New England Journal of Medicine




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Deciding for Patients Who Have Lost Decision-Making Capacity — Finding Common Ground in Medical Ethics

Bernard Lo, M.D.

doi : 10.1056/NEJMp2308484

Vol. 389 No. 25

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Silencing the FDA’s Voice — Drug Information on Trial

Tina Watson, B.A., and Christopher Robertson, J.D., Ph.D.

doi : 10.1056/NEJMp2311006

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Hidden Behind Bars — The Public Health Implications of Incompetency to Stand Trial

Nathaniel P. Morris, M.D., and Jacob M. Izenberg, M.D.

doi : 10.1056/NEJMp2308861

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A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina

Christopher A. Rajkumar, M.B., B.S., Michael J. Foley, M.B., B.S., Fiyyaz Ahmed-Jushuf, M.B., B.S., Alexandra N. Nowbar, Ph.D., Florentina A. Simader, M.D., John R. Davies, Ph.D., Peter D. O’Kane, M.D., Peter Haworth, M.B., B.S., Helen Routledge, M.D., Tushar Kotecha, Ph.D., Reto Gamma, M.D., Gerald Clesham, Ph.D., Rupert Williams, Ph.D., Jehangir Din, M.D., Sukhjinder S. Nijjer, Ph.D., Nick Curzen, Ph.D., Neil Ruparelia, Ph.D., Manas Sinha, M.D., Jason N. Dungu, Ph.D., Sashiananthan Ganesananthan, M.B., B.S., Ramzi Khamis, Ph.D., Lal Mughal, M.B., B.S., Tim Kinnaird, M.D., Ricardo Petraco, Ph.D., James C. Spratt, M.D., Sayan Sen, Ph.D., Joban Sehmi, Ph.D., David J. Collier, Ph.D., Afzal Sohaib, Ph.D., Thomas R. Keeble, M.D., Graham D. Cole, Ph.D., James P. Howard, Ph.D., Darrel P. Francis, Ph.D., Matthew J. Shun-Shin, Ph.D., and Rasha K. Al-Lamee, Ph.D. for the ORBITA-2 Investigators*

doi : 10.1056/NEJMoa2310610

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Doxycycline Prophylaxis to Prevent Sexually Transmitted Infections in Women

Jenell Stewart, D.O., M.P.H., Kevin Oware, M.A., Deborah Donnell, Ph.D., Lauren R. Violette, M.P.H., Josephine Odoyo, R.N., M.P.H., Olusegun O. Soge, Ph.D., Caitlin W. Scoville, M.P.H., Victor Omollo, M.B., Ch.B., M.P.H., Felix O. Mogaka, M.B., Ch.B., Fredericka A. Sesay, M.B., Ch.B., M.P.H., R. Scott McClelland, M.D., M.P.H., Matthew Spinelli, M.D., M.P.H., Monica Gandhi, M.D., M.P.H., Elizabeth A. Bukusi, M.B., Ch.B., M.Med., M.P.H., Ph.D., and Jared M. Baeten, M.D., Ph.D. for the dPEP Kenya Study Team*

doi : 10.1056/NEJMoa2304007

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Simvastatin in Critically Ill Patients with Covid-19

doi : 10.1056/NEJMoa2309995

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Locally Acquired Melioidosis Linked to Environment — Mississippi, 2020–2023

Julia K. Petras, M.S.P.H., B.S.N., R.N., Mindy G. Elrod, B.A., Maureen C. Ty, Ph.D., Patrick Dawson, Ph.D., Kevin O’Laughlin, M.D., Jay E. Gee, Ph.D., Jennifer Hanson, R.N., Carla Boutwell, B.S.N., R.N., Gail Ainsworth, B.S.N., R.N., Cari A. Beesley, M.S., Elke Saile, Ph.D., Rebekah Tiller, M.P.H., Christopher A. Gulvik, Ph.D., Daphne Ware, Ph.D., Theresa Sokol, M.P.H., Gary Balsamo, D.V.M., Kathryn Taylor, M.D., Johanna S. Salzer, D.V.M., Ph.D., William A. Bower, M.D., Zachary P. Weiner, Ph.D., María E. Negrón, D.V.M., Ph.D., Alex R. Hoffmaster, Ph.D., and Paul Byers, M.D.

doi : 10.1056/NEJMoa2306448

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Eye Infections

Marlene L. Durand, M.D., Miriam B. Barshak, M.D., and Lucia Sobrin, M.D.

doi : 10.1056/NEJMra2216081

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Medial Branch Blocks and Radiofrequency Ablation for Low Back Pain from Facet Joints

David Hao, M.D., R. Jason Yong, M.D., Steven P. Cohen, M.D., and Milan P. Stojanovic, M.D.

doi : 10.1056/NEJMvcm2211108

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Thyroid Dermopathy in Graves’ Disease

Durairaj Arjunan, M.D., and Sanjay K. Bhadada, M.D., D.M.

doi : 10.1056/NEJMicm2303450

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Pericardial Decompression Syndrome

Nikkan Das, M.D., and Brian Feingold, M.D.

doi : 10.1056/NEJMicm2301048

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Case 39-2023: A 43-Year-Old Woman with Chronic Diarrhea, Hair Loss, and Nail and Skin Changes

Jimmy C.T. Lai, M.B., Ch.B., W.K. Claudia Wu, M.B., B.S., W.S. Agnes Chan, M.B., B.S., Louis H.S. Lau, M.B., Ch.B., and Howard H.W. Leung, M.B., Ch.B.

doi : 10.1056/NEJMcpc2301032

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Changing the Orbit around Percutaneous Coronary Intervention for Stable Angina

Harvey D. White, D.Sc.

doi : 10.1056/NEJMe2312633

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Doxycycline Postexposure Prophylaxis for STIs in Women — Uncertain Benefit, Urgent Need

Jeanne Marrazzo, M.D.

doi : 10.1056/NEJMe2311948

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Balancing Act — Probability, Precision, and the Future of Critical Care Trials in ARDS

Ari Moskowitz, M.D., M.P.H., and Michelle N. Gong, M.D., M.S.(Epidem.)

doi : 10.1056/NEJMe2312635

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Fundamentals of Medical Ethics — A New Perspective Series

Bernard Lo, M.D., Debra Malina, Ph.D., Genevra Pittman, M.P.H., and Stephen Morrissey, Ph.D.

doi : 10.1056/NEJMe2308472

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Methemoglobinemia Outbreak in a Neonatal ICU and Maternity Ward

doi : 10.1056/NEJMc2308125

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Semaglutide and Heart Failure with Preserved Ejection Fraction and Obesity

doi : 10.1056/NEJMc2312296

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Modifiable Risk Factors and Cardiovascular Outcomes

doi : 10.1056/NEJMc2312596

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Where Medical Statistics Meets Artificial Intelligence

doi : 10.1056/NEJMc2312332

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Severe Immune-Related Enteritis after In Utero Exposure to Pembrolizumab

doi : 10.1056/NEJMx230011

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Liver Transplantation for Mahvash Disease, an Inborn Error of Metabolism

doi : 10.1056/NEJMx230012

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