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Artificial intelligence for aging research in cancer drug development
Dorsa Shirini, Lawrence H. Schwartz, Laurent Dercle
doi : 10.18632/aging.204914
Volume 15, Issue 22
Chronological aging impacts abundance, function and microRNA content of extracellular vesicles produced by human epidermal keratinocytes
Taku Nedachi, Christelle Bonod, Julie Rorteau, Wafae Chinoune, Yuri Ishiuchi, Sandrine Hughes, Benjamin Gillet, Nicolas Bechetoille, Dominique Sigaudo-Roussel, Jérôme Lamartine
doi : 10.18632/aging.205245
Tat-heat shock protein 10 ameliorates age-related phenotypes by facilitating neuronal plasticity and reducing age-related genes in the hippocampus
Hyo Young Jung, Hyun Jung Kwon, Kyu Ri Hahn, Woosuk Kim, Dae Young Yoo, Yeo Sung Yoon, Dae Won Kim, In Koo Hwang
doi : 10.18632/aging.205182
Contribution of membrane raft redox signalling to visfatin-induced inflammasome activation and podocyte injury
Saisudha Koka, Sreenidhi Surineni, Gurinder Bir Singh, Krishna M. Boini
doi : 10.18632/aging.205243
Nectandrin B significantly increases the lifespan of Drosophila - Nectandrin B for longevity
Ji-Seon Ahn, Nasir Uddin Mahbub, Sura Kim, Han-Byeol Kim, Jong-Soon Choi, Hea-Jong Chung, Seong-Tshool Hong
doi : 10.18632/aging.205234
Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism
Ramya Potabattula, Andreas Prell, Marcus Dittrich, Caroline Nava, Christel Depienne, Yosra Bejaoui, Nady El Hajj, Thomas Hahn, Martin Schorsch, Thomas Haaf
doi : 10.18632/aging.205275
Hypoxic BMSC-derived exosomal miR-652-3p promotes proliferation and metastasis of hepatocarcinoma cancer cells via targeting TNRC6A
Mei Li, Pengtao Zhai, Xudong Mu, Juanrong Song, Huilin Zhang, Juan Su
doi : 10.18632/aging.205025
Identification of mitochondrial-related signature and molecular subtype for the prognosis of osteosarcoma
Xiaokun Zhao, Jian Zhang, Jiahao Liu, Qi Chen, Changxiong Cai, Xinxin Miao, Tianlong Wu, Xigao Cheng
doi : 10.18632/aging.205143
Prognostic hub gene CBX2 drives a cancer stem cell-like phenotype in HCC revealed by multi-omics and multi-cohorts
Qingren Meng, Qian Zhou, Xi Chen, Jun Chen
doi : 10.18632/aging.205173
Peptidome analysis reveals critical roles for peptides in a rat model of intestinal ischemia/reperfusion injury
Jiaxuan Zhang, Xiaoqi Jiang, Yang Yang, Lei Yang, Bing Lu, Yannan Ji, Leijun Guo, Fan Zhang, Jianhua Xue, Xiaofei Zhi
doi : 10.18632/aging.205200
Silencing of Dicer enhances dacarbazine resistance in melanoma cells by inhibiting ADSL expression
Yu-Wen Yeh, Tung-Wei Hsu, Yen-Hao Su, Chih-Hsin Wang, Po-Hsiang Liao, Ching-Feng Chiu, Po-Chen Tseng, Tim-Mo Chen, Woan-Ruoh Lee, Yuan-Sheng Tzeng
doi : 10.18632/aging.205207
TJP3 promotes T cell immunity escape and chemoresistance in breast cancer: a comprehensive analysis of anoikis-based prognosis prediction and drug sensitivity stratification
Liu Chaojun, Li Pengping, Li Yanjun, Zhu Fangyuan, He Yaning, Shao Yingbo, Chen Qi, Liu Hui
doi : 10.18632/aging.205208
The necroptosis signature and molecular mechanism of lung squamous cell carcinoma
Guo-Qiang Song, Hua-Man Wu, Ke-Jie Ji, Tian-Li He, Yi-Meng Duan, Jia-Wen Zhang, Guo-Qiang Hu
doi : 10.18632/aging.205210
A novel telomere-related genes model for predicting prognosis and treatment responsiveness in diffuse large B-cell lymphoma
Zhijia Zhao, Xiaochen Shen, Siqi Zhao, Jinhua Wang, Yuqin Tian, Xiaobo Wang, Bo Tang
doi : 10.18632/aging.205211
EphA2 as a phase separation protein associated with ferroptosis and immune cell infiltration in colorectal cancer
Yanling Li, Qiu Peng, Lujuan Wang
doi : 10.18632/aging.205212
Crucial role of hsa-mir-503, hsa-mir-1247, and their validation in prostate cancer
Ping Hu, Tao Wang, Hui Yan, Ying Huang, Yanjiao Zhao, Yuanyuan Gao
doi : 10.18632/aging.205213
Multi-omics analysis of the oncogenic role of optic atrophy 1 in human cancer
Ziyi Wu, Nuo Xu, Guoqing Li, Wen Yang, Chen Zhang, Hua Zhong, Gen Wu, Fei Chen, Dianqing Li
doi : 10.18632/aging.205214
The upregulation of circFoxp1 influences keloid by promoting cell proliferation
Jing Zhang, Qianyi Bao, Nan Song, Chunming Li, Jing Ma
doi : 10.18632/aging.205215
Identification of topoisomerase 2A as a novel bone metastasis-related gene in liver hepatocellular carcinoma
Jinyan Feng, Xianfu Wei, Yongheng Liu, Yanting Zhang, Guanghao Li, Yao Xu, Peng Zhou, Jin Zhang, Xiuxin Han, Chao Zhang, Yan Zhang, Guowen Wang
doi : 10.18632/aging.205216
Comprehensive analysis of ZNF692 as a potential biomarker associated with immune infiltration in a pan cancer analysis and validation in hepatocellular carcinoma
Hongjie Cai, Song Chen, Zhiqiang Wu, Fan Wang, Shuangyan Tang, Dongbing Li, Dongliang Wang, Wenbo Guo
doi : 10.18632/aging.205218
Inhibition of UFM1 expression suppresses cancer progression and is linked to the dismal prognosis and immune infiltration in oral squamous cell carcinoma
Di Ke, Hao-Han Guo, Ni Jiang, Rong-Shu Shi, Teng-Yang Fan
doi : 10.18632/aging.205219
Identification of tryptophan metabolism-related genes in immunity and immunotherapy in Alzheimer’s disease
Zhenyan Song, Zixuan Wu, Rongsiqing Luo, Chunxiang He, Ze Li, Miao Yang, Wenjing Yu, Jiawei He, Sisi Deng, Shaowu Cheng
doi : 10.18632/aging.205220
Identification of aneuploidy-related gene signature to predict survival in head and neck squamous cell carcinomas
doi : 10.18632/aging.205221
Clinical significance and immune landscape of angiogenesis-related genes in bladder cancer
Gang Liu, Tingting Zhang, Dingwen Gui, Qin Liu
doi : 10.18632/aging.205222
Prevalence and risk factors of bone metastasis and the development of bone metastatic prognostic classification system: a pan-cancer population study
Zhouyang Hu, Sheng Yang, Zhipeng Xu, Xiaoling Zhang, Hong Wang, Guoxin Fan, Xiang Liao
doi : 10.18632/aging.205224
SEL1L3 as a link molecular between renal cell carcinoma and atherosclerosis based on bioinformatics analysis and experimental verification
doi : 10.18632/aging.205227
Hypoxia-regulated exosomes mediate M2 macrophage polarization and promote metastasis in chondrosarcoma
Sheng-Mou Hou, Chih-Yang Lin, Yi-Chin Fong, Chih-Hsin Tang
doi : 10.18632/aging.205230
Investigating EGF and PAG1 as necroptosis-related biomarkers for diabetic nephropathy: an in silico and in vitro validation study
Yuejun Wang, Linlin Zhang, Zhiping Peng
doi : 10.18632/aging.205233
Electroacupuncture ameliorates AOM/DSS-induced mice colorectal cancer by inhibiting inflammation and promoting autophagy via the SIRT1/miR-215/Atg14 axis
Jinxiao Li, Ying Han, Minfeng Zhou, Na Liu, Huarong Li, Guichen Huang, Zhaomin Yu, Dan Luo, Haiming Zhang, Xiangyi Zheng, Fengxia Liang, Rui Chen
doi : 10.18632/aging.205236
A prognostic risk model for programmed cell death and revealing TRIB3 as a promising apoptosis suppressor in renal cell carcinoma
Qingfeng Fu, Bocun Yi, Qiang Su, Yue Huang, Lin Wang, Zhihong Zhang
doi : 10.18632/aging.205237
Qi Fu Yin ameliorates neuroinflammation through inhibiting RAGE and TLR4/NF-κB pathway in AD model rats
Chunxiang He, Wenjing Yu, Miao Yang, Ze Li, Jingping Yu, Dayuan Zhong, Sisi Deng, Zhenyan Song, Shaowu Cheng
doi : 10.18632/aging.205238
Inhibiting KLRB1 expression is associated with impairing cancer immunity and leading to cancer progression and poor prognosis in breast invasive carcinoma patients
Jin-Rong He, Dan Li, Qun-Xian Zhang, Tao Liu, Yu Ding, Chuang-Yan Wu, Shan-Shan Chen, Jiu-Ling Chen
doi : 10.18632/aging.205239
Molecular characteristics and clinical implications of serine/arginine-rich splicing factors in human cancer
Jinjin Zhang, Zhicheng Fang, Congkuan Song
doi : 10.18632/aging.205241
Prognostic significance and immunoinfiltration analysis of genes associated with epithelial-mesenchymal transition and energy metabolism in bladder urothelial carcinoma
Yifan Qiu, Wei Ye, Chao Wang, Jin Zang
doi : 10.18632/aging.205242
circSLCO1B7 suppresses the malignant progression of hepatocellular carcinoma via the miR-556-3p/DAB2IP axis
Linling Ju, Qian Zhou, Qianyi Qi, Yongjun She, Weihua Cai, Yali Cao, Rujian Lu, Jianguo Shao, Lin Chen
doi : 10.18632/aging.205244
Immune microenvironment heterogeneity reveals distinct subtypes in neuroblastoma: insights into prognosis and therapeutic targets
Yanlan Yang, Huamei Li, Donghui Zheng, Xuemei Li, Hongyan Liu
doi : 10.18632/aging.205246
Comprehensive analysis of tertiary lymphoid structures-related genes for prognostic prediction, molecular subtypes and immune infiltration in gastric cancer
Qingde Zhou, Lan Lan, Wei Wang, Xinchang Xu, Wei Wang
doi : 10.18632/aging.205247
BDH1-mediated βOHB metabolism ameliorates diabetic kidney disease by activation of NRF2-mediated antioxidative pathway
Sheng-Rong Wan, Fang-Yuan Teng, Wei Fan, Bu-Tuo Xu, Xin-Yue Li, Xiao-Zhen Tan, Man Guo, Chen-Lin Gao, Chun-Xiang Zhang, Zong-Zhe Jiang, Yong Xu
doi : 10.18632/aging.205248
Regulatory mechanisms of miR-212-3p on the secretion of inflammatory factors in monocyte-macrophages and the directed differentiation into osteoclasts in ankylosing spondylitis
Jianli Xie, Jinrong Xu, Haiying Chen
doi : 10.18632/aging.205249
Effect of Nrf2 on brain injury induced by hydraulic shock via regulation of mitophagy and apoptosis
Erwei Zhang, Tongmao Wu, Yayu Zhuo, Junling Cui, Si Sun, Guobiao Wu, Gengshen Zhang
doi : 10.18632/aging.205250
Predicting the prognosis in patients with sepsis by an endoplasmic reticulum stress gene signature
Jian Liu, Hao Wang, Huimin Xiao, Li Ji, Yonghui Yao, Chunshui Cao, Yong Liu, Liang Huang
doi : 10.18632/aging.205252
Plumbagin alleviates temporomandibular joint osteoarthritis progression by inhibiting chondrocyte ferroptosis via the MAPK signaling pathways
Tiehan Cui, Yun Lan, Fei Yu, Suai Lin, Jiaxuan Qiu
doi : 10.18632/aging.205253
Enhanced serum levels of tumor necrosis factor-α, interleukin-1β, and -6 in sarcopenia: alleviation through exercise and nutrition intervention
Ke-Vin Chang, Wei-Ting Wu, Yu-Hsin Chen, Lan-Rong Chen, Wei-Hsiang Hsu, Yun-Lian Lin, Der-Sheng Han
doi : 10.18632/aging.205254
The ferroptosis landscape in acute myeloid leukemia
Zhixin Ma, Wenle Ye, Xin Huang, Xia Li, Fenglin Li, Xiangjie Lin, Chao Hu, Jinghan Wang, Jie Jin, Bo Zhu, Jiansong Huang
doi : 10.18632/aging.205257
Crosstalk between copper homeostasis and cuproptosis reveals a lncRNA signature to prognosis prediction, immunotherapy personalization, and agent selection for patients with lung adenocarcinoma
Chao Ma, Zhuoyu Gu, Weizheng Ding, Feng Li, Yang Yang
doi : 10.18632/aging.205281
Long non-coding RNA EGOT is associated with 131iodine sensitivity and contributes to thyroid cancer progression by targeting miR-641/PTEN axis
Ming Wang, Zhengchao Wei, Shuang Wang, Wenjuan Feng, Lihua Shang, Xiaosong Sun
doi : 10.18632/aging.205284
Lnc-PTCHD4-AS inhibits gastric cancer through MSH2-MSH6 dimerization and ATM-p53-p21 activation
Jingyun Wang, Yang Mi, Xiangdong Sun, Xia Xue, Huanjie Zhao, Mengfei Zhang, Baitong Hu, Ihtisham Bukhari, Pengyuan Zheng
doi : 10.18632/aging.205329
