto Rocha Silveira b, Renata Mendonça Ara?jo
doi : 10.1016/j.jep.2023.117076
Volume 319, Part 1, 30 January 2024, 117076
Hypericum roeperianum bark extract suppresses breast cancer proliferation via induction of apoptosis, downregulation of PI3K/Akt/mTOR signaling cascade and reversal of EMT
Michel-Gael F. Guefack a,b, Debojit Talukdar a, Rimi Mukherjee a, Subhabrata Guha a, Debarpan Mitra a, Depanwita Saha a, Gaurav Das a, François Damen c, Victor Kuete b,**, Nabendu Murmu
doi : 10.1016/j.jep.2023.117093
Volume 319, Part 1, 30 January 2024, 117093
Xihuang pill ameliorates colitis in mice by improving mucosal barrier injury and inhibiting inflammatory cell filtration through network regulation
Meng-Lei Hu a,b,c,d,e,f, Qian-Zan Liao a,b,c,d,e,f, Bo-Tong Liu a,b,c,d,e,f, Kai Sun b,c,d,e, f, Chun-Shui Pan b,c,d,e,f, Xiao-Yi Wang a,b,c,d,e,f, Li Yan b,c,d,e,f, Xin-Mei Huo a,b,c,d,e,f , Xian-Qun Zheng a,b,c,d,e,f, Yuan Wang g, Li-Jun Zhong h, Jian Liu a,c,d,e,f, Lin He a,c,d,e,f,**, Jing-Yan Han
doi : 10.1016/j.jep.2023.117098
Volume 319, Part 1, 30 January 2024, 117098
Study on quality difference between Belamcanda chinensis (L.) DC and Iris tectorum Maxim. based on chemical chromatogram analysis, biological activity evaluation and in vivo distribution rule
Hao Xiong a, Yuanfeng Yang a, Wenhui Guo a, Jinbin Yuan a, Wuliang Yang a,**, Meng Gao
doi : 10.1016/j.jep.2023.117091
Volume 319, Part 1, 30 January 2024, 117091
The protective role of Achyranthes aspera extract against cisplatin-induced nephrotoxicity by alleviating oxidative stress, inflammation, and PANoptosis
Song-Yi Lin a, Chia-Lin Chang d,e,f, Kuo-Tong Liou b,h,i, Yao-Kai Kao a, Yea-Hwey Wang c, Cher-Chia Chang g, Terry B.J. Kuo a, Hung-Tse Huang b, Cheryl C.H. Yang a,**, Chia-Ching Liaw b,***, Yuh-Chiang Shen
doi : 10.1016/j.jep.2023.117097
Volume 319, Part 1, 30 January 2024, 117097
Preliminary study on the material basis and mechanism underlying uric acid reduction by Thlaspi arvense L.
Xiumei Ke a,1, Xuan Yang b,1, Chao Hou b, Yunhong Wang c, YiFei Zhou b, Tongxuan Wu d, Rongping Yang b,*
doi : 10.1016/j.jep.2023.116814
Volume 319, Part 1, 30 January 2024, 116814
The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway
Liu Zhou , Yifei Yang , Xiaotong Fu , Bing Xia , Chun Li , Chenna Lu , Ying Qi , Haijing Zhang *, Ting Liu
doi : 10.1016/j.jep.2023.117100
Volume 319, Part 1, 30 January 2024, 117100
The therapeutic principle of combined clearing heat and resolving toxin plus TACE on primary liver cancer: A systematic review and meta-analysis
Yuyao Wang d,1, Wanfu Lin c, Guokai Huang c, Shuchang Nie c, Qin Yu a, Fenggang Hou b,**, Shaoqi Zong
doi : 10.1016/j.jep.2023.117072
Volume 319, Part 1, 30 January 2024, 117072
Effects and mechanism of extracts rich in phenylpropanoids-polyacetylenes and polysaccharides from Codonopsis Radix on improving scopolamine-induced memory impairment of mice
Qi Xie , Xianrun Hu , Xiang Zhao , Zedong Xiang , Qianping Chen , Zhejun Xie , Hanxue Wang , Yonglin Zhao , Xuemei Cheng , Changhong Wang
doi : 10.1016/j.jep.2023.117106
Volume 319, Part 1, 30 January 2024, 117106
Extract of Astragali Radix and Solanum nigrum Linne regulates microglia and macrophage polarization and inhibits the growth and infiltration of C6 glioblastoma
Mingxue Shen a, Suo Liu a, Qin Wei a, Xiong Zhang a, Shiyu Wen a, Runze Qiu a,**, Yingbin Li b,***, Hongwei Fan
doi : 10.1016/j.jep.2023.117067
Volume 319, Part 1, 30 January 2024, 117067
Analysis of pharmacodynamic components, targets and synergistic action mechanism of Fuyuan Shenghua granule for the treatment of medical-induced incomplete abortion based on network pharmacology
Qi-qiang Zhang a,1, Xue-mei Di a,b,1, Xiang Cao a, Yonghong Nie b, Wen Shuai b, Jun Li c,**, Hai Zhang
doi : 10.1016/j.jep.2023.117118
Volume 319, Part 1, 30 January 2024, 117118
Naoxueshu oral liquid promotes hematoma absorption by targeting CD36 in M2 microglia via TLR4/MyD88/NF-κB signaling pathway in rats with intracerebral hemorrhage
Ruoqi Li a, Meiying Song a, Yingyi Zheng a, Jiaxue Zhang a, Shanshan Zhang a, Xiang Fan a,b,
doi : 10.1016/j.jep.2023.117116
Volume 319, Part 1, 30 January 2024, 117116
Diuretic activity evaluation and chemical composition analysis of Hedyotis scandens extract from Mizoram, India, in rat models
Elizabeth Vanlalruati Ngamlai a, R.B. Pradhan a, P.C. Lalbiaknii a, Vanlalhruaii Ralte b,*, F. Lalnunmawia a, P.C. Vanlalhluna b, S.K. Mehta
doi : 10.1016/j.jep.2023.117079
Volume 319, Part 1, 30 January 2024, 117079
Juvenile toxicity study of deer antler extract in rats
Jinsoo Lee a,b, Byung-Cheol Han c, Woojin Kim a, Seung-Hyuk Shin d, Ji-Seong Jeong a, Quah Yixian a, Wook-Joon Yu
Quantitative proteomics based bioactive proteins discovery and quality control of medicinal leeches
Fu-Gui Li a, Xin-Yue Shi a, Liu Yang a, Xu Lu a, Yan Qi b, Ping Li a,***, Hua Yang a,**, Wen Gao
doi : 10.1016/j.jep.2023.117117
Volume 319, Part 1, 30 January 2024, 117117
Sceletium tortuosum-derived mesembrine significantly contributes to the anxiolytic effect of Zembrin®, but its anti-depressant effect may require synergy of multiple plant constituents
doi : 10.1016/j.jep.2023.117113
Volume 319, Part 1, 30 January 2024, 117113
Effects and mechanism of Kedaling tablets for atherosclerosis treatment based on network pharmacology, molecular docking and experimental study
doi : 10.1016/j.jep.2023.117108
Volume 319, Part 1, 30 January 2024, 117108
Multimodal investigation reveals the neuroprotective mechanism of Angong Niuhuang pill for intracerebral hemorrhage: Converging bioinformatics, network pharmacology, and experimental validation
doi : 10.1016/j.jep.2023.117045
Volume 319, Part 1, 30 January 2024, 117045
Chemical profiling of Shengmai injection, tissue distribution and pharmacokinetic characteristics of ginsenosides after intravenous dosing Shengmai injection in rats with cerebral ischemia
Huanhuan Wang a,c,1, Liying Tang a,1, Shaowei Hu a,1, Xixian Kong a, Yi Ouyang a, Dong Zhang a, Yi Zhang a, Shihuan Tang a, Hongwei Wu a,*, Hongjun Yang
doi : 10.1016/j.jep.2023.117119
Volume 319, Part 1, 30 January 2024, 117119
Based on spinal central sensitization creating analgesic screening approach to excavate anti-neuropathic pain ingredients of Corydalis yanhusuo W.T.Wang
Meng-Yuan Zhou a,1, Chang-Heng Yao a,1, Yu-Jie Yang a, Xue Li a, Jin Yang a, Ji-Hua Liu a,b,**, Bo-Yang Yu a,b,***, Wen-Ling Dai
doi : 10.1016/j.jep.2023.117084
Volume 319, Part 1, 30 January 2024, 117084
Neuroprotective mechanisms of defatted walnut powder against scopolamine-induced Alzheimer's disease in mice revealed through metabolomics and proteomics analyses
Xiajing Xu a, Yong Ding a, Meihan Liu a, Xuanmeng Zhang a, Dongmei Wang b, Yingni Pan a, Shumeng Ren a,*, Xiaoqiu Liu
doi : 10.1016/j.jep.2023.117107
Volume 319, Part 1, 30 January 2024, 117107
Revealing the mechanism of Zanthoxylum armatum DC. extract-induced liver injury in mice based on lipidomics
Nannan Yang a, Jian Zhang a, Jiafu Guo a, Qiwen Xiang a, Yan Huang b, Jiayu Wen a, Qiuyan Liu a, Tingting Hu a, Yan Chen a,b,*, Chaolong Rao
doi : 10.1016/j.jep.2023.117086
Volume 319, Part 1, 30 January 2024, 117086
Hyperglycemia effect of Pinctada martensii hydrolysate in diabetic db/db mice
Jiayun Li a,b,c,1, Yuanqing Wei a,b,c,1, Siying Huang a,b,c, Shenghan Yan f, Binyuan Zhao f, Xinzhi Wang b,c, Jipeng Sun g, Tianbao Chen e,h, Yueyang Lai d,**, Rui Liu
doi : 10.1016/j.jep.2023.117104
Volume 319, Part 1, 30 January 2024, 117104
Jianpi Shengqing Huazhuo Formula improves abnormal glucose and lipid metabolism in obesity by regulating mitochondrial biogenesis
Wenkai Wang a,b, Shanshan Chen a,b, Shuting Xu a,b, Guangyi Liao a,b, Weihao Li a,b, Xiao Yang a,b, Tingting Li a,b, Huifen Zhang c, Huanhuan Huang c, Yuqing Zhou c, Huafeng Pan a,b, Chuanquan Lin a,b,*
doi : 10.1016/j.jep.2023.117102
Volume 319, Part 1, 30 January 2024, 117102
Zhisou powder displays therapeutic effect on chronic bronchitis through inhibiting PI3K/Akt/HIF-1α/VEGFA signaling pathway and reprograming metabolic pathway of arachidonic acid
Yahui Dong a, Yang Liu a, Jie Tang b, Jiahui Du a, Xuzhen Zhuang a, Song Tan a, Ye Yang a,c,d,**, Dengke Yin
doi : 10.1016/j.jep.2023.117110
Volume 319, Part 1, 30 January 2024, 117110
An Andrographis paniculata Burm. Nees extract standardized for three main Andrographolides prevents house dust mite-induced airway inflammation, remodeling, and hyperreactivity by regulating Th1/Th2 gene expression in mice
Ibrahim Sulaiman a,1, Emmanuel Oshiogwe Okwuofu a, Norhafizah Mohtarrudin b, Jonathan Chee Woei Lim a, Johnson Stanslas
doi : 10.1016/j.jep.2023.117082
Volume 319, Part 1, 30 January 2024, 117082
A novel strategy of integrating network pharmacology and transcriptome reveals antiapoptotic mechanisms of Buyang Huanwu Decoction in treating intracerebral hemorrhage
Menghan Cheng a,c,d,e, Teng Li a,b,c,d,e, En Hu a,b,c,d,e, Qiuju Yan a,c,d,e, Haigang Li f, Yang Wang a,b,c,d,e, Jiekun Luo a,b,c,d,e, Tao Tang
doi : 10.1016/j.jep.2023.117123
Volume 319, Part 1, 30 January 2024, 117123
Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-κB trajectories
Nermeen B. Ali a, Sherihan Salaheldin Abdelhamid Ibrahim b, Muhammad A. Alsherbiny a,c,d, Eman Sheta e, Riham A. El-Shiekh a,*, Rehab M. Ashour a, Amira A. El-Gazar f, Ghada M. Ragab g, Sabah H. El-Gayed a,h, Chun Guang Li d, Essam Abdel-Sattar
doi : 10.1016/j.jep.2023.117115
Volume 319, Part 1, 30 January 2024, 117115
Taraxacum coreanum Nakai extract attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier dysfunction in Caco-2Â cells
Seok Hee Han a, Hak-Dong Lee b, Sanghyun Lee b,c,**, Ah Young Lee
doi : 10.1016/j.jep.2023.117105
Volume 319, Part 1, 30 January 2024, 117105
Polygonum cuspidatum Sieb. et Zucc. Extracts improve sepsis-associated acute kidney injury by inhibiting NF-κB-mediated inflammation and pyroptosis
Yuan Yang a,1, Jia Xu a,1, Jie Tu b,1, Yi Sun c, Cong Zhang c, Zhenpeng Qiu c,d,*, Han Xiao a
doi : 10.1016/j.jep.2023.117101
Volume 319, Part 1, 30 January 2024, 117101
Buyang Huanwu Decoction alleviates blood stasis, platelet activation, and inflammation and regulates the HMGB1/NF-κB pathway in rats with pulmonary fibrosis
Yuenan Feng a,1, Linfeng Dai b,1, Yanli Zhang a,1, Simiao Sun c,1, Shan Cong d,1, Shuang Ling e, Huan Zhang
doi : 10.1016/j.jep.2023.117088
Volume 319, Part 1, 30 January 2024, 117088
Gypenoside XVII inhibits ox-LDL-induced macrophage inflammatory responses and promotes cholesterol efflux through activating the miR-182-5p/HDAC9 signaling pathway
Wen-Yi Deng a,1, Cheng-Long Zhou b,1, Meng-Ya Zeng
doi : 10.1016/j.jep.2023.117070
Volume 319, Part 1, 30 January 2024, 117070
Hyperglycemia effect of Pinctada martensii hydrolysate in diabetic db/db mice
Jiayun Li a,b,c,1, Yuanqing Wei a,b,c,1, Siying Huang a,b,c, Shenghan Yan f, Binyuan Zhao f, Xinzhi Wang b,c, Jipeng Sun g, Tianbao Chen e,h, Yueyang Lai d,**, Rui Liu
doi : 10.1016/j.jep.2023.117104
Volume 319, Part 1, 30 January 2024, 117104
Jianpi Shengqing Huazhuo Formula improves abnormal glucose and lipid metabolism in obesity by regulating mitochondrial biogenesis
Wenkai Wang a,b, Shanshan Chen a,b, Shuting Xu a,b, Guangyi Liao a,b, Weihao Li a,b, Xiao Yang a,b, Tingting Li a,b, Huifen Zhang c, Huanhuan Huang c, Yuqing Zhou c, Huafeng Pan a,b, Chuanquan Lin a,b,*
doi : 10.1016/j.jep.2023.117102
Volume 319, Part 1, 30 January 2024, 117102
Zhisou powder displays therapeutic effect on chronic bronchitis through inhibiting PI3K/Akt/HIF-1α/VEGFA signaling pathway and reprograming metabolic pathway of arachidonic acid
Yahui Dong a, Yang Liu a, Jie Tang b, Jiahui Du a, Xuzhen Zhuang a, Song Tan a, Ye Yang a,c,d,**, Dengke Yin
doi : 10.1016/j.jep.2023.117110
Volume 319, Part 1, 30 January 2024, 117110
An Andrographis paniculata Burm. Nees extract standardized for three main Andrographolides prevents house dust mite-induced airway inflammation, remodeling, and hyperreactivity by regulating Th1/Th2 gene expression in mice
Ibrahim Sulaiman a,1, Emmanuel Oshiogwe Okwuofu a, Norhafizah Mohtarrudin b, Jonathan Chee Woei Lim a, Johnson Stanslas
doi : 10.1016/j.jep.2023.117082
Volume 319, Part 1, 30 January 2024, 117082
A novel strategy of integrating network pharmacology and transcriptome reveals antiapoptotic mechanisms of Buyang Huanwu Decoction in treating intracerebral hemorrhage
Menghan Cheng a,c,d,e, Teng Li a,b,c,d,e, En Hu a,b,c,d,e, Qiuju Yan a,c,d,e, Haigang Li f, Yang Wang a,b,c,d,e, Jiekun Luo a,b,c,d,e, Tao Tang
doi : 10.1016/j.jep.2023.117123
Volume 319, Part 1, 30 January 2024, 117123
Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-κB trajectories
Nermeen B. Ali a, Sherihan Salaheldin Abdelhamid Ibrahim b, Muhammad A. Alsherbiny a,c,d, Eman Sheta e, Riham A. El-Shiekh a,*, Rehab M. Ashour a, Amira A. El-Gazar f, Ghada M. Ragab g, Sabah H. El-Gayed a,h, Chun Guang Li d, Essam Abdel-Sattar
doi : 10.1016/j.jep.2023.117115
Volume 319, Part 1, 30 January 2024, 117115
Taraxacum coreanum Nakai extract attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier dysfunction in Caco-2Â cells
Seok Hee Han a, Hak-Dong Lee b, Sanghyun Lee b,c,**, Ah Young Lee
doi : 10.1016/j.jep.2023.117105
Volume 319, Part 1, 30 January 2024, 117105
Polygonum cuspidatum Sieb. et Zucc. Extracts improve sepsis-associated acute kidney injury by inhibiting NF-κB-mediated inflammation and pyroptosis
Yuan Yang a,1, Jia Xu a,1, Jie Tu b,1, Yi Sun c, Cong Zhang c, Zhenpeng Qiu c,d,*, Han Xiao a
doi : 10.1016/j.jep.2023.117101
Volume 319, Part 1, 30 January 2024, 117101
Buyang Huanwu Decoction alleviates blood stasis, platelet activation, and inflammation and regulates the HMGB1/NF-κB pathway in rats with pulmonary fibrosis
Yuenan Feng a,1, Linfeng Dai b,1, Yanli Zhang a,1, Simiao Sun c,1, Shan Cong d,1, Shuang Ling e, Huan Zhang
doi : 10.1016/j.jep.2023.117088
Volume 319, Part 1, 30 January 2024, 117088
Gypenoside XVII inhibits ox-LDL-induced macrophage inflammatory responses and promotes cholesterol efflux through activating the miR-182-5p/HDAC9 signaling pathway
Wen-Yi Deng a,1, Cheng-Long Zhou b,1, Meng-Ya Zeng
doi : 10.1016/j.jep.2023.117070
Volume 319, Part 1, 30 January 2024, 117070
Bombyx batryticatus extract activates coagulation factor â…« to promote angiogenesis in rats with cerebral ischemia/reperfusion injury
doi : 10.1016/j.jep.2023.117081
Volume 319, Part 1, 30 January 2024, 117081
Yi Mai granule improve energy supply of endothelial cells in atherosclerosis via miRNA-125a-5p regulating mitochondrial autophagy through Pink1-Mfn2-Parkin pathway
doi : 10.1016/j.jep.2023.117114
Volume 319, Part 1, 30 January 2024, 117114
Identification of bioactive components on antihemorrhoidal activity of Cistus laurifolius L. using RP-HPLC and LC-QTOF-MS
Sultan Pekacar a, Burçin ¨Ozüpek a, Esra Küpeli Akkol a,**, Hakk? Tas¸tan b, Halil Ersan c, Didem Deliorman Orhan
doi : 10.1016/j.jep.2023.117122
Volume 319, Part 1, 30 January 2024, 117122
A network pharmacology integrated serum pharmacochemistry strategy for uncovering efficacy of YXC on hepatocellular carcinoma
Ting-ting Zhou a,1, Wen-jian Zhu a,1, Hui Feng a, Yue Ni b, Zi-wen Li a, Dong-dong Sun a,c,d, Liu Li a,c,d, Jia-ni Tan a,c,d, Cheng-tao Yu a,c,d, Wei-xing Shen a,c,d,*, Hai-bo Cheng
doi : 10.1016/j.jep.2023.117125
Volume 319, Part 1, 30 January 2024, 117125
Distribution profiles of phenolic compounds in a cultivar of wampee (Clausena lansium (Lour.) Skeels) fruits and in vitro anti-inflammatory activity
Fanke Zeng , Mianhong Chen , Shengtao Yang , Ruyi Li *, Xuli Lu , Li Zhang , Tinghui Chen , Shaodan Peng , Wei Zhou , Jihua Li
doi : 10.1016/j.jep.2023.117168
Volume 319, Part 1, 30 January 2024, 117168
Corydalis saxicola Bunting total alkaloids improve NAFLD by suppressing de novo lipogenesis through the AMPK-SREBP1 axis
Yating Guo a,1, Qiushuang Sun a,1, Shijiao Wang b, Mengdi Zhang c, Yuanyuan Lei b, Jiejie Wu a, Xinhong Wang b, Wenjun Hu b, Haitao Meng d, Zhiyu Li e, Luzhou Xu f,***, Fang Huang a,**, Zhixia Qiu
doi : 10.1016/j.jep.2023.117162
Volume 319, Part 1, 30 January 2024, 117162
Anti-hypertension effect of Wuwei Jiangya decoction via ACE2/Ang1-7/MAS signaling pathway in SHR based on network degree-distribution analysis
Pengqian Wang a,1, Danli Hao a,1, Xingjiang Xiong
doi : 10.1016/j.jep.2023.117121
Volume 319, Part 1, 30 January 2024, 117121
Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice: Mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation
Pan Xie a,1, Lixia Chen a,1, Juan Wang a, Xuncui Wang a, Shaojie Yang a,b,*, Guoqi Zhu
doi : 10.1016/j.jep.2023.117165
Volume 319, Part 1, 30 January 2024, 117165
Ameliorative effect of Alangium chinense (Lour.) Harms on rheumatoid arthritis by reducing autophagy with targeting regulate JAK3-STAT3 and COX-2 pathways
Ting Xiao a,b,c,*, Xingyan Cheng a,b,c, Yuan Zhi a,b,c, Fangfang Tian a,b,c, Ai Wu a,b,c, Feilong Huang a,b,c, Ling Tao a,b,c, Zhenghong Guo d,**, Xiangchun Shen
doi : 10.1016/j.jep.2023.117133
Volume 319, Part 1, 30 January 2024, 117133
Development and validation of a simple and rapid UPLC-MS/MS method for loganin and its application in pharmacokinetic and tissue distribution studies
Fan Zhang a,b,1, Yu Yan b,1, Kang Ding b, Wen-Wen Lian b, Li Li c, Wen-Ping Wang b, Cong-Yuan Xia b, Hua Yang d, Jun He b,*, Wei-Ku Zhang b,**, Jie-Kun Xu
doi : 10.1016/j.jep.2023.117130
Volume 319, Part 1, 30 January 2024, 117130
Neuroprotective Effect of Zishen Huoxue Decoction treatment on Vascular Dementia by activating PINK1/Parkin mediated Mitophagy in the Hippocampal CA1 Region
Ziting Zhao a, Le Xie b, Jiayi Shi c, Tonghe Liu c, Shiliang Wang b, Jianhua Huang d, Dahua Wu b,*, Xiuli Zhang
doi : 10.1016/j.jep.2023.117172
Volume 319, Part 1, 30 January 2024, 117172
The anticonvulsant effect of saiga horn on febrile seizures by regulating brain serotonin content and inhibiting neuroinflammation
Jinhu Li a,1, Xiang Yao a,1, Yurou Wu a, Chengwei Wang a, Jincheng Yang a, Chunjie Wu
doi : 10.1016/j.jep.2023.117180
Volume 319, Part 1, 30 January 2024, 117180
Acute and 90-day toxicological safety assessment of Shang-Ke-Huang-Shui lotion in New Zealand White rabbits
Fanghao Zheng *, Tingting Zhao, Zhenyang Liu
doi : 10.1016/j.jep.2023.117027
Volume 319, Part 1, 30 January 2024, 117027
Evaluation of the toxicity of the hydroethanolic extract of the stem bark of Virola elongata (Benth.) Warb. in in vitro and in vivo models
Michellen Santos de Carvalho a, Guilherme Vieira Botelho de Almeida b, Karuppusamy Arunachalam c,d, Edson Moleta Colodel e, Camilo Eduardo Barcenas Olaya e, Domingos Tabajara de Oliveira Martins
doi : 10.1016/j.jep.2023.117171
Volume 319, Part 1, 30 January 2024, 117171
Isolation and characterization of bioactive components from hydroalcoholic extract of Cymbopogon jwarancusa (Jones) Schult. to evaluate its hepatoprotective activity
Sajida Sumaiya a, Aisha Siddiqui a,*, Shahid Shah Chaudhary b, Mohd Aslam a, Sayeed Ahmad c, Mairaj Ahmed Ansari
doi : 10.1016/j.jep.2023.117185
Volume 319, Part 1, 30 January 2024, 117185
Efficacy and mechanism study of Baichanting compound, a combination of Acanthopanax senticosus (Rupr. and Maxim.) Harms, Paeonia lactiflora Pall and Uncaria rhynchophylla (Miq.) Miq. ex Havil, on Parkinson's disease based on metagenomics and metabolomics
doi : 10.1016/j.jep.2023.117182
Volume 319, Part 1, 30 January 2024, 117182
Essential oil from Inula japonica Thunb. And its phenolic constituents ameliorate pulmonary injury and fibrosis in bleomycin-treated mice
Fan Wei a,b,1, Yuzhen Yin a,b,1, Jie Li a,1, Yibo Chang a,c, Shuyuan Zhang a, Wenyu Zhao a,*, Xiaochi Ma
doi : 10.1016/j.jep.2023.117169
Volume 319, Part 1, 30 January 2024, 117169
Shen-Ling-Bai-Zhu-San alleviates the imbalance of intestinal homeostasis in dextran sodium sulfate-induced colitis mice by regulating gut microbiota and inhibiting the NLRP3 inflammasome activation
Qianru Gao a, Weiyi Tian b, Huabing Yang a, Haiming Hu a, Junping Zheng a, Xiaowei Yao a, Baifei Hu a,**, Hongtao Liu
doi : 10.1016/j.jep.2023.117136
Volume 319, Part 1, 30 January 2024, 117136
Yuanzhi powder facilitated Aβ clearance in APP/PS1 mice: Target to the drainage of glymphatic system and meningeal lymphatic vessels
Jiaxin Li a, Yanwei Hao a, Shaofeng Wang a, Wei Li b, Shengnan Yue a, Xueqing Duan a, Yuting Yang c, Bin Li
doi : 10.1016/j.jep.2023.117195
Volume 319, Part 1, 30 January 2024, 117195
Qishen granule attenuates doxorubicin-induced cardiotoxicity by protecting mitochondrial function and reducing oxidative stress through regulation of Sirtuin3
Jingmei Zhang a,1, Weili Li b,1, Siming Xue a,1, Pengrong Gao b, Hui Wang a, Huan Chen a, Yiqin Hong a, Qianbin Sun b, Linghui Lu b,c,d,**, Yong Wang b,c,d,***, Qiyan Wang
doi : 10.1016/j.jep.2023.117134
Volume 319, Part 1, 30 January 2024, 117134
Panax notoginseng saponins inhibits oxidative stress- induced human nucleus pulposus cell apoptosis and delays disc degeneration in vivo and in vitro
Danqing Guo a,*, Miao Yu b, Huizhi Guo c, Min Zeng d, Yang Shao e, Wei Deng e, Qiuli Qin e, Yongxian Li c, Shuncong Zhang
doi : 10.1016/j.jep.2023.117166
Volume 319, Part 1, 30 January 2024, 117166
Buddlejasaponin IVb ameliorates ferroptosis of dopaminergic neuron by suppressing IRP2-mediated iron overload in Parkinson's disease
Qiang-Ming Li a,1, Tong Xu a,1, Xue-Qiang Zha a, Xiao-Wen Feng c, Feng-Yun Zhang b,*, Jian-Ping Luo
doi : 10.1016/j.jep.2023.117196
Volume 319, Part 1, 30 January 2024, 117196
Phytochemical composition, toxicological profiling and effect on pup birth weight of Corchorus olitorius leaf extract in rats: Implications for fetal macrosomia control
Onyinye Mkpola Ukpai a, Solomon Nnah Ijioma a, Kingsley Kanu b, Daniel Orieke c, Peace Amarachi Chinedu-Ndukwe a, Kingsley Chijioke Ugwuanyi a, Eziuche Amadike Ugbogu
doi : 10.1016/j.jep.2023.117170
Volume 319, Part 1, 30 January 2024, 117170
Cold pressed Pinus halepensis Mill. seed oil for potential health applications: Analgesic, anti-inflammatory effects, and assessment of inflammatory mediators by RT-qPCR in skin wound healing
Sihem Ait Atmane a,*, Muhammet Burak Bat?r b, Zeynep Aksoylu ¨Ozbek c,d, Pelin Günç Erg¨onül c, Erdal Balcan b, Djedjiga Ait Eldjoudi a, Evrim ¨Ozkale b, Noureddine Bribi a, Bachra Khettal
doi : 10.1016/j.jep.2023.117157
Volume 319, Part 1, 30 January 2024, 117157
Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE−/− mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis
Yan Zhang a,b,1, Dandan Li c,1, Zijun Jia d,a, Jun Mei a,b, Ya Wang a, Ying Zhang a,b,**, Qingbing Zhou a,b,*, Fengqin Xu
doi : 10.1016/j.jep.2023.117188
Volume 319, Part 1, 30 January 2024, 117188
Ruyong formula improves thymus function of CUMS-stimulated breast cancer mice
Bingqian He a,1, Wenqin Guo b,c,1, Rongzhen Shi b,d,1, Robert D. Hoffman e, Qihan Luo b, Yuan-Jia Hu f,**, Jianli Gao
doi : 10.1016/j.jep.2023.117164
Volume 319, Part 1, 30 January 2024, 117164
Exploring the efficacy of various wheat bran extracts in promoting burn wound healing: A comparative analysis
Mai A.M. Ahmed a,*, Marwa F. Ali b, Nesma M. Mohamed a,c, Soad A.L. Bayoumi a, Asmaa M. Zahran d, Khalid I. Elsayh
doi : 10.1016/j.jep.2023.117174
Volume 319, Part 1, 30 January 2024, 117174
An innovative processing driven efficient transformation of rare ginsenosides enhances anti-platelet aggregation potency of notoginseng by integrated analyses of processing-(chemical) profiling-pharmacodynamics
Wenxiang Fan a, Qi Liao a, Linhong Fan a, Qi Li a,b, Longchan Liu a, Ziying Wang a, Yuqi Mei a, Linnan Li a, Li Yang a,**, Zhengtao Wang
doi : 10.1016/j.jep.2023.117126
Volume 319, Part 1, 30 January 2024, 117126
Deciphering the function of Xiangsha-Liujunzi-Tang in enhancing duodenal mucosal barrier by inhibiting MC/Tryptase/PAR-2 signaling pathway in functional dyspepsia rats
Min Bai a,b,1, Linna Zhao a,b,1, Mengya Liu a,1, Runfa Li a, Yuping Yang a, Yugui Zhang a, Xiaomei Yuan a, Yarong Li c, Yongqiang Duan c,**, Yaorong An a, Yingxia Cheng
doi : 10.1016/j.jep.2023.116715
Volume 319, Part 1, 30 January 2024, 116715
In vivo metabolism combined network pharmacology to identify anti-constipation constituents in Aloe barbadensis Mill
doi : 10.1016/j.jep.2023.117200
Volume 319, Part 1, 30 January 2024, 117200
Gleditsiae sinensis fructus Pills combined with Jujubae fructus attenuate chronic bronchitis via regulation of AGE-RAGE signaling pathway
Chang-chang Wang a,1, Le Kang a,b,1, Bei-lei Zuo a, Xin Peng a, Hong-wei Li a,b,c, Ning Zhou a,b,c,**, Kai Li
doi : 10.1016/j.jep.2023.117191
Volume 319, Part 1, 30 January 2024, 117191
The oral administration of Lotus corniculatus L. attenuates acute and chronic pain models in male rats
Sajjad Jabbari a, Zainul Amiruddin Zakaria b, Davoud Ahmadimoghaddam c, Saeed Mohammadi
doi : 10.1016/j.jep.2023.117181
Volume 319, Part 1, 30 January 2024, 117181
Exploring in vitro and in vivo anti-inflammatory activities of the Thai traditional remedy Kheaw-Hom and its bioactive compound, ethyl p-methoxycinnamate, and ethnopharmacological analysis
Kanmanee Sukkasem a, Arunporn Itharat b,c,*, Krittiya Thisayakorn d, Nattapol Tangsuphoom e, Sumalee Panthong b,c, Sunita Makchuchit b,c, Janjira Inprasit b, Nuntika Prommee b, Wicheian Khoenok d, Kanjana Sriyam d, Darunee Pahusee d, Adis Tasanarong f, Buncha Ooraikul g,h, Neal M. Davies
doi : 10.1016/j.jep.2023.117131
Volume 319, Part 1, 30 January 2024, 117131
Research on the mechanism of antidepressive effect of Suanzaoren Decoction through TLR4/MyD88/NF-κB pathway and Wnt/β-catenin pathway
Yiyang Du , Tingxu Yan , Bo Wu , Bosai He **, Ying Jia
doi : 10.1016/j.jep.2023.117190
Volume 319, Part 1, 30 January 2024, 117190
Qufeng Xuanbi Formula inhibited benzo[a]pyrene-induced aggravated asthma airway mucus secretion by AhR/ROS/ERK pathway
Bo-Han Wang a,1, Ling-Ling Tang b,1, Xian-Hong Sun a,1, Qian Zhang c, Chun-Yang Liu d, Xiao-Na Zhang a, Ke-Yao Yu a, Ying Yang a, Jun Hu e, Xiao-Lu Shi a,**, Yue Wang a,***, Li Liu
doi : 10.1016/j.jep.2023.117203
Volume 319, Part 1, 30 January 2024, 117203
Modified Bushen Yiqi formula enhances antitumor immunity by reducing the chemotactic recruitment of M2-TAMs and PMN-MDSCs in Lewis lung cancer-bearing mice
Qing Kong a,b,1, Huahe Zhu a,b,1, Weiyi Gong a,b, Xiaohong Deng a,b, Baojun Liu a,b,*, Jingcheng Dong
doi : 10.1016/j.jep.2023.117183
Volume 319, Part 1, 30 January 2024, 117183
Optimized new Shengmai powder ameliorates myocardial fibrosis in rats with heart failure by inhibition of the MAPK signaling pathway
Zeyu Zhang 1, Yuwei Song 1, Xuan Zhang , Shuai Wang , Zhuangzhuang Jia , Lin Wang , Ci Wang , Xianliang Wang *, Jingyuan Mao
doi : 10.1016/j.jep.2023.117210
Volume 319, Part 1, 30 January 2024, 117210
Shenqu xiaoshi oral solution enhances digestive function and stabilizes the gastrointestinal microbiota of juvenile rats with infantile anorexia
Meng Zhao a,1, Ting Xiang b,1, Zhikui Dong c, Guorui Liu b, Pengran Wang b, Xiaoxu Qi b, Qingqing Hao a, Na Han a, Zhihui Liu a, Sikai Li a, Jun Yin a,*, Jianxiu Zhai
doi : 10.1016/j.jep.2023.117112
Volume 319, Part 1, 30 January 2024, 117112
Characterization of the glucuronidating pathway of pectolinarigenin, the major active constituent of the Chinese medicine Daji, in humans and its influence on biological activities
Peiqi Liu a,b, Qian Li b, Guanghao Zhu b, Tiantian Zhang b, Dongzhu Tu b, Feng Zhang b, Moshe Finel c, Yuqi He a,**, Guangbo Ge
doi : 10.1016/j.jep.2023.117280
Volume 319, Part 1, 30 January 2024, 117280
Network pharmacology integrated with experimental validation revealed the mechanism of Fengshi Gutong Capsule in the treatment of osteoarthritis
Yanqiu Sun a,c, Jian Liu a,c,*, Jue Wang b, Mingyu He a,c, Xiaolu Chen a,c, Li Chen
doi : 10.1016/j.jep.2023.117261
Volume 319, Part 1, 30 January 2024, 117261
Corrigendum to “Application of omics technology to investigate the mechanism underlying the role of San Hua Tang in regulating microglia polarization and blood-brain barrier protection following ischemic stroke� [J. Ethnopharmacol. 314 (2023) 116640]
Shan Luo a,b, Yuanchun Chen a, Ruoxi Zhao a, Donglai Ma c, Yanmeng Zhao d, Ying Zhang d,e, Jianming Jiang c,**, Wentao Yu
doi : 10.1016/j.jep.2023.117155
Volume 319, Part 1, 30 January 2024, 117155
Corrigendum to “Clinical efficacy of Shugan granule in the treatment of mixed anxiety-depressive disorder: A multicenter, randomized, double-blind, placebo-controlled trial� [J. Ethnopharmacol. 290 (2022) 115032]
Yang Li a, Liqi Li b, Rongjuan Guo c,*, Hua Yu d, Xinping Wang d, Baoshen Wang e, Qiufeng Wang e, Zengxiang Li f, Huixin Zhao f, Qile Temu g, Xiaochun Chen g, Yurong Zhang g, Jinlan An h, Xiaojun Cai i, Anhong Li j, Lihong Qi k, Jinlin Shang l, Huiling He m, Dongdong Yang n, Jiaming Lin o, Yuan Zhang b, Ting Zou
doi : 10.1016/j.jep.2023.117370
Volume 319, Part 1, 30 January 2024, 117370
Corrigendum to “The optimal dose of arsenic trioxide induced opposite efficacy in autophagy between K562 cells and their initiating cells to eradicate human myelogenous leukemia� [J. Ethnopharmacol. 196 (2017) 29–38]
Zhenzhen Guo 1, Mingjing Meng 1, Shengnan Geng, Zhenhua Du, Yaqiu Zheng, Jingjing Yao, Zibo Li, Guang Han, Haihong Lin **, Gangjun Du
doi : 10.1016/j.jep.2023.117391
Volume 319, Part 1, 30 January 2024, 117391
Sida cordifolia L. attenuates behavioral hypersensitivity by interfering with KIF17-NR2B signaling in rat model of neuropathic pain
Vineeta Tiwari , Siva Hemalatha
doi : 10.1016/j.jep.2023.117085
Volume 319, Part 1, 30 January 2024, 117085
Traditionally used anti-diabetic plants in Kathua district of Union Territory of Jammu and Kashmir, India
Madhvi Parasher a,b,*, Devendra Kumar Pandey a,**, R.K. Manhas
doi : 10.1016/j.jep.2023.117087
Volume 319, Part 1, 30 January 2024, 117087
Understanding mechanistic aspect of the therapeutic role of herbal agents on neuroplasticity in cerebral ischemic-reperfusion injury
Annu Bangar a, Heena Khan a, Amarjot Kaur a, Kamal Dua b,c, Thakur Gurjeet Singh
doi : 10.1016/j.jep.2023.117153
Volume 319, Part 2, 30 January 2024, 117153
A review on ethnopharmacology, phytochemistry, pharmacology and potential uses of Portulaca oleracea L.
Kun Li a,b,1, Tianshuang Xia a,1, Yiping Jiang a, Nani Wang c, Liyong Lai a, Shengyan Xu a, Xiaoqiang Yue b,**, Hailiang Xin
doi : 10.1016/j.jep.2023.117211
Volume 319, Part 2, 30 January 2024, 117211
Effect of Crocus sativus L. (saffron) and crocin in the treatment of patients with type-2 diabetes mellitus: A systematic review and meta-analysis
Pedro de Padua G. Amatto a, Lucas Chaves b, Giovana Graça Braga a,c, F´abio Carmona b,1, Ana Maria Soares Pereira
doi : 10.1016/j.jep.2023.117255
Volume 319, Part 2, 30 January 2024, 117255
Traditional uses, phytochemistry, pharmacology, and safety concerns of hawthorn (Crataegus genus): A comprehensive review
Meng Cui a, Lei Cheng a, Zhongyu Zhou a,b, Zemei Zhu a, Yinglin Liu a, Chaohai Li a, Binbin Liao a, Min Fan a,*, Baozhong Duan
doi : 10.1016/j.jep.2023.117229
Volume 319, Part 2, 30 January 2024, 117229
Cholinergic signaling of muscarinic receptors directly involves in the neuroprotection of muscone by inducing Ca2+ antagonism and maintaining mitochondrial function
Gang Shen a,b, Zongyuan Zhou c, Yanlei Guo b, Li Li b, Jin Zeng b, Jianbo Wang b,*, Junning Zhao
doi : 10.1016/j.jep.2023.117192
Volume 319, Part 2, 30 January 2024, 117192
Guizhi Fuling Formulation: A review on chemical constituents, quality control, pharmacokinetic studies, pharmacological properties, adverse reactions and clinical applications
Xinyue Liu, Lele Chen, Peng Sun, Zhaoshuang Zhan **, Jiafeng Wang
doi : 10.1016/j.jep.2023.117277
Volume 319, Part 2, 30 January 2024, 117277
The genus Actinidia Lindl. (Actinidiaceae): A comprehensive review on its ethnobotany, phytochemistry, and pharmacological properties
doi : 10.1016/j.jep.2023.117222
Volume 319, Part 2, 30 January 2024, 117222
Review of the therapeutic potential of Forsythiae Fructus on the central nervous system: Active ingredients and mechanisms of action
Leying Zhang a, Fenglong Lang b, Juan Feng a, Jue Wang
doi : 10.1016/j.jep.2023.117275
Volume 319, Part 2, 30 January 2024, 117275
Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
Suman Kumar Samanta a,b,*,1, Paramita Choudhury b,c,1, Raghuram Kandimalla b,d,e,1, Farrukh Aqil d,f, Disha N. Moholkar d,e, Ramesh C. Gupta d,e, Momita Das b, Bhaskarjyoti Gogoi g, Neelutpal Gogoi h, Partha Pratim Sarma b, Rajlakshmi Devi b,**, Narayan C. Talukdar
doi : 10.1016/j.jep.2023.117235
Volume 319, Part 2, 30 January 2024, 117235
Research progress on traditional Chinese medicine-induced apoptosis signaling pathways in ovarian cancer cells
Yu Wang a,1, Liangzhen Xie b, Fangyuan Liu b, Danni Ding a, Wei Wei a, Fengjuan Han
doi : 10.1016/j.jep.2023.117299
Volume 319, Part 2, 30 January 2024, 117299
A comprehensive review of the classical prescription Yiguan Jian: Phytochemistry, quality control, clinical applications, pharmacology, and safety profile
Changcheng Lu a,b,1, Siyuan Zhang a,b,1, Si San Lei a,b, Danni Wang a, Bo Peng a,b, Ruipeng Shi a,b, Cheong-Meng Chong a,**, Zhangfeng Zhong a,b,*, Yitao Wang
doi : 10.1016/j.jep.2023.117230
Volume 319, Part 2, 30 January 2024, 117230
Medicinal patterns of vines used in Chinese herbal medicine: a quantitative study
Yanlin Ding a,b,1, Dingping Zhao a,b,1, Tingye Wang a,b,1, Zhenyu Xu a,b, Yuxuan Fu a,b, Li Tao
doi : 10.1016/j.jep.2023.117184
Volume 319, Part 2, 30 January 2024, 117184
Herbal therapeutics for female infertility: A systematic review and meta-analysis
Ji-Yoon Hyun , Hyeon-Suk Jung , Ji-Yeun Park
doi : 10.1016/j.jep.2023.117258
Volume 319, Part 2, 30 January 2024, 117258
Mechanism of herb pair containing Astragali Radix and Spatholobi Caulis in the treatment of myelosuppression based on network pharmacology and experimental investigation
Fei Peng a,b, Wanying Hong a, Yingyu Wang a,b, Yunru Peng a,b,*, Zhijun Fang
doi : 10.1016/j.jep.2023.117178
Volume 319, Part 2, 30 January 2024, 117178
Cholinergic signaling of muscarinic receptors directly involves in the neuroprotection of muscone by inducing Ca2+ antagonism and maintaining mitochondrial function
Gang Shen a,b, Zongyuan Zhou c, Yanlei Guo b, Li Li b, Jin Zeng b, Jianbo Wang b,*, Junning Zhao
doi : 10.1016/j.jep.2023.117192
Volume 319, Part 2, 30 January 2024, 117192
Guizhi Fuling Formulation: A review on chemical constituents, quality control, pharmacokinetic studies, pharmacological properties, adverse reactions and clinical applications
Xinyue Liu, Lele Chen, Peng Sun, Zhaoshuang Zhan **, Jiafeng Wang
doi : 10.1016/j.jep.2023.117277
Volume 319, Part 2, 30 January 2024, 117277
The genus Actinidia Lindl. (Actinidiaceae): A comprehensive review on its ethnobotany, phytochemistry, and pharmacological properties
doi : 10.1016/j.jep.2023.117222
Volume 319, Part 2, 30 January 2024, 117222
Review of the therapeutic potential of Forsythiae Fructus on the central nervous system: Active ingredients and mechanisms of action
Leying Zhang a, Fenglong Lang b, Juan Feng a, Jue Wang
doi : 10.1016/j.jep.2023.117275
Volume 319, Part 2, 30 January 2024, 117275
Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
Suman Kumar Samanta a,b,*,1, Paramita Choudhury b,c,1, Raghuram Kandimalla b,d,e,1, Farrukh Aqil d,f, Disha N. Moholkar d,e, Ramesh C. Gupta d,e, Momita Das b, Bhaskarjyoti Gogoi g, Neelutpal Gogoi h, Partha Pratim Sarma b, Rajlakshmi Devi b,**, Narayan C. Talukdar
doi : 10.1016/j.jep.2023.117235
Volume 319, Part 2, 30 January 2024, 117235
Research progress on traditional Chinese medicine-induced apoptosis signaling pathways in ovarian cancer cells
Yu Wang a,1, Liangzhen Xie b, Fangyuan Liu b, Danni Ding a, Wei Wei a, Fengjuan Han
doi : 10.1016/j.jep.2023.117299
Volume 319, Part 2, 30 January 2024, 117299
A comprehensive review of the classical prescription Yiguan Jian: Phytochemistry, quality control, clinical applications, pharmacology, and safety profile
Changcheng Lu a,b,1, Siyuan Zhang a,b,1, Si San Lei a,b, Danni Wang a, Bo Peng a,b, Ruipeng Shi a,b, Cheong-Meng Chong a,**, Zhangfeng Zhong a,b,*, Yitao Wang
doi : 10.1016/j.jep.2023.117230
Volume 319, Part 2, 30 January 2024, 117230
Medicinal patterns of vines used in Chinese herbal medicine: a quantitative study
Yanlin Ding a,b,1, Dingping Zhao a,b,1, Tingye Wang a,b,1, Zhenyu Xu a,b, Yuxuan Fu a,b, Li Tao
doi : 10.1016/j.jep.2023.117184
Volume 319, Part 2, 30 January 2024, 117184
Herbal therapeutics for female infertility: A systematic review and meta-analysis
Ji-Yoon Hyun , Hyeon-Suk Jung , Ji-Yeun Park
doi : 10.1016/j.jep.2023.117258
Volume 319, Part 2, 30 January 2024, 117258
Mechanism of herb pair containing Astragali Radix and Spatholobi Caulis in the treatment of myelosuppression based on network pharmacology and experimental investigation
Fei Peng a,b, Wanying Hong a, Yingyu Wang a,b, Yunru Peng a,b,*, Zhijun Fang
doi : 10.1016/j.jep.2023.117178
Volume 319, Part 2, 30 January 2024, 117178
Pyrolae herba alleviates cognitive impairment via hippocampal TREM2 signaling modulating neuroinflammation and neurogenesis in lipopolysaccharide-treated mice
Yan Sun a,b,1, Hailou Zhang c,1, Ruiyu Liu a,b,c, Rumin Huang a,b, Xiangrui Zhang a,b, Shihan Zhou a,b, Lei Wu d, Boran Zhu a,b,**, Haoxin Wu
doi : 10.1016/j.jep.2023.117214
Volume 319, Part 2, 30 January 2024, 117214
Guben Xiezhuo Decoction inhibits M1 polarization through the Raf1/p-Elk1 signaling axis to attenuate renal interstitial fibrosis
Yue Liu a,b,1, Jingyi Wu a,b,1, Shuo Liang a, Jiawei Xu a, Minggang Wei c,***, Zhenfang Du a,**, Sheng Qiang
doi : 10.1016/j.jep.2023.117189
Volume 319, Part 2, 30 January 2024, 117189
SiJunZi decoction ameliorates bone quality and redox homeostasis and regulates advanced glycation end products/receptor for advanced glycation end products and WNT/β-catenin signaling pathways in diabetic mice
Xuan Dai a,1, Yage Liu a,1, Tianyuan Liu a, Yueyi Zhang a, Shan Wang a, Tianshu Xu a, Jiyuan Yin a, Hanfen Shi a, Zimengwei Ye a, Ruyuan Zhu a, Junfeng Gao b, Guangtong Dong c, Dandan Zhao a, Sihua Gao a, Xinxiang Wang b, Marc Prentki d, Dieter Br?mme e, Lili Wang f,**, Dongwei Zhang
doi : 10.1016/j.jep.2023.117167
Volume 319, Part 2, 30 January 2024, 117167
Mechanism difference of ginseng medicines with different natures on hyperthyroidism
Linlin Liu a, Xueying Han a, Guoshun Shan b,**, Li Fu c, Deqiang Dou
doi : 10.1016/j.jep.2023.117194
Volume 319, Part 2, 30 January 2024, 117194
Effect and mechanism of Qing Gan Zi Shen decoction on heart damage induced by obesity and hypertension
Shujie Zhang a,1, Zitian Liu a,1, Han Zhang a,1, Xiaonian Zhou a, Xiuming Wang a, Yan Chen a, Xiaofan Miao a, Yao Zhu a,*, Weimin Jiang
doi : 10.1016/j.jep.2023.117163
Volume 319, Part 2, 30 January 2024, 117163
In vitro and in vivo anti-inflammatory and antiophidic effects of the extract and fraction of Eugenia uniflora
Alessandra Daniele-Silva a,b, Adriana Marina e Silva Parente a,b, Sarah de Sousa Ferreira b, Diana Pontes da Silva b, Manoela Torres-Rˆego b,c, Felipe França Cavalcanti b,c, Magda Rhayanny Assunç?ao Ferreira a, Matheus de Freitas Fernandes-Pedrosa b, Luiz Alberto Lira Soares
doi : 10.1016/j.jep.2023.117223
Volume 319, Part 2, 30 January 2024, 117223
Phytochemical characterization, anti-diarrhoeal, analgesic, anti-inflammatory activities and toxicity profile of Ananas comosus (L.) Merr (pineapple) leaf in albino rats
Eziuche Amadike Ugbogu a,*, Happiness Okoro a, Okezie Emmanuel a, Ositadinma Chinyere Ugbogu b, Celestine Nwabu Ekweogu c, Miracle Uche a, Emmanuel Dike Dike a, Solomon Nnah Ijioma
doi : 10.1016/j.jep.2023.117224
Volume 319, Part 2, 30 January 2024, 117224
Stigmasterol and gastrodin, two major components of banxia-baizhu-tianma decoction, alleviated the excessive phlegm-dampness hypertension by reducing lipid accumulation
Honghua Zhang a,b, Yunting Sun c,**, Yuqing Zou a,b, Cheng Chen a,b, Shuling Wang
doi : 10.1016/j.jep.2023.117193
Volume 319, Part 2, 30 January 2024, 117193
The beneficial effect of Sanhuang ointment and its active constituents on experimental hemorrhoids in rats
Qian Yu a,1, Yu Zhao a,1, Xinyue Zhang a, Wenjie Li a, Hongyin Zhang a,b, Songlan Piao a, Guangzhe Li a,b,c,**, Mingming Yan
doi : 10.1016/j.jep.2023.117173
Volume 319, Part 2, 30 January 2024, 117173
TMT-based quantitative proteomics reveals the protective mechanism of tenuigenin after experimental intracerebral hemorrhage in mice
Peng Wang a,b,1, YiQing Shen a,b,1, Anatol Manaenko a,b, FangYu Liu a,b, WenSong Yang a,b, ZhongSong Xiao a,b, PeiZheng Li a,b, YuXin Ran a,b, RuoZhi Dang a,b, Yong He a,b, QingYuan Wu b,c, Peng Xie a,b,*, Qi Li
doi : 10.1016/j.jep.2023.117213
Volume 319, Part 2, 30 January 2024, 117213
Integrated analysis of metabolomic and transcriptomic profiling reveals the effect of Atractylodes oil on Spleen Yang Deficiency Syndrome in rats
Xin Zhan a,1, Yangxin Xiao a,1, Qipan Jian a, Yan Dong a, Chang Ke a, Zhongshi Zhou a,b, Yanju Liu a,b,**, Jiyuan Tu
doi : 10.1016/j.jep.2023.117205
Volume 319, Part 2, 30 January 2024, 117205
Black mulberry extract inhibits hepatic adipogenesis through AMPK/mTOR signaling pathway in T2DM mice
Yudi Yao a,1, Yang Chen b,1, Huijian Chen a, Xin Pan a, Xiaojun Li a, Wenqi Liu a, Yerlan Bahetjan a, Binan Lu c, Kejian Pang d, Xinzhou Yang a,*, Zongran Pang
doi : 10.1016/j.jep.2023.117216
Volume 319, Part 2, 30 January 2024, 117216
Xuanbai Chengqi Decoction alleviates acute lung injury by inhibiting NLRP3 inflammasome
Shun Wang a,b,1, Feifei Lin c,1, Chengxi Zhang a,b, Dan Gao a,b, Zhuocao Qi a,b, Suwan Wu a,b, Wantao Wang a,b, Xiaoqian Li a,b, Lingyun Pan d, Yanwu Xu e, Bo Tan f,**, Aidong Yang
doi : 10.1016/j.jep.2023.117227
Volume 319, Part 2, 30 January 2024, 117227
Di-Huang-Yin-Zi regulates P53/SLC7A11 signaling pathway to improve the mechanism of post-stroke depression
Zhou Yang a,1, Yongxia Jiang a,1, Yang Xiao b,1, Lihui Qian c, Yongqu Jiang a, Yue Hu b,d,**, Xiaoli Liu
doi : 10.1016/j.jep.2023.117226
Volume 319, Part 2, 30 January 2024, 117226
Fagopyrum tataricum (L.) Gaertn interacts with Gsk-3β/Nrf-2 signalling to protect neurotoxicity in a zebrafish model
Shubham Nilkanth Rahmatkar a,b, Anil Kumar Rana a,b, Rajneesh Kumar a,b, Damanpreet Singh
doi : 10.1016/j.jep.2023.117187
Volume 319, Part 2, 30 January 2024, 117187
Deciphering the antifungal mechanism and functional components of cinnamomum cassia essential oil against Candida albicans through integration of network-based metabolomics and pharmacology, the greedy algorithm, and molecular docking
Keru Gu a,1, Shengyi Feng b,1, Xinyue Zhang a, Yuanyuan Peng a, Peipei Sun a, Wenchi Liu a, Yi Wu a, Yun Yu a, Xijian Liu a, Xiaohui Liu a, Guoying Deng c, Jun Zheng b,***, Bo Li b,**, Linjing Zhao
doi : 10.1016/j.jep.2023.117156
Volume 319, Part 2, 30 January 2024, 117156
Anti-inflammatory, antioxidant and photoprotective activity of standardised Gaultheria procumbens L. leaf, stem, and fruit extracts in UVA-irradiated human dermal fibroblasts
Piotr Michel a,*, Halina Ma?gorzata ?Zbikowska b, Karolina Rudnicka c, Weronika Gonciarz c, Agnieszka Krupa c, Adrian Gajewski d, Paulina Macha?a b, Monika Anna Olszewska
doi : 10.1016/j.jep.2023.117219
Volume 319, Part 2, 30 January 2024, 117219
Intervention effect of Lycium barbarum polysaccharide on lead-induced kidney injury mice and its mechanism: A study based on the PI3K/Akt/mTOR signaling pathway
Wen Xie a,b, Hua-guo Chen a,b, Ru-hai Chen a,b, Chao Zhao a,b, Xiao-jian Gong a,b, Xin Zhou
doi : 10.1016/j.jep.2023.117197
Volume 319, Part 2, 30 January 2024, 117197
Yi-shen-hua-shi granules modulate immune and inflammatory damage via the ALG3/PPARγ/NF-κB pathway in the treatment of immunoglobulin a nephropathy
Rongjia Xu a,b,1, Jiajia Zhang a,b,1, Xingge Hu a,b, Penghao Xu a,b, Shiqi Huang a,b, Shiyan Cui a,b, Yuxin Guo a,b, Hongtao Yang a,b, Xiangmei Chen c, Chen Jiang
doi : 10.1016/j.jep.2023.117204
Volume 319, Part 2, 30 January 2024, 117204
Prunella vulgaris L. attenuates gut dysbiosis and endotoxin leakage against alcoholic liver disease
Pei-Li Rao a,b,1, Yun-Hui Shen a,1, Yi-Jie Song a,b, Yu Xu a,b,**, Hong-Xi Xu
doi : 10.1016/j.jep.2023.117237
Volume 319, Part 2, 30 January 2024, 117237
Quality evaluation of Angelica Sinensis Radix dispensing granules by integrating microvascular activity and chemical analysis
Wen-jie Li a,e,1, Yu-feng Cai a,1, Yi Ouyang b,1, Xian-yu Li a,d, Xiao-lu Shi a,d, Sheng-xuan Cao a, Ying Huang a,d,*,2, Hong-wei Wu b,**,2, Hong-jun Yang
doi : 10.1016/j.jep.2023.117236
Volume 319, Part 2, 30 January 2024, 117236
Chemical characterization, anti-struvite crystal, anti-inflammatory, analgesic, and antidepressant activities of Papaver rhoeas L. root and leaf extracts
Anouar Hmamou a,*, Mostafa El Khomsi b, El-Mehdi El-Assri a,c, Mohammed Kara d, Fatima Ezzahra El oumari e, Faiçal El Ouadrhiri a, Ahmed Bendaoud a, Ibtissame Elmansouri a,c, Noureddine Eloutassi a, Amal Lahkimi
doi : 10.1016/j.jep.2023.117208
Volume 319, Part 2, 30 January 2024, 117208
The anti-hepatocellular carcinoma effect of Aidi injection was related to the synergistic action of cantharidin, formononetin, and isofraxidin through BIRC5, FEN1, and EGFR
Shan Lu a, Jiaqi Huang a, Jingyuan Zhang a, Chao Wu a, Zhihong Huang a, Xiaoyu Tao a, Leiming You b, Antony Stalin c, Meilin Chen a, Jiaqi Li a, Yingying Tan a, Zhishan Wu a, Libo Geng d, Zhiqi Li a,e, Qiqi Fan a,e, Pengyun Liu a, Yifan Lin a, Chongjun Zhao a,e,**, Jiarui Wu
doi : 10.1016/j.jep.2023.117209
Volume 319, Part 2, 30 January 2024, 117209
Bioactive metabolites reveal the therapeutic consistency of epimedii folium from multi-plant sources for the treatment of kidney-yang deficiency
Xinguang Sun a,1, Yingfei Li b,1, Juan Li c,1, Haizhen Liang a,1, Jie Zhang a, Xiaojuan Chen a, Qi Li a, Xu Pang a, Qianzhi Ding a, Juan Song a, Baolin Guo d,**, Baiping Ma
doi : 10.1016/j.jep.2023.117215
Volume 319, Part 2, 30 January 2024, 117215
Calenduloside E ameliorates non-alcoholic fatty liver disease via modulating a pyroptosis-dependent pathway.
Yifei Le 1, Jianan Guo 1, Zhijun Liu , Jing Liu , Ying Liu , Hang Chen , Jiannan Qiu , Cui Wang , Xiaobing Dou **, Dezhao Lu
doi : 10.1016/j.jep.2023.117239
Volume 319, Part 2, 30 January 2024, 117239
Gancao Xiexin Decoction inhibits gastric carcinoma proliferation and migration by regulating the JAK2/STAT3 signalling pathway
Yating Yang b, Ling Yuan d, Fandi Meng a, Doudou Lu c, Mengying Che a, Xin Zhou b, Guoqing Chen d, Na Ning b, Yi Nan
doi : 10.1016/j.jep.2023.117241
Volume 319, Part 2, 30 January 2024, 117241
The regulatory effect of Angelicae Sinensis Radix on neuroendocrine-immune network and sphingolipid metabolism in CUMS-induced model of depression
Wenxia Gong a,b,c,*, Jinlong Chen a, Shaohua Xu a, Yuanji Li d, Yuzhi Zhou a,b,c, Xuemei Qin
doi : 10.1016/j.jep.2023.117217
Volume 319, Part 2, 30 January 2024, 117217
Xinmaikang (XMK) tablets alleviate atherosclerosis by regulating the SREBP2-mediated NLRP3/ASC/Caspase-1 signaling pathway
Chijun Hou a, Xinyue Jiang b, Wenjuan Sheng a, Yuling Zhang b, Qianbei Lin b, Shihan Hong b, Jiale Zhao b, Ting Wang a, Xiaohan Ye
doi : 10.1016/j.jep.2023.117240
Volume 319, Part 2, 30 January 2024, 117240
Ethnopharmacological analysis based on Thai traditional medicine theory and anti-inflammatory activity of Sa-Tri-Lhung-Klod remedy as a post-partum anti-inflammatory drug
Janjira Inprasit a, Arunporn Itharat b,c,*, Srisopa Ruangnoo b, Krittiya Thisayakorn d,**, Kanmanee Sukkasem b, Nuntika Prommee b, Wicheian Khoenok d, Kanjana Sriyam d, Darunee Pahusee d, Neal M. Davies e,
doi : 10.1016/j.jep.2023.117207
Volume 319, Part 2, 30 January 2024, 117207
Multi-target meridians classification based on the topological structure of anti-cancer phytochemicals using deep learning
Sheng Zhang a, Xianwei Zhang a, Jiayin Du b, Wei Wang c,*, Xitian Pi
doi : 10.1016/j.jep.2023.117244
Volume 319, Part 2, 30 January 2024, 117244
Panax Quinquefolium Saponins enhances angiogenesis in rats with diabetes and myocardial infarction
Deng Pan a,b,d,1, Lin Xu c,1, Pengfei Chen a,b, Lina Miao a,b, Yi Tian e, Dazhuo Shi a,b,**, Ming Guo
doi : 10.1016/j.jep.2023.117252
Volume 319, Part 2, 30 January 2024, 117252
Phthalides from the rhizome of Ligusticum chuanxiong Hort. attenuate diabetic nephropathy in mice
Xin-Yu Qi , Guang-Cheng Peng , Qing-Tong Han **, Jing Yan , Lu-Zhou Chen , Tian Wang , Lin-Tao Xu , Ming-Jie Liu , Zhen-Peng Xu , Xiao-Ning Wang , Tao Shen
doi : 10.1016/j.jep.2023.117247
Volume 319, Part 2, 30 January 2024, 117247
The raw and vinegar-processed Curcuma phaeocaulis Val. ameliorate TAA-induced zebrafish liver injury by inhibiting TLR4/MyD88/NF-κB signaling pathway
Tianhui Gao a,c,d,1, Liting Lin a,1, Qingsong Yang a, Zongping Zhu a, Shuyi Wang a, Tian Xie a,c,d,*, Wan Liao
doi : 10.1016/j.jep.2023.117246
Volume 319, Part 2, 30 January 2024, 117246
Dajianzhong decoction ameliorated D-gal-induced cognitive aging by triggering mitophagy in vivo and in vitro
Mi Zou a,b,1, Dan Wang a,b,1, Yuanyuan Chen b,c, Chuan Yang b,c, Shijun Xu b,c,**, Yuan Dai
doi : 10.1016/j.jep.2023.117212
Volume 319, Part 2, 30 January 2024, 117212
Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway
Gan Li a, Yiwei Ren a, Enmeng Li a, Kai Deng a, Chao Qu a,b, Junxiang Zhang a, Li Zhang a, Xingjie Wang a, Jie Lian c, Huayou Zhou a,d, Zijun Wang a, Tianli Shen a, Xuqi Li a,e,*, Zhengdong Jiang
doi : 10.1016/j.jep.2023.117242
Volume 319, Part 2, 30 January 2024, 117242
Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities
Ru Wang a,b, Jia Zeng c, Lu Chen a,b, Lianlian Sun a,b, Yihai Wang a,b, Jingwen Xu a,b,**, Xiangjiu He
doi : 10.1016/j.jep.2023.117265
Volume 319, Part 2, 30 January 2024, 117265
Huang-Qi-Jian-Zhong-Tang accelerates healing of indomethacin-induced gastric ulceration in rats via anti-inflammatory and antioxidant mechanisms
Houpan Song a,b, Meng Xiong a,b, Chang Yu a,b, Baoping Ren a,b, Meiqi Zhong a,b, Shunhua Zhou a,b, Qing Gao a,b, Chen Ou c, Xiaojuan Wang a,b, Jing Lu c, Meiyan Zeng b,*, Xiong Cai d,**, Qinghua Peng
doi : 10.1016/j.jep.2023.117264
Volume 319, Part 2, 30 January 2024, 117264
Characterization of ACE inhibitory activity in Dioscorea alata cv and its implication as a natural antihypertensive extract
Keaton Logan a, Chukwuemeka Nwokocha c, Helen Asemota a,b, Wesley Gray
doi : 10.1016/j.jep.2023.117221
Volume 319, Part 2, 30 January 2024, 117221
Asiaticoside-nitric oxide promoting diabetic wound healing through the miRNA-21-5p/TGF-β1/SMAD7/TIMP3 signaling pathway
Ye Liu a,b, Jiufeng Zhao c, Xingrui Mu a,b, Junyu Deng a,b, Xingqian Wu a,b, Wenjie He a,b, Yiqiu Liu a,b, Rifang Gu d, Felicity Han e, Xuqiang Nie
doi : 10.1016/j.jep.2023.117266
Volume 319, Part 2, 30 January 2024, 117266
Polysaccharide-rich extract of Genipa americana leaves exerts anti-inflammatory effects modulated by platelet mediators
Diego Freitas de Araujo a, Bianca Feitosa Holanda a, Francisco Lucas Faustino do Nascimento a, Alice Brito Martins a,b, Alefe Lopes Macario Silva c, Maria Gonçalves Pereira a,c, Alana de Freitas Pires a,b, Ana Maria Sampaio Assreuy
doi : 10.1016/j.jep.2023.117234
Volume 319, Part 2, 30 January 2024, 117234
Inhibition of pro-inflammatory cytokines by selected southern African medicinal plants in LPS-stimulated RAW 264.7 macrophages
Gugulethu P. Khumalo a,b, Thanh Nguyen c, Ben-Erik Van Wyk d, Yunjiang Feng b,c, Ian E. Cock
doi : 10.1016/j.jep.2023.117268
Volume 319, Part 2, 30 January 2024, 117268
The inhibitory effect of licorice on the hepatotoxicity induced by the metabolic activation of Euodiae Fructus
Kun Ren a, Xuanmeng Zhang a, Ruijie Wang a, Shumeng Ren a,**, Huiming Hua a, Dongmei Wang b, Yingni Pan a, Xiaoqiu Liu
doi : 10.1016/j.jep.2023.117233
Volume 319, Part 2, 30 January 2024, 117233
An inventory and analysis of the medicinal plants of Mozambique
E. Sitoe , B.-E. Van Wyk
doi : 10.1016/j.jep.2023.117137
Volume 319, Part 2, 30 January 2024, 117137
Esculin ameliorates obesity-induced insulin resistance by improving adipose tissue remodeling and activating the IRS1/PI3K/AKT/GLUT4 pathway
Yong-Yu Yang a,b, Jing-Jing Qi c, Si-Yi Jiang d, Ling Ye
doi : 10.1016/j.jep.2023.117251
Volume 319, Part 2, 30 January 2024, 117251
Fuling-Zexie formula attenuates hyperuricemia-induced nephropathy and inhibits JAK2/STAT3 signaling and NLRP3 inflammasome activation in mice
Meixi Lu a,1, Jiyuan Yin a,1, Tianshu Xu a, Xuan Dai a, Tianyuan Liu a, Yueyi Zhang a, Shan Wang a, Yage Liu a, Hanfen Shi a, Yanfei Zhang b, Fangfang Mo a, Vasily Sukhorukov c, Alexander N. Orekhov c, Sihua Gao a, Lili Wang d,**, Dongwei Zhang
doi : 10.1016/j.jep.2023.117262
Volume 319, Part 2, 30 January 2024, 117262
Yunvjian decoction attenuates lipopolysaccharide-induced periodontitis by suppressing NFκB/NLRP3/IL-1β pathway
Qitao Ye a, Bingfeng Lin b, Pingcui Xu b, Fanxuan Zhang a, Nani Wang a,b,*, Dan Shou
doi : 10.1016/j.jep.2023.117279
Volume 319, Part 2, 30 January 2024, 117279
Revealing the improvement of diabetes by Si Wei Jiang Huang Tang San through ERK/HIF1α signaling pathway via network pharmacology
Tianshu Xu a,1, Ping He b,a,1, So namWangdu e,1, Chunyang Xu c, Biyu Hou a, Peng Ma a, Zijing Wang a, Li Zhang a,d, Guanhua Du a, Tse ring e,**, Tengfei Ji a,***, Guifen Qiang
doi : 10.1016/j.jep.2023.117254
Volume 319, Part 2, 30 January 2024, 117254
Rhei Radix et Rhizoma in Xuanbai-Chengqi decoction strengthens the intestinal barrier function and promotes lung barrier repair in preventing severe viral pneumonia induced by influenza A virus
Linfeng Guo a, Weilian Bao a, Shuiyuan Yang a, Yang Liu a, Jiaren Lyu a, Ting Wang b, Yan Lu a, Hong Li c, Haiyan Zhu b,*, Daofeng Chen
doi : 10.1016/j.jep.2023.117231
Volume 319, Part 2, 30 January 2024, 117231
Zanthoxylum armatum DC fruit ethyl acetate extract site induced hepatotoxicity by activating endoplasmic reticulum stress and inhibiting autophagy in BRL-3A models
Jian Zhang a,c, Jiafu Guo a,c, Nannan Yang a,c, Yan Huang b, Jiayu Wen a,c, Qiwen Xiang a,c, Qiuyan Liu a,c, Yan Chen a,c, Tingting Hu a,c,**, Chaolong Rao
doi : 10.1016/j.jep.2023.117245
Volume 319, Part 2, 30 January 2024, 117245
Modified Shoutai Pill inhibited ferroptosis to alleviate recurrent pregnancy loss
Yuling Lai a,b, Yu Zhang a, Huimin Zhang a, Zhenyue Chen a, Lihua Zeng a, Gaopi Deng c, Songping Luo c,**, Jie Gao
doi : 10.1016/j.jep.2023.117028
Volume 319, Part 2, 30 January 2024, 117028
Shuyu decoction exhibits anti-fatigue properties via alleviating exercise-induced immune dysfunction
Shujing Zhang 1, Yuemeng Sun 1, Jiarou Wang 1, Yixing Lu, Huimin Yuan, Yulin Zong, Haoyu Zhu, Yang Tang, Yan Sun **, Fengjie Zheng ***, Yuhang Li
doi : 10.1016/j.jep.2023.117259
Volume 319, Part 2, 30 January 2024, 117259
NLRP3 neuroinflammatory intervention of Mahuang-Lianqiao-Chixiaodou decoction for mental disorders in atopic dermatitis mice
Huimin Yuan 1, Yang Tang 1, Shujing Zhang 1, Shuxin Yan , Aorou Li , Yanru Yu , Yan Sun **, Fengjie Zheng
doi : 10.1016/j.jep.2023.117263
Volume 319, Part 2, 30 January 2024, 117263
Efficacy of Trigonella foenum-graecum Linné in an animal model of particulate matter-induced asthma exacerbation
Eun-Young Kim a,1, Hoyeon Park a,1, Eom Ji Kim a, Seung Hoon Lee a, Jun Won Choi a, Jonghyun Kim b, Hyuk-Sang Jung a,*, Youngjoo Sohn
doi : 10.1016/j.jep.2023.117228
Volume 319, Part 2, 30 January 2024, 117228
Multi-omics analysis of Gwakhyangjeonggi-san for gastrointestinal complications in atopic dermatitis: A randomized, double-blinded, placebo-controlled, parallel-group clinical trial
Mi Mi Ko a,1, Sarah Shin a,1, Min Hee Kim b,**, Minseo Kang b, Min-gyung Baek c, Hana Yi c,d, Mi Ju Son a, Jeeyoun Jung
doi : 10.1016/j.jep.2023.117256
Volume 319, Part 2, 30 January 2024, 117256
Lanhuashen stimulates the positive cross-regulation mediated by the S1P axis to ameliorate the disorder of glucolipid metabolism induced by the high sucrose diet in Drosophila melanogaster
Gengyuan Yu a,1, Mo Sun c,1, Tonghua Zhang a, Haoran Xu a, Jiaqi Wang a, Wanting Ye a, Peng Wang a, Shiyun Zhang a, Chenning Zhang b,**, Yikun Sun
doi : 10.1016/j.jep.2023.117248
Volume 319, Part 2, 30 January 2024, 117248
Therapeutic effects and mechanisms of Inonotus hispidus extract and active monomer compounds in a rat mammary gland hyperplasia model
Chen Han a,b, Haiying Bao
doi : 10.1016/j.jep.2023.117274
Volume 319, Part 2, 30 January 2024, 117274
Effects of caatinga propolis from Mimosa tenuiflora and its constituents (santin, sakuranetin and kaempferide) on human immune cells
Arthur Alves Sartori a,1, Ninh The Son b,c,1, Mariana da Silva Honorio a, Nicolas Ripari a, Karina Basso Santiago a, Anderson Moreira Gomes a, Willian Fernando Zambuzzi a, Jairo Kenupp Bastos c, Jos´e Maur?cio Sforcin
doi : 10.1016/j.jep.2023.117297
Volume 319, Part 2, 30 January 2024, 117297
Interpretation of the anti-influenza active ingredients and potential mechanisms of Ge Gen Decoction based on spectrum-effect relationships and network analysis
Xiyu Liu a,1, Siyuan Ke a,1, Xiuyi Wang a, Yaqun Li b, Jiantao Lyu c,**, Yu Liu d,***, Zikai Geng
doi : 10.1016/j.jep.2023.117290
Volume 319, Part 2, 30 January 2024, 117290
Protective effect of Huangqi-Guizhi-Wuwutang against cyclophosphamide-induced spermatogenesis dysfunction in mice by promoting steroid hormone biosynthesis
Yuan Zhao a,*,1, Jinru Wu a,1, Xiangbin Li b, Qiugu Chen a, Zhiming Hong a, Lin Zheng a, Shiying Huang a, Pingli Mo a, Changhui Li a, Rui Wang a, Qiuyan Guo c, Shangbin Zhang a, Jianping Chen
doi : 10.1016/j.jep.2023.117260
Volume 319, Part 2, 30 January 2024, 117260
Unveiling the potential mechanisms of Amomi fructus against gastric ulcers via integrating network pharmacology and in vivo experiments
Yana Lv a,b 1, Jiaxin Li c,1, Yao Li d, Jing Su a,b, Xuan Ding a,b, Yin Yuan a,b, Shifang Liu a,b, Yan Mou e, Guang Li a,b,*, Lixia Zhang
doi : 10.1016/j.jep.2023.117179
Volume 319, Part 2, 30 January 2024, 117179
Molecular networking unveils anti-SARS-CoV-2 constituents from traditionally used remedies
Andreas Wasilewicz a,b, Denisa Bojkova c, Mehdi A. Beniddir d, Jindrich Cinatl Jr. c, Holger F. Rabenau c, Ulrike Grienke a, Judith M. Rollinger a, Benjamin Kirchweger
doi : 10.1016/j.jep.2023.117206
Volume 319, Part 2, 30 January 2024, 117206
Potential molecular mechanisms underlying the ameliorative effect of Cola nitida (Vent.) Schott & Endl. on insulin resistance in rat skeletal muscles
Ochuko L. Erukainure a, Olajumoke A. Oyebode a, Anil A. Chuturgoon b, Terisha Ghazi b, Aliyu Muhammad c,d, Aimen Aljoundi e, Ghazi Elamin e, Chika I. Chukwuma f, Md. Shahidul Islam
doi : 10.1016/j.jep.2023.117249
Volume 319, Part 2, 30 January 2024, 117249
QFAE-nB alleviates pulmonary fibrosis by inhibiting the STING pathway in mice
Xueping Wei a,f, Junsong Jing a,f, Rongrong Huang a,f, Ting Zhou d, Lianhao Wu a,f, Guoteng Ou a,f, Youping Wu e, Jingjin Hu a,f, Wenwen Zhu d, Yueguo Wu d, Yuanyuan Li d,**, Sheng Zhang c,***, Zhenqiang You
doi : 10.1016/j.jep.2023.117295
Volume 319, Part 2, 30 January 2024, 117295
Annickia affinis (Exell) Versteegh & Sosef methanol stem bark extract, potent fractions and isolated Berberine alkaloid target both blood and liver stages of malaria parasites
Nekpen Erhunse a,b, Surekha Kumari c,d, Anmol c,d, Pooja Singh e, Ehimwenma Sheena Omoregie b, Agam Prasad Singh e, Upendra Sharma c,d, Dinkar Sahal
doi : 10.1016/j.jep.2023.117269
Volume 319, Part 2, 30 January 2024, 117269
Polygonum perfoliatum L. ethanol extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin inflammation
Pinglong Fan a,b, Shuchun Xie b, ZhiQian Zhang b, Quan Yuan b, Jiajiang He b, Jie Zhang b, Xinyue Liu b, Xiaoyi Liu b, Lieqiang Xu
doi : 10.1016/j.jep.2023.117288
Volume 319, Part 2, 30 January 2024, 117288
Erythrina velutina Willd.: A review of its traditional uses, phytochemistry, pharmacology, and toxicology
Tomi Lois Adetunji a,*, Marvellous Amarachi Acho b, Victory Oghenetega Samuel c, Chinemerem Ruth Ohoro d, Mmbulaheni Ramulondi
doi : 10.1016/j.jep.2023.117273
Volume 319, Part 2, 30 January 2024, 117273
The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro
Shanshan Wang a,b,1, Fei Ye a,1, Qingjia Ren c, Shengnan Sun a, Weina Xia a, Zhuwei Wang a, Haolin Guo a, Han Li a, Shujing Zhang a, Scott Lowe e, Meng Chen a, Qinghong Du a,c,*, Weihong Li
doi : 10.1016/j.jep.2023.117283
Volume 319, Part 2, 30 January 2024, 117283
In vitro and in silico anti-malarial activity and cytotoxicity of n-hexyl 1-O-rutinoside (a glycoside) isolated from Annickia polycarpa (DC.) Setten and Maas ex I.M. Turner (Annonaceae)
Emmanuel Kofi Kumatia a,b,*, Felix Kwame Zoiku c, Alex Asase d, Nguyen Huu Tung
doi : 10.1016/j.jep.2023.117287
Volume 319, Part 2, 30 January 2024, 117287
In silico prediction and experimental validation to reveal the protective mechanism of Puerarin against excessive extracellular matrix accumulation through inhibiting ferroptosis in diabetic nephropathy
Biyu Hou a,1, Peng Ma a,1, Xinyu Yang b,1, Xiaoyue Zhao a,c,d, Li Zhang a,e, Yuerong Zhao a, Ping He a, Li Zhang a, Guanhua Du a,**, Guifen Qiang
doi : 10.1016/j.jep.2023.117281
Volume 319, Part 2, 30 January 2024, 117281
A systematical strategy for quality markers screening of different methods processing Platycodonis radix based on phytochemical analysis and the impact on Chronic Obstructive Pulmonary Disease
Tingting Bai a, Jingying Guo a, Yaling Deng b, Yuqing Zheng a, Jie Shang a, Peng Zheng a, Minmin Liu c, Ming Yang a, Jinlian Zhang
doi : 10.1016/j.jep.2023.117311
Volume 319, Part 2, 30 January 2024, 117311
Multi-omics revealed the mechanisms of Codonopsis pilosula aqueous extract in improving UC through blocking abnormal activation of PI3K/Akt signaling pathway
Fang Li a, Yanping Yang a,c, Junli Ge a, Chunxia Wang a, Zhengjun Chen a, Qin Li a,b, Fude Yang
doi : 10.1016/j.jep.2023.117220
Volume 319, Part 2, 30 January 2024, 117220
Huaier suppresses cisplatin resistance in non-small cell lung cancer by inhibiting the JNK/JUN/IL-8 signaling pathway
Haoyi Jin a,*,1, Changhao Liu a,1, Xi Liu b, Huan Wang a, Yi Zhang a, Yu Liu a, Jijia Li a, Zhanwu Yu a, Hong-xu Liu
doi : 10.1016/j.jep.2023.117270
Volume 319, Part 2, 30 January 2024, 117270
Total Glucosides of White Paeony Capsule ameliorates Parkinson's disease-like behavior in MPTP-induced mice model by regulating LRRK2/alpha-synuclein signaling
Hong-Yan Li a, De-Shui Liu b, Li-Bo Li b, Ying-Bo Zhang b, Hai-Ying Dong b, Hua Rong b, Jing-Yan Zhang b, Jun-Ping Wang b, Ming Jin b, Nan Luo b, Xiao-Jie Zhang a
doi : 10.1016/j.jep.2023.117319
Volume 319, Part 2, 30 January 2024, 117319
Study on the anti-mitochondrial apoptosis mechanism of Erigeron breviscapus injection based on UPLC-Q-TOF-MS metabolomics and molecular docking in rats with cerebral ischemia-reperfusion injury
Jingwen Zhang a,b,1, Mengtian Han b,c,1, Shu Wang c,d,1, Ruixia Wu b,c, Qipeng Zhao c, Meihua Chen c, Yongmao Yang c, Jing Zhang a,b, Xianli Meng b,c,e,**, Yi Zhang a,b,***, Zhang Wang
doi : 10.1016/j.jep.2023.117310
Volume 319, Part 2, 30 January 2024, 117310
Determination and mechanism of Xiao-Ai Jie-Du decoction against diffuse large B-cell lymphoma: In silico and In vitro studies
Xin-Zhuo Zhan a,b,1, Tian-Hua Wei c,1, Yu-Qi Yin c, Jian-Qiao Xu c, Hui Yu a, Xiao-Li Chen a, Xiang-Tu Kong a, Shan-Liang Sun c,d,*, Nian-Guang Li c,**, Hai-Wen Ni
doi : 10.1016/j.jep.2023.117271
Volume 319, Part 2, 30 January 2024, 117271
Phenolic profile, acute and subacute oral toxicity of the aqueous extract from Moroccan Mentha longifolia L. aerial part in Swiss Albino mice model
Meryem Tourabi a,*, Asmae EL Ghouizi a,b,1, Ghizlane Nouioura a,1, Khaoula Faiz c, Hind Elfatemi d, Karima El-yagoubi a, Badiaa Lyoussi a, Elhoussine Derwich
doi : 10.1016/j.jep.2023.117293
Volume 319, Part 2, 30 January 2024, 117293
Efficacy of a Mexican folk remedy containing cuachalalate (Amphipterygium adstringens (Schltdl.) Schiede ex Standl) for the treatment of burn wounds infected with Pseudomonas aeruginosa
Mar?a del Rosario Hortencia G´omez-Salgado a, Jos´e ´Angel Beltr´an-G´omez a, Jos´e Luis D?az- Nu?nez a, Jos´e Alberto Rivera-Ch´avez b, Rodolfo Garc?a-Contreras c, ´Angel Yahir Estrada- Velasco c, H´ector Quezada d, Carlos Alberto Serrano Bello e, Israel Castillo-Ju´arez
doi : 10.1016/j.jep.2023.117305
Volume 319, Part 2, 30 January 2024, 117305
Berberine-silybin salt achieves improved anti-nonalcoholic fatty liver disease effect through regulating lipid metabolism
Xiaolei Ma a,1, Xiaoyou Yu a,1, Rui Li b, Jinjin Cui b, Haoyang Yu b, Ling Ren b, Jiandong Jiang a,b,*, Wenxuan Zhang a,**, Lulu Wang
doi : 10.1016/j.jep.2023.117238
Volume 319, Part 2, 30 January 2024, 117238
Herb pairs containing Curcumae Rhizoma (Ezhu): A review of bio-active constituents, compatibility effects and t-copula function analysis
Liting Lin a,1, Xiaomei Zhou c,d,1, Tianhui Gao a, Zongping Zhu a, Ying Qing a, Wan Liao a,b,*, Wei Lin
doi : 10.1016/j.jep.2023.117199
Volume 319, Part 3, 30 January 2024, 117199
Compound Kushen injection combined with transarterial chemoembolization for hepatocellular carcinoma: An evidence map and overview of systematic reviews
Taicheng Lu a,b,1, Bingtan Kong a,b,1, Yue Wang a,b,1, Jingwen Yu c, Yuancan Pan b, Dong Chen b, Haiming Li b, Xing Chen b, Zichun Yuan a,b, Zhengzheng Yang b, Jiahui Zhang b, Tongjing Ding b, Ganlin Zhang b,***, Qingsheng Fan b,**, Xiaomin Wang b,
doi : 10.1016/j.jep.2023.117267
Volume 319, Part 3, 30 January 2024, 117267
Traditional Chinese medicine for neonatal hypoxic-ischemic encephalopathy: A Bayesian network meta-analysis
Chao Zhang a,b, Jiajia Guo a,c, Huaiqing Yin b,*, Chongjuan Yin b, Yurong Peng
doi : 10.1016/j.jep.2023.117317
Volume 319, Part 3, 30 January 2024, 117317
Research on Coix seed as a food and medicinal resource, it's chemical components and their pharmacological activities: A review
Hongju Li a, Lingxia Peng a, Feng Yin a, Jiahao Fang a, Lietao Cai b, Chaojun Zhang b, Zheng Xiang c, Yuyang Zhao d, Shuifeng Zhang e, Huadong Sheng e, Dekai Wang a, Xiaodan Zhang a,*, Zongsuo Liang
doi : 10.1016/j.jep.2023.117309
Volume 319, Part 3, 30 January 2024, 117309
Mechanisms of Traditional Chinese medicine/natural medicine in HR-positive Breast Cancer: A comprehensive Literature Review
Qinghong Yu a,1, Chuchu Xu a, Jiaqing Song a, Ying Jin a, Xiufei Gao
doi : 10.1016/j.jep.2023.117322
Volume 319, Part 3, 30 January 2024, 117322
The ethnopharmacology, phytochemistry and pharmacology of the genus Hericium
Yu-Fen Tan a,b,1, Ji-Song Mo c,d,1, Yi-Kun Wang c,d, Wei Zhang a,b, Yue-Ping Jiang a,b, Kang-Ping Xu c,d, Gui-Shan Tan a,b, Shao Liu a,b, Jing Li a,b,*, Wen-Xuan Wang
doi : 10.1016/j.jep.2023.117353
Volume 319, Part 3, 30 January 2024, 117353
The genus Balanophora J. R. Forst. & G. Forst. – Its use in traditional medicine, phytochemistry, and pharmacology: A review
Elizabeth Syowai Mutinda a,b,c,e, Dong-Juan Zhang a,b,c,e, Felix Wambua Muema a,b,c,e, Elijah Mbandi Mkala a,b,c,e, Emmanuel Nyongesa Waswa a,b,c,e, Wyclif Ochieng Odago a,b,c,e, Clintone Onyango Ochieng a,b,c,e, Moses Kirega Gichua d, John Kamau Muchuku d, Elizabeth Kamande d, Guang-Wan Hu
doi : 10.1016/j.jep.2023.117276
Volume 319, Part 3, 30 January 2024, 117276
Effect and pharmacological mechanism of Salvia miltiorrhiza and its characteristic extracts on diabetic nephropathy
Luqi Cai a,1, Yu Chen b,1, Huizhong Xue a, Yimeng Yang a, Yuqi Wang a, Junhe Xu a, Chunyan Zhu b, Long He c,*, Yonghua Xiao
doi : 10.1016/j.jep.2023.117354
Volume 319, Part 3, 30 January 2024, 117354
Evaluation of the anti-inflammatory and antioxidant properties and isolation and characterization of a new bioactive compound, 3,4,9-trimethyl-7-propyldecanoic acid from Vitex negundo
Sreewardhini Sivapalan a, Sankari Dharmalingam a,*, Veeramuthu Ashokkumar b,e, Vijayalakshmi Venkatesan c, Mangalagowri Angappan
doi : 10.1016/j.jep.2023.117314
Volume 319, Part 3, 30 January 2024, 117314
Nuezhenoside G13 from Osmanthus fragrans fruit ameliorates Concanavalin A–induced autoimmune hepatitis by regulating the NF-κB/MAPK pathway
Ting Gao a,1, Meng Zhang a,1, Minjie Li a, Xiaoli Wang a, Wenhan Yao b, Wenjie Shu b, Weizhuo Tang b,**, Xiaoshu Zhang
doi : 10.1016/j.jep.2023.117257
Volume 319, Part 3, 30 January 2024, 117257
Integrating plasma metabolomics and gut microbiome to reveal the mechanisms of Huangqi Guizhi Wuwu Decoction intervene diabetic peripheral neuropathy
Kaihui Zhang a, Peng Peng a, Jinhao Huang a, Ming Chen b, Fangle Liu c, Chenchen Zhu a, Qifu Lu b,***, Meiqi Wang a,**, Chaozhan Lin
doi : 10.1016/j.jep.2023.117301
Volume 319, Part 3, 30 January 2024, 117301
Comparative metabolome profiling of Paris polyphylla var. yunnanensis cultivars and Paris luquanensis and their biological activity in zebrafish model
Xue Mei Gao a,*,1, Xin Wang b,1, Wei Si Ma b, Yan Yang b, Li Ping Tang a, Bin Yang
doi : 10.1016/j.jep.2023.117272
Volume 319, Part 3, 30 January 2024, 117272
Saikosaponin a activates tet1/dll3/notch1 signalling and promotes hippocampal neurogenesis to improve depression-like behavior in mice
Yue Tong a,1, Ge Zhao a,c,1, Ruonan Shuang a, Hanqing Wang b,**, Nan Zeng a
doi : 10.1016/j.jep.2023.117289
Volume 319, Part 3, 30 January 2024, 117289
Anemarrhena asphodeloides Bunge total saponins ameliorate diabetic cardiomyopathy by modifying the PI3K/AKT/HIF-1α pathway to restore glycolytic metabolism
Luyang Zhong a,b,c,1, Jianhua Li a,b,c,1, Jiamin Yu a,b,c,1, Xia Cao a,b,c, Jieyong Du a,b,c, Lanyuan Liang a,b,c, Mengru Yang a,b,c, Yimin Yue a,b,c, Mantong Zhao a,b,c, Tong Zhou a,b,c, Jiazi Lin a,b,c, Xiao Wang a,b,c, Xuejuan Shen a,b,c, Yanmei Zhong d,**, Yi Wang a,b,c,***, Zunpeng Shu
doi : 10.1016/j.jep.2023.117250
Volume 319, Part 3, 30 January 2024, 117250
Mechanism of Sophorae Flavescentis Radix (Kushen) in treating NSCLC: Insights from miRNA-mRNA network analysis
Jing Li a,b, Yixian Huang a,b, Jiatong Xu a,b, Huali Zuo a,b, Yun Tang a,b, Hsi-Yuan Huang a,b, Jihang Chen a, Yang-Chi-Dung Lin a,b,**, Hsien-Da Huang
doi : 10.1016/j.jep.2023.117232
Volume 319, Part 3, 30 January 2024, 117232
Assessment of cytotoxicity, acute, subacute toxicities and antioxidant activities (in vitro) of Sanghuangporus vaninii crude polysaccharide
Jinze Liu a,1, Jinyue Song a,1, WeiJia Chen a, Li Sun a, Yan Zhao a, Ying Zong a, Zhongmei He a,b,*, Rui Du
doi : 10.1016/j.jep.2023.117284
Volume 319, Part 3, 30 January 2024, 117284
Bioactive compounds from the leaves of Maytenus ilicifolia Mart. ex Reissek: Inhibition of LDL oxidation, glycation, lipid peroxidation, target enzymes, and microbial growth
Vinicius Prado Bittar a,1, Ana Luiza Silva Borges a,1, Allisson Benatti Justino a, Maria Sol Pe?na Carrillo a, Rener Francisco Mateus Duarte a, Nagela Bernadelli Sousa Silva e, Daniela Silva Gonçalves e, Diego Godina Prado b, Iasmin Aparecida Cunha Ara?jo d, M´ario Machado Martins c, Carlos Henrique Gomes Martins e, Françoise Vasconcelos Botelho a, Neide Maria Silva d, Alberto de Oliveira b, Foued Salmen Esp?ndola
doi : 10.1016/j.jep.2023.117315
Volume 319, Part 3, 30 January 2024, 117315
Gastrodin alleviates cisplatin nephrotoxicity by inhibiting ferroptosis via the SIRT1/FOXO3A/GPX4 signaling pathway
Cai-Wei Qiu a,*, Bo Chen b, Hui-Feng Zhu c, Ying-Lan Liang d, Lin-Shen Mao
doi : 10.1016/j.jep.2023.117282
Volume 319, Part 3, 30 January 2024, 117282
Exploration of the main active metabolites from Tinospora crispa (L.) Hook. f. & Thomson stem as insulin sensitizer in L6.C11 skeletal muscle cell by integrating in vitro, metabolomics, and molecular docking
Ummu Mastna Zuhri a, Nancy Dewi Yuliana b, Fadilah Fadilah a,c,*, Linda Erlina c, Erni Hernawati Purwaningsih a,d, Alfi Khatib
doi : 10.1016/j.jep.2023.117296
Volume 319, Part 3, 30 January 2024, 117296
UPLC-Q-Exactive/MS based analysis explore the correlation between components variations and anti-influenza virus effect of four quantified extracts of Chaihu Guizhi decoction
Liangxin Zhao a,1, Shensi Qian a,1, Xu Wang a, Tiantian Si a, Jinke Xu e, Zhengtao Wang f, Qihui Sun a,***, Yong Yang b,c,**, Rong Rong
doi : 10.1016/j.jep.2023.117318
Volume 319, Part 3, 30 January 2024, 117318
Erchen decoction alleviates the progression of NAFLD by inhibiting lipid accumulation and iron overload through Caveolin-1 signaling
Guanghui Deng a,b,c,1, Junjie Li b,1, Manping Huang d,1, Yunjia Li b, Hao Shi b, Chaofeng Wu b, Jiamin Zhao b, Mengchen Qin b, Chang Liu b, Menghan Yang b, Yunqing Wang f, Yuxue Zhang b, Yuxin Liao b, Chuying Zhou b, Jian Yang g, Yunsheng Xu e,**, Bin Liu a,***, Lei Gao
doi : 10.1016/j.jep.2023.117320
Volume 319, Part 3, 30 January 2024, 117320
Buyang Huanwu decoction ameliorates bleomycin-induced pulmonary fibrosis in rats by attenuating the apoptosis of alveolar type II epithelial cells mediated by endoplasmic reticulum stress
Piao Zhou a,b, Xinhui Wu b, Keling Chen b, Jing Du b, Fei Wang
doi : 10.1016/j.jep.2023.117300
Volume 319, Part 3, 30 January 2024, 117300
Exploring the therapeutic potential of Prinsepia utilis Royle seed oil: A comprehensive study on chemical composition, physicochemical properties, anti-inflammatory, and analgesic activities
Kiran Chauhan a, Piyush Bhalla a, H.R. Chitme b, V.K. Varshney
doi : 10.1016/j.jep.2023.117312
Volume 319, Part 3, 30 January 2024, 117312
Integrating network pharmacology and bioinformatics to explore and experimentally verify the regulatory effect of Buyang Huanwu decoction on glycolysis and angiogenesis after cerebral infarction
Fengming Tian a,c,1, Jian Yi a,b,c,1, Yingfei Liu a,c,1, Bowei Chen a,c, Xiaoju Wang a, Yin Ouyang a,c, Jian Liu a, Yan Tang d, Hongping Long a, Baiyan Liu a,b
doi : 10.1016/j.jep.2023.117218
Volume 319, Part 3, 30 January 2024, 117218
Integration of gut microbiome and serum metabolome revealed the effect of Qing-Wei-Zhi-Tong Micro-pills on gastric ulcer in rats
Chao Wang a, Shengyu Jiang a,b, Haoyu Zheng a, Yiming An a, Wenxue Zheng a, Jiaqi Zhang a, Jianming Liu a,c, Hongqiang Lin a,e, Guoqiang Wang a,e, Fang Wang
doi : 10.1016/j.jep.2023.117294
Volume 319, Part 3, 30 January 2024, 117294
Flavonoid extract from propolis alleviates periodontitis by boosting periodontium regeneration and inflammation resolution via regulating TLR4/MyD88/NF-κB and RANK/NF-κB pathway
Maomao Tang a, Guichun Wang a, Jiaxin Li a, Yuxiao Wang a, Chengjun Peng a, Xiangwei Chang a,b,c,d, Jian Guo a,b,c,d,**, Shuangying Gui
doi : 10.1016/j.jep.2023.117324
Volume 319, Part 3, 30 January 2024, 117324
Bushen Tianjing Recipe inhibits human ovarian granulosa cell line KGN apoptosis induced by miR-23a through the regulation of the sirtuin family
Yanting Wang a,c,1, Guoqiang Liang b, Wei Mu d, Shu Sun d, Xuanyi Chen c,1, Xiaofeng Xu
doi : 10.1016/j.jep.2023.117201
Volume 319, Part 3, 30 January 2024, 117201
Active components and mechanisms of total flavonoids from Rhizoma Drynariae in enhancing cranial bone regeneration: An investigation employing serum pharmacochemistry and network pharmacology approaches
Yuxiao Zhao a,1, Xiaofang Cai b,1, Jian Sun a, Wei Bi a, Youcheng Yu
doi : 10.1016/j.jep.2023.117253
Volume 319, Part 3, 30 January 2024, 117253
DIA-based serum proteomics revealed the protective effect of modified siwu decoction against hypobaric hypoxia
Bodan Tu a,b,1, Yihao Wang b,1,**, Zhenhui Wu a,b, Wei Zhou b, Xianglin Tang b, Cheng Zhang b,c, Yue Gao
doi : 10.1016/j.jep.2023.117303
Volume 319, Part 3, 30 January 2024, 117303
Effect of Echinacea purpurea (L.) Moench and its extracts on the immunization outcome of avian influenza vaccine in broilers
Xinyue Wang a,1, Jiaxin Chen a,b,1, Yanzi Chan a, Sihan Li a, Menglin Li a, Fei Lin a, Khalid Mehmood c, Asif Idrees d, Renzhao Lin a, Yalin Su a, Chunkai Wang a, Dayou Shi
doi : 10.1016/j.jep.2023.117306
Volume 319, Part 3, 30 January 2024, 117306
Integration of single-nucleus RNA sequencing and network disturbance to elucidate crosstalk between multicomponent drugs and trigeminal ganglia cells in migraine
Bo Zhang a, Yujie Xi a,b, Ying Huang b, Yi Zhang a, Feifei Guo a,*, Hongjun Yang a,b
doi : 10.1016/j.jep.2023.117286
Volume 319, Part 3, 30 January 2024, 117286
A comprehensive quality evaluation for Huangqi Guizhi Wuwu decoction by integrating UPLC-DAD/MS chemical profile and pharmacodynamics combined with chemometric analysis
Maoyuan Jiang a,1, Lele Yang a,1, Liang Zou b, Lei Zhang c, Shengpeng Wang a, Zhangfeng Zhong a, Yitao Wang a, Peng Li
doi : 10.1016/j.jep.2023.117325
Volume 319, Part 3, 30 January 2024, 117325
Down-regulation of human papillomavirus E6 oncogene and antiproliferative effect of Schisandra chinensis and Pueraria lobata natural extracts on Hela cell line
Andr´es Cardona-Mendoza a, Angela Fonseca-Benitez a, Diana Marcela Buitrago a,b, Ericsson Coy-Barrera c, Sandra J. Perdomo
doi : 10.1016/j.jep.2023.117225
Volume 319, Part 3, 30 January 2024, 117225
Modulation of mammary tumour progression using murine model by ethanol root extract of Saussurea costus (falc.) lipsch
Rakesh Kumar a,*, Pallavi Bhardwaj b, Mridul Soni a, Rahul Singh a, Sahil Choudhary a, Nitin Virmani c, R.K. Asrani a, Vikram Patial d, Dixit Sharma e, V.K. Gupta a, B.N. Tripathi
doi : 10.1016/j.jep.2023.117302
Volume 319, Part 3, 30 January 2024, 117302
Huayuwendan decoction ameliorates inflammation via IL-17/NF-κB signaling pathway in diabetic rats
Hongyang Wang b,c,1, Fuzhen Pan c,1, Jie Liu c, Juncheng Zhang c, Fuli zhang c, Yu Wang
doi : 10.1016/j.jep.2023.117328
Volume 319, Part 3, 30 January 2024, 117328
Kuijie decoction ameliorates ulcerative colitis by affecting intestinal barrier functions, gut microbiota, metabolic pathways and Treg/Th17 balance in mice
Kaixin Peng 1, Suhong Xia 1, Siqi Xiao, Mingyu Zhang, Jiazhi Liao **, Qin Yu
doi : 10.1016/j.jep.2023.117316
Volume 319, Part 3, 30 January 2024, 117316
TMT-based proteomics analysis identifies the interventional mechanisms of Qijia Rougan decoction in improving hepatic fibrosis
Xiaofeng Chen a,1, Xin Sun a,b,1, Shaoxiu Ji c, Han Yu a,*, Peijie Wu a
doi : 10.1016/j.jep.2023.117334
Volume 319, Part 3, 30 January 2024, 117334
Neurotoxicity study of ethyl acetate extract of Zanthoxylum armatum DC. on SH-SY5Y based on ROS mediated mitochondrial apoptosis pathway
Jiafu Guo a, Nannan Yang a, Jian Zhang a, Yan Huang b, Qiwen Xiang a, Jiayu Wen a, Yan Chen a,b, Tingting Hu a, Liu Qiuyan a,*, Chaolong Rao
doi : 10.1016/j.jep.2023.117321
Volume 319, Part 3, 30 January 2024, 117321
Qi-Zhi-Wei-Tong granules alleviates chronic non-atrophic gastritis in mice by altering the gut microbiota and bile acid metabolism
Man Chen a,1, Ying Li a,1, Lan Li a, Qingyu Ma b, Xuan Zhou b, Fengmin Ding a, Xiaowei Mo b, Wenjun Zhu b, Qinglai Bian a, Xiaojuan Zou a, Feifei Xue b, Li Yan b,***, Xiaojuan Li b,**, Jiaxu Chen
doi : 10.1016/j.jep.2023.117304
Volume 319, Part 3, 30 January 2024, 117304
Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation
He Shuangshuang a,1, Shen Mengmeng b,1, Zhang Lan a, Zhang Fang a, Li Yu
doi : 10.1016/j.jep.2023.117308
Volume 319, Part 3, 30 January 2024, 117308
Understanding apoptotic induction by Sargentodoxa cuneata-Patrinia villosa herb pair via PI3K/AKT/mTOR signalling in colorectal cancer cells using network pharmacology and cellular studies
Bai-Xiang Mu a,1, Yuanxiang Li a,1, Ningyuan Ye a,1, Shenlin Liu b, Xi Zou b, Jun Qian b, Cunen Wu b,c, Yuwen Zhuang b, Min Chen b,**, Jin-Yong Zhou
doi : 10.1016/j.jep.2023.117342
Volume 319, Part 3, 30 January 2024, 117342
Unraveling the mechanism of Yiqi Jiedu formula against nasopharyngeal carcinoma: An investigation integrating network pharmacology, serum pharmacochemistry, and metabolomics
Fangliang Zhou a,b, Wen Wang a, Runshi Xu a, Liu Liu a, Ting Lin a,c, Lan He b,d, Le Tang a,b, Xianwen Wang b,d,**, Yingchun He
doi : 10.1016/j.jep.2023.117343
Volume 319, Part 3, 30 January 2024, 117343
In vitro anti-severe acute respiratory syndrome coronavirus 2 effect of Ephedra przewalskii Stapf extract
Masaki Kakimoto a,b,*, Toshihito Nomura c,d, Tanuza Nazmul d, Akima Yamamoto d, Hiroaki Sasaki d,e, Akifumi Higashiura d, Masanori Ito b, Hiroki Ohge c, Masayuki Mikage f, Keiko Ochiai Ogawa b,g, Takemasa Sakaguchi
doi : 10.1016/j.jep.2023.117341
Volume 319, Part 3, 30 January 2024, 117341
Integrated network pharmacology and metabolomics to investigate the effects and possible mechanisms of Dehydroevodiamine against ethanol-induced gastric ulcers
Xin Wang a, Lei Chang b, Lisheng Chen a, Yong He a, Tingting He c, Ruilin Wang c, Shizhang Wei c, Manyi Jing c, Xuelin Zhou d, Haotian Li c,*, Yanling Zhao a
doi : 10.1016/j.jep.2023.117340
Volume 319, Part 3, 30 January 2024, 117340
Total flavonoids of Litchi chinensis Sonn. seed inhibit prostate cancer growth in bone by regulating the bone microenvironment via inactivation of the HGFR/NF-κB signaling pathway
doi : 10.1016/j.jep.2023.117327
Volume 319, Part 3, 30 January 2024, 117327
Essential oil from Ligusticum chuanxiong Hort. Alleviates lipopolysaccharide-induced neuroinflammation: Integrating network pharmacology and molecular mechanism evaluation
doi : 10.1016/j.jep.2023.117337
Volume 319, Part 3, 30 January 2024, 117337
Phytochemical characterization, in vivo and in vitro biological activities of Atriplex lindleyi Moq. subsp. inflata
Hassina Meguellati a, Saida Ouafi a, Somia Saad a,b, Lylia Harchaoui a, Nadjette Djemouai
doi : 10.1016/j.jep.2023.117333
Volume 319, Part 3, 30 January 2024, 117333
Effects of aqueous extracts and volatile oils prepared from Huaxiang Anshen decoction on p-chlorophenylalanine-induced insomnia mice
Xinye Li a, Chao He a, Min Shen a, Mingyun Wang a, Jingwen Zhou a, Dongying Chen b,**, Tong Zhang a,***, Yiqiong Pu
doi : 10.1016/j.jep.2023.117331
Volume 319, Part 3, 30 January 2024, 117331
Study on the action mechanism of the Polygonum perfoliatum L. on non-alcoholic fatty liver disease, based on network pharmacology and experimental validation
Guanjie Liu a,1, Liu Yang a,1, Yifei Tang c,1, Jiacheng Lin a, Fang Wang a, Jie Shen d,***, Bin Chang b,**, Xiaoni Kong
doi : 10.1016/j.jep.2023.117330
Volume 319, Part 3, 30 January 2024, 117330
Aridanin and oleanane-3- O-β-D-glucoside-2′-acetamide obtained from Tetrapleura tetraptera (Schumach. & Thonn) Taub. (Fabaceae) induces potent apoptotic activity in human prostate cancer cells
Michael Hermann Kengne Kamdem a,b, St´ephane Zingue a,c,d,*, Timothy Grein e, Sebastian Maxeiner e, Jochen Rutz e, Edwin Mpho Mmutlane a,b, Dieudonn´e Njamen f, Roman A. Blaheta e,1, Derek Tantoh Ndinteh a,b,**
doi : 10.1016/j.jep.2023.117298
Volume 319, Part 3, 30 January 2024, 117298
Salvianolic acid B and tanshinone IIA synergistically improve early diabetic nephropathy through regulating PI3K/Akt/NF-κB signaling pathway
Zhuo Xu a, Ke Cai a, Shu-Lan Su a,*, Yue Zhu a, Feng Liu b, Jin-Ao Duan a,
doi : 10.1016/j.jep.2023.117356
Volume 319, Part 3, 30 January 2024, 117356
Explorating the mechanism of Epimedii folium-Rhizoma drynariae herbal pair promoted bone defects healing through network pharmacology and experimental studies
Shan Shan Lei a, Xiao Wen Huang a, Lin Zi Li b, Xu Ping Wang a, Yang Zhang e, Bo Li c,*, Dan Shou
doi : 10.1016/j.jep.2023.117329
Volume 319, Part 3, 30 January 2024, 117329
A composition of ursolic acid derivatives from Ludwigia hyssopifolia induces apoptosis in throat cancer cells via the Akt/mTOR and mitochondrial signaling pathways and by modulating endoplasmic reticulum stress
Wenqi Liu a, Shiwen Kang a, Huijian Chen a, Yerlan Bahetjan a, Jinyan Zhang b, Rumei Lu b, Ni Zheng a, Guangzhong Yang a,**, Xinzhou Yang a
doi : 10.1016/j.jep.2023.117351
Volume 319, Part 3, 30 January 2024, 117351
Xingbei antitussive granules ameliorate cough hypersensitivity in post-infectious cough guinea pigs by regulating tryptase/PAR2/TRPV1 pathway
Yun Li a,d, Ruiheng Zhao a,d, Mengyuan Zhang b,d, Kunlu Shen b,d, Xin Hou c,d, Bowen Liu a,d, Chunxiao Li c,d, Bingqing Sun b,d, Min Xiang a,d, Jiangtao Lin
doi : 10.1016/j.jep.2023.117243
Volume 319, Part 3, 30 January 2024, 117243
Screening the components in multi-biological samples and the comparative pharmacokinetic study in healthy and depression model rats of Suan-Zao-Ren decoction combined with a network pharmacology
Yiyang Du a,1, Jiahong Wang b,1, Li Jiang c, Jinyan Li c, Jiahe Li c, Chuang Ren c, Tingxu Yan a, Ying Jia a, Bosai He
doi : 10.1016/j.jep.2023.117360
Volume 319, Part 3, 30 January 2024, 117360
Mechanism of cryptotanshinone to improve endocrine and metabolic functions in the endometrium of PCOS rats
Yi-Chao Liu a,e,1, Jun-Wen Wang c,1, Jia Li d,1, Ying Guo d, Feng-Juan Han d,**, Wei-Hong Lu c,***, Qiong Wu
doi : 10.1016/j.jep.2023.117346
Volume 319, Part 3, 30 January 2024, 117346
A network pharmacology approach and experimental validation to investigate the anticancer mechanism of Qi-Qin-Hu-Chang formula against colitis-associated colorectal cancer through induction of apoptosis via JNK/p38 MAPK signaling pathway
Yuguang Wu a,b, Yulai Fang a, Yanan Li a,b, Ryan Au a,b,d, Cheng Cheng c, Weiyang Li a,b, Feng Xu a,b, Yuan Cui a,b, Lei Zhu a,**, Hong Shen a
doi : 10.1016/j.jep.2023.117323
Volume 319, Part 3, 30 January 2024, 117323
Bletilla striata polysaccharides protect against ARDS by modulating the NLRP3/caspase1/GSDMD and HMGB1/TLR4 signaling pathways to improve pulmonary alveolar macrophage pyroptosis
Qian Wu a,1, Mingyuan Zhou a,1, Yuchi Chen a, Bingqi Zhu a, Fangmei Zhou a, Xiaoqing Ye a, Yanfen Huang b, Zhishan Ding
doi : 10.1016/j.jep.2023.117361
Volume 319, Part 3, 30 January 2024, 117361
YuPingFeng (YPF) upregulates caveolin-1 (CAV1) to alleviate pulmonary fibrosis through the TGF-β1/Smad2 pathway
Xiao Chen a,b, Min Wei b,1, Guo-Dong Li b,1, Qi-Liang Sun b,1, Jia-Qi Fan c, Jun-Yi Li d, Chun-Mei Yun b, Dao-Ming Liu b, Hong Shi b, Yi-Qing Qu
doi : 10.1016/j.jep.2023.117357
Volume 319, Part 3, 30 January 2024, 117357
Targeting Keap1 with Inulae Herba activated the Nrf2 receptor to alleviate LPS-mediated acute lung injury
Juan Zhang a,b,d,1, Jing Liu a,b,1, Jing-Wen Liu a,b,1, Qi-Meng Zhu a,b, Min Zhang a,b, Rui Zhang c, Xiao-Chi Ma a,**, Xia Lv b, Zhen-Long Yu b, Cheng-Peng Sun
doi : 10.1016/j.jep.2023.117358
Volume 319, Part 3, 30 January 2024, 117358
Ulmus macrocarpa Hance trunk bark extracts inhibit RANKL-induced osteoclast differentiation and prevent ovariectomy-induced osteoporosis in mice
Chanhyeok Jeong a,1, Chang Hyung Lee b,1, Yongjin Lee c,1, Jiwon Seo a, Weihong Wang d,e, Kyu-Hyung Park d, Eunseok Oh d,e, Youbin Cho d, Chanyoon Park b,d, Young-Jin Son c, Jung Han Yoon Park b, Heonjoong Kang b,d,e,f, Ki Won Lee
doi : 10.1016/j.jep.2023.117285
Volume 319, Part 3, 30 January 2024, 117285
In vitro and in vivo antibacterial studies of volatile oil from Atractylodis Rhizoma against Staphylococcus pseudintermedius and multidrug resistant Staphylococcus pseudintermedius strains from canine pyoderma
Tong Xie a,b,1, Jing Lin a,c,1, Degui Lin a, Di Zhang a, Xudong Xu d, Nailiang Zhu e,**, Jiahao Lin a,b,
doi : 10.1016/j.jep.2023.117326
Volume 319, Part 3, 30 January 2024, 117326
Wu-zhu-yu Decoction reduces early brain injury following subarachnoid hemorrhage in vivo and in vitro by activating the Nrf2 antioxidant system via SIRT6 targeting
Min Xu a,1, Qiyu Yue b,c,1, Ziyang He a, Xiaoyang Ling a, Wenhua Wang a, Mingjie Gong
doi : 10.1016/j.jep.2023.117335
Volume 319, Part 3, 30 January 2024, 117335
Stool-softening effect and action mechanism of free anthraquinones extracted from Rheum palmatum L. on water deficit-induced constipation in rats
Huijuan Lv a, Jingjing Niu a, Wenhao Pan a, Yudong Wang a, Lifang Wang a, Meng Wang a, Yali Shi a, Guifang Zhang a, Bandar Al Hamyari a, Shaohua Wang a,b, Xuefeng Li c,**, Yanbin Shi
doi : 10.1016/j.jep.2023.117336
Volume 319, Part 3, 30 January 2024, 117336
Sheng Mai Yin shows anti-fatigue, anti-hypoxia and cardioprotective potential in an experimental joint model of fatigue and acute myocardial infarction
Hao Guo a,1, Pengqi Li b,c,1, Jun Zhao d,1, Qiqi Xin b,c, Yu Miao b,c, Li Li e, Xin Li e, Shanglong Wang e, Hui Mo f, Li Zeng g, Zhenyu Ju h, Zimin Liu e,*, Xiaoxu Shen i,**, Weihong Cong
doi : 10.1016/j.jep.2023.117338
Volume 319, Part 3, 30 January 2024, 117338
Sheng Mai Yin shows anti-fatigue, anti-hypoxia and cardioprotective potential in an experimental joint model of fatigue and acute myocardial infarction
Hao Guo a,1, Pengqi Li b,c,1, Jun Zhao d,1, Qiqi Xin b,c, Yu Miao b,c, Li Li e, Xin Li e, Shanglong Wang e, Hui Mo f, Li Zeng g, Zhenyu Ju h, Zimin Liu e,*, Xiaoxu Shen i,**, Weihong Cong
doi : 10.1016/j.jep.2023.117338
Volume 319, Part 3, 30 January 2024, 117338
Zhi-Zi-Hou-Po decoction alleviates depressive-like behavior and promotes hippocampal neurogenesis in chronic unpredictable mild stress induced mice via activating the BDNF/TrkB/CREB pathway
Zhaoyi Ye a,1, Jinwen Wang a,1, Fei Fang a, Yaya Wang a, Zhebin Liu a, Chunfeng Shen b, Yue Hu
doi : 10.1016/j.jep.2023.117355
Volume 319, Part 3, 30 January 2024, 117355
Ethyl acetate fraction of Osmanthus fragrans var. aurantiacus and its triterpenoids suppress proliferation and survival of colorectal cancer cells by inhibiting NF-κB and COX2
Sanghee Han a,1, Sung-Lyul Lim a,1, Hail Kim a, Hyunjin Choi a, Min Young Lee a, Sun-Yup Shim b, Duc Dat Le c, In Jin Ha a, Mina Lee c,**, Seok-Geun Lee
doi : 10.1016/j.jep.2023.117362
Volume 319, Part 3, 30 January 2024, 117362
The water-soluble subfraction from Artemisia argyi alleviates LPS-induced inflammatory responses via multiple pathways and targets in vitro and in vivo
Le Chen a,b,1, Yunyun Zhu a,1, Yuqiao Wang a,d,1, Zhouyuan Li a,d, Ziling Wang a, Yuhuan Miao a,d, Hongzhi Du a,c,d,*, Dahui Liu
doi : 10.1016/j.jep.2023.117364
Volume 319, Part 3, 30 January 2024, 117364
Fufangxiaopi formula alleviates DSS-induced colitis in mice by inhibiting inflammatory reaction, protecting intestinal barrier and regulating intestinal microecology
Kunjian Liu a, Chong Shi b, Chengqiu Yan b, Yu Yin a, Li Qiu a, Shuangyan He a, Weijie Chen c, Guofeng Li
doi : 10.1016/j.jep.2023.117365
Volume 319, Part 3, 30 January 2024, 117365
E. globulus leaf EO exhibits anti-inflammatory effects by regulating GSDMD-mediated pyroptosis, thereby alleviating neurological impairment and neuroinflammation in experimental stroke mice
doi : 10.1016/j.jep.2023.117367
Volume 319, Part 3, 30 January 2024, 117367
A study integrated metabolomics and network pharmacology to investigate the effects of Shicao in alleviating acute liver injury
Chao Wang a, Rui-Jia Fu a,*, Ding-Qiao Xu a, Qian Zuo a, Ji-Ping Liu b, Yu-Ping Tang
doi : /10.1016/j.jep.2023.117369
Volume 319, Part 3, 30 January 2024, 117369
Anti-inflammatory and urease inhibitory iridoid glycosides from Nyctanthes arbor-tristis Linn.
Talea Sana a, Majid Khan a, Bina S. Siddiqui a,b,*, Tariq Ahmad Baig c, Almas Jabeen c, Sabira Begum a, Taibi B. Hadda d, Luqman Shah
doi : 10.1016/j.jep.2023.117368
Volume 319, Part 3, 30 January 2024, 117378
Croton tiglium L. seeds ameliorate loperamide-induced constipation via regulating gastrointestinal hormones and gut microbiota before and after processing
Ze-Fei Jia , Jia-Li Wang , Wen Pan , Jing Hu
doi : 10.1016/j.jep.2023.117378
Volume 319, Part 3, 30 January 2024, 117378
The compatibility rationality of Sijunzi decoction based on integrated analysis of tissue distribution and excretion characteristics in spleen deficiency syndrome rats
Bangjian Dong , Ying Peng , Mengyue Wang, Chongsheng Peng, Xiaobo Li
doi : 10.1016/j.jep.2023.117376
Volume 319, Part 3, 30 January 2024, 117376
Integrating serum pharmacochemistry and network pharmacology to explore the molecular mechanisms of Acanthopanax senticosus (Rupr. & Maxim.) Harms on attenuating doxorubicin-induced myocardial injury
Xiaoxu Zhang a, Qi Zhang a, Menghan Yu a, Yanfei Zhang a,c, Tianzhu He b, Zhidong Qiu a, Ye Qiu a,**, Weinan Wang
doi : 10.1016/j.jep.2023.117349
Volume 319, Part 3, 30 January 2024, 117349
Green rooibos (Aspalathus linearis) promotes gut health: insight into mechanisms
Lesha Pretorius, Carine Smith
doi : 10.1016/j.jep.2023.117379
Volume 319, Part 3, 30 January 2024, 117379
Investigation of the principle of concoction by using the processing excipient Glycyrrhiza uralensis Fisch. juice to reduce the main toxicity of Dioscorea bulbifera L. and enhance its main efficacy as expectorant and cough suppressant
doi : 10.1016/j.jep.2023.117372
Volume 319, Part 3, 30 January 2024, 117372
Mechanism of DaiTongXiao in the treatment of gouty arthritis through the NLRP3 signaling pathway
Feifan Liu a,1, Fanyi Shen a,1, Yuanmei Bai a,1, Yan Wan a, Lijie Zheng a, Jinglin He a,***, Yuhuan Xie a,**, Peixin Guo
doi : 10.1016/j.jep.2023.117313
Volume 319, Part 3, 30 January 2024, 117313
Network pharmacology-based analysis of Jin-Si-Wei on the treatment of Alzheimer's disease
Jiayi Zhi a,1, Li Yin a,1, Zhoudong Zhang b,1, Yaozhong Lv c,1, Fan Wu a, Yang Yang a, Enming Zhang a, Huanqiu Li b,**, Ning Lu c,***, Mengze Zhou a,*, Qinghua Hu
doi : 10.1016/j.jep.2023.117291
Volume 319, Part 3, 30 January 2024, 117291
Anti-inflammatory potential of a Thai traditional remedy called Prabchompoothaweep in an animal model of acute and sub-acute inflammation
Nittaya Chansiw a,*, Pattranuch Chusri a, Siwaporn Praman a, Thaneeya Hawiset a, Wannisa Sukhorum a, Sorraya Champakam b,c, Rawiwan Charoensup
doi : 10.1016/j.jep.2023.117380
Volume 319, Part 3, 30 January 2024, 117380
The traditional herb Sargentodoxa cuneata alleviates DSS-induced colitis by attenuating epithelial barrier damage via blocking necroptotic signaling
Yuanyuan Wang a,b,c, Bo Zhang c, Siqi Liu a,b, Erping Xu a,b,*, Zhibin Wang
doi : 10.1016/j.jep.2023.117373
Volume 319, Part 3, 30 January 2024, 117373
Effect of woohwangchungsimwon and donepezil co-treatment on cognitive function and serum metabolic profiles in a scopolamine-induced model of Alzheimer's disease
Jung-Seop Kim a,1, Man-Gi Kim b,1, Ji Eun Ryu a, Ye-Been Lee a, Quan Feng Liu b, Kwang Ki Kim c, Seung-Hun Cho d, Sung Joon Shin e, Byung-Soo Koo b,**, Hyung-Kyoon Choi
doi : 10.1016/j.jep.2023.117359
Volume 319, Part 3, 30 January 2024, 117359
Jianpi Huayu Decoction suppresses cellular senescence in colorectal cancer via p53-p21-Rb pathway: Network pharmacology and in vivo validation
Shiting Wang a,1, Ying Xing a,1, Ruiping Wang b, Zhichao Jin
doi : 10.1016/j.jep.2023.117347
Volume 319, Part 3, 30 January 2024, 117347
Bile acids metabolism involved in the beneficial effects of Danggui Shaoyao San via gut microbiota in the treatment of CCl4 induced hepatic fibrosis
Yanhui Zhao a,1, Min Zhao a,1, Yumeng Zhang a, Zixuan Fu a, Tong Jin a, Jiaxi Song b, Yihe Huang c, Chunjie Zhao a,*, Miao Wang
doi : 10.1016/j.jep.2023.117383
Volume 319, Part 3, 30 January 2024, 117383
Mulberry leaf multi-components exert hypoglycemic effects through regulation of the PI-3K/Akt insulin signaling pathway in type 2 diabetic rats
Yue Zhang 1, Liang Li 1, Tao Chai , Han Xu , Hong-yan Du , Yan Jiang
doi : 10.1016/j.jep.2023.117307
Volume 319, Part 3, 30 January 2024, 117307
Catalpol rescues LPS-induced cognitive impairment via inhibition of NF-Κb-regulated neuroinflammation and up-regulation of TrkB-mediated BDNF secretion in mice
Weiqing Hu a, Li Zou b, Ningxi Yu a, Zhizhongbin Wu a, Wei Yang a, Tianyue Wu a, Yulin Liu a, Yu Pu a, Yunbing Jiang a, Jifeng Zhang a, Huifeng Zhu a, Fang Cheng c,**, Shan Feng
doi : 10.1016/j.jep.2023.117345
Volume 319, Part 3, 30 January 2024, 117345
