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Efficacy and safety of the traditional herbal medication Chai-Ling-Tang (in China), Siryung-tang (in Republic of Korea) or Sairei-To (in Japan)
Christian Bailly
doi : 10.1016/j.jep.2023.117127
Volume 319, Part 1, 30 January 2024, 117127
Review of traditional uses, phytochemistry and pharmacology of Tibetan Medicine tangchong
Tianru Wang a,1, Qiuyue Li b,1, Ziyu Zhou a, Jia Liu c, Yiwen Tao a, Yi Zhang c, Yong Zeng a,***, Sanyin Zhang c,**, Jinsong Su
doi : 10.1016/j.jep.2023.117129
Volume 319, Part 1, 30 January 2024, 117129
Traditional uses, phytochemistry, pharmacology, applications, and quality control of Gastrodia elata Blume: A comprehensive review
Meng-qi Gong , Fei-fan Lai , Jian-zhen Chen , Xiao-hong Li , Ya-jie Chen , Yu He
doi : 10.1016/j.jep.2023.117128
Volume 319, Part 1, 30 January 2024, 117128
Saponins derived from Gynostemma pentaphyllum regulate triglyceride and cholesterol metabolism and the mechanisms: A review
Peng Xie , Hao-Tian Luo , Wen-Jing Pei , Man-Yu Xiao , Fang-Fang Li , Yu-Long Gu **, Xiang-Lan Piao
doi : 10.1016/j.jep.2023.117186
Volume 319, Part 1, 30 January 2024, 117186
Efficacy and potential mechanisms of the main active ingredients of astragalus mongholicus in animal models of liver fibrosis: A systematic review and meta-analysis
Lijuan Dan a,1, Yanwei Hao b,1, Hongfei Song a, Tianyuan Wang c, Jia Li a, Xiaoyan He a, Yue Su
doi : 10.1016/j.jep.2023.117198
Volume 319, Part 1, 30 January 2024, 117198
An integrated strategy for rapid discovery and identification of the potential effective fragments of polysaccharides from Saposhnikoviae Radix
Jie Li a, Meng Sun a, Chang Xu a, Chang Zhou a, Shu-jin Jing a, Yan-yan Jiang a,b,**, Bin Liu
doi : 10.1016/j.jep.2023.117099
Volume 319, Part 1, 30 January 2024, 117099
Antidiabetic effects of polyherbal mixture made of Centaurium erythraea, Cichorium intybus and Potentilla erecta
Aleksandra Petrovi´c a,*, Vi?snja Madi´c a, Gordana Stojanovi´c b, Ivana Zlatanovi´c b, Bojan Zlatkovi´c a, Perica Vasiljevi´c a, Ljubi?sa ?or?evi´c
doi : 10.1016/j.jep.2023.117032
Volume 319, Part 1, 30 January 2024, 117032
Identifying hepatoprotective mechanism and effective components of Yinchenzhufu decoction in chronic cholestatic liver injury using a comprehensive strategy based on metabolomics, molecular biology, pharmacokinetics, and cytology
Yuanyuan Li a,1, Xiaotian Peng a,1, Guofeng Wang a,1, Bin Zan a, Yahang Wang a, Juan Zou a, Tian Tian a, Qian Meng a, Rong Shi a, Tianming Wang a, Jiasheng Wu a,**, Yueming Ma
doi : 10.1016/j.jep.2023.117060
Volume 319, Part 1, 30 January 2024, 117060
Spectrum–effect relationship combined with bioactivity evaluation to discover the main anxiolytic active components of Baihe Dihuang decoction
Lin Tang a,1, Hong-Qing Zhao b,1, Hui Yang a, Chao Hu a, Si-jing Ma c, Wang-Zhong Xiao a, Yu-hui Qing b, Lei Yang a, Rong-Rong Zhou c,*, Jian Liu a,**, Shui-Han Zhang
doi : 10.1016/j.jep.2023.117090
Volume 319, Part 1, 30 January 2024, 117090
Efficacy and potential therapeutic mechanism of Weiwei decoction on Spasmolytic polypeptide-expressing metaplasia in Helicobacter pylori-infected and Atp4a-knockout mice
Xinxin Hong a,1, Haiwen Li a,1, Yandan Lin b, Liuru Luo b, Weijun Xu a, Jianyuan Kang a, Jingwei Li a, Bin Huang a, Yifei Xu a, Huafeng Pan c,**, Shaoju Guo
doi : 10.1016/j.jep.2023.117062
Volume 319, Part 1, 30 January 2024, 117062
Ginsenoside Rg1 alleviates ANIT-induced cholestatic liver injury by inhibiting hepatic inflammation and oxidative stress via SIRT1 activation
Qianyan Gao a, Guodong Li a, Yue Zu a, Yanjiao Xu a, Congyi Wang b, Dong Xiang a, Wenxi He a, Tianze Shang a, Xinwei Cheng a, Dong Liu a,*, Chengliang Zhang
doi : 10.1016/j.jep.2023.117089
Volume 319, Part 1, 30 January 2024, 117089
Isomaculosidine facilitates NLRP3 inflammasome activation by promoting mitochondrial reactive oxygen species production and causes idiosyncratic liver injury
Wei Shi a,b,c,1, Tingting Liu c,e,1, Huijie Yang a,1, Jia Zhao c, Ziying Wei a, Yujiao Huang a, Zhiyong Li b, Hui Li a, Longxin Liang c, Xiaorong Hou c, Yuanyuan Chen c, Yuan Gao b,***, Zhaofang Bai c,d,**, Xiaohe Xiao c
doi : 10.1016/j.jep.2023.117063
Volume 319, Part 1, 30 January 2024, 117063
Gardenia extract protects against intrahepatic cholestasis by regulating bile acid enterohepatic circulation
Shasha Qin a,1, Jingzhuo Tian a,1, Yong Zhao a, Lianmei Wang a, Jinyu Wang b, Suyan Liu a, Jing Meng a, Fang Wang a, Chenyue Liu a, Jiayin Han a, Chen Pan a, Yushi Zhang a, Yan Yi a, Chunying Li a, Meiting Liu a, Aihua Liang
doi : 10.1016/j.jep.2023.117083
Volume 319, Part 1, 30 January 2024, 117083
Optimal compatibility proportional screening of Trichosanthis Pericarpium - Trichosanthis Radix and its anti - Inflammatory components effect on experimental zebrafish and coughing mice
Pei Liu a,*,1, Xiao-ying Tan a,1, Huang-qin Zhang a,b, Ke-lei Su b, Er-xin Shang a, Qing-ling Xiao b, Sheng Guo a, Jin-ao Duan
doi : 10.1016/j.jep.2023.117096
Volume 319, Part 1, 30 January 2024, 117096
High-resolution neuraminidase inhibition profiling of Arnebia euchroma (Royle) I.M. Johnst. based on HR-MS and target isolation: An example study of anti-infectious constituents in traditional Chinese medicine
Yuheng Huang a,1, Xiaoxin Guo a,1, Zhen Wang a,1, Cong Yin d, Mu Chen a, Jiaming Xie a, Ning Li c, Zhengchao Tu a, Juan Li d, Jiaqing Cao a, Zhengjin Jiang a, Weihuan Huang b,**, Haiyan Tian
doi : 10.1016/j.jep.2023.117074
Volume 319, Part 1, 30 January 2024, 117074
The effect and mechanism of Qingre Huashi formula in the treatment of chronic hepatitis B with Gan-dan-shi-Re syndrome: An integrated transcriptomic and targeted metabolomic analysis
Yiyu Lu a,1, Chaoqun Zhao b,1, Chengbao Wang c, Hong Cai d, Yuting Hu a, Long Chen b, Shanghai Yu b, Huiming Zhu f, Ping Liu b, Wang Wan’e e,2,*, Hua Zhang
doi : 10.1016/j.jep.2023.117092
Volume 319, Part 1, 30 January 2024, 117092
Anticholinesterase and antioxidant activity of Drynaria quercifolia and its ameliorative effect in scopolamine-induced memory impairment in mice
Rafia Ferdous a, Md. Badrul Islam b, Md. Yusuf Al-Amin a, Anik Kumar Dey a, Md. Omar Ali Mondal c, Md. Nurul Islam d, AHM Khurshid Alam a, Aziz Abdur Rahman a, Md. Golam Sadik
doi : 10.1016/j.jep.2023.117095
Volume 319, Part 1, 30 January 2024, 117095
Isolation of indole alkaloids and a new norneolignan of hydroethanol extract from the stem barks of Aspidosperma nitidum Benth: Preclinical evaluation of safety and anti-inflammatory and healing properties
Manoela Torres-Rˆego a,c, Patr?cia Coelho do Nascimento Nogueira b, Sarah Pollyana Dias dos Santos a, Alessandra Daniele-Silva c, Felipe França Cavalcanti a,c, Cinthya Iamile Frithz Brand?ao de Oliveira d, Hugo Alexandre Oliveira Rocha e, Matheus de Freitas Fernandes-Pedrosa c, Edilberto Rocha Silveira b, Renata Mendonça Ara?jo
doi : 10.1016/j.jep.2023.117076
Volume 319, Part 1, 30 January 2024, 117076
Hypericum roeperianum bark extract suppresses breast cancer proliferation via induction of apoptosis, downregulation of PI3K/Akt/mTOR signaling cascade and reversal of EMT
Michel-Gael F. Guefack a,b, Debojit Talukdar a, Rimi Mukherjee a, Subhabrata Guha a, Debarpan Mitra a, Depanwita Saha a, Gaurav Das a, François Damen c, Victor Kuete b,**, Nabendu Murmu
doi : 10.1016/j.jep.2023.117093
Volume 319, Part 1, 30 January 2024, 117093
Xihuang pill ameliorates colitis in mice by improving mucosal barrier injury and inhibiting inflammatory cell filtration through network regulation
Meng-Lei Hu a,b,c,d,e,f, Qian-Zan Liao a,b,c,d,e,f, Bo-Tong Liu a,b,c,d,e,f, Kai Sun b,c,d,e, f, Chun-Shui Pan b,c,d,e,f, Xiao-Yi Wang a,b,c,d,e,f, Li Yan b,c,d,e,f, Xin-Mei Huo a,b,c,d,e,f , Xian-Qun Zheng a,b,c,d,e,f, Yuan Wang g, Li-Jun Zhong h, Jian Liu a,c,d,e,f, Lin He a,c,d,e,f,**, Jing-Yan Han
doi : 10.1016/j.jep.2023.117098
Volume 319, Part 1, 30 January 2024, 117098
Study on quality difference between Belamcanda chinensis (L.) DC and Iris tectorum Maxim. based on chemical chromatogram analysis, biological activity evaluation and in vivo distribution rule
Hao Xiong a, Yuanfeng Yang a, Wenhui Guo a, Jinbin Yuan a, Wuliang Yang a,**, Meng Gao
doi : 10.1016/j.jep.2023.117091
Volume 319, Part 1, 30 January 2024, 117091
The protective role of Achyranthes aspera extract against cisplatin-induced nephrotoxicity by alleviating oxidative stress, inflammation, and PANoptosis
Song-Yi Lin a, Chia-Lin Chang d,e,f, Kuo-Tong Liou b,h,i, Yao-Kai Kao a, Yea-Hwey Wang c, Cher-Chia Chang g, Terry B.J. Kuo a, Hung-Tse Huang b, Cheryl C.H. Yang a,**, Chia-Ching Liaw b,***, Yuh-Chiang Shen
doi : 10.1016/j.jep.2023.117097
Volume 319, Part 1, 30 January 2024, 117097
Preliminary study on the material basis and mechanism underlying uric acid reduction by Thlaspi arvense L.
Xiumei Ke a,1, Xuan Yang b,1, Chao Hou b, Yunhong Wang c, YiFei Zhou b, Tongxuan Wu d, Rongping Yang b,*
doi : 10.1016/j.jep.2023.116814
Volume 319, Part 1, 30 January 2024, 116814
The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/ROCK1 signalling pathway
Liu Zhou , Yifei Yang , Xiaotong Fu , Bing Xia , Chun Li , Chenna Lu , Ying Qi , Haijing Zhang *, Ting Liu
doi : 10.1016/j.jep.2023.117100
Volume 319, Part 1, 30 January 2024, 117100
The therapeutic principle of combined clearing heat and resolving toxin plus TACE on primary liver cancer: A systematic review and meta-analysis
Yuyao Wang d,1, Wanfu Lin c, Guokai Huang c, Shuchang Nie c, Qin Yu a, Fenggang Hou b,**, Shaoqi Zong
doi : 10.1016/j.jep.2023.117072
Volume 319, Part 1, 30 January 2024, 117072
Effects and mechanism of extracts rich in phenylpropanoids-polyacetylenes and polysaccharides from Codonopsis Radix on improving scopolamine-induced memory impairment of mice
Qi Xie , Xianrun Hu , Xiang Zhao , Zedong Xiang , Qianping Chen , Zhejun Xie , Hanxue Wang , Yonglin Zhao , Xuemei Cheng , Changhong Wang
doi : 10.1016/j.jep.2023.117106
Volume 319, Part 1, 30 January 2024, 117106
Extract of Astragali Radix and Solanum nigrum Linne regulates microglia and macrophage polarization and inhibits the growth and infiltration of C6 glioblastoma
Mingxue Shen a, Suo Liu a, Qin Wei a, Xiong Zhang a, Shiyu Wen a, Runze Qiu a,**, Yingbin Li b,***, Hongwei Fan
doi : 10.1016/j.jep.2023.117067
Volume 319, Part 1, 30 January 2024, 117067
Analysis of pharmacodynamic components, targets and synergistic action mechanism of Fuyuan Shenghua granule for the treatment of medical-induced incomplete abortion based on network pharmacology
Qi-qiang Zhang a,1, Xue-mei Di a,b,1, Xiang Cao a, Yonghong Nie b, Wen Shuai b, Jun Li c,**, Hai Zhang
doi : 10.1016/j.jep.2023.117118
Volume 319, Part 1, 30 January 2024, 117118
Naoxueshu oral liquid promotes hematoma absorption by targeting CD36 in M2 microglia via TLR4/MyD88/NF-κB signaling pathway in rats with intracerebral hemorrhage
Ruoqi Li a, Meiying Song a, Yingyi Zheng a, Jiaxue Zhang a, Shanshan Zhang a, Xiang Fan a,b,
doi : 10.1016/j.jep.2023.117116
Volume 319, Part 1, 30 January 2024, 117116
Diuretic activity evaluation and chemical composition analysis of Hedyotis scandens extract from Mizoram, India, in rat models
Elizabeth Vanlalruati Ngamlai a, R.B. Pradhan a, P.C. Lalbiaknii a, Vanlalhruaii Ralte b,*, F. Lalnunmawia a, P.C. Vanlalhluna b, S.K. Mehta
doi : 10.1016/j.jep.2023.117079
Volume 319, Part 1, 30 January 2024, 117079
Juvenile toxicity study of deer antler extract in rats
Jinsoo Lee a,b, Byung-Cheol Han c, Woojin Kim a, Seung-Hyuk Shin d, Ji-Seong Jeong a, Quah Yixian a, Wook-Joon Yu
Quantitative proteomics based bioactive proteins discovery and quality control of medicinal leeches
Fu-Gui Li a, Xin-Yue Shi a, Liu Yang a, Xu Lu a, Yan Qi b, Ping Li a,***, Hua Yang a,**, Wen Gao
doi : 10.1016/j.jep.2023.117117
Volume 319, Part 1, 30 January 2024, 117117
Sceletium tortuosum-derived mesembrine significantly contributes to the anxiolytic effect of Zembrin®, but its anti-depressant effect may require synergy of multiple plant constituents
doi : 10.1016/j.jep.2023.117113
Volume 319, Part 1, 30 January 2024, 117113
Effects and mechanism of Kedaling tablets for atherosclerosis treatment based on network pharmacology, molecular docking and experimental study
doi : 10.1016/j.jep.2023.117108
Volume 319, Part 1, 30 January 2024, 117108
Multimodal investigation reveals the neuroprotective mechanism of Angong Niuhuang pill for intracerebral hemorrhage: Converging bioinformatics, network pharmacology, and experimental validation
doi : 10.1016/j.jep.2023.117045
Volume 319, Part 1, 30 January 2024, 117045
Chemical profiling of Shengmai injection, tissue distribution and pharmacokinetic characteristics of ginsenosides after intravenous dosing Shengmai injection in rats with cerebral ischemia
Huanhuan Wang a,c,1, Liying Tang a,1, Shaowei Hu a,1, Xixian Kong a, Yi Ouyang a, Dong Zhang a, Yi Zhang a, Shihuan Tang a, Hongwei Wu a,*, Hongjun Yang
doi : 10.1016/j.jep.2023.117119
Volume 319, Part 1, 30 January 2024, 117119
Based on spinal central sensitization creating analgesic screening approach to excavate anti-neuropathic pain ingredients of Corydalis yanhusuo W.T.Wang
Meng-Yuan Zhou a,1, Chang-Heng Yao a,1, Yu-Jie Yang a, Xue Li a, Jin Yang a, Ji-Hua Liu a,b,**, Bo-Yang Yu a,b,***, Wen-Ling Dai
doi : 10.1016/j.jep.2023.117084
Volume 319, Part 1, 30 January 2024, 117084
Neuroprotective mechanisms of defatted walnut powder against scopolamine-induced Alzheimer's disease in mice revealed through metabolomics and proteomics analyses
Xiajing Xu a, Yong Ding a, Meihan Liu a, Xuanmeng Zhang a, Dongmei Wang b, Yingni Pan a, Shumeng Ren a,*, Xiaoqiu Liu
doi : 10.1016/j.jep.2023.117107
Volume 319, Part 1, 30 January 2024, 117107
Revealing the mechanism of Zanthoxylum armatum DC. extract-induced liver injury in mice based on lipidomics
Nannan Yang a, Jian Zhang a, Jiafu Guo a, Qiwen Xiang a, Yan Huang b, Jiayu Wen a, Qiuyan Liu a, Tingting Hu a, Yan Chen a,b,*, Chaolong Rao
doi : 10.1016/j.jep.2023.117086
Volume 319, Part 1, 30 January 2024, 117086
Hyperglycemia effect of Pinctada martensii hydrolysate in diabetic db/db mice
Jiayun Li a,b,c,1, Yuanqing Wei a,b,c,1, Siying Huang a,b,c, Shenghan Yan f, Binyuan Zhao f, Xinzhi Wang b,c, Jipeng Sun g, Tianbao Chen e,h, Yueyang Lai d,**, Rui Liu
doi : 10.1016/j.jep.2023.117104
Volume 319, Part 1, 30 January 2024, 117104
Jianpi Shengqing Huazhuo Formula improves abnormal glucose and lipid metabolism in obesity by regulating mitochondrial biogenesis
Wenkai Wang a,b, Shanshan Chen a,b, Shuting Xu a,b, Guangyi Liao a,b, Weihao Li a,b, Xiao Yang a,b, Tingting Li a,b, Huifen Zhang c, Huanhuan Huang c, Yuqing Zhou c, Huafeng Pan a,b, Chuanquan Lin a,b,*
doi : 10.1016/j.jep.2023.117102
Volume 319, Part 1, 30 January 2024, 117102
Zhisou powder displays therapeutic effect on chronic bronchitis through inhibiting PI3K/Akt/HIF-1α/VEGFA signaling pathway and reprograming metabolic pathway of arachidonic acid
Yahui Dong a, Yang Liu a, Jie Tang b, Jiahui Du a, Xuzhen Zhuang a, Song Tan a, Ye Yang a,c,d,**, Dengke Yin
doi : 10.1016/j.jep.2023.117110
Volume 319, Part 1, 30 January 2024, 117110
An Andrographis paniculata Burm. Nees extract standardized for three main Andrographolides prevents house dust mite-induced airway inflammation, remodeling, and hyperreactivity by regulating Th1/Th2 gene expression in mice
Ibrahim Sulaiman a,1, Emmanuel Oshiogwe Okwuofu a, Norhafizah Mohtarrudin b, Jonathan Chee Woei Lim a, Johnson Stanslas
doi : 10.1016/j.jep.2023.117082
Volume 319, Part 1, 30 January 2024, 117082
A novel strategy of integrating network pharmacology and transcriptome reveals antiapoptotic mechanisms of Buyang Huanwu Decoction in treating intracerebral hemorrhage
Menghan Cheng a,c,d,e, Teng Li a,b,c,d,e, En Hu a,b,c,d,e, Qiuju Yan a,c,d,e, Haigang Li f, Yang Wang a,b,c,d,e, Jiekun Luo a,b,c,d,e, Tao Tang
doi : 10.1016/j.jep.2023.117123
Volume 319, Part 1, 30 January 2024, 117123
Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-κB trajectories
Nermeen B. Ali a, Sherihan Salaheldin Abdelhamid Ibrahim b, Muhammad A. Alsherbiny a,c,d, Eman Sheta e, Riham A. El-Shiekh a,*, Rehab M. Ashour a, Amira A. El-Gazar f, Ghada M. Ragab g, Sabah H. El-Gayed a,h, Chun Guang Li d, Essam Abdel-Sattar
doi : 10.1016/j.jep.2023.117115
Volume 319, Part 1, 30 January 2024, 117115
Taraxacum coreanum Nakai extract attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier dysfunction in Caco-2Â cells
Seok Hee Han a, Hak-Dong Lee b, Sanghyun Lee b,c,**, Ah Young Lee
doi : 10.1016/j.jep.2023.117105
Volume 319, Part 1, 30 January 2024, 117105
Polygonum cuspidatum Sieb. et Zucc. Extracts improve sepsis-associated acute kidney injury by inhibiting NF-κB-mediated inflammation and pyroptosis
Yuan Yang a,1, Jia Xu a,1, Jie Tu b,1, Yi Sun c, Cong Zhang c, Zhenpeng Qiu c,d,*, Han Xiao a
doi : 10.1016/j.jep.2023.117101
Volume 319, Part 1, 30 January 2024, 117101
Buyang Huanwu Decoction alleviates blood stasis, platelet activation, and inflammation and regulates the HMGB1/NF-κB pathway in rats with pulmonary fibrosis
Yuenan Feng a,1, Linfeng Dai b,1, Yanli Zhang a,1, Simiao Sun c,1, Shan Cong d,1, Shuang Ling e, Huan Zhang
doi : 10.1016/j.jep.2023.117088
Volume 319, Part 1, 30 January 2024, 117088
Gypenoside XVII inhibits ox-LDL-induced macrophage inflammatory responses and promotes cholesterol efflux through activating the miR-182-5p/HDAC9 signaling pathway
Wen-Yi Deng a,1, Cheng-Long Zhou b,1, Meng-Ya Zeng
doi : 10.1016/j.jep.2023.117070
Volume 319, Part 1, 30 January 2024, 117070
Hyperglycemia effect of Pinctada martensii hydrolysate in diabetic db/db mice
Jiayun Li a,b,c,1, Yuanqing Wei a,b,c,1, Siying Huang a,b,c, Shenghan Yan f, Binyuan Zhao f, Xinzhi Wang b,c, Jipeng Sun g, Tianbao Chen e,h, Yueyang Lai d,**, Rui Liu
doi : 10.1016/j.jep.2023.117104
Volume 319, Part 1, 30 January 2024, 117104
Jianpi Shengqing Huazhuo Formula improves abnormal glucose and lipid metabolism in obesity by regulating mitochondrial biogenesis
Wenkai Wang a,b, Shanshan Chen a,b, Shuting Xu a,b, Guangyi Liao a,b, Weihao Li a,b, Xiao Yang a,b, Tingting Li a,b, Huifen Zhang c, Huanhuan Huang c, Yuqing Zhou c, Huafeng Pan a,b, Chuanquan Lin a,b,*
doi : 10.1016/j.jep.2023.117102
Volume 319, Part 1, 30 January 2024, 117102
Zhisou powder displays therapeutic effect on chronic bronchitis through inhibiting PI3K/Akt/HIF-1α/VEGFA signaling pathway and reprograming metabolic pathway of arachidonic acid
Yahui Dong a, Yang Liu a, Jie Tang b, Jiahui Du a, Xuzhen Zhuang a, Song Tan a, Ye Yang a,c,d,**, Dengke Yin
doi : 10.1016/j.jep.2023.117110
Volume 319, Part 1, 30 January 2024, 117110
An Andrographis paniculata Burm. Nees extract standardized for three main Andrographolides prevents house dust mite-induced airway inflammation, remodeling, and hyperreactivity by regulating Th1/Th2 gene expression in mice
Ibrahim Sulaiman a,1, Emmanuel Oshiogwe Okwuofu a, Norhafizah Mohtarrudin b, Jonathan Chee Woei Lim a, Johnson Stanslas
doi : 10.1016/j.jep.2023.117082
Volume 319, Part 1, 30 January 2024, 117082
A novel strategy of integrating network pharmacology and transcriptome reveals antiapoptotic mechanisms of Buyang Huanwu Decoction in treating intracerebral hemorrhage
Menghan Cheng a,c,d,e, Teng Li a,b,c,d,e, En Hu a,b,c,d,e, Qiuju Yan a,c,d,e, Haigang Li f, Yang Wang a,b,c,d,e, Jiekun Luo a,b,c,d,e, Tao Tang
doi : 10.1016/j.jep.2023.117123
Volume 319, Part 1, 30 January 2024, 117123
Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-κB trajectories
Nermeen B. Ali a, Sherihan Salaheldin Abdelhamid Ibrahim b, Muhammad A. Alsherbiny a,c,d, Eman Sheta e, Riham A. El-Shiekh a,*, Rehab M. Ashour a, Amira A. El-Gazar f, Ghada M. Ragab g, Sabah H. El-Gayed a,h, Chun Guang Li d, Essam Abdel-Sattar
doi : 10.1016/j.jep.2023.117115
Volume 319, Part 1, 30 January 2024, 117115
Taraxacum coreanum Nakai extract attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier dysfunction in Caco-2Â cells
Seok Hee Han a, Hak-Dong Lee b, Sanghyun Lee b,c,**, Ah Young Lee
doi : 10.1016/j.jep.2023.117105
Volume 319, Part 1, 30 January 2024, 117105
Polygonum cuspidatum Sieb. et Zucc. Extracts improve sepsis-associated acute kidney injury by inhibiting NF-κB-mediated inflammation and pyroptosis
Yuan Yang a,1, Jia Xu a,1, Jie Tu b,1, Yi Sun c, Cong Zhang c, Zhenpeng Qiu c,d,*, Han Xiao a
doi : 10.1016/j.jep.2023.117101
Volume 319, Part 1, 30 January 2024, 117101
Buyang Huanwu Decoction alleviates blood stasis, platelet activation, and inflammation and regulates the HMGB1/NF-κB pathway in rats with pulmonary fibrosis
Yuenan Feng a,1, Linfeng Dai b,1, Yanli Zhang a,1, Simiao Sun c,1, Shan Cong d,1, Shuang Ling e, Huan Zhang
doi : 10.1016/j.jep.2023.117088
Volume 319, Part 1, 30 January 2024, 117088
Gypenoside XVII inhibits ox-LDL-induced macrophage inflammatory responses and promotes cholesterol efflux through activating the miR-182-5p/HDAC9 signaling pathway
Wen-Yi Deng a,1, Cheng-Long Zhou b,1, Meng-Ya Zeng
doi : 10.1016/j.jep.2023.117070
Volume 319, Part 1, 30 January 2024, 117070
Bombyx batryticatus extract activates coagulation factor â…« to promote angiogenesis in rats with cerebral ischemia/reperfusion injury
doi : 10.1016/j.jep.2023.117081
Volume 319, Part 1, 30 January 2024, 117081
Yi Mai granule improve energy supply of endothelial cells in atherosclerosis via miRNA-125a-5p regulating mitochondrial autophagy through Pink1-Mfn2-Parkin pathway
doi : 10.1016/j.jep.2023.117114
Volume 319, Part 1, 30 January 2024, 117114
Identification of bioactive components on antihemorrhoidal activity of Cistus laurifolius L. using RP-HPLC and LC-QTOF-MS
Sultan Pekacar a, Burçin ¨Ozüpek a, Esra Küpeli Akkol a,**, Hakk? Tas¸tan b, Halil Ersan c, Didem Deliorman Orhan
doi : 10.1016/j.jep.2023.117122
Volume 319, Part 1, 30 January 2024, 117122
A network pharmacology integrated serum pharmacochemistry strategy for uncovering efficacy of YXC on hepatocellular carcinoma
Ting-ting Zhou a,1, Wen-jian Zhu a,1, Hui Feng a, Yue Ni b, Zi-wen Li a, Dong-dong Sun a,c,d, Liu Li a,c,d, Jia-ni Tan a,c,d, Cheng-tao Yu a,c,d, Wei-xing Shen a,c,d,*, Hai-bo Cheng
doi : 10.1016/j.jep.2023.117125
Volume 319, Part 1, 30 January 2024, 117125
Distribution profiles of phenolic compounds in a cultivar of wampee (Clausena lansium (Lour.) Skeels) fruits and in vitro anti-inflammatory activity
Fanke Zeng , Mianhong Chen , Shengtao Yang , Ruyi Li *, Xuli Lu , Li Zhang , Tinghui Chen , Shaodan Peng , Wei Zhou , Jihua Li
doi : 10.1016/j.jep.2023.117168
Volume 319, Part 1, 30 January 2024, 117168
Corydalis saxicola Bunting total alkaloids improve NAFLD by suppressing de novo lipogenesis through the AMPK-SREBP1 axis
Yating Guo a,1, Qiushuang Sun a,1, Shijiao Wang b, Mengdi Zhang c, Yuanyuan Lei b, Jiejie Wu a, Xinhong Wang b, Wenjun Hu b, Haitao Meng d, Zhiyu Li e, Luzhou Xu f,***, Fang Huang a,**, Zhixia Qiu
doi : 10.1016/j.jep.2023.117162
Volume 319, Part 1, 30 January 2024, 117162
Anti-hypertension effect of Wuwei Jiangya decoction via ACE2/Ang1-7/MAS signaling pathway in SHR based on network degree-distribution analysis
Pengqian Wang a,1, Danli Hao a,1, Xingjiang Xiong
doi : 10.1016/j.jep.2023.117121
Volume 319, Part 1, 30 January 2024, 117121
Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice: Mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation
Pan Xie a,1, Lixia Chen a,1, Juan Wang a, Xuncui Wang a, Shaojie Yang a,b,*, Guoqi Zhu
doi : 10.1016/j.jep.2023.117165
Volume 319, Part 1, 30 January 2024, 117165
Ameliorative effect of Alangium chinense (Lour.) Harms on rheumatoid arthritis by reducing autophagy with targeting regulate JAK3-STAT3 and COX-2 pathways
Ting Xiao a,b,c,*, Xingyan Cheng a,b,c, Yuan Zhi a,b,c, Fangfang Tian a,b,c, Ai Wu a,b,c, Feilong Huang a,b,c, Ling Tao a,b,c, Zhenghong Guo d,**, Xiangchun Shen
doi : 10.1016/j.jep.2023.117133
Volume 319, Part 1, 30 January 2024, 117133
Development and validation of a simple and rapid UPLC-MS/MS method for loganin and its application in pharmacokinetic and tissue distribution studies
Fan Zhang a,b,1, Yu Yan b,1, Kang Ding b, Wen-Wen Lian b, Li Li c, Wen-Ping Wang b, Cong-Yuan Xia b, Hua Yang d, Jun He b,*, Wei-Ku Zhang b,**, Jie-Kun Xu
doi : 10.1016/j.jep.2023.117130
Volume 319, Part 1, 30 January 2024, 117130
Neuroprotective Effect of Zishen Huoxue Decoction treatment on Vascular Dementia by activating PINK1/Parkin mediated Mitophagy in the Hippocampal CA1 Region
Ziting Zhao a, Le Xie b, Jiayi Shi c, Tonghe Liu c, Shiliang Wang b, Jianhua Huang d, Dahua Wu b,*, Xiuli Zhang
doi : 10.1016/j.jep.2023.117172
Volume 319, Part 1, 30 January 2024, 117172
The anticonvulsant effect of saiga horn on febrile seizures by regulating brain serotonin content and inhibiting neuroinflammation
Jinhu Li a,1, Xiang Yao a,1, Yurou Wu a, Chengwei Wang a, Jincheng Yang a, Chunjie Wu
doi : 10.1016/j.jep.2023.117180
Volume 319, Part 1, 30 January 2024, 117180
Acute and 90-day toxicological safety assessment of Shang-Ke-Huang-Shui lotion in New Zealand White rabbits
Fanghao Zheng *, Tingting Zhao, Zhenyang Liu
doi : 10.1016/j.jep.2023.117027
Volume 319, Part 1, 30 January 2024, 117027
Evaluation of the toxicity of the hydroethanolic extract of the stem bark of Virola elongata (Benth.) Warb. in in vitro and in vivo models
Michellen Santos de Carvalho a, Guilherme Vieira Botelho de Almeida b, Karuppusamy Arunachalam c,d, Edson Moleta Colodel e, Camilo Eduardo Barcenas Olaya e, Domingos Tabajara de Oliveira Martins
doi : 10.1016/j.jep.2023.117171
Volume 319, Part 1, 30 January 2024, 117171
Isolation and characterization of bioactive components from hydroalcoholic extract of Cymbopogon jwarancusa (Jones) Schult. to evaluate its hepatoprotective activity
Sajida Sumaiya a, Aisha Siddiqui a,*, Shahid Shah Chaudhary b, Mohd Aslam a, Sayeed Ahmad c, Mairaj Ahmed Ansari
doi : 10.1016/j.jep.2023.117185
Volume 319, Part 1, 30 January 2024, 117185
Efficacy and mechanism study of Baichanting compound, a combination of Acanthopanax senticosus (Rupr. and Maxim.) Harms, Paeonia lactiflora Pall and Uncaria rhynchophylla (Miq.) Miq. ex Havil, on Parkinson's disease based on metagenomics and metabolomics
doi : 10.1016/j.jep.2023.117182
Volume 319, Part 1, 30 January 2024, 117182
Essential oil from Inula japonica Thunb. And its phenolic constituents ameliorate pulmonary injury and fibrosis in bleomycin-treated mice
Fan Wei a,b,1, Yuzhen Yin a,b,1, Jie Li a,1, Yibo Chang a,c, Shuyuan Zhang a, Wenyu Zhao a,*, Xiaochi Ma
doi : 10.1016/j.jep.2023.117169
Volume 319, Part 1, 30 January 2024, 117169
Shen-Ling-Bai-Zhu-San alleviates the imbalance of intestinal homeostasis in dextran sodium sulfate-induced colitis mice by regulating gut microbiota and inhibiting the NLRP3 inflammasome activation
Qianru Gao a, Weiyi Tian b, Huabing Yang a, Haiming Hu a, Junping Zheng a, Xiaowei Yao a, Baifei Hu a,**, Hongtao Liu
doi : 10.1016/j.jep.2023.117136
Volume 319, Part 1, 30 January 2024, 117136
Yuanzhi powder facilitated Aβ clearance in APP/PS1 mice: Target to the drainage of glymphatic system and meningeal lymphatic vessels
Jiaxin Li a, Yanwei Hao a, Shaofeng Wang a, Wei Li b, Shengnan Yue a, Xueqing Duan a, Yuting Yang c, Bin Li
doi : 10.1016/j.jep.2023.117195
Volume 319, Part 1, 30 January 2024, 117195
Qishen granule attenuates doxorubicin-induced cardiotoxicity by protecting mitochondrial function and reducing oxidative stress through regulation of Sirtuin3
Jingmei Zhang a,1, Weili Li b,1, Siming Xue a,1, Pengrong Gao b, Hui Wang a, Huan Chen a, Yiqin Hong a, Qianbin Sun b, Linghui Lu b,c,d,**, Yong Wang b,c,d,***, Qiyan Wang
doi : 10.1016/j.jep.2023.117134
Volume 319, Part 1, 30 January 2024, 117134
Panax notoginseng saponins inhibits oxidative stress- induced human nucleus pulposus cell apoptosis and delays disc degeneration in vivo and in vitro
Danqing Guo a,*, Miao Yu b, Huizhi Guo c, Min Zeng d, Yang Shao e, Wei Deng e, Qiuli Qin e, Yongxian Li c, Shuncong Zhang
doi : 10.1016/j.jep.2023.117166
Volume 319, Part 1, 30 January 2024, 117166
Buddlejasaponin IVb ameliorates ferroptosis of dopaminergic neuron by suppressing IRP2-mediated iron overload in Parkinson's disease
Qiang-Ming Li a,1, Tong Xu a,1, Xue-Qiang Zha a, Xiao-Wen Feng c, Feng-Yun Zhang b,*, Jian-Ping Luo
doi : 10.1016/j.jep.2023.117196
Volume 319, Part 1, 30 January 2024, 117196
Phytochemical composition, toxicological profiling and effect on pup birth weight of Corchorus olitorius leaf extract in rats: Implications for fetal macrosomia control
Onyinye Mkpola Ukpai a, Solomon Nnah Ijioma a, Kingsley Kanu b, Daniel Orieke c, Peace Amarachi Chinedu-Ndukwe a, Kingsley Chijioke Ugwuanyi a, Eziuche Amadike Ugbogu
doi : 10.1016/j.jep.2023.117170
Volume 319, Part 1, 30 January 2024, 117170
Cold pressed Pinus halepensis Mill. seed oil for potential health applications: Analgesic, anti-inflammatory effects, and assessment of inflammatory mediators by RT-qPCR in skin wound healing
Sihem Ait Atmane a,*, Muhammet Burak Bat?r b, Zeynep Aksoylu ¨Ozbek c,d, Pelin Günç Erg¨onül c, Erdal Balcan b, Djedjiga Ait Eldjoudi a, Evrim ¨Ozkale b, Noureddine Bribi a, Bachra Khettal
doi : 10.1016/j.jep.2023.117157
Volume 319, Part 1, 30 January 2024, 117157
Zhizi-Chuanxiong herb pair alleviates atherosclerosis progression in ApoE−/− mice by promoting the methylation of FGFR3 to inhibit MAPK/ERK-mediated apoptosis
Yan Zhang a,b,1, Dandan Li c,1, Zijun Jia d,a, Jun Mei a,b, Ya Wang a, Ying Zhang a,b,**, Qingbing Zhou a,b,*, Fengqin Xu
doi : 10.1016/j.jep.2023.117188
Volume 319, Part 1, 30 January 2024, 117188
Ruyong formula improves thymus function of CUMS-stimulated breast cancer mice
Bingqian He a,1, Wenqin Guo b,c,1, Rongzhen Shi b,d,1, Robert D. Hoffman e, Qihan Luo b, Yuan-Jia Hu f,**, Jianli Gao
doi : 10.1016/j.jep.2023.117164
Volume 319, Part 1, 30 January 2024, 117164
Exploring the efficacy of various wheat bran extracts in promoting burn wound healing: A comparative analysis
Mai A.M. Ahmed a,*, Marwa F. Ali b, Nesma M. Mohamed a,c, Soad A.L. Bayoumi a, Asmaa M. Zahran d, Khalid I. Elsayh
doi : 10.1016/j.jep.2023.117174
Volume 319, Part 1, 30 January 2024, 117174
An innovative processing driven efficient transformation of rare ginsenosides enhances anti-platelet aggregation potency of notoginseng by integrated analyses of processing-(chemical) profiling-pharmacodynamics
Wenxiang Fan a, Qi Liao a, Linhong Fan a, Qi Li a,b, Longchan Liu a, Ziying Wang a, Yuqi Mei a, Linnan Li a, Li Yang a,**, Zhengtao Wang
doi : 10.1016/j.jep.2023.117126
Volume 319, Part 1, 30 January 2024, 117126
Deciphering the function of Xiangsha-Liujunzi-Tang in enhancing duodenal mucosal barrier by inhibiting MC/Tryptase/PAR-2 signaling pathway in functional dyspepsia rats
Min Bai a,b,1, Linna Zhao a,b,1, Mengya Liu a,1, Runfa Li a, Yuping Yang a, Yugui Zhang a, Xiaomei Yuan a, Yarong Li c, Yongqiang Duan c,**, Yaorong An a, Yingxia Cheng
doi : 10.1016/j.jep.2023.116715
Volume 319, Part 1, 30 January 2024, 116715
In vivo metabolism combined network pharmacology to identify anti-constipation constituents in Aloe barbadensis Mill
doi : 10.1016/j.jep.2023.117200
Volume 319, Part 1, 30 January 2024, 117200
Gleditsiae sinensis fructus Pills combined with Jujubae fructus attenuate chronic bronchitis via regulation of AGE-RAGE signaling pathway
Chang-chang Wang a,1, Le Kang a,b,1, Bei-lei Zuo a, Xin Peng a, Hong-wei Li a,b,c, Ning Zhou a,b,c,**, Kai Li
doi : 10.1016/j.jep.2023.117191
Volume 319, Part 1, 30 January 2024, 117191
The oral administration of Lotus corniculatus L. attenuates acute and chronic pain models in male rats
Sajjad Jabbari a, Zainul Amiruddin Zakaria b, Davoud Ahmadimoghaddam c, Saeed Mohammadi
doi : 10.1016/j.jep.2023.117181
Volume 319, Part 1, 30 January 2024, 117181
Exploring in vitro and in vivo anti-inflammatory activities of the Thai traditional remedy Kheaw-Hom and its bioactive compound, ethyl p-methoxycinnamate, and ethnopharmacological analysis
Kanmanee Sukkasem a, Arunporn Itharat b,c,*, Krittiya Thisayakorn d, Nattapol Tangsuphoom e, Sumalee Panthong b,c, Sunita Makchuchit b,c, Janjira Inprasit b, Nuntika Prommee b, Wicheian Khoenok d, Kanjana Sriyam d, Darunee Pahusee d, Adis Tasanarong f, Buncha Ooraikul g,h, Neal M. Davies
doi : 10.1016/j.jep.2023.117131
Volume 319, Part 1, 30 January 2024, 117131
Research on the mechanism of antidepressive effect of Suanzaoren Decoction through TLR4/MyD88/NF-κB pathway and Wnt/β-catenin pathway
Yiyang Du , Tingxu Yan , Bo Wu , Bosai He **, Ying Jia
doi : 10.1016/j.jep.2023.117190
Volume 319, Part 1, 30 January 2024, 117190
Qufeng Xuanbi Formula inhibited benzo[a]pyrene-induced aggravated asthma airway mucus secretion by AhR/ROS/ERK pathway
Bo-Han Wang a,1, Ling-Ling Tang b,1, Xian-Hong Sun a,1, Qian Zhang c, Chun-Yang Liu d, Xiao-Na Zhang a, Ke-Yao Yu a, Ying Yang a, Jun Hu e, Xiao-Lu Shi a,**, Yue Wang a,***, Li Liu
doi : 10.1016/j.jep.2023.117203
Volume 319, Part 1, 30 January 2024, 117203
Modified Bushen Yiqi formula enhances antitumor immunity by reducing the chemotactic recruitment of M2-TAMs and PMN-MDSCs in Lewis lung cancer-bearing mice
Qing Kong a,b,1, Huahe Zhu a,b,1, Weiyi Gong a,b, Xiaohong Deng a,b, Baojun Liu a,b,*, Jingcheng Dong
doi : 10.1016/j.jep.2023.117183
Volume 319, Part 1, 30 January 2024, 117183
Optimized new Shengmai powder ameliorates myocardial fibrosis in rats with heart failure by inhibition of the MAPK signaling pathway
Zeyu Zhang 1, Yuwei Song 1, Xuan Zhang , Shuai Wang , Zhuangzhuang Jia , Lin Wang , Ci Wang , Xianliang Wang *, Jingyuan Mao
doi : 10.1016/j.jep.2023.117210
Volume 319, Part 1, 30 January 2024, 117210
Shenqu xiaoshi oral solution enhances digestive function and stabilizes the gastrointestinal microbiota of juvenile rats with infantile anorexia
Meng Zhao a,1, Ting Xiang b,1, Zhikui Dong c, Guorui Liu b, Pengran Wang b, Xiaoxu Qi b, Qingqing Hao a, Na Han a, Zhihui Liu a, Sikai Li a, Jun Yin a,*, Jianxiu Zhai
doi : 10.1016/j.jep.2023.117112
Volume 319, Part 1, 30 January 2024, 117112
Characterization of the glucuronidating pathway of pectolinarigenin, the major active constituent of the Chinese medicine Daji, in humans and its influence on biological activities
Peiqi Liu a,b, Qian Li b, Guanghao Zhu b, Tiantian Zhang b, Dongzhu Tu b, Feng Zhang b, Moshe Finel c, Yuqi He a,**, Guangbo Ge
doi : 10.1016/j.jep.2023.117280
Volume 319, Part 1, 30 January 2024, 117280
Network pharmacology integrated with experimental validation revealed the mechanism of Fengshi Gutong Capsule in the treatment of osteoarthritis
Yanqiu Sun a,c, Jian Liu a,c,*, Jue Wang b, Mingyu He a,c, Xiaolu Chen a,c, Li Chen
doi : 10.1016/j.jep.2023.117261
Volume 319, Part 1, 30 January 2024, 117261
Corrigendum to “Application of omics technology to investigate the mechanism underlying the role of San Hua Tang in regulating microglia polarization and blood-brain barrier protection following ischemic stroke� [J. Ethnopharmacol. 314 (2023) 116640]
Shan Luo a,b, Yuanchun Chen a, Ruoxi Zhao a, Donglai Ma c, Yanmeng Zhao d, Ying Zhang d,e, Jianming Jiang c,**, Wentao Yu
doi : 10.1016/j.jep.2023.117155
Volume 319, Part 1, 30 January 2024, 117155
Corrigendum to “Clinical efficacy of Shugan granule in the treatment of mixed anxiety-depressive disorder: A multicenter, randomized, double-blind, placebo-controlled trial� [J. Ethnopharmacol. 290 (2022) 115032]
Yang Li a, Liqi Li b, Rongjuan Guo c,*, Hua Yu d, Xinping Wang d, Baoshen Wang e, Qiufeng Wang e, Zengxiang Li f, Huixin Zhao f, Qile Temu g, Xiaochun Chen g, Yurong Zhang g, Jinlan An h, Xiaojun Cai i, Anhong Li j, Lihong Qi k, Jinlin Shang l, Huiling He m, Dongdong Yang n, Jiaming Lin o, Yuan Zhang b, Ting Zou
doi : 10.1016/j.jep.2023.117370
Volume 319, Part 1, 30 January 2024, 117370
Corrigendum to “The optimal dose of arsenic trioxide induced opposite efficacy in autophagy between K562 cells and their initiating cells to eradicate human myelogenous leukemia� [J. Ethnopharmacol. 196 (2017) 29–38]
Zhenzhen Guo 1, Mingjing Meng 1, Shengnan Geng, Zhenhua Du, Yaqiu Zheng, Jingjing Yao, Zibo Li, Guang Han, Haihong Lin **, Gangjun Du
doi : 10.1016/j.jep.2023.117391
Volume 319, Part 1, 30 January 2024, 117391
Sida cordifolia L. attenuates behavioral hypersensitivity by interfering with KIF17-NR2B signaling in rat model of neuropathic pain
Vineeta Tiwari , Siva Hemalatha
doi : 10.1016/j.jep.2023.117085
Volume 319, Part 1, 30 January 2024, 117085
Traditionally used anti-diabetic plants in Kathua district of Union Territory of Jammu and Kashmir, India
Madhvi Parasher a,b,*, Devendra Kumar Pandey a,**, R.K. Manhas
doi : 10.1016/j.jep.2023.117087
Volume 319, Part 1, 30 January 2024, 117087
Understanding mechanistic aspect of the therapeutic role of herbal agents on neuroplasticity in cerebral ischemic-reperfusion injury
Annu Bangar a, Heena Khan a, Amarjot Kaur a, Kamal Dua b,c, Thakur Gurjeet Singh
doi : 10.1016/j.jep.2023.117153
Volume 319, Part 2, 30 January 2024, 117153
A review on ethnopharmacology, phytochemistry, pharmacology and potential uses of Portulaca oleracea L.
Kun Li a,b,1, Tianshuang Xia a,1, Yiping Jiang a, Nani Wang c, Liyong Lai a, Shengyan Xu a, Xiaoqiang Yue b,**, Hailiang Xin
doi : 10.1016/j.jep.2023.117211
Volume 319, Part 2, 30 January 2024, 117211
Effect of Crocus sativus L. (saffron) and crocin in the treatment of patients with type-2 diabetes mellitus: A systematic review and meta-analysis
Pedro de Padua G. Amatto a, Lucas Chaves b, Giovana Graça Braga a,c, F´abio Carmona b,1, Ana Maria Soares Pereira
doi : 10.1016/j.jep.2023.117255
Volume 319, Part 2, 30 January 2024, 117255
Traditional uses, phytochemistry, pharmacology, and safety concerns of hawthorn (Crataegus genus): A comprehensive review
Meng Cui a, Lei Cheng a, Zhongyu Zhou a,b, Zemei Zhu a, Yinglin Liu a, Chaohai Li a, Binbin Liao a, Min Fan a,*, Baozhong Duan
doi : 10.1016/j.jep.2023.117229
Volume 319, Part 2, 30 January 2024, 117229
Cholinergic signaling of muscarinic receptors directly involves in the neuroprotection of muscone by inducing Ca2+ antagonism and maintaining mitochondrial function
Gang Shen a,b, Zongyuan Zhou c, Yanlei Guo b, Li Li b, Jin Zeng b, Jianbo Wang b,*, Junning Zhao
doi : 10.1016/j.jep.2023.117192
Volume 319, Part 2, 30 January 2024, 117192
Guizhi Fuling Formulation: A review on chemical constituents, quality control, pharmacokinetic studies, pharmacological properties, adverse reactions and clinical applications
Xinyue Liu, Lele Chen, Peng Sun, Zhaoshuang Zhan **, Jiafeng Wang
doi : 10.1016/j.jep.2023.117277
Volume 319, Part 2, 30 January 2024, 117277
The genus Actinidia Lindl. (Actinidiaceae): A comprehensive review on its ethnobotany, phytochemistry, and pharmacological properties
doi : 10.1016/j.jep.2023.117222
Volume 319, Part 2, 30 January 2024, 117222
Review of the therapeutic potential of Forsythiae Fructus on the central nervous system: Active ingredients and mechanisms of action
Leying Zhang a, Fenglong Lang b, Juan Feng a, Jue Wang
doi : 10.1016/j.jep.2023.117275
Volume 319, Part 2, 30 January 2024, 117275
Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
Suman Kumar Samanta a,b,*,1, Paramita Choudhury b,c,1, Raghuram Kandimalla b,d,e,1, Farrukh Aqil d,f, Disha N. Moholkar d,e, Ramesh C. Gupta d,e, Momita Das b, Bhaskarjyoti Gogoi g, Neelutpal Gogoi h, Partha Pratim Sarma b, Rajlakshmi Devi b,**, Narayan C. Talukdar
doi : 10.1016/j.jep.2023.117235
Volume 319, Part 2, 30 January 2024, 117235
Research progress on traditional Chinese medicine-induced apoptosis signaling pathways in ovarian cancer cells
Yu Wang a,1, Liangzhen Xie b, Fangyuan Liu b, Danni Ding a, Wei Wei a, Fengjuan Han
doi : 10.1016/j.jep.2023.117299
Volume 319, Part 2, 30 January 2024, 117299
A comprehensive review of the classical prescription Yiguan Jian: Phytochemistry, quality control, clinical applications, pharmacology, and safety profile
Changcheng Lu a,b,1, Siyuan Zhang a,b,1, Si San Lei a,b, Danni Wang a, Bo Peng a,b, Ruipeng Shi a,b, Cheong-Meng Chong a,**, Zhangfeng Zhong a,b,*, Yitao Wang
doi : 10.1016/j.jep.2023.117230
Volume 319, Part 2, 30 January 2024, 117230
Medicinal patterns of vines used in Chinese herbal medicine: a quantitative study
Yanlin Ding a,b,1, Dingping Zhao a,b,1, Tingye Wang a,b,1, Zhenyu Xu a,b, Yuxuan Fu a,b, Li Tao
doi : 10.1016/j.jep.2023.117184
Volume 319, Part 2, 30 January 2024, 117184
Herbal therapeutics for female infertility: A systematic review and meta-analysis
Ji-Yoon Hyun , Hyeon-Suk Jung , Ji-Yeun Park
doi : 10.1016/j.jep.2023.117258
Volume 319, Part 2, 30 January 2024, 117258
Mechanism of herb pair containing Astragali Radix and Spatholobi Caulis in the treatment of myelosuppression based on network pharmacology and experimental investigation
Fei Peng a,b, Wanying Hong a, Yingyu Wang a,b, Yunru Peng a,b,*, Zhijun Fang
doi : 10.1016/j.jep.2023.117178
Volume 319, Part 2, 30 January 2024, 117178
Cholinergic signaling of muscarinic receptors directly involves in the neuroprotection of muscone by inducing Ca2+ antagonism and maintaining mitochondrial function
Gang Shen a,b, Zongyuan Zhou c, Yanlei Guo b, Li Li b, Jin Zeng b, Jianbo Wang b,*, Junning Zhao
doi : 10.1016/j.jep.2023.117192
Volume 319, Part 2, 30 January 2024, 117192
Guizhi Fuling Formulation: A review on chemical constituents, quality control, pharmacokinetic studies, pharmacological properties, adverse reactions and clinical applications
Xinyue Liu, Lele Chen, Peng Sun, Zhaoshuang Zhan **, Jiafeng Wang
doi : 10.1016/j.jep.2023.117277
Volume 319, Part 2, 30 January 2024, 117277
The genus Actinidia Lindl. (Actinidiaceae): A comprehensive review on its ethnobotany, phytochemistry, and pharmacological properties
doi : 10.1016/j.jep.2023.117222
Volume 319, Part 2, 30 January 2024, 117222
Review of the therapeutic potential of Forsythiae Fructus on the central nervous system: Active ingredients and mechanisms of action
Leying Zhang a, Fenglong Lang b, Juan Feng a, Jue Wang
doi : 10.1016/j.jep.2023.117275
Volume 319, Part 2, 30 January 2024, 117275
Mahanine mediated therapeutic inhibition of estrogen receptor-α and CDK4/6 expression, decipher the chemoprevention-signaling cascade in preclinical model of breast cancer
Suman Kumar Samanta a,b,*,1, Paramita Choudhury b,c,1, Raghuram Kandimalla b,d,e,1, Farrukh Aqil d,f, Disha N. Moholkar d,e, Ramesh C. Gupta d,e, Momita Das b, Bhaskarjyoti Gogoi g, Neelutpal Gogoi h, Partha Pratim Sarma b, Rajlakshmi Devi b,**, Narayan C. Talukdar
doi : 10.1016/j.jep.2023.117235
Volume 319, Part 2, 30 January 2024, 117235
Research progress on traditional Chinese medicine-induced apoptosis signaling pathways in ovarian cancer cells
Yu Wang a,1, Liangzhen Xie b, Fangyuan Liu b, Danni Ding a, Wei Wei a, Fengjuan Han
doi : 10.1016/j.jep.2023.117299
Volume 319, Part 2, 30 January 2024, 117299
A comprehensive review of the classical prescription Yiguan Jian: Phytochemistry, quality control, clinical applications, pharmacology, and safety profile
Changcheng Lu a,b,1, Siyuan Zhang a,b,1, Si San Lei a,b, Danni Wang a, Bo Peng a,b, Ruipeng Shi a,b, Cheong-Meng Chong a,**, Zhangfeng Zhong a,b,*, Yitao Wang
doi : 10.1016/j.jep.2023.117230
Volume 319, Part 2, 30 January 2024, 117230
Medicinal patterns of vines used in Chinese herbal medicine: a quantitative study
Yanlin Ding a,b,1, Dingping Zhao a,b,1, Tingye Wang a,b,1, Zhenyu Xu a,b, Yuxuan Fu a,b, Li Tao
doi : 10.1016/j.jep.2023.117184
Volume 319, Part 2, 30 January 2024, 117184
Herbal therapeutics for female infertility: A systematic review and meta-analysis
Ji-Yoon Hyun , Hyeon-Suk Jung , Ji-Yeun Park
doi : 10.1016/j.jep.2023.117258
Volume 319, Part 2, 30 January 2024, 117258
Mechanism of herb pair containing Astragali Radix and Spatholobi Caulis in the treatment of myelosuppression based on network pharmacology and experimental investigation
Fei Peng a,b, Wanying Hong a, Yingyu Wang a,b, Yunru Peng a,b,*, Zhijun Fang
doi : 10.1016/j.jep.2023.117178
Volume 319, Part 2, 30 January 2024, 117178
Pyrolae herba alleviates cognitive impairment via hippocampal TREM2 signaling modulating neuroinflammation and neurogenesis in lipopolysaccharide-treated mice
Yan Sun a,b,1, Hailou Zhang c,1, Ruiyu Liu a,b,c, Rumin Huang a,b, Xiangrui Zhang a,b, Shihan Zhou a,b, Lei Wu d, Boran Zhu a,b,**, Haoxin Wu
doi : 10.1016/j.jep.2023.117214
Volume 319, Part 2, 30 January 2024, 117214
Guben Xiezhuo Decoction inhibits M1 polarization through the Raf1/p-Elk1 signaling axis to attenuate renal interstitial fibrosis
Yue Liu a,b,1, Jingyi Wu a,b,1, Shuo Liang a, Jiawei Xu a, Minggang Wei c,***, Zhenfang Du a,**, Sheng Qiang
doi : 10.1016/j.jep.2023.117189
Volume 319, Part 2, 30 January 2024, 117189
SiJunZi decoction ameliorates bone quality and redox homeostasis and regulates advanced glycation end products/receptor for advanced glycation end products and WNT/β-catenin signaling pathways in diabetic mice
Xuan Dai a,1, Yage Liu a,1, Tianyuan Liu a, Yueyi Zhang a, Shan Wang a, Tianshu Xu a, Jiyuan Yin a, Hanfen Shi a, Zimengwei Ye a, Ruyuan Zhu a, Junfeng Gao b, Guangtong Dong c, Dandan Zhao a, Sihua Gao a, Xinxiang Wang b, Marc Prentki d, Dieter Br?mme e, Lili Wang f,**, Dongwei Zhang
doi : 10.1016/j.jep.2023.117167
Volume 319, Part 2, 30 January 2024, 117167
Mechanism difference of ginseng medicines with different natures on hyperthyroidism
Linlin Liu a, Xueying Han a, Guoshun Shan b,**, Li Fu c, Deqiang Dou
doi : 10.1016/j.jep.2023.117194
Volume 319, Part 2, 30 January 2024, 117194
Effect and mechanism of Qing Gan Zi Shen decoction on heart damage induced by obesity and hypertension
Shujie Zhang a,1, Zitian Liu a,1, Han Zhang a,1, Xiaonian Zhou a, Xiuming Wang a, Yan Chen a, Xiaofan Miao a, Yao Zhu a,*, Weimin Jiang
doi : 10.1016/j.jep.2023.117163
Volume 319, Part 2, 30 January 2024, 117163
In vitro and in vivo anti-inflammatory and antiophidic effects of the extract and fraction of Eugenia uniflora
Alessandra Daniele-Silva a,b, Adriana Marina e Silva Parente a,b, Sarah de Sousa Ferreira b, Diana Pontes da Silva b, Manoela Torres-Rˆego b,c, Felipe França Cavalcanti b,c, Magda Rhayanny Assunç?ao Ferreira a, Matheus de Freitas Fernandes-Pedrosa b, Luiz Alberto Lira Soares
doi : 10.1016/j.jep.2023.117223
Volume 319, Part 2, 30 January 2024, 117223
Phytochemical characterization, anti-diarrhoeal, analgesic, anti-inflammatory activities and toxicity profile of Ananas comosus (L.) Merr (pineapple) leaf in albino rats
Eziuche Amadike Ugbogu a,*, Happiness Okoro a, Okezie Emmanuel a, Ositadinma Chinyere Ugbogu b, Celestine Nwabu Ekweogu c, Miracle Uche a, Emmanuel Dike Dike a, Solomon Nnah Ijioma
doi : 10.1016/j.jep.2023.117224
Volume 319, Part 2, 30 January 2024, 117224
Stigmasterol and gastrodin, two major components of banxia-baizhu-tianma decoction, alleviated the excessive phlegm-dampness hypertension by reducing lipid accumulation
Honghua Zhang a,b, Yunting Sun c,**, Yuqing Zou a,b, Cheng Chen a,b, Shuling Wang
doi : 10.1016/j.jep.2023.117193
Volume 319, Part 2, 30 January 2024, 117193
The beneficial effect of Sanhuang ointment and its active constituents on experimental hemorrhoids in rats
Qian Yu a,1, Yu Zhao a,1, Xinyue Zhang a, Wenjie Li a, Hongyin Zhang a,b, Songlan Piao a, Guangzhe Li a,b,c,**, Mingming Yan
doi : 10.1016/j.jep.2023.117173
Volume 319, Part 2, 30 January 2024, 117173
TMT-based quantitative proteomics reveals the protective mechanism of tenuigenin after experimental intracerebral hemorrhage in mice
Peng Wang a,b,1, YiQing Shen a,b,1, Anatol Manaenko a,b, FangYu Liu a,b, WenSong Yang a,b, ZhongSong Xiao a,b, PeiZheng Li a,b, YuXin Ran a,b, RuoZhi Dang a,b, Yong He a,b, QingYuan Wu b,c, Peng Xie a,b,*, Qi Li
doi : 10.1016/j.jep.2023.117213
Volume 319, Part 2, 30 January 2024, 117213
Integrated analysis of metabolomic and transcriptomic profiling reveals the effect of Atractylodes oil on Spleen Yang Deficiency Syndrome in rats
Xin Zhan a,1, Yangxin Xiao a,1, Qipan Jian a, Yan Dong a, Chang Ke a, Zhongshi Zhou a,b, Yanju Liu a,b,**, Jiyuan Tu
doi : 10.1016/j.jep.2023.117205
Volume 319, Part 2, 30 January 2024, 117205
Black mulberry extract inhibits hepatic adipogenesis through AMPK/mTOR signaling pathway in T2DM mice
Yudi Yao a,1, Yang Chen b,1, Huijian Chen a, Xin Pan a, Xiaojun Li a, Wenqi Liu a, Yerlan Bahetjan a, Binan Lu c, Kejian Pang d, Xinzhou Yang a,*, Zongran Pang
doi : 10.1016/j.jep.2023.117216
Volume 319, Part 2, 30 January 2024, 117216
Xuanbai Chengqi Decoction alleviates acute lung injury by inhibiting NLRP3 inflammasome
Shun Wang a,b,1, Feifei Lin c,1, Chengxi Zhang a,b, Dan Gao a,b, Zhuocao Qi a,b, Suwan Wu a,b, Wantao Wang a,b, Xiaoqian Li a,b, Lingyun Pan d, Yanwu Xu e, Bo Tan f,**, Aidong Yang
doi : 10.1016/j.jep.2023.117227
Volume 319, Part 2, 30 January 2024, 117227
Di-Huang-Yin-Zi regulates P53/SLC7A11 signaling pathway to improve the mechanism of post-stroke depression
Zhou Yang a,1, Yongxia Jiang a,1, Yang Xiao b,1, Lihui Qian c, Yongqu Jiang a, Yue Hu b,d,**, Xiaoli Liu
doi : 10.1016/j.jep.2023.117226
Volume 319, Part 2, 30 January 2024, 117226
Fagopyrum tataricum (L.) Gaertn interacts with Gsk-3β/Nrf-2 signalling to protect neurotoxicity in a zebrafish model
Shubham Nilkanth Rahmatkar a,b, Anil Kumar Rana a,b, Rajneesh Kumar a,b, Damanpreet Singh
doi : 10.1016/j.jep.2023.117187
Volume 319, Part 2, 30 January 2024, 117187
Deciphering the antifungal mechanism and functional components of cinnamomum cassia essential oil against Candida albicans through integration of network-based metabolomics and pharmacology, the greedy algorithm, and molecular docking
Keru Gu a,1, Shengyi Feng b,1, Xinyue Zhang a, Yuanyuan Peng a, Peipei Sun a, Wenchi Liu a, Yi Wu a, Yun Yu a, Xijian Liu a, Xiaohui Liu a, Guoying Deng c, Jun Zheng b,***, Bo Li b,**, Linjing Zhao
doi : 10.1016/j.jep.2023.117156
Volume 319, Part 2, 30 January 2024, 117156
Anti-inflammatory, antioxidant and photoprotective activity of standardised Gaultheria procumbens L. leaf, stem, and fruit extracts in UVA-irradiated human dermal fibroblasts
Piotr Michel a,*, Halina Ma?gorzata ?Zbikowska b, Karolina Rudnicka c, Weronika Gonciarz c, Agnieszka Krupa c, Adrian Gajewski d, Paulina Macha?a b, Monika Anna Olszewska
doi : 10.1016/j.jep.2023.117219
Volume 319, Part 2, 30 January 2024, 117219
Intervention effect of Lycium barbarum polysaccharide on lead-induced kidney injury mice and its mechanism: A study based on the PI3K/Akt/mTOR signaling pathway
Wen Xie a,b, Hua-guo Chen a,b, Ru-hai Chen a,b, Chao Zhao a,b, Xiao-jian Gong a,b, Xin Zhou
doi : 10.1016/j.jep.2023.117197
Volume 319, Part 2, 30 January 2024, 117197
Yi-shen-hua-shi granules modulate immune and inflammatory damage via the ALG3/PPARγ/NF-κB pathway in the treatment of immunoglobulin a nephropathy
Rongjia Xu a,b,1, Jiajia Zhang a,b,1, Xingge Hu a,b, Penghao Xu a,b, Shiqi Huang a,b, Shiyan Cui a,b, Yuxin Guo a,b, Hongtao Yang a,b, Xiangmei Chen c, Chen Jiang
doi : 10.1016/j.jep.2023.117204
Volume 319, Part 2, 30 January 2024, 117204
Prunella vulgaris L. attenuates gut dysbiosis and endotoxin leakage against alcoholic liver disease
Pei-Li Rao a,b,1, Yun-Hui Shen a,1, Yi-Jie Song a,b, Yu Xu a,b,**, Hong-Xi Xu
doi : 10.1016/j.jep.2023.117237
Volume 319, Part 2, 30 January 2024, 117237
Quality evaluation of Angelica Sinensis Radix dispensing granules by integrating microvascular activity and chemical analysis
Wen-jie Li a,e,1, Yu-feng Cai a,1, Yi Ouyang b,1, Xian-yu Li a,d, Xiao-lu Shi a,d, Sheng-xuan Cao a, Ying Huang a,d,*,2, Hong-wei Wu b,**,2, Hong-jun Yang
doi : 10.1016/j.jep.2023.117236
Volume 319, Part 2, 30 January 2024, 117236
Chemical characterization, anti-struvite crystal, anti-inflammatory, analgesic, and antidepressant activities of Papaver rhoeas L. root and leaf extracts
Anouar Hmamou a,*, Mostafa El Khomsi b, El-Mehdi El-Assri a,c, Mohammed Kara d, Fatima Ezzahra El oumari e, Faiçal El Ouadrhiri a, Ahmed Bendaoud a, Ibtissame Elmansouri a,c, Noureddine Eloutassi a, Amal Lahkimi
doi : 10.1016/j.jep.2023.117208
Volume 319, Part 2, 30 January 2024, 117208
The anti-hepatocellular carcinoma effect of Aidi injection was related to the synergistic action of cantharidin, formononetin, and isofraxidin through BIRC5, FEN1, and EGFR
Shan Lu a, Jiaqi Huang a, Jingyuan Zhang a, Chao Wu a, Zhihong Huang a, Xiaoyu Tao a, Leiming You b, Antony Stalin c, Meilin Chen a, Jiaqi Li a, Yingying Tan a, Zhishan Wu a, Libo Geng d, Zhiqi Li a,e, Qiqi Fan a,e, Pengyun Liu a, Yifan Lin a, Chongjun Zhao a,e,**, Jiarui Wu
doi : 10.1016/j.jep.2023.117209
Volume 319, Part 2, 30 January 2024, 117209
Bioactive metabolites reveal the therapeutic consistency of epimedii folium from multi-plant sources for the treatment of kidney-yang deficiency
Xinguang Sun a,1, Yingfei Li b,1, Juan Li c,1, Haizhen Liang a,1, Jie Zhang a, Xiaojuan Chen a, Qi Li a, Xu Pang a, Qianzhi Ding a, Juan Song a, Baolin Guo d,**, Baiping Ma
doi : 10.1016/j.jep.2023.117215
Volume 319, Part 2, 30 January 2024, 117215
Calenduloside E ameliorates non-alcoholic fatty liver disease via modulating a pyroptosis-dependent pathway.
Yifei Le 1, Jianan Guo 1, Zhijun Liu , Jing Liu , Ying Liu , Hang Chen , Jiannan Qiu , Cui Wang , Xiaobing Dou **, Dezhao Lu
doi : 10.1016/j.jep.2023.117239
Volume 319, Part 2, 30 January 2024, 117239
Gancao Xiexin Decoction inhibits gastric carcinoma proliferation and migration by regulating the JAK2/STAT3 signalling pathway
Yating Yang b, Ling Yuan d, Fandi Meng a, Doudou Lu c, Mengying Che a, Xin Zhou b, Guoqing Chen d, Na Ning b, Yi Nan
doi : 10.1016/j.jep.2023.117241
Volume 319, Part 2, 30 January 2024, 117241
The regulatory effect of Angelicae Sinensis Radix on neuroendocrine-immune network and sphingolipid metabolism in CUMS-induced model of depression
Wenxia Gong a,b,c,*, Jinlong Chen a, Shaohua Xu a, Yuanji Li d, Yuzhi Zhou a,b,c, Xuemei Qin
doi : 10.1016/j.jep.2023.117217
Volume 319, Part 2, 30 January 2024, 117217
Xinmaikang (XMK) tablets alleviate atherosclerosis by regulating the SREBP2-mediated NLRP3/ASC/Caspase-1 signaling pathway
Chijun Hou a, Xinyue Jiang b, Wenjuan Sheng a, Yuling Zhang b, Qianbei Lin b, Shihan Hong b, Jiale Zhao b, Ting Wang a, Xiaohan Ye
doi : 10.1016/j.jep.2023.117240
Volume 319, Part 2, 30 January 2024, 117240
Ethnopharmacological analysis based on Thai traditional medicine theory and anti-inflammatory activity of Sa-Tri-Lhung-Klod remedy as a post-partum anti-inflammatory drug
Janjira Inprasit a, Arunporn Itharat b,c,*, Srisopa Ruangnoo b, Krittiya Thisayakorn d,**, Kanmanee Sukkasem b, Nuntika Prommee b, Wicheian Khoenok d, Kanjana Sriyam d, Darunee Pahusee d, Neal M. Davies e,
doi : 10.1016/j.jep.2023.117207
Volume 319, Part 2, 30 January 2024, 117207
Multi-target meridians classification based on the topological structure of anti-cancer phytochemicals using deep learning
Sheng Zhang a, Xianwei Zhang a, Jiayin Du b, Wei Wang c,*, Xitian Pi
doi : 10.1016/j.jep.2023.117244
Volume 319, Part 2, 30 January 2024, 117244
