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Aging and neuronal death
Fang Fang, Robert Usselman, Renee Reijo Pera
doi : 10.18632/aging.205433
Volume 15, Issue 23
Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema
Alberta Palazzo, Gabriela Makulyte, Delphine Goerhig, Jean-Jacques Médard, Vincent Gros, François Trottein, Serge Adnot, David Vindrieux, Jean-Michel Flaman, David Bernard
doi : 10.18632/aging.205259
Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence
Franziska Hornung, Nilay Köse-Vogel, Claude Jourdan Le Saux, Antje Häder, Lea Herrmann, Luise Schulz, Lukáš Radosa, Thurid Lauf, Tim Sandhaus, Patrick Samson, Torsten Doenst, Daniel Wittschieber, Gita Mall, Bettina Löffler, Stefanie Deinhardt-Emmer
doi : 10.18632/aging.205297
Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction
Geum-Hwa Lee, Hwa-Young Lee, Young-Je Lim, Ji-Hyun Kim, Su-Jin Jung, Eun-Soo Jung, Soo-Wan Chae, Juwon Lee, Junghyun Lim, Mohammad Mamun Ur Rashid, Kyung Hyun Min, Han-Jung Chae
doi : 10.18632/aging.205343
Geum-Hwa Lee, Hwa-Young Lee, Young-Je Lim, Ji-Hyun Kim, Su-Jin Jung, Eun-Soo Jung, Soo-Wan Chae, Juwon Lee, Junghyun Lim, Mohammad Mamun Ur Rashid, Kyung Hyun Min, Han-Jung Chae
Michaela E. Copp, Jacqueline Shine, Hannon L. Brown, Kirti R. Nimmala, Oliver B. Hansen, Susan Chubinskaya, John A. Collins, Richard F. Loeser, Brian O. Diekman
doi : 10.18632/aging.205394
Cabozantinib prevents AGEs-induced degradation of type 2 collagen and aggrecan in human chondrocytes
Yang Dong, Lianfang Lin, Yuan Ji, Xu Cheng, Zhiwu Zhang
doi : 10.18632/aging.205186
Down-regulation of EZH2 genes targeting RUNX3 affects proliferation, invasion, and metastasis of human colon cancer cells by Wnt/β-catenin signaling pathway
Guanli Liang, Lei Han, Ming Qu, Jun Xue, Dandan Xu, Xueliang Wu, Yonggang Lu
doi : 10.18632/aging.205197
Atorvastatin mitigates memory deficits and brain monocyte infiltration in chronic hypercholesterolemia
Fengchao Gong, Qian Shi, Xiaojie Mou, Kang Wang, Qianqian Wang, Haitao Wang
doi : 10.18632/aging.205217
Adiponectin inhibits LPS-induced nucleus pulposus cell pyroptosis through the miR-135a-5p/TXNIP signaling pathway
Shuang Wu, Shida Liu, Rui Huang, Youbing Zhou, Yongcheng Zou, Wei Yang, Jian Zhang
doi : 10.18632/aging.205226
The antioxidant Glycitin protects against intervertebral disc degeneration through antagonizing inflammation and oxidative stress in nucleus pulposus cells
Wei Zhao, Yanpei Li, Xiang Cheng, Hui Wei, Peng Li, Lixia Fan, Kaiwen Liu, Shuai Zhang, Hao Wang
doi : 10.18632/aging.205251
A glycosylation-related signature predicts survival in pancreatic cancer
Huidong Hu, Bingsheng He, Mingang He, Hengmin Tao, Baosheng Li
doi : 10.18632/aging.205258
Involvement of RFC3 in tamoxifen resistance in ER-positive breast cancer through the cell cycle
Jintao Zhu, Lei Ye, Shishen Sun, Jie Yuan, Jianfeng Huang, Zhiqiang Zeng
doi : 10.18632/aging.205260
PBRM1 mutation and WDR72 expression as potential combinatorial biomarker for predicting the response to Nivolumab in patients with ccRCC: a tumor marker prognostic study
Qinzheng Chang, Jiajia Sun, Shuo Zhao, Luchao Li, Nianzhao Zhang, Lei Yan, Yidong Fan, Jikai Liu
doi : 10.18632/aging.205261
Prognostic role of long non-coding RNA USP30-AS1 in ovarian cancer: insights into immune cell infiltration in the tumor microenvironment
Jian Xiong, Junyan Chen, Xiang Sun, Rui Zhao, Kefei Gao
doi : 10.18632/aging.205262
Integrating scRNA-seq and bulk RNA-seq to characterize infiltrating cells in the colorectal cancer tumor microenvironment and construct molecular risk models
Qi Wang, Yi-Fan Zhang, Chen-Long Li, Yang Wang, Li Wu, Xing-Ru Wang, Tai Huang, Ge-Liang Liu, Xing Chen, Qi Yu, Pei-Feng He
doi : 10.18632/aging.205263
Identification and validation of feature genes associated with M1 macrophages in preeclampsia
Panpan Hu, Shanshun Luo, Guangjin Qu, Qiqi Luo, Yu Tian, Kun Huang, Tingting Sun
doi : 10.18632/aging.205264
Prognostic significance and immune characteristics of APOE in gastric cancer
Xiulan Peng, Zhen Cai, Duansi Chen, Fei Ye, Lifeng Hong
doi : 10.18632/aging.205265
Long noncoding RNA MEG8 induces an imbalance of Th17/Treg cells through the miR-107/STAT3 axis in Henoch-Schonlein purpura rats
Mingyu Jiang, Jicheng Dai, Chunming Jiang, Yanbo Pan, Mingyong Ren, Mengnan Xing
doi : 10.18632/aging.205266
S14G-humanin alleviates acute lung injury by inhibiting the activation of NF-κB
Yunlong Wu, Hui Zhang, Lingbo Guan, Xiangli Jia, Mei Wang
doi : 10.18632/aging.205267
lncRNA TUSC7 regulates oxidative stress level by targeting miR-23b in colorectal cancer and thus inhibits cell proliferation, migration and invasion
Haopeng Ye, Weidan Ren, Guiwei Liu, Qingjin Guo
doi : 10.18632/aging.205270
HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2
Peiyi Yin, Yongbin Wu, Xiang Long, Shuqiang Zhu, Shiwei Chen, Feng Lu, Kun Lin, Jianjun Xu
doi : 10.18632/aging.205272
Crosstalk of cuproptosis-related prognostic signature and competing endogenous RNAs regulation in hepatocellular carcinoma
Jun Zhu, Jingyan Wang, Hong Liu, Tong Lei, Jiankang Yang, Sheng Lan, Haokun Jian, Hanlu Fang, Yu Zhang, Kuiwu Ren, Fei Zhong
doi : 10.18632/aging.205273
Has-miR-300—GADD45B promotes melanoma growth via cell cycle
Long Chen, Chenglong Fang, Xiaoxue Yuan, Mengqi Liu, Ping Wu, Li Zhong, Zhiyong Chen
doi : 10.18632/aging.205276
SEMA3G, downregulated by ncRNAs, correlates with favorable prognosis and tumor immune infiltration in kidney renal clear cell carcinoma
Jian Yuan, Guorong Yuan
doi : 10.18632/aging.205277
Cathepsin V drives lung cancer progression by shaping the immunosuppressive environment and adhesion molecules cleavage
Lifei Zhu, Qi Zeng, Jinxiang Wang, Fan Deng, Shi Jin
doi : 10.18632/aging.205278
lncRNA GPRC5D-AS1 as a ceRNA inhibits skeletal muscle aging by regulating miR-520d-5p
Miao Yu, Xiuting He, Ting Liu, Jie Li
doi : 10.18632/aging.205279
Modified Chaishao Liujunzi Decoction inhibits bile acid-induced gastric intestinal metaplasia: from network prediction to experimental verification
Zheyu Sun, Yuna Liu, Haiyan Deng, Shaohua Wang, Jing Zhang, Chongyi Xing, Chunfeng Xu
doi : 10.18632/aging.205285
Rewiring of IGF1 secretion and enhanced IGF1R signaling induced by co-chaperone carboxyl-terminus of Hsp70 interacting protein in adipose-derived stem cells provide augmented cardioprotection in aging-hypertensive rats
Parthasarathi Barik, Wei-Wen Kuo, Chia-Hua Kuo, Dennis Jine-Yuan Hsieh, Cecilia Hsuan Day, Jayasimharayalu Daddam, Michael Yu-Chih Chen, V. Vijaya Padma, Marthandam Asokan Shibu, Chih-Yang Huang
doi : 10.18632/aging.205287
Association of modifiable risk factors with obstructive sleep apnea: a Mendelian randomization study
Ye Li, Yuyang Miao, Jin Tan, Qiang Zhang
doi : 10.18632/aging.205288
Obesity, birth weight, and lifestyle factors for frailty: a Mendelian randomization study
Yingzhen Gu, Zuozhi Li, Aimin Dang, Wei Zhang, Jinxing Liu, Xiaorong Han, Yifan Li, Naqiang Lv
doi : 10.18632/aging.205290
Transcriptome research of human amniocytes identifies hub genes associated with developmental dysplasia in down syndrome
Zhenglong Guo, Hai Xiao, Wenke Yang, Tao Li, Bingtao Hao, Shixiu Liao
doi : 10.18632/aging.205291
Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer
Longjun Zang, Baoming Zhang, Yanling Zhou, Fusheng Zhang, Xiaodong Tian, Zhongming Tian, Dongjie Chen, Qingwang Miao
doi : 10.18632/aging.205293
Comprehensive analysis reveals key genes and environmental toxin exposures underlying treatment response in ulcerative colitis based on in-silico analysis and Mendelian randomization
Yizhou Huang, Jie Liu, Dingbao Liang
doi : 10.18632/aging.205294
Gypenoside IX restores Akt/GSK-3β pathway and alleviates Alzheimer’s disease-like neuropathology and cognitive deficits
Ling Lei, Yong Luo, Dongkun Kang, Fumin Yang, Dongli Meng, Jian-Zhi Wang, Rong Liu, Xiaochuan Wang, Hong-Lian Li
doi : 10.18632/aging.205295
The positive efficacy of dexmedetomidine on the clinical outcomes of patients undergoing renal transplantation: evidence from meta-analysis
Shanshan Guo, Degong Jia, Xueqi Liu, Li Gao, Huaying Wang, Chaoyi Chen, Yonggui Wu
doi : 10.18632/aging.205296
Integrated bioinformatics and experiment revealed that cuproptosis is the potential common pathogenesis of three kinds of primary cardiomyopathy
Mengxi Wang, Xiaozhuo Xu, Jianghong Li, Ziwei Gao, Yuhan Ding, Xiaohu Chen, Qian Xiang, Le Shen
doi : 10.18632/aging.205298
Two lncRNA signatures with cuproptosis as a novel prognostic model and clinicopathological value for endometrioid endometrial adenocarcinoma
Hongrong Wu, Ruilin Lin, Liangli Hong
doi : 10.18632/aging.205299
Integrated multi-omics analysis for lung adenocarcinoma in Xuanwei, China
Boyi Jiang, Jiapeng Yang, Rui He, Dong Wang, Yunchao Huang, Guangqiang Zhao, Mingjie Ning, Teng Zeng, Guangjian Li
doi : 10.18632/aging.205300
Delivering umbilical cord mesenchymal stem cell exosomes through hydrogel ameliorates vaginal atrophy in ovariectomized rats
Tao Zhang, Dandan Li, Yanting Wang, Chi Zhang, Wenlan Yang, Guolan Gao
doi : 10.18632/aging.205302
DOK7, a target of miR-299-5p, suppresses the progression of bladder cancer
Xuemei Tian, Dan Liu, Peng He, Lijun Li, Yu Wang, Mingxing Qiu
doi : 10.18632/aging.205304
Specific knockout of notch-1 attenuates non-alcoholic fatty liver disease by promoting SHP2 phosphorylation
Qian Gao, Yonggang Lu, Weiling Zhou
doi : 10.18632/aging.205305
Single-cell dissection reveals the role of aggrephagy patterns in tumor microenvironment components aiding predicting prognosis and immunotherapy on lung adenocarcinoma
Xinti Sun, Fei Meng, Minyu Nong, Hao Fang, Chenglu Lu, Yan Wang, Peng Zhang
doi : 10.18632/aging.205306
Melatonin exhibits partial protective effects against gemcitabine- and cisplatin-induced kidney and reproductive injuries in mice
Shao-Chuan Wang, Hsuan-Chih Hsu, Ya-Chuan Chang, Chia-Ying Yu, Chien-Te Liu, Wen-Wei Sung
doi : 10.18632/aging.205307
Integration of genomics and transcriptomics highlights the crucial role of chromosome 5 open reading frame 34 in various human malignancies
Yilin Li, Yong Zhang, Dan Sun, Xiaofeng Zhang, Shangqin Long, Jiuxiang Feng, Zhongmin Wang
doi : 10.18632/aging.205310
MicroRNA 211-5p inhibits cancer cell proliferation and migration in pancreatic cancer by targeting BMP2
Dan Li, Chen Luo, Jianyong Deng, Yongkang Xu, Shumin Fu, Kan Liu, Jianbing Wu
doi : 10.18632/aging.205320
Integrative analysis of single-cell and bulk RNA seq to reveal the prognostic model and tumor microenvironment remodeling mechanisms of cuproptosis-related genes in colorectal cancer
Bowen Chu, Yaohui Wang, Jiwen Yang, Bohan Dong
doi : 10.18632/aging.205324
The effect of nutritional biochemical indexes on the hospitalization outcome of COVID-19
Peng Wang, Wenying Shi, Xiaodi Zhao, Guanan Zhao, Lidan Ding, Sen Zhang, Jiaxin Li
doi : 10.18632/aging.205335
MiR-203a-3p attenuates apoptosis and pyroptosis of chondrocytes by regulating the MYD88/NF-κB pathway to alleviate osteoarthritis progression
Jiayi Chen, Zhutong Liu, He Sun, Mange Liu, Jiangliang Wang, Chenxiao Zheng, Xuewei Cao
doi : 10.18632/aging.205373
Traditional herbs: mechanisms to combat cellular senescence
Lei Wang, Jiahui Wang, Zhihui Yang, Yue Wang, Tiejian Zhao, Weisheng Luo, Tianjian Liang, Zheng Yang
doi : 10.18632/aging.205269
Retraction for: Exosomes derived from human umbilical cord mesenchymal stem cells promote osteogenesis through the AKT signaling pathway in postmenopausal osteoporosis
Shi-Wei Ren, Guang-Qing Cao, Qing-Run Zhu, Min-Gang He, Fang Wu, Su-Mei Kong, Zhao-Yan Zhang, Qiang Wang, Feng Wang
doi : 10.18632/aging.205437
