Diabetes, Obesity and Metabolism




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Role of the tripartite motif-containing (TRIM) family of proteins in insulin resistance and related disorders

Jianrong Chen MD 1,2,3 | Xianjie Feng MB 4 | Xu Zhou MD 4 | Yong Li PhD

doi : 10.1111/dom.15294

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Pancreatic islet cell plasticity: Pathogenic or therapeutically exploitable?

Neil Tanday PhD 1,2 | Andrei I. Tarasov PhD 1 | R. Charlotte Moffett PhD 1 | Peter R. Flatt PhD 1 | Nigel Irwin PhD

doi : 10.1111/dom.15300

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Human placenta-derived mesenchymal stem cells ameliorate diabetic kidney disease by modulating the T helper 17 cell/ regulatory T-cell balance through the programmed death 1 / programmed death-ligand 1 pathway

Jiao Wang MD 1,2,3 | Honghong Liu MS 1 | Guanru Yue MS 1,4 | Yuanyuan Deng MS 1 | Wei Cai MD 4 | Jixiong Xu MD

doi : 10.1111/dom.15282

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Intermittently scanned continuous glucose monitoring and hypoglycaemia awareness in drivers with diabetes: Insights from the Association of British Clinical Diabetologists Nationwide audit

Charlotte Mark-Wagstaff MBChB 1 | Harshal Deshmukh MBBS 1,2 | Emma G. Wilmot MBChB 3,4 | Neil Walker MBBS 5 | Dennis Barnes MBBS 6 | Vernon Parfitt MBChB 7 | Simon Saunders MBChB 8 | Rob Gregory MBBS 9 | Pratik Choudhary MBBS 9 | Jane Patmore MBBS 1 | Chris Walton MBBS 1 | Robert E. J. Ryder MBChB 10 | Thozhukat Sathyapalan MBBS

doi : 10.1111/dom.15283

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Albuminuria-lowering effect of adding semaglutide on top of empagliflozin in individuals with type 2 diabetes: A randomized and placebo-controlled study

Suvanjaa Sivalingam MD 1 | Victor Soendergaard Wasehuus MD 1 | Viktor Rotbain Curovic MD 1 | Martin B?k Blond PhD 1 | Tine W. Hansen PhD 1 | Frederik Persson DMSc 1 | Peter Rossing DMSc

doi : 10.1111/dom.15287

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Abolishing β-arrestin recruitment is necessary for the full metabolic benefits of G protein-biased glucagon-like peptide-1 receptor agonists

Charlotte E. Hinds PhD 1 | Ellie Peace BSc 1 | Shiqian Chen MRes 1 | Iona Davies MRes 1 | Liliane El Eid MRes 2 | Alejandra Tomas PhD 2 | Tricia Tan MD 1 | James Minnion PhD 1 | Ben Jones MD 1 | Stephen R. Bloom MD

doi : 10.1111/dom.15288

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Comparison of Control-IQ and open-source AndroidAPS automated insulin delivery systems in adults with type 1 diabetes: The CODIAC study

Quoc Dat Do MD 1 | Aneta H?skov? MSc 1 | Lucie Radovnick? MD 2,3 | Judita Kone?cn? MSc 1 | Eva Horov? MD 1 | Christopher G. Parkin MS 4 | George Grunberger MD 5 | Martin Pr?zn? MD 1 | Jan ?Soupal MD

doi : 10.1111/dom.15289

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Global burden of diabetes mellitus from 1990 to 2019 attributable to dietary factors: An analysis of the Global Burden of Disease Study 2019

Ting Hong MD 1 | Fangfang Sun MD 1 | Qiwei Wang MD 1 | Xufeng Chen MD 2 | Kun Han PhD

doi : 10.1111/dom.15290

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Differential effect of interventions in patients with prediabetes stratified by a machine learning-based diabetes progression prediction model

Xiantong Zou MD 1 | Yingying Luo MD 1 | Qi Huang MD 1 | Zhanxing Zhu PhD 2,3,4 | Yufeng Li MD 5 | Xiuying Zhang MD 1 | Xianghai Zhou MD 1 | Linong Ji MD

doi : 10.1111/dom.15291

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Risk of thyroid cancer associated with glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes: A population-based cohort study

Sungho Bea PharmD 1 | Heejun Son MD 2 | Jae Hyun Bae MD 3 | Sun Wook Cho MD 2,4 | Ju-Young Shin PhD 1,5,6 | Young Min Cho MD

doi : 10.1111/dom.15292

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Telehealth use and its impact on clinical outcomes in patients with type 2 diabetes during the COVID-19 pandemic

Yixue Shao PhD 1 | Lizheng Shi PhD 1 | Elizabeth Nauman PhD 2 | Eboni Price-Haywood MD 3 | Charles Stoecker PhD

doi : 10.1111/dom.15293

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Glycaemic control, body weight, and safety of tirzepatide versus dulaglutide by baseline glycated haemoglobin level in Japanese patients with type 2 diabetes: A subgroup analysis of the SURPASS J-mono study

Takeshi Osonoi MD 1 | Tomonori Oura MSc 2 | Tetsuaki Hirase MD

doi : 10.1111/dom.15296

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Multi-tissue transcriptome-wide association study reveals susceptibility genes and drug targets for insulin resistance-relevant phenotypes

Yuan-Yuan Duan BS 1 | Xin Ke PhD 1 | Hao Wu BS 1 | Shi Yao PhD 1 | Wei Shi MSc 1 | Ji-Zhou Han BS 1 | Ren-Jie Zhu BS 1 | Jia-Hao Wang BS 1 | Ying-Ying Jia BS 1 | Tie-Lin Yang PhD 1 | Meng Li MD 2 | Yan Guo PhD

doi : 10.1111/dom.15298

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Societal health and economic burden of cardiovascular diseases in the population with type 2 diabetes in Qatar. A 10-year forecasting model

Dina Abushanab MSc 1 | Daoud Al-Badriyeh PhD 2 | Clara Marquina PhD 1 | Danny Liew PhD 3 | Manal Al-Zaidan PharmD 4 | Mohammed Ghaith Al-Kuwari MD 5 | Jazeel Abdulmajeed PhD 5 | Zanfina Ademi PhD

doi : 10.1111/dom.15299

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The impact of type 2 diabetes and glycaemic control on mortality and clinical outcomes in hospitalized patients with COVID-19 in the capital region of Denmark

Vivian Kliim-Hansen MD 1 | Karl S. Johansson MD 2 | L?rke S. Gasbjerg PhD 1,3 | Espen Jimenez-Solem PhD 2,4,5,6 | Tonny S. Petersen MD 2,5 | Martin E. Nyeland PhD 2,4 | Matilde Winther-Jensen PhD 7 | Mikkel Z?llner Ankarfeldt PhD 6 | Miriam G. Pedersen PhD 1 | Anne-Marie Ellegaard PhD 1 | Filip K. Knop MD 1,3,4,8 | Mikkel B. Christensen MD

doi : 10.1111/dom.15302

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Construction and validation of a nomogram for predicting diabetes remission at 3 months after bariatric surgery in patients with obesity combined with type 2 diabetes mellitus

Kaisheng Yuan MD 1,2 | Bing Wu MD 1,2 | Ruiqi Zeng MM 3 | Fuqing Zhou MM 1,2 | Ruixiang Hu MD 1,2 | Cunchuan Wang MD

doi : 10.1111/dom.15303

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Repeated detection of non-alcoholic fatty liver disease increases the incidence risk of type 2 diabetes in young adults

Jin Hwa Kim MD 1 | Young Sang Lyu MD 1 | Mee Kyoung Kim MD 2 | Sang Yong Kim MD 1 | Ki-Hyun Baek MD 2 | Ki-Ho Song MD 2 | Kyungdo Han PHD 3 | Hyuk-Sang Kwon MD

doi : 10.1111/dom.15304

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Efficacy of finerenone in patients with type 2 diabetes, chronic kidney disease and altered markers of liver steatosis and fibrosis: A FIDELITY subgroup analysis

Nikolaos Perakakis MD 1,2,3 | Stefan R. Bornstein MD 1,2,3,4 | Andreas L. Birkenfeld MD 3,4,5,6 | Andreas Linkermann MD 1,7 | Münevver Demir MD 8 | Stefan D. Anker MD 9,10 | Gerasimos Filippatos MD 11 | Bertram Pitt MD 12 | Peter Rossing MD 13,14 | Luis M. Ruilope MD 15,16,17 | Peter Kolkhof PhD 18 | Robert Lawatscheck MD 19 | Charlie Scott MSc 20 | George L. Bakris MD 21 | FIDELIO-DKD and FIGARO-DKD investigators

doi : 10.1111/dom.15305

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Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial

Signe Foghsgaard MD 1,2,3 | Louise Vedtofte MSc 1,3 | Emilie S. Andersen MD 1,3 | Emilie Bahne MD 1,3 | Camilla Andreasen MD 1,3 | Anne L. S?rensen MSc 4 | Julie L. Forman MSc 4 | Elisabeth R. Mathiesen MD 5,6 | Jens A. Svare MD 2 | Tine D. Clausen MD 7 | Peter Damm MD 5,7 | Jens J. Holst MD 8,9 | Filip K. Knop MD 1,3,5,9 | Tina Vilsb?ll MD

doi : 10.1111/dom.15306

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Ultra rapid lispro (Lyumjev®) shortens time to recovery from hyperglycaemia compared to Humalog® in individuals with type 1 diabetes on continuous subcutaneous insulin infusion

Jennifer Leohr PhD 1 | Mary Anne Dellva MS 1 | Elizabeth LaBell BS 1 | David E. Coutant PhD 1 | Jorge Arrubla MD 2 | Leona Plum-M?rschel MD 2,3 | Eric Zijlstra PhD 2 | Tsuyoshi Fukuda PhD 1 | Thomas Hardy MD

doi : 10.1111/dom.15307

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Types of diabetes during pregnancy and risk of depression and anxiety in offspring from childhood to young adulthood

Anny H. Xiang PhD 1 | Jane C. Lin MS 1 | Ting Chow MPH 1 | Mayra P. Martinez MPH 1 | Sonya Negriff PhD 1 | Kathleen A. Page MD 2 | Rob McConnell MD 3 | Sarah A. Carter PhD

doi : 10.1111/dom.15308

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Proportion of participants with type 2 diabetes achieving a metabolic composite endpoint with once-weekly semaglutide treatment versus comparators: Post hoc pooled analysis from SUSTAIN 1-5, 7-10 and SUSTAIN China

Linong Ji MD 1 | A. J. Ahmann MD 2 | B. Ahrén MD 3 | M. S. Capehorn BMedSciMBChB 4 | P. Hu MD 5 | I. Lingvay MD 6 | W. Liu MS 5 | H. W. Rodbard MD 7 | Z. Shen MSc 5 | C. Sorli MD

doi : 10.1111/dom.15309

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The effect of metformin on urate metabolism: Findings from observational and Mendelian randomization analyses

Huajie Dai MD 1,2 | Tianzhichao Hou MD 1,2 | Qi Wang MD 1,2 | Zheng Zhu MD 1,2 | Yijie Zhu MD 1,2 | Zhiyun Zhao PhD 1,2 | Mian Li PhD 1,2 | Yu Xu PhD 1,2 | Jieli Lu PhD 1,2 | Tiange Wang PhD 1,2 | Guang Ning PhD 1,2 | Weiqing Wang PhD 1,2 | Yufang Bi PhD 1,2 | Jie Zheng PhD 1,2,3 | Min Xu PhD

doi : 10.1111/dom.15310

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Bone marrow metabolism is affected by body weight and response to exercise training varies according to anatomical location

Ronja Ojala MD 1 | Jaakko Hentil? PhD 1 | Martin S. Lietzén MD 1 | Milja Arponen MSc 2 | Marja A. Heiskanen PhD 1,3,4 | Sanna M. Honkala PhD 1 | Heidi Virtanen MB 1 | Kalle Koskensalo MSc 5 | Riikka Lautam?ki MD 6 | Eliisa L?yttyniemi PhD 7 | Riitta Parkkola MD 8,9 | Olli J. Heinonen MD 10 | Tarja Malm PhD 11 | Leo Lahti PhD 12 | Juha Rinne MD 1,13 | Olli Eskola PhD 14 | Johan Rajander MSc 15 | Kirsi H. Pietil?inen MD 16,17 | Jaakko Kaprio MD 18 | Kaisa K. Ivaska PhD 2 | Jarna C. Hannukainen PhD

doi : 10.1111/dom.15311

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Effect of tirzepatide on glycaemic control and weight loss compared with other glucagon-like peptide-1 receptor agonists in Japanese patients with type 2 diabetes mellitus

Shunichiro Tsukamoto MD 1 | Shohei Tanaka MD 1 | Takayuki Yamada PhD 1,2 | Kazushi Uneda PhD 1,3 | Kengo Azushima PhD 1 | Sho Kinguchi PhD 1 | Hiromichi Wakui PhD 1 | Kouichi Tamura PhD

doi : 10.1111/dom.15312

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Incremental burden on health-related quality of life, health service utilization and direct medical expenditures associated with cognitive impairment among non-institutionalized people with diabetes aged 65 years and older

Dawei Guan MD 1 | Motomori O. Lewis BS 1 | Piaopiao Li MS 1 | Yichen Zhang PhD 2 | Ping Zhang PhD 3 | Shichao Tang PhD 3 | Joshua Brown PharmD 1 | Jingchuan Guo MD 1 | Yongkang Zhang PhD 4 | Hui Shao MD

doi : 10.1111/dom.15313

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The relationship between glycated haemoglobin and blood glucose-lowering treatment trajectories in type 2 diabetes: The Fremantle Diabetes Study Phase II

Timothy M. E. Davis FRACP | Wendy Davis PhD

doi : 10.1111/dom.15314

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Time trends towards earlier puberty in boys and girls with type 1 diabetes: Insights from the German Diabetes Prospective Follow-up (DPV) registry, 2000 to 2021

Bettina Gohlke MD 1 | Felix Reschke MD 2 | Stefanie Lanzinger PhD 3,4 | Claudia Boettcher MD 5 | Gitta Gemulla MD 6 | Susanne Thiele-Schmitz MD 7 | Désirée Dunstheimer MD 8 | Louise van den Boom MD 9 | Joachim Woelfle MD 10 | Reinhard W. Holl MD

doi : 10.1111/dom.15315

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Associations of bolus insulin injection frequency and smart pen engagement with glycaemic control in people living with type 1 diabetes

Jarl Hellman MD 1 | Niels V?ver Hartvig PhD 2 | Anne Kaas MD 2 | Jonas Bech M?ller PhD 2 | Mads Reinholdt S?rensen PhD 2 | Johan Jendle MD

doi : 10.1111/dom.15316

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Ultra-rapid lispro improved postprandial glucose control compared to insulin lispro in predominantly Chinese patients with type 1 diabetes: A prospective, randomized, double-blind phase 3 study

Jianhua Ma MD 1 | Xiang Yan MD 2 | Qiong Feng MD 2 | Wei Liu MD 2 | Federico Pérez Manghi MD 3 | Pedro Garc?a-Hern?ndez MD 4 | Guixia Wang MD 5 | Jianwei Xu MD 6 | Yuan Yuan PhD 6 | Zhiguang Zhou MD

doi : 10.1111/dom.15317

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Tirzepatide reduces the predicted risk of atherosclerotic cardiovascular disease and improves cardiometabolic risk factors in adults with obesity or overweight: SURMOUNT-1 post hoc analysis

Emily R. Hankosky PhD 1 | Hui Wang PhD 2 | Lisa M. Neff MD 1 | Hong Kan PhD 1 | Fangyu Wang MS 1 | Nadia N. Ahmad MD 1 | Ryan Griffin PhD 1 | Adam Stefanski MD 1 | W. Timothy Garvey MD

doi : 10.1111/dom.15318

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Sustained metabolic benefits of �TRTX-Ac1, a tarantula venom-derived peptide, when administered together with exenatide in high-fat fed mice

Aimee Coulter-Parkhill PhD | Neil Tanday PhD | Diego Cobice PhD | Christopher M. McLaughlin PhD | Stephen McClean PhD | Victor A. Gault PhD | Nigel Irwin PhD

doi : 10.1111/dom.15319

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Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high-fat diet-fed mouse model

K?lm?n Bodis MD 1,2,3 | Saida Breuer PhD 3,4 | Assja Crepzia-Pevzner MSc 3,4 | Oana-Patricia Zaharia MD 1,2,3 | Martin Sch?n PhD 2,3 | Nina Saatmann MSc 2,3 | Delsi Altenhofen PhD 3,4 | Christian Springer PhD 3,4 | Julia Szendroedi MD 2,5,6 | Robert Wagner MD 1,2,3 | Hadi Al-Hasani PhD 3,4 | Michael Roden MD 1,2,3 | Dominik Pesta PhD 7,8,9 | Alexandra Chadt PhD 3,4 | for the GDS Group

doi : 10.1111/dom.15322

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Distinct effects of type 2 diabetes and obesity on cardiopulmonary performance

Lorenzo Nesti MD 1,2 | Nicola Riccardo Pugliese MD 2 | Lorenza Santoni MD 1 | Silvia Armenia PhD 2 | Martina Chiriac? MD 1 | Luca Sacchetta MD 1 | Nicol? De Biase MD 2 | Lavinia Del Punta MD 2 | Stefano Masi MD 2 | Domenico Tric? MD 1 | Andrea Natali MD

doi : 10.1111/dom.15324

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Effects of continuous glucose monitoring on glycaemic control in type 2 diabetes: A systematic review and network meta-analysis of randomized controlled trials

Jiaping Lu MD 1 | Zhen Ying PhD 2 | Ping Wang MD 1 | Minjie Fu PhD 3 | Chenyu Han MD 1 | Min Zhang PhD

doi : 10.1111/dom.15328

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Sex-specific causality of MRI-derived body compositions on glycaemic traits: Mendelian randomization and observational study

Yijie Zhu MD 1,2 | Qi Wang MD 1,2 | Huajie Dai MD 1,2 | Tianzhichao Hou MD 1,2 | Tiange Wang PhD 1,2 | Zhiyun Zhao PhD 1,2 | Mian Li PhD 1,2 | Wei Miao BD 1,2 | Jian Yang BD 1,2 | Jieli Lu PhD 1,2 | Yu Xu PhD 1,2 | Yuhong Chen PhD 1,2 | Guang Ning PhD 1,2 | Jie Zheng PhD 1,2,3 | Yufang Bi PhD 1,2 | Min Xu PhD 1,2 | Weiqing Wang PhD

doi : 10.1111/dom.15326

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The effect of empagliflozin and fenofibrate therapies, alone and in combination, on the serum urate concentration in hyperuricaemic type 2 diabetes

Timothy M. E. Davis FRACP 1 | Sharon Maxwell BSc(Nurs) 1 | Cathy Chan MPH 1 | Helen I. Keen FRACP 2 | Wendy A. Davis PhD

doi : 10.1111/dom.15295

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The glycaemic roller coaster phenomenon in type 1 diabetes

Mia Christensen MD 1 | Esben Lerkevang Grove Laugesen MD 1,2 | Bo M. Bibby MSc 3 | Klavs W. Hansen MD

doi : 10.1111/dom.15297

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Is composite cardiovascular death or hospitalization for heart failure a valid surrogate for mortality in patients treated with sodium-glucose cotransporter 2 inhibitors? A correlation meta-analysis

Alhassane Diallo MD 1 | Miguel Carlos-Bolumbu MD 2 | Florence Galtier MD

doi : 10.1111/dom.15320

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Impact on glycated haemoglobin and body weight changes after stopping tirzepatide for 4 weeks in the SURPASS-1 monotherapy trial

Julio Rosenstock MD 1 | Clare J. Lee MD 2 | Laura Fern?ndez Lando MD 2 | Minzhi Liu PhD 3 | Chrisanthi A. Karanikas MS 2 | Vivian T. Thieu PhD 2

doi : 10.1111/dom.15325

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Breaking a feedback loop: A reassessment of an investigator initiated OS-AID study

doi : 10.1111/dom.15301

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Letter of reply to ‘Breaking a feedback loop: A reassessment of an investigator-initiated OS-AID study’ by Braune et al.

doi : 10.1111/dom.15323

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