Journal of the European Academy of Dermatology and Venereology




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Issue Information

doi : 10.1111/jdv.16654

Volume 35, Issue 6 p. 1235-1240

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Editor’s picks

doi : 10.1111/jdv.17305

Volume 35, Issue 6 p. 1241-1241

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Scientific Publishing: How to select the best articles – a word about transparency

J. Ring

doi : 10.1111/jdv.17300

Volume 35, Issue 6 p. 1242-1243

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Commentary to Shetty A, Janda M, Fry K et al. Clinical utility of skin cancer and melanoma risk scores for population screening: TRoPICS study

K. Peris

doi : 10.1111/jdv.17267

Volume 35, Issue 6 p. 1244-1245

Skin cancers including melanoma, basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) represent a major disease burden and health care expenditure, especially in white population.

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Lentiginous melanoma – should we change the paradigm?

P. Pietkiewicz

doi : 10.1111/jdv.17291

Volume 35, Issue 6 p. 1246-1247

Lentigo maligna (LM) was initially regarded to have an infectious origin. It was described by Hutchinson (1890) and later named Hutchinson's melanotic freckle type. Almost two decades later, Dubreuilh (1912) defined it as melanosis circumscripta praecancerosa, a premalignant condition that may give rise to melanoma.

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Pioneers in Dermatology and Venereology: an interview with Professor Eva-Bettina Br?cker

E.B. Br?cker

doi : 10.1111/jdv.17292

Volume 35, Issue 6 p. 1248-1250

no abstract

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S2k guidelines (consensus statement) for diagnosis and therapy of dermatitis herpetiformis initiated by the European Academy of Dermatology and Venereology (EADV)

A. G?r?g, E. Antiga, M. Caproni, G. Cianchini, D. De, M. Dmochowski, J. Dolinsek, K. Drenovska, C. Feliciani, K. Hervonen, I. Lakos Jukic, ?. Kiny?, T. Koltai, I. Korponay-Szab?, A.V. Marzano, A. Patsatsi, C. Rose, T. Salmi, E. Schmidt, J. Setterfield, M. Shahid, C. Sitaru, S. Uzun, F. Valitutti, S. Vassileva, S. Yayli, M. S?rdy

doi : 10.1111/jdv.17183

Volume 35, Issue 6 p. 1251-1277

Dermatitis herpetiformis (DH) is a chronic, pruritic, gluten-induced skin disorder characterized by subepidermal granular IgA deposition and a variable degree of enteropathy identical to that seen in coeliac disease. So far, there has been no European consensus about the management of DH.

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Improved protection of outdoor workers from solar ultraviolet radiation: position statement

S.M. John, C. Garbe, L.E. French, J. Takala, W. Yared, A. Cardone, R. Gehring, A. Spahn, A. Stratigos

doi : 10.1111/jdv.17011

Volume 35, Issue 6 p. 1278-1284

The vast majority of non-melanoma skin cancer (NMSC) is attributable to excessive exposure to ultraviolet radiation (UVR). Outdoor workers are exposed to an UVR dose at least 2 to 3 times higher than indoor workers and often to daily UVR doses 5 times above internationally recommended limits.

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Incidence of occupational contact dermatitis in healthcare workers: a systematic review

F. Larese Filon, M. Pesce, M.S. Paulo, T. Loney, A. Modenese, S.M. John, S. Kezic, J. Macan

doi : 10.1111/jdv.17096

Volume 35, Issue 6 p. 1285-1289

Healthcare workers (HCWs) can be considered at an increased risk of developing occupational contact dermatitis (OCD) due to repetitive hand washing with soaps and disinfectants and extended use of gloves for many hours during the day.

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Desmoplastic melanoma: a review of its pathology and clinical behaviour, and of management recommendations in published guidelines

T.M. Hughes, G.J. Williams, D.E. Gyorki, J.W. Kelly, J.R. Stretch, A.H.R. Varey, A.M. Hong, R.A. Scolyer, J.F. Thompson

doi : 10.1111/jdv.17154

Volume 35, Issue 6 p. 1290-1298

Desmoplastic melanomas are uncommon. Their behaviour differs from that of other melanoma subtypes; therefore, management guidelines for non-desmoplastic melanomas may not be applicable.

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Therapeutic management in paediatric alopecia areata: A systematic review

A. Wa?kiel-Burnat, M. Ko?odziejak, M. Sikora, A. Stochmal, A. Rakowska, M. Olszewska, L. Rudnicka

doi : 10.1111/jdv.17187

Volume 35, Issue 6 p. 1299-1308

Alopecia areata is the third most common cause of dermatology consultations in children but the treatment of paediatric alopecia areata remains challenging. A systematic review of the literature about the treatment of alopecia areata in children (?18 years old) was performed on 11 May 2020 by searching the PubMed, Scopus and EBSCO databases.

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Lesion-directed screening to optimize skin cancer detection in dermatology practice: an observational study

S. Mylle, E. Verhaeghe, L. Van Coile, B. Van de Maele, I. Hoorens, L. Brochez

doi : 10.1111/jdv.17129

Volume 35, Issue 6 p. 1309-1314

Early detection of skin cancer is still a major challenge in dermatology practice today. While surveillance programs are offered to high-risk patients, systematic total-body examination (TBE) in the general population is not cost-effective. In the past, we demonstrated that a lesion-directed screening (LDS) in the general population delivered similar detection rates to TBE and was less time-consuming.

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Lentiginous melanoma (lentigo maligna and lentigo maligna melanoma) in Australia: clinicopathological characteristics, management and recurrence rates after 10-year follow-up at a tertiary centre

H. Collgros, E. Rodriguez-Lomba, A. Regio Pereira, S.N. Lo, R.A. Scolyer, P. Guitera

doi : 10.1111/jdv.17135

Volume 35, Issue 6 p. 1315-1322

Lentiginous melanoma or lentigo maligna is a slow-growing type of melanoma frequently arising in sun-damaged skin and often first diagnosed in the elderly. Few studies report long-term follow-up.

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Three-dimensional histology vs. serial section histology in the treatment of primary basal cell carcinoma: a randomized, prospective, blinded study of 569 tumours

L. Kofler, H. Breuninger, R.H. Schreiber, M. Eichner, H.-M. H?fner, S.M. Schnabl

doi : 10.1111/jdv.17155

Volume 35, Issue 6 p. 1323-1330

For basal cell carcinoma (BCC), only few controlled data have been published so far, which directly compare micrographically controlled surgery with conventional serial section histology. In addition to Mohs surgery, which uses cryostat sections, also three-dimensional histology (3D-histology), based on paraffin sections, is available to ensure complete control of the margins and basic sections.

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Rapid and sustained control of itch and reduction in Th2 bias by dupilumab in a patient with Sézary syndrome

O. Steck, N.L. Bertschi, F. Luther, J. van den Berg, D.J. Winkel, A. Holbro, C. Schlapbach

doi : 10.1111/jdv.17001

Volume 35, Issue 6 p. 1331-1337

Sézary syndrome is a leukaemic variant of cutaneous T-cell lymphoma with poor prognosis. With the exception of stem cell transplantation, current treatments for SS are not curative. Rather, they aim at reducing disease burden and improving quality of life. Yet, pruritus – the major cause for impaired quality of life in these patients – is notoriously difficult to treat. Thus, supportive treatments addressing agonizing pruritus are urgently needed.

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Autologous serum skin test reactions in chronic spontaneous urticaria differ from heterologous cell reactions

K. Baumann, J. Marcelino, P.S. Skov, M.C.P. Santos, I. Wyroslak, J. Scheffel, S. Altrichter, A. Woetmann, C. Costa, M. Maurer

doi : 10.1111/jdv.17131

Volume 35, Issue 6 p. 1338-1345

Autoimmune chronic spontaneous urticaria (CSU) is due to mast cell (MC)-activating autoantibodies, which are screened for by the autologous serum skin test (ASST) and basophil tests (BTs). Many CSU patients are positive in only one of these tests. How often this occurs and why is currently unknown.

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Cost-of-illness of atopic dermatitis in Germany: data from dermatology routine care

N. Mohr, M. Naatz, L. Zeervi, A. Langenbruch, T. Bieber, T. Werfel, A. Wollenberg, M. Augustin

doi : 10.1111/jdv.17203

Volume 35, Issue 6 p. 1346-1356

Progress in the management of atopic dermatitis (AD) and the recent introduction of the first biologic have raised interest in the costs of treating AD.

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Improvement of clinical and immunological parameters after allergen-specific immunotherapy in atopic dermatitis

K. Hajdu, A. Kapit?ny, Z. Dajnoki, L. Soltész, S. Bar?th, Z. Hendrik, I. Veres, A. Szegedi, K. G?sp?r

doi : 10.1111/jdv.17018

Volume 35, Issue 6 p. 1357-1361

Allergen immunotherapy (AIT) is considered a curative treatment in some atopic diseases, but in AD contradictory clinical results exist and the action of AIT has not been elucidated. In the literature, there is no evidence for parallel investigations of permeability barrier, cutaneous and blood immune responses after AIT in AD.

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Google search trends for itch in Europe: a retrospective longitudinal study

M.P. Pereira, S. Ziehfreund, M. Rueth, T. Ewering, F.J. Legat, J. Lambert, J. Elberling, L. Misery, E. Brenaut, E. Papadavid, S. Garcovich, A.W.M. Evers, J.A. Halvorsen, J.C. Szepietowski, A. Reich, M. Gonçalo, A. Lvov, S. Bobko, E. Serra-Baldrich, J. Wallengren, E. Savk, T. Leslie, S. St?nder, A. Zink, on behalf of the EADV Task Force Pruritus

doi : 10.1111/jdv.17077

Volume 35, Issue 6 p. 1362-1370

Itch is a common symptom in the general population. Affected individuals often do not seek medical consultation and rely on Internet searches to obtain information regarding their itch.

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Relationship between sensitive skin and sleep disorders, fatigue, dust, sweating, food, tobacco consumption or female hormonal changes: Results from a worldwide survey of 10 743 individuals

L. Misery, S. Morisset, S. Séité, E. Brenaut, A.-S. Ficheux, J. W. Fluhr, V. Delvigne, C. Taieb

doi : 10.1111/jdv.17162

Volume 35, Issue 6 p. 1371-1376

We aimed to investigate the roles of poorly known associated and triggering factors on sensitive skin in a large global population.

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Subclinical effects of adapalene-benzoyl peroxide: a prospective in vivo imaging study on acne micromorphology and transfollicular delivery

C.S.K. Fuchs, V.K. Ortner, F.S. Hansen, P.A. Philipsen, M. Haedersdal

doi : 10.1111/jdv.17140

Volume 35, Issue 6 p. 1377-1385

Adapalene–benzoyl peroxide (A-BPO) is a first-line topical treatment for acne vulgaris. In vivo reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) detect micromorphological changes over time and visualize transfollicular delivery.

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Investigation of gamma secretase gene complex mutations in German population with Hidradenitis suppurativa designate a complex polygenic heritage

S. Vural, M. Baumgartner, P. Lichtner, G. Eckstein, H. Hariry, W.C. Chen, T. Ruzicka, B. Melnik, G. Plewig, M. Wagner, K.A. Giehl

doi : 10.1111/jdv.17163

Volume 35, Issue 6 p. 1386-1392

Hidradenitis suppurativa (HS) is a chronic inflammatory disease affecting apocrine gland-bearing skin in the axilla, groin and under the breasts. Mutations of the gamma secretase gene complex, which is essential in the activation of Notch signalling pathways, were shown in some families with HS and in a few sporadic cases. Although an imbalance in Notch signalling is implicated in the pathogenesis, the exact mechanism of HS development is yet unknown.

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Differentially expressed proteins identified by TMT proteomics analysis in children with verrucous epidermal naevi

T. Yuan, M.-l. Cai, Y.-m. Sheng, X. Ding, T.-t. Shen, W.-r. Li, H. Huang, B. Liang, X.-j. Zhang, Q.-x. Zhu

doi : 10.1111/jdv.17112

Volume 35, Issue 6 p. 1393-1406

Verrucous epidermal naevi (VEN) are benign skin tumours, considered keratinocytic epidermal naevi, that appear at birth or early childhood. VEN may display a range of appearances, depending on patient age. Although the number of studies regarding VEN is increasing, the exact mechanism of VEN is still unknown.

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Corrigendum: Impact of modern systemic therapies and clinical markers on treatment outcome for metastatic melanoma in a real-world setting

I. Krakowski, M. Bottai, H. Habel, G. Masucci, A. Girnita, K.E. Smedby, H. Eriksson

doi : 10.1111/jdv.17209

Volume 35, Issue 6 p. 1407-1407

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Announcement

doi : 10.1111/jdv.17307

Volume 35, Issue 6 p. 1408-1408

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Announcement

doi : 10.1111/jdv.17308

Volume 35, Issue 6 p. 1409-1409

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Announcement

doi : 10.1111/jdv.17309

Volume 35, Issue 6 p. 1410-1410

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An Irish Department of Genito-Urinary Medicine in the COVID-19 Era

D. Moriarty, C. O'Connor, J. Bourke, M. Murphy, M. Horgan, S. Cremin

doi : 10.1111/jdv.17169

Volume 35, Issue 6 p. e353-e354

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Concerns and perceptions of patients with psoriatic disease during the COVID-19 pandemic: results from a two-wave survey by the National Psoriasis Foundation

G.C. Gondo, S.J. Bell, J. Slayden, G. Ullmann, A. Blauvelt

doi : 10.1111/jdv.17173

Volume 35, Issue 6 p. e354-e355

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Is SARS-CoV-2 screening test indicated for psoriasis patients candidate to biologic therapy?

S. Piaserico, P. Gisondi, S. Cazzaniga, G. Girolomoni, P.G. Calzavara-Pinton, L. Naldi

doi : 10.1111/jdv.17175

Volume 35, Issue 6 p. e355-e357

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Chilblains in a child with confirmed SARS-CoV-2 infection: a red flag for late-onset skin manifestation in previously infected individuals

I. Neri, F. Conti, A. Virdi, A. Guglielmo, L. Leonardi, I. Corsini, C. Ghizzi, L. Gabrielli, T. Lazzarotto, M. Lanari, A. Patrizi, C. Misciali

doi : 10.1111/jdv.17194

Volume 35, Issue 6 p. e357-e359

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Association between COVID-19 and chilblains: a case–control study

D. Ortega-Quijano, D. Fernandez-Nieto, J. Jimenez-Cauhe, J.L. Cortes-Cuevas, D. Marcos-Mencia, M. Rodriguez-Dominguez, G. Segurado-Miravalles, M. Fernandez-Guarino, P. Jaen-Olasolo

doi : 10.1111/jdv.17195

Volume 35, Issue 6 p. e359-e361

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Insights into Sars-CoV-2 vaccination in patients with chronic plaque psoriasis on systemic treatments

P. Gisondi, D. Geat, L. Naldi, S. Piaserico

doi : 10.1111/jdv.17200

Volume 35, Issue 6 p. e361-e362

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Risk of severe allergic reactions to COVID-19 vaccines among patients with allergic skin diseases – practical recommendations. A position statement of ETFAD with external experts

J. Ring, M. Worm, A. Wollenberg, J.P. Thyssen, T. Jakob, L. Klimek, C. Bangert, S. Barbarot, T. Bieber, M.S. de Bruin-Weller, P.V. Chernyshov, S. Christen-Zaech, M. Cork, U. Darsow, C. Flohr, R. F?lster-Holst, C. Gelmetti, U. Gieler, J. Gutermuth, A. Heratizadeh, D.J. Hijnen, L.B. von Kobyletzki, B. Kunz, C. Paul, L. De Raeve, J. Seneschal, D. Simon, P.I. Spuls, J.F. Stalder, A. Svensson, Z. Szalai, A. Taieb, A. Torrelo, M. Trzeciak, C. Vestergaard, T. Werfel, S. Weidinger, M. Deleuran

doi : 10.1111/jdv.17237

Volume 35, Issue 6 p. e362-e365

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May melanophages hinder the subclinical spread of lentigo maligna and lentigo maligna melanoma? Results from a pilot study

R. Moro, C. Requena, E. R?os-Vi?uela, E. Manrique-Silva, V. Traves, P.G. Calzavara-Pinton, G. Gualdi, E. Nagore

doi : 10.1111/jdv.17127

Volume 35, Issue 6 p. e365-e367

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Diagnosis of toenail onychomycosis by an immunochromatographic dermatophytes test strip

A. Mareschal, E. Scherer, T. Lihoreau, A.-P. Bellanger, L. Millon, F. Aubin

doi : 10.1111/jdv.17128

Volume 35, Issue 6 p. e367-e369

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SCORTEN in SJS/TEN: hypoalbuminaemia and oedema

C.B. Bunker, A.B. Chapman

doi : 10.1111/jdv.17136

Volume 35, Issue 6 p. e369-e369

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Epidermolysis bullosa acquisita: the most frequent pemphigoid disease in patients with dermal binding autoantibodies by indirect immunofluorescence microscopy on human salt-split skin in Tehran, Iran

M. Daneshpazhooh, S. Fazlolahi, H. Mahmoudi, I. Atefi, N. van Beek, K. Balighi, J. Taghizadeh Fazli, K. Kamyab, D. Zillikens, E. Schmidt

doi : 10.1111/jdv.17137

Volume 35, Issue 6 p. e370-e372

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Correlation of psoriasis severity with angiographic coronary artery disease complexity: a Cross-Sectional study

G. Sofidis, N. Stalikas, D. Papathemeli, E. Karagiannidis, A. Kartas, A. Papazoglou, N. Otountzidis, K. Natsis, E. Lazaridou, A. Patsatsi, G. Sianos

doi : 10.1111/jdv.17143

Volume 35, Issue 6 p. e372-e373

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Alemtuzumab, total skin electron beam, and non-myeloablative allogeneic haematopoietic stem-cell transplantation in advanced sezary syndrome: a retrospective cohort study

L.L. Thompson, C.X. Pan, M.S. Chang, G.E. Molina, Y.B. Chen, J.A. Barnes, S.T. Chen

doi : 10.1111/jdv.17144

Volume 35, Issue 6 p. e373-e375

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Association between atopic dermatitis and osteoarthritis among US adults in the 1999–2006 NHANES

J. Liu, A. Martin, A. Thatiparthi, J.J. Wu

doi : 10.1111/jdv.17147

Volume 35, Issue 6 p. e375-e377

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Violin spider: two car mechanic brothers bitten in Rome

A. Tammaro, G.A.R. Adebanjo, C. Chello, F.R. Parisella, P. Reen, H.P. Erasmus, A. Capalbo, G. De Marco

doi : 10.1111/jdv.17149

Volume 35, Issue 6 p. e377-e379

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A retrospective analysis of 925 cases of segmental vitiligo in a Chinese Han population

J. Ma, L. Cheng, Y.-Y. Wu, X.-Y. Cai, B. Liang, F.-L. Xiao

doi : 10.1111/jdv.17150

Volume 35, Issue 6 p. e379-e381

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Corticosteroid rescue therapy in relapsing hidradenitis suppurativa treated with adalimumab

M. Arenbergerova, S. Gkalpakiotis, E. Marques, P. Arenberger, R.A. Dahmen, A. Smetanova

doi : 10.1111/jdv.17151

Volume 35, Issue 6 p. e381-e383

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Scabies outbreak in Turkey in 2018–2019

C. Baykal, T. Atci, A. Kutlay, B. Baykut, Z. Türko?lu

doi : 10.1111/jdv.17152

Volume 35, Issue 6 p. e384-e385

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Acantholytic dyskeratotic epidermal naevus and striate palmoplantar keratoderma associated with DSG1 mutation: evidence for segmental type 2 mosaicism

A.-S. Blecic, J. Pernin, N. Jonca, J. Mazereeuw-Hautier, M.-L. Jullie, M. Cario-André, C. Léauté-Labrèze, F. Boralevi, F. Morice-Picard

doi : 10.1111/jdv.17153

Volume 35, Issue 6 p. e385-e387

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Clinical and genetic features of children with Hutchinson-Gilford progeria syndrome: a case series and a literature review

S. Wang, Z. Yang, Z. Xu, Y. Chu, Y. Liang, L. Wei, B. Zhang, Z. Xu, L. Ma

doi : 10.1111/jdv.17174

Volume 35, Issue 6 p. e387-e391

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Recurrent erythema nodosum leprosum associated with Mycobacterium indicus pranii vaccine in a case of leprosy: a rare paradox

R. Kothari, D. Vashisht, N. Pudasaini, R. Venugopal, G. Paliwal

doi : 10.1111/jdv.17176

Volume 35, Issue 6 p. e391-e393

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Dupilumab-associated hypereosinophilia in patients treated for moderate-to-severe atopic dermatitis

P. Marcant, P. Balayé, R. Merhi, F. Jendoubi, A. Nosbaum, N. Raison-Peyron, A. Du-Thanh, A. Lasek, M.-C. Ferrier le Bouedec, F. Tetart, A. Valois, S. Barbarot, A. Soria, M. Jachiet, D. Staumont-Sallé, for the GREAT Research Group

doi : 10.1111/jdv.17177

Volume 35, Issue 6 p. e394-e396

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The role of IL-8 in skin lesions of a patient with erythema elevatum diutinum

H. Kimura, R. Hayashi, Y. Tsuchida, A. Hasegawa, Y. Kabata, M. Tamura, R. Abe

doi : 10.1111/jdv.17179

Volume 35, Issue 6 p. e396-e399

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Line-field confocal optical coherence tomography of benign dermal melanocytic proliferations: a case series

C. Lenoir, J. Perez-Anker, G. Diet, L. Tognetti, E. Cinotti, A.L. Trépant, P. Rubegni, S. Puig, J.L. Perrot, J. Malvehy, V. del Marmol, M. Suppa

doi : 10.1111/jdv.17180

Volume 35, Issue 6 p. e399-e401

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Treatment of eosinophilic pustular folliculitis with benralizumab in a 13-year-old girl

C. Bürgler, C. Guillet, I. Kolm, M. Theiler, P. Schmid-Grendelmeier, S. Kroiss, L. Weibel

doi : 10.1111/jdv.17181

Volume 35, Issue 6 p. e401-e403

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Line-field confocal optical coherence tomography: a novel, non-invasive imaging technique for a rapid, in-vivo diagnosis of herpes infection of the skin

F. Lacarrubba, A.E. Verz?, D.F. Puglisi, G. Micali

doi : 10.1111/jdv.17182

Volume 35, Issue 6 p. e404-e406

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Nano is Bigger! Issues and challenges with nanoparticulate UV-filters (NP-UVF)

C. Surber, J. Plautz, S. D?hnhardt-Pfeiffer, U. Osterwalder

doi : 10.1111/jdv.17184

Volume 35, Issue 6 p. e406-e408

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Localized grey hair repigmentation (canities reversal) in patients with frontal fibrosing alopecia

M.A. Pastor-Nieto, S. Va?o-Galvan, A. G?mez-Zubiaur, E. Jiménez-Bl?zquez, O.M. Moreno-Arrones, V. Melgar-Molero

doi : 10.1111/jdv.17199

Volume 35, Issue 6 p. e408-e410

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