British Journal of Dermatology




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Editor's Choice – John Ingram – January 2024

doi : 10.1093/bjd/ljad460

Volume 190, Issue 1, January 2024

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Clinical reports: the overarching home for case series and case reports in the BJD

Ignacio Garcia-Doval ,1,2 Neil Rajan ,3,4 Hamish Hunter ,5 John Frew ,6 Luigi Naldi ,7,8 Jemima E. Mellerio 9 and Rod Hay

doi : 10.1093/bjd/ljad301

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Nemolizumab to target the itch–scratch cycle in paediatric atopic dermatitis

Antonia Lloyd-Lavery

doi : 10.1093/bjd/ljad319

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Unpacking factors contributing to melanoma overdiagnosis: does polygenic risk play a role?

Amelia K. Smit 1,2 and Anne E. Cust

doi : 10.1093/bjd/ljad431

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Assessment of treatment response on facial vitiligo, a step forward. But what about the neck?

Viktoria Eleftheriadou1 and Julien Seneschal

doi : 10.1093/bjd/ljad366

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Who has skin in the game? Expanding patient opportunities for research engagement is a win–win for dermatology

Annelise Colvin 1 and Lynn Petukhova

doi : 10.1093/bjd/ljad394

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Why are squamous cancers so aggressive in recessive dystrophic epidermolysis bullosa? Can we find new therapeutic approaches?

Ryan F.L. O’Shaughnessy

doi : 10.1093/bjd/ljad392

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Integrative medicine and self-care in the treatment of lymphatic filariasis-associated lymphoedema: an effective strategy!

Archana Singal and Kavita Bisherwal

doi : 10.1093/bjd/ljad374

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The role of enhancers in psoriasis and atopic dermatitis

Jennifer Y. Sui,1,2 Dawn Z. Eichenfield 1,2 and Bryan K. Sun

doi : 10.1093/bjd/ljad321

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Efficacy and safety of nemolizumab in paediatric patients aged 6–12 years with atopic dermatitis with moderate-to-severe pruritus: results from a phase III, randomized, double-blind, placebo-controlled, multicentre study

Atsuyuki Igarashi ,1 Toshio Katsunuma ,2 Takayo Matsumura 3 and Hiroshi Komazaki 3, for the Nemolizumab-JP04 Study Group

doi : 10.1093/bjd/ljad268

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Safety, tolerability, pharmacokinetics and efficacy of HB0017, a humanized monoclonal antibody that targets interleukin-17A, in healthy participants and patients with moderate-to-severe plaque psoriasis

Congjun Jiang,1 Yu Du,2 Xiaoyan Liu ,2 Jingjing Wang,2 Cuizhu Ge,2 Jingyue Xu,2 Shuoxiong Wang,2 Benke Li,2 Gege Zhu,1 Wanlu Zhang,1 Qiaoxiao Qian,2,3 Chi Ma,2 Xiangyang Zhu,2 Yifan Zhan2 and Yongmin Yang

doi : 10.1093/bjd/ljad315

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Does genetic risk modify the effect of skin screening on melanoma detection rates?

Nirmala Pandeya ,1,2 Jean Claude Dusingize ,1 Catherine M. Olsen ,1,2 Stuart MacGregor ,1 Rachel E. Neale ,1,2 Matthew H. Law 1,3,4 and David C. Whiteman

doi : 10.1093/bjd/ljad333

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Identification of eczema clusters and their association with filaggrin and atopic comorbidities: analysis of five birth cohorts

Sadia Haider ,1,2 Raquel Granell,3 John A. Curtin,4 John W. Holloway,5,6 Sara Fontanella,1,2 Syed Hasan Arshad,6,7,8 Clare S. Murray,4 Paul Cullinan,1 Stephen Turner,9,10 Graham Roberts,5,6,7 Angela Simpson4 and Adnan Custovic

doi : 10.1093/bjd/ljad326

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Global epidemiology of atopic dermatitis: a comprehensive systematic analysis and modelling study

Jingru Tian,1,2,3 Dingyao Zhang,4,5 Yi Yang,6 Yaqing Huang,7 Lu Wang,8 Xu Yao1 and Qianjin Lu

doi : 10.1093/bjd/ljad339

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Reliability and agreement testing of a new automated measurement method to determine facial vitiligo extent using standardized ultraviolet images and a dedicated algorithm

Quentin Marin Dit Bertoud,1 Clémence Bertold,2 Khaled Ezzedine, 3,4Amit G. Pandya,5,6 Marie Cherel,1 Alejandro Castillo Martinez,1 Marie-Anne Seguy,1 Marwa Abdallah,7 Jung Min Bae,8 Markus B?hm,9 Davinder Parsad ,10 David Rosmarin,11 Albert Wolkerstorfer,12 Philippe Bahadoran ,2 Manon Blaise,2 Pierre-Michel Dugourd,2 Valérie Philippo,2 Jean-Michel Delaval1 and Thierry Passeron

doi : 10.1093/bjd/ljad304

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Retrospective pharmacogenetic study of psoriasis highlights the role of KLK7 in tumour necrosis factor signalling

Haihan Zhang ,1 Matthew T. Patrick ,2 Trilokraj Tejasvi,2,3 Mrinal K. Sarkar,2 Rachael Wasikowski,2 Philip E. Stuart,2 Qinmengge Li,1 Xianying Xing,2 John J. Voorhees,2 Nicole L. Ward,4 Kevin He ,1 Xiang Zhou,1 Johann E. Gudjonsson,2,5 Rajan P. Nair,2 James T. Elder2,3 and Lam C. Tsoi

doi : 10.1093/bjd/ljad332

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MicroRNA-200b-mediated reversion of a spectrum of epithelial-to-mesenchymal transition states in recessive dystrophic epidermolysis bullosa squamous cell carcinomas

Julia Illmer ,1 Roland Zauner,1 Josefina Pi??n Hofbauer,1 Monika Wimmer,1 Stefanie Gruner,1 Michael Ablinger,1 Johannes Bischof,1 Sonja Dorfer,1 Stefan Hainzl,1 Vanessa Tober,1 Shir Bergson,2,3 Ofer Sarig,2 Liat Samuelov,2,3 Christina Guttmann-Gruber,1 Ruby Shalom-Feuerstein,4 Eli Sprecher,2,3 Ulrich Koller,1 Martin Laimer,1,5 Johann W. Bauer 1,5 and Verena Wally

doi : 10.1093/bjd/ljad335

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Self-care treatment for lymphoedema of lymphatic filariasis using integrative medicine

Saravu R. Narahari ,1 Madhur G. Aggithaya,1 Terence J. Ryan,2,3 Kunnathody Muralidharan,4 Peter J. Franks,5 Christine Moffatt6,7,8 and Peter S. Mortimer

doi : 10.1093/bjd/ljad310

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Hidradenitis suppurativa tarda: defining an understudied elderly population

Deveny A.Y. van der Weijden,1 Nicole D.K. Koerts ,1 Barbara C. van Munster ,2 Hessel H. van der Zee3 and Barbara Horv?th

doi : 10.1093/bjd/ljad317

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Roadmap to VIRTUAL-GLOBAL: coordinating VItiligo RegisTries for adUlts And chiLdren internationally

Viktoria Eleftheriadou,1 Iltefat Hamzavi,2 Jun Min Bae3 and Khaled Ezzedine

doi : 10.1093/bjd/ljad331

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When science and evidence is not enough: challenging the recommendations from the Commission on Human Medicines Isotretinoin Expert Working Group

Eugene Tan ,1 Harriet Kennedy2,3 and Marius Rademaker

doi : 10.1093/bjd/ljad363

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Global differences in tobacco use: who is using what?

Cecilia E. Medianfar 1 and Gregor B.E. Jemec

doi : 10.1093/bjd/ljad379

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Pruritus is associated with longer hospital stays and higher costs in psychiatric inpatients from the USA National Inpatient Sample (2012–2015): a cross-sectional study

Siri C. Choragudi , Luis F. Andrade and Gil Yosipovitch

doi : 10.1093/bjd/ljad329

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Atopic dermatitis and risk for headache disorders and migraines: a population-based cohort study in children and adults from the UK

Zelma C. Chiesa Fuxench ,1 Joy Wan ,2 Sonia Wang ,1 Maha N. Syed,1 Daniel B. Shin,1 Katrina Abuabara3 and Joel M. Gelfand1,

doi : 10.1093/bjd/ljad325

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Evaluating the usefulness of the Atopic Dermatitis Control Tool for assessing disease control in individuals with atopic dermatitis in Japan

Takeshi Nakahara ,1 Hiroyuki Fujita,2 Yuki Tajima2 and Kazuhiko Arima

doi : 10.1093/bjd/ljad344

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Drug survival of metformin in patients with hidradenitis suppurativa

Marina Senent-Valero ,1 Alicia Matijasevich ,2 Noelia Jara-Rico ,1 Francisca Sivera 3,4 and José C. Pascual

doi : 10.1093/bjd/ljad364

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A survey-based study on experiences with and perspectives toward medical providers among patients with hidradenitis suppurativa

Diana G. Marquez ,1 Nakisa B. Sadeghi,1 Linnea L. Westerkam,2 Franklin R. Blum,1 Angela Dresselhaus3 and Christopher J. Sayed

doi : 10.1093/bjd/ljad367

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Benefit of skin surgical revision in high-risk basal cell carcinoma according to histopathological margins

Bénédicte Reynaud ,1 Julien Jacquemus,2,3 Sylvie Chabaud,4 Yaelle Ouldbey,4 Sophie Darnis5 and Mona Amini-Adle1

doi : 10.1093/bjd/ljad372

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Characteristics and prognosis of first-time hospitalized patients with generalized pustular psoriasis: insights from national databases

Jeanette Halskou Haugaard,1 David Thein1 and Alexander Egeberg

doi : 10.1093/bjd/ljad384

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Machine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis

Michael J. Murphy ,1 Erica Hwang ,1 Katelyn Singh,1 Trinity Lee,1 Jeffrey M. Cohen 1,2 and William Damsky

doi : 10.1093/bjd/ljad389

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Comment on ‘Treatment of moderate-to-severe alopecia areata with baricitinib in preadolescent children’

Michael G. Buontempo ,1 Kristen Lo Sicco2 and Jerry Shapiro

doi : 10.1093/bjd/ljad323

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Comment on ‘Treatment of moderate-to-severe alopecia areata with baricitinib in preadolescent children with baricitinib’: authors’ reply

Leila Asfour,1 Laita Bokhari,1 Bevin Bhoyrul,1 Samantha Eisman,1 Anthony Moussa,1 Huw Rees2 and Rodney D. Sinclair

doi : 10.1093/bjd/ljad276

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Targeting interleukin (IL)-4/IL-13 in immune checkpoint inhibitor-induced bullous pemphigoid: a cautionary note on the beneficial effect of T helper 2 immunity in melanoma and immunotherapy

Christian F. Guerrero-Juarez,1,2 Parul K. Goyal2 and Kyle T. Amber

doi : 10.1093/bjd/ljad324

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Targeting interleukin (IL)-4/IL-13 in immune checkpoint inhibitor-induced bullous pemphigoid: a cautionary note on the beneficial effect of T helper 2 immunity in melanoma and immunotherapy: reply from the authors

William D. Shipman,1 Katelyn Singh,1 Jeffery M. Cohen,1 Jonathan Leventhal,1 William Damsky1,2 and Mary M. Tomayko

doi : 10.1093/bjd/ljad342

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The role of enhancers in eczema and psoriasis

doi : 10.1093/bjd/ljad467

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Nemolizumab reduces itch and improves other signs of atopic dermatitis in children aged 6–12 years

doi : 10.1093/bjd/ljad468

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A study looking at a possible new drug, HB0017, for the treatment of psoriasis

doi : 10.1093/bjd/ljad463

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Greater understanding about differences in the long-term course of eczema and their risk factors in children

doi : 10.1093/bjd/ljad464

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A study about how many people around the world have atopic dermatitis

doi : 10.1093/bjd/ljad462

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A new method to measure facial depigmentation in vitiligo

doi : 10.1093/bjd/ljad465

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A pharmacogenetic study of psoriasis supports the association between a gene (KLK7) and treatment response

doi : 10.1093/bjd/ljad469

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A short RNA molecule and tumour aggressiveness in people with epidermolysis bullosa

doi : 10.1093/bjd/ljad466

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Integrative treatment for filarial lymphoedema

doi : 10.1093/bjd/ljad461

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Hidradenitis suppurativa in older adults

doi : 10.1093/bjd/ljad470

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O01 Inborn errors of metabolism - Solving the puzzle of prolidase deficiency

Lachlan Byth and Tess McPherson

doi : 10.1093/bjd/ljad483.001

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O02 Assessing SleeP in INfants with moderate-severe atopic Dermatitis by Longitudinal Evaluation (The SPINDLE study)

Cathal O’Connor,1 Soraia Ventura,1 Mark O’Sullivan,1 Alan Irvine,2 Deirdre Murray,1 Jonathan Hourihane,3 Michelle Murphy4 and Geraldine Boylan

doi : 10.1093/bjd/ljad483.002

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O03 Sarcoidosis in a Boy with Severe Eczema on Dupilumab

Musarat Shahid, Penny Davis, Saleem Taibjee, Ceilia Moss and Malobi Ogboli

doi : 10.1093/bjd/ljad483.003

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O04 Vulval Psoriasis in Children: A Clinical Audit and Review of Literature

Michelle Wu1 and Gayle Fischer

doi : 10.1093/bjd/ljad483.004

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O05 A Qualitative Study of the Psychological Morbidity in Paediatric Survivors of Stevens Johnson Syndrome and Toxic Epidermal Necrolysis

Christopher Phillips,1 Abigail Mcniven,2 Michelle Yeung2 and Tess McPherson

doi : 10.1093/bjd/ljad483.005

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O06 Clinical phenotype of the Klippel-Trenaunay syndrome with mosaic PIK3R1 mutations

Pierre Vabres,1,2 Camille Engel,3 Didier Bessis,4 Fanny Morice-Picard4,5 Hélène Aubert,6 Bertrand Isidor,6 Alice Phan,7 Olivia Boccara,8 Juliette Mazereeuw-Hautier,9 Annabel Maruani-Raphaël,10 Eve Puzenat3 and Paul Kuentz3

doi : 10.1093/bjd/ljad483.006

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O07 CHILD syndrome and ILVEN: disorders on the same spectrum?

Pratima Paudel,1 Maryam Salimi,1 Rebecca Igbokwe,1 Saleem Taibjee,

doi : 10.1093/bjd/ljad483.007

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O08 Severely pruritic juvenile dermatomyositis

Katie Best1,2 and Suzy Leech

doi : 10.1093/bjd/ljad483.008

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O09 Targeted genetic therapy for congenital melanocytic naevi

Dale Bryant,1 Sara Barberan-Martin,2 Ruhina Maeshima,2 Ignacio Del Valle Torres,1 Mohammad Rabii,1 Aimie Sauvadet,1 Charalambos Demetriou,2 Nicole Kn?pfel,1 Fanis Michailides,1 Melissa Riachi,1 Davide Zecchin,1 Alan Pittman,3 Satyamaanasa Polubothu,4,2 Steve Hart2 and Veronica Kinsler

doi : 10.1093/bjd/ljad483.009

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O10 Multifocal congenital haemangiomas: expanding our understanding of “neonatal haemangiomatosis� – case series

Daniela Peeva, Gabriela Petrof and Lea Solman

doi : 10.1093/bjd/ljad483.010

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P01 Pigmented and purpuric patches in sun protected areas of a 9 year old child

Cristina Grechin,1 Ruth Law2 and Sinead Collins

doi : 10.1093/bjd/ljad483.011

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P02 Erythrokeratodermia variabilis et progressiva due to a pathogenic variant in GJB3 gene

Maria Bageta, Pablo Lopez Balboa, Debra Lomas, Gabriela Petrof and Anna E Martinez

doi : 10.1093/bjd/ljad483.012

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P03 EB or not EB? A report of two neonates with congenital blisters

Maria Bageta,1 Catherine Miller,2 Branavan Sivakumar,3 Pablo Lopez Balboa,1 Razan Dodein,4 Gabriela Petrof1 and Anna E Martinez

doi : 10.1093/bjd/ljad483.013

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P04 A Complex Case of Urticaria

Vidya Madhwapathi, Vicky Diba and Malobi Ogboli

doi : 10.1093/bjd/ljad483.014

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P05 Pre-visit online paediatric atopic dermatitis questionnaire – a feasibility study

Alex Gan,1 Emily Vaughan,2 Nataliya Heysa,2 Nina Mann,2 Jane Ravenscroft,2 Hywel Williams2 and Ting Seng Tang

doi : 10.1093/bjd/ljad483.015

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P06 Outcomes from a New Combined Allergy and Dermatology Clinic- A Retrospective Review

Su Yi Liew,1 Samid Ahmed,2 Alya Abdul-Wahab,1 Rosy Wells1 and Leila Ferguson1

doi : 10.1093/bjd/ljad483.016

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P08 Shingles in two children with no history of chicken pox

Mark Eisner and Sharmela Darné

doi : 10.1093/bjd/ljad483.017

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P09 A prospective study of Narrowband UVB (nb-UVB) Phototherapy for atopic dermatitis (AD) in children and adolescents.

Pavan Sambi,1 Katharine Warburton,1 Rachel Montgomery,1 Parisha Majeethia,2 Mia Thompson2 and Sheila Clark

doi : 10.1093/bjd/ljad483.018

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P10 New rash in a child of skin of colour

Dr Muhammad Fawad Aslam and Dr Susannah Hoey

doi : 10.1093/bjd/ljad483.019

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P11 A Rare and Serious Cause of “Blueberry Muffin Syndrome�

Jaimie Oldham,1 Anna Dunnigan,1 Elsa Barbosa,1 Sylvia Huang,1 Sasha Dhoat,1 Bryan McDonald,1 Edel O’Toole1,2 and Ravinder Atkar

doi : 10.1093/bjd/ljad483.020

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P12 Teleconsultations for Eczema in CHildren (TECH) feasibility study: a UK online survey of young people and parents

Natalie King Stokes,1 Aoife Daly,2 Sarah McCusker,3 Manrup Hunjan,4 Ellen Vincent,5 Ashima Lowe,6 Carolyn Charman,7 Susannah George,8 Lea Solman9 and Esther Burden-Teh

doi : 10.1093/bjd/ljad483.021

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P13 ‘Microneedle’ A new horizon of intradermal therapeutics

Waleed Faisal and Ryan Bamsey

doi : 10.1093/bjd/ljad483.022

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P14 Midface Toddler Excoriation Syndrome (MiTES): a new mimic of non-accidental injury

a new mimic of non-accidental injury Janine Dewar,1 Alia Ahmed,2 Celia Moss3,4 and Lea Solman

doi : 10.1093/bjd/ljad483.023

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P15 A Case of Juvenile Dermatomyositis in a 15-year old African-descent Girl

Evangelia Vetsiou, Kate Armon and Julia Gass

doi : 10.1093/bjd/ljad483.024

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P16 Hypopigmented Mycosis Fungoides in a Caucasian child

Sheena Bhadresha, Zahra Moledina and Angela Tewari

doi : 10.1093/bjd/ljad483.025

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P17 A Multisite Service Evaluation of Paediatric Teleconsultations

Sarah McCusker,1 Aoife Daly,2 Natalie King,3 Manrup Hunjan,4 Lea Solman,5 Esther Burden-Teh,6 Susannah George7 and Gordon Hale8

doi : 10.1093/bjd/ljad483.026

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P18 Giant Periocular Juvenile Xanthogranulomas Treated with Trametinib

Dr. Pratima Poudel, Dr. Gerard Millen and Malobi Ogboli

doi : 10.1093/bjd/ljad483.027

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P19 Spontaneous regression of aleukaemic cutis leukaemia in a male infant

Jadesola Oyedepo,1 Maria Bageta,2 Maanasa Polubothu,3,4 Jonathan Tan,5 Michael Gattens,6 Samantha Levine7 and Liz Hook

doi : 10.1093/bjd/ljad483.028

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P20 A Rare Case of Hereditary Mucoepithelial Dysplasia With Long Term Follow Up

Evangelia Vetsiou, Emily Hayes, Simon Holden and Nigel Burrows

doi : 10.1093/bjd/ljad483.029

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P21 Bi-allelic TUFT1 variants in two siblings with woolly hair and skin fragility

Pablo Lopez Balboa,1 Maria L Bageta,1 John A McGrath,2 Gabriela Petrof1 and Anna E Martinez1

doi : 10.1093/bjd/ljad483.030

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P23 Successful Control of Systemic Mastocytosis Symptoms in a Two-Year-Old with Omalizumab

Miteshkumar Ramwani,1 Constantinos Kotsapas,2 Sheila Clark,3 Jack Bartram1 and Lea Solman

doi : 10.1093/bjd/ljad483.031

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P24 Improving the patient pathway for timely referral and management of infantile haemangioma

Jacqueline Scott-Bazaldua and Anna Dubois

doi : 10.1093/bjd/ljad483.032

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P25 Two cases of multicentric dermatofibrosarcoma Protuberans (DFSP) and adenosine deaminase deficient-severe combined immunodeficiency (ADA-SCID) in a tertiary centre

Louis Gardner, Anna Dubois, Suzy Leech, Mary Slatter, Andy Gennery and Zohreh Nademi

doi : 10.1093/bjd/ljad483.033

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P26 A life threatening case of Von Zumbusch psoriasis

Juliana Graciani Moura

doi : 10.1093/bjd/ljad483.034

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P27 Successful treatment of severe eczema and plane warts with Dupilumab in a child with Dedicator of Cytokinesis 8 (DOCK8) deficiency (Autosomal recessive form of hyper-IgE syndrome)

Jadesola Oyedepo,1 Austen Worth2 and Lea Solman

doi : 10.1093/bjd/ljad483.035

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P28 Congenital Cellular Plexiform Schwannoma Masquerading as Infantile Haemangioma – A Case Report

Jadesola Oyedepo,1 Olga Slater2 and Lea Solman

doi : 10.1093/bjd/ljad483.036

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P29 Erosive and vesicular dermatitis

Christiana Stavrou1 and Suzy Leech

doi : 10.1093/bjd/ljad483.037

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P30 Trouble with skin: Do parents understand the impact skin conditions have on children’s quality of life?

Marion Leahy and Annette Murphy

doi : 10.1093/bjd/ljad483.038

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P31 Association of atopic dermatitis with thyroid diseases: a systematic review and meta-analysis

Ching-Chi Chi1,2 and Tzu-Yu Wang

doi : 10.1093/bjd/ljad483.039

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P32 Bullous Pemphigoid in Childhood and Infancy. A case of a 4-months old post vaccination

Sondos Hassanin,1 Arnav Katira2 and Nicola Hardcastle

doi : 10.1093/bjd/ljad483.040

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P33 A lichenoid eruption and severe eczema in association with IMAGe syndrome

Garret O’Connell and Mary Bennett

doi : 10.1093/bjd/ljad483.041

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