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Different therapies of Chinese herbal medicine for diarrhea-predominant irritable bowel syndrome: A network meta-analysis of double-blinded, placebo-controlled trials
Nian Liu a, Jilei Li b, Yichong Wang b, Shengsheng Zhang
doi : 10.1016/j.jep.2023.116672
Volume 317, 5 December 2023, 116672
Five Tibetan patent medicines orally for ischemic stroke: A systematic review and meta-analysis of randomized controlled trials
Xu-Ran Zhang a,b, Shu-Han Zang a,b, Hong-Xin Zou a,b, Li-Hong Zhu a,b, Ri-Na Sha b, Bo-Wen Liu b, Xing-Lu Dong a,**, Li Zhou
doi : 10.1016/j.jep.2023.116671
Volume 317, 5 December 2023, 116671
Commiphora mukul (Hook. ex Stocks) Engl.: Historical records, application rules, phytochemistry, pharmacology, clinical research, and adverse reaction
Zhuoma Garang a, Qiaoqiao Feng b,c, Rizhun Luo a, Mejia La d, Jingwen Zhang b,c, Lei Wu b,c, Zhang Wang a,b,*, Yongzhong Zeweng a,**, Silang Jiangyong
doi : 10.1016/j.jep.2023.116717
Volume 317, 5 December 2023, 116717
Bioactive components and molecular mechanisms of Salvia miltiorrhiza Bunge in promoting blood circulation to remove blood stasis
Baoyu Wei a, Chengtao Sun a, Haitong Wan a, Qiyang Shou a, Bing Han a, Miaomiao Sheng a, Liqing Li b, Guoyin Kai
doi : 10.1016/j.jep.2023.116697
Volume 317, 5 December 2023, 116697
Adjunctive effect of compound Kushen injection for cancer: An overview of systematic reviews☆
Chenchen Li a, Dong Niu a, Ranpei Zhu a, Xiaoyu Yan a, Haoran Qu a, Yaling Zhang b, Yuling Zheng
doi : 10.1016/j.jep.2023.116778
Volume 317, 5 December 2023, 116778
Chemical constituents, pharmacological action, antitumor application, and toxicity of Strychnine Semen from Strychnons pierriana A.W.Hill.: A review
Weiran Liu , Xintian Tang , Chengyu Fan, Guannan He , Xiaoxin Wang , Xiaodong Liang *, Xia Bao
doi : 10.1016/j.jep.2023.116748
Volume 317, 5 December 2023, 116748
Ethnomedicinal uses, phytochemistry, and pharmacological relevance of Justicia procumbens (Oriental Water Willow) - A promising traditional plant
Sabrin R.M. Ibrahim a,b,*, Shaimaa G.A. Mohamed c, Hossam M. Abdallah d,e, Gamal A. Mohamed
doi : 10.1016/j.jep.2023.116819
Volume 317, 5 December 2023, 116819
Mechanism of action of certain medicinal plants for the treatment of asthma
Kainat Usmani , Subodh Kumar Jain , Shweta Yadav
doi : 10.1016/j.jep.2023.116828
Volume 317, 5 December 2023, 116828
A comprehensive review of vine tea: Origin, research on Materia Medica, phytochemistry and pharmacology
Tiexin Zeng a,b, Yanjun Song a,b, Shunyao Qi a,b, Ruyue Zhang a,b, Lijia Xu a,b,*, Peigen Xiao
doi : 10.1016/j.jep.2023.116788
Volume 317, 5 December 2023, 116788
Glehnia littoralis Fr. Schmidtex Miq.: A systematic review on ethnopharmacology, chemical composition, pharmacology and quality control
Shiyang Li a,b,c,1, Nan Xu a,c,1, Qinqin Fang a,b, Xuemei Cheng a, Jiamei Chen b, Ping Liu b, Li Li c, Changhong Wang a,**, Wei Liu
doi : 10.1016/j.jep.2023.116831
Volume 317, 5 December 2023, 116831
A comprehensive review on Saraca asoca (Fabaceae) - Historical perspective, traditional uses, biological activities, and conservation
Santhosh Kumar J. Urumarudappa a,b, Sachin Rosario c, Ravikanth G d, Suchada Sukrong
doi : 10.1016/j.jep.2023.116861
Volume 317, 5 December 2023, 116861
Anti-bacterial, anti-biofilm and anti-quorum sensing activities of honey: A review
Batool Khataybeh a, Ziad Jaradat b,*, Qutaiba Ababneh b
doi : 10.1016/j.jep.2023.116830
Volume 317, 5 December 2023, 116830
The protective effect of an extract of Salvia miltiorrhiza Bunge (Danshen) on cerebral ischemic injury in animal models: A systematic review and meta-analysis
Xiuzhen Xie a,b, Yingqi Xu c, Xiu Zhou d, Pingping Su b, Xumin Jiang b, Zhuqing Jin
doi : 10.1016/j.jep.2023.116772
Volume 317, 5 December 2023, 116772
Spatholobi caulis: A systematic review of its traditional uses, chemical constituents, biological activities and clinical applications
Yehua Pan , Xiaomin Luo , Puyang Gong
doi : 10.1016/j.jep.2023.116854
Volume 317, 5 December 2023, 116854
Anti-inflammatory effect and component analysis of Chaihu Qingwen granules
Ying Zhou a,*,1, Qing-Xian Li a,b,1, Zheng-Zheng Liao a,1, Yang Liu c, Ying Ouyang a,b, Wen-Jing Jiang a,b, Meng-Ting Tang a,b, Jin-Fang Hu a,**, Wei Zhang
doi : 10.1016/j.jep.2023.116763
Volume 317, 5 December 2023, 116763
Ethnopharmacological basis and pharmacodynamics prospectives for folkloric claims of Rosa webbiana wall. Ex. Royle in diarrhea and asthma via In vitro, In vivo and In silico techniques
Anam Ali , Fatima Saqib
doi : 10.1016/j.jep.2023.116696
Volume 317, 5 December 2023, 116696
Vetiver aerial parts and roots ameliorate rheumatoid arthritis in complete Freund's adjuvant rat model, a phytochemical profiling and mechanistic study
Mahmoud A.M. Arafat a,*, Mohammed N.A. Khalil b, Osama G. Mohamed b,c, Omnia A.M. Abd El- Ghafar d, Ashootosh Tripathi c,e, Engy A. Mahrous b,f, Essam M. Abd El-kader g, Seham El- Hawary
doi : 10.1016/j.jep.2023.116764
Volume 317, 5 December 2023, 116764
Effect of Salvia miltiorrhiza Bunge extracts on improving the efficacy and reducing the toxicity of Tripterygium wilfordii polyglycosides in the treatment of rheumatoid arthritis
Lei Zhang a, Shiqin Jiang a, Zehao Guan a, Junyuan Huang a, Zhaokun Yin a, Guoyao Tan a, Yuanyuan Wang b, Zhongxiang Zhao b, Min Huang a, Jing Jin
doi : 10.1016/j.jep.2023.116782
Volume 317, 5 December 2023, 116782
Clinical efficacy and metabolomics study of Wendan Decoction in the treatment of phlegm-dampness obstructive sleep apnea-hypopnea syndrome with type 2 diabetes mellitus
Sifeng Zhou a,b, Haishu Xu c, Jieyun Zhu d, Xinsheng Fan b,*, Jinming Zhang
doi : 10.1016/j.jep.2023.116775
Volume 317, 5 December 2023, 116775
Liensinine improves AngII-induced vascular remodeling via MAPK/TGF-β1/Smad2/3 signaling
Peizhi Jia a,1, Daxin Chen a,b,c,1, Ying Zhu d,1, Meiling Wang a, Jianwei Zeng a,b,e, Ling Zhang a,b,c, Qiaoyan Cai a,b,c, Dawei Lian a,b,c, Chunyu Zhao a, Yaoyao Xu a, Jianfeng Chu a,b,c, Shan Lin a,b,c,*, Jun Peng a,b,c,f,**, Wei Lin
doi : 10.1016/j.jep.2023.116768
Volume 317, 5 December 2023, 116768
Saponin of Aralia taibaiensis promotes angiogenesis through VEGF/VEGFR2 signaling pathway in cerebral ischemic mice
Xingru Tao a,b,1, Kedi Liu c,1, Weihong Li b,1, Shi Zhao c, Chengzhao Liu b, Qi Dai b, Taiwei Dong b, Peifeng Wei d,****, Jialin Duan e,***, Jingwen Wang a,**, Miaomiao Xi
doi : 10.1016/j.jep.2023.116771
Volume 317, 5 December 2023, 116771
Topical Chinese herbal medicine in treating atopic dermatitis (eczema): A systematic review and meta-analysis with core herbs exploration
Meng-Chun Wang a,1, Yu-Ting Chou b,1, Ming-Chen Kao a,c, Qian-Ying Lin d, Sing-Ya Chang c, Hsing-Yu Chen
doi : 10.1016/j.jep.2023.116790
Volume 317, 5 December 2023, 116790
Buccal spray of standardized Berberis aristata extract causes tumour regression, chemoprotection and downregulation of inflammatory mediators in oral cancer hamster model
Preeti Tamane , Kakasaheb Mahadik , Varsha Pokharkar
doi : 10.1016/j.jep.2023.116732
Volume 317, 5 December 2023, 116732
Total saponins from Panax japonicus attenuate acute alcoholic liver oxidative stress and hepatosteatosis by p62-related Nrf2 pathway and AMPK-ACC/PPARα axis in vivo and in vitro
Ling Qiu a,b, Ruibing Feng a, Qiu-shuang Wu a,c, Jian-bo Wan a,**, Qing-wen Zhang
doi : 10.1016/j.jep.2023.116785
Volume 317, 5 December 2023, 116785
Pi-Pa-Run-Fei-Tang alleviates lung injury by modulating IL-6/JAK2/STAT3/IL-17 and PI3K/AKT/NF-κB signaling pathway and balancing Th17 and Treg in murine model of OVA-induced asthma
Xiao-Lu Jie a,1, Zi-Rui Luo a,1, Jin Yu c, Zhe-Ren Tong a, Qiao-Qiao Li a, Jia-Hui Wu a, Yi Tao a, Pei-Shi Feng a, Ji-Ping Lan b,**, Ping Wang
doi : 10.1016/j.jep.2023.116719
Volume 317, 5 December 2023, 116719
GuiLu-ErXian Glue extract promotes mesenchymal stem cells (MSC)-Induced chondrogenesis via exosomes release and delays aging in the MSC senescence process
Yong-Hong Yang a, Che-Sheng Wen b, Yung-Ling Kuo c, Su-Ling Fu a, Tung-Yi Lin a, Chao-Ming Chen d,e,f, Po-Kuei Wu d,e,f, Wei-Ming Chen d,e, Jir-You Wang
Network pharmacology and metabolomics elucidate the underlying mechanisms of Venenum Bufonis in the treatment of colorectal cancer
Cimin Tao a, Jiao Wang a, Zhilei Gu a, Hongfei Ni a,c, Yingjie Luo a, Jiawei Ling a, Yong Chen a, Yongjiang Wu a, Xuesong Liu a,c, Yuan Zhou b, Tengfei Xu
doi : 10.1016/j.jep.2023.116695
Volume 317, 5 December 2023, 116695
Uncovering the key pharmacodynamic material basis and possible molecular mechanism of extract of Epimedium against liver cancer through a comprehensive investigation
Yi-min Liu a,b,1, Xiao-qi Li a,b,1, Xiao-ran Zhang a,b, Yuan-yuan Chen a,b, Yu-ping Liu a,b, Huang- qin Zhang a,b,**, Yan Chen
doi : 10.1016/j.jep.2023.116765
Volume 317, 5 December 2023, 116765
Chalcone derivatives from licorice inhibit human and rat gonadal 3β-hydroxysteroid dehydrogenases as therapeutic uses
Lei Ye a,b,c,d,f, Ming Su b,c,d,f, Xinyi Qiao a, Shaowei Wang e, Ke Zheng a, Yang Zhu b,c,d, Huitao Li b,c,d, Yiyan Wang b,c,d,**, Ren-shan Ge
doi : 10.1016/j.jep.2023.116690
Volume 317, 5 December 2023, 116690
Effect of microneedle roller on promoting transdermal absorption of crossbow-medicine liquid via transdermal administration of Traditional Chinese Medicine and the safety of crossbow-medicine needle therapy: An experimental study
Hongyan Luo a, Fangfang Zan b, Jin Cui
doi : 10.1016/j.jep.2023.116751
Volume 317, 5 December 2023, 116751
Effects of Artemisia annua L. on postmenopausal syndrome in ovariectomized mice
Do Yeon Kim a, So-Ri Son a, Jae Youn Kim b, Ji Won Min a, Chang Hyeon Kong a, Keontae Park a, Mijin Jeon a, Woo Chang Kang a, Seo Yun Jung a, Jung-Hye Choi a,c, Dae Sik Jang a,**, Jong Hoon Ryu
doi : 10.1016/j.jep.2023.116800
Volume 317, 5 December 2023, 116800
Iristectorigenin C suppresses LPS-induced macrophages activation by regulating mPGES-1 expression and p38/JNK pathway
Xin Guo a,b,1, Yun-Da Yao b,1, Jun-Li Kang b,1, Fu-Kang Luo c,1, Xi-Jun Mu a, Yan-Yu Zhang d, Ming-Tai Chen b,e, Meng-Nan Liu b,f, Chi-Chou Lao b, Zi-Hao Tan c, Yu-Feng Huang a, Ying Xie a,**, You-Hua Xu b,***, Peng Wu c,****, Hua Zhou
doi : 10.1016/j.jep.2023.116706
Volume 317, 5 December 2023, 116706
Exploring the anti-virulence potential of plants used in traditional Mayan medicine to treat bacterial infections
Naybi Mu?noz-C´azares a,1, Maria Claudia Pe?na-Gonz´alez a,1, Israel Castillo-Ju´arez b, Jose Luis D?az-N??nez c, Luis Manuel Pe?na-Rodr?guez
doi : 10.1016/j.jep.2023.116783
Volume 317, 5 December 2023, 116783
Quantitative-HPLC-DAD polyphenols analysis, anxiolytic and cognition enhancing potentials of Sorbaria tomentosa Lindl. Rehder
Mater H. Mahnashi a, Muhammad Ayaz b,*, Yahya S. Alqahtani a, Bandar A. Alyami a, Muhammad Shahid c, Omaish Alqahtani d, Saeed M. Kabrah e, Alam Zeb f, Farhat Ullah b, Abdul Sadiq
doi : 10.1016/j.jep.2023.116786
Volume 317, 5 December 2023, 116786
Astragulus embranaceus (Fisch.) Bge-Dioscorea opposita Thunb herb pair ameliorates sarcopenia in senile type 2 diabetes mellitus through Rab5a/mTOR-mediated mitochondrial dysfunction
Meiling She a,b, Minna Huang a,b, Jing Zhang a, Yan Yan a,b, Lingli Zhou c, Meng Zhang a,b,**, Yajun Yang d,***, Dongtao Wang
doi : 10.1016/j.jep.2023.116737
Volume 317, 5 December 2023, 116737
Mailuoning oral liquid attenuates convalescent cerebral ischemia by inhibiting AMPK/mTOR-associated apoptosis and promoting CREB/BDNF-mediated neuroprotection
Xiaoqiong Liu a,1, Lingling Fan a,1, Jian Li a,b,1, Ziyu Bai a, Yue Wang a, Yafang Liu a, Hong Jiang a, Anhua Tao a, Xiang Li c, Hui Zhang b, Ninghua Tan
The ethanol extract of Scutellaria baicalensis Georgi attenuates complete Freund's adjuvant (CFA)-induced inflammatory pain by suppression of P2X3 receptor
Li Gao a,b,c,*,1, Jin-xia Zhao a,b,c,1, Xue-mei Qin a,b,c, Jing Zhao
doi : 10.1016/j.jep.2023.116762
Volume 317, 5 December 2023, 116762
Treatment of polycystic ovary syndrome and its associated psychiatric symptoms with the Mongolian medicine Nuangong Qiwei Pill and macelignan
Xiao-Jie Shi a, Yang Du a, Lei Chen a, Yuan-Yuan Chen b, Man Luo b,**, Yong Cheng
doi : 10.1016/j.jep.2023.116812
Volume 317, 5 December 2023, 116812
Shenlian extract protected ox-LDL-loaded macrophages against ER stress by promoting LAL-LXRα mediated cholesterol flux
Chun-xia Nie a,b, Xin-ke Du b, Li-na Yang b, Man-jing Li b, Li Liu b, Ying Chen b, Qing Yang b, Xiao-gang Weng b, Wei-yan Cai b, Yu Dong c,**, Xiao-xin Zhu b,*, Qi Li
doi : 10.1016/j.jep.2023.116721
Volume 317, 5 December 2023, 116721
Bioinformatics analysis and in vivo validation study of Ophiocordyceps sinensis (Berk.)G.H.Sungetal against lung adenocarcinoma
Xingfang Zhang a,b, Mengyuan Wang b, Xinxin Liang a, Jianv Wang a, Ming Zhang a,c, Cen Li a,c, Lixin Wei a,c,**, Hongtao Bi
doi : 10.1016/j.jep.2023.116739
Volume 317, 5 December 2023, 116739
Reduction of Th2 inflammation and fibrosis in eosinophilic esophagitis in a murine model by citri reticulatae pericarpium
Mingzhuo Cao a, Zeqian Wang a,b, Yuan Wang a,b, Heyun Jing a, Yijia Meng a,b, Yu Geng b, Xiu-Min Li c,*, Mingsan Miao
doi : 10.1016/j.jep.2023.116767
Volume 317, 5 December 2023, 116767
Assessment of subchronic toxicity and toxicokinetics of AG NPP709 in Sprague-Dawley rats
Soo Im Chang a,b, Doug-Young Ryu
doi : 10.1016/j.jep.2023.116801
Volume 317, 5 December 2023, 116801
The therapeutic effect of wasp venom (Vespa magnifica, Smith) and its effective part on rheumatoid arthritis fibroblast-like synoviocytes through modulating inflammation, redox homeostasis and ferroptosis
Lian-Li Ni a,c,1, Yi-Hao Che a,e,f,1, Hong-Mei Sun a,1, Bo Wang d, Mei-Yu Wang b, Zi-Zhong Yang a, Heng Liu a, Huai Xiao a, Da-Song Yang a, Hui-Lin Zhu b,**, Zhi-Bin Yang
doi : 10.1016/j.jep.2023.116700
Volume 317, 5 December 2023, 116700
Isolation of alkaloidal and glycosidal fractions from leaves of Trigonella foenum-graecum L. cv. Desi indigenous to Pakistan for antiprostaglandin evaluation as substitute of nonsteroidal anti-inflammatory drugs
Tahir Mahmood Shaukat a,*,1, Muhammad Ovais Omer a,**,1, Aqeel Javeed a, Habib ur Rehman b, Tariq Mahmood Shaukat
doi : 10.1016/j.jep.2023.116730
Volume 317, 5 December 2023, 116730
Liangxue Jiedu formula improves imiquimod-induced psoriasiform dermatitis with circadian desynchrony by regulating Th17Â cell differentiation based on network pharmacological analysis
Xinran Xie a,b,*, Lei Zhang a,b, Yan Lin a,b, Xin Liu a,b, Xuyang Han a,b, Ping Li
doi : 10.1016/j.jep.2023.116807
Volume 317, 5 December 2023, 116807
Icariside â…¡ attenuates bleomycin-induced pulmonary fibrosis by modulating macrophage polarization
Lingling Deng a,b,1, Boshu Ouyang a,b,1, Hanlin Shi a,b, Fangyong Yang a,b, Shihuan Li a,b, Cong Xie a,b, Wenjing Du a,b, Lingli Hu a,b, Ying Wei a,b,**, Jingcheng Dong
doi : 10.1016/j.jep.2023.116810
Volume 317, 5 December 2023, 116810
Fufang Zhenzhu Tiaozhi (FTZ) capsule ameliorates diabetes-accelerated atherosclerosis via suppressing YTHDF2-mediated m6A modification of SIRT3 mRNA
Yue Zhang a,1, Ruonan Wang a,1, Huiling Tan a,1, Kaili Wu a, Yaju Hu a, Hongtao Diao a, Dongwei Wang a, Xinyuan Tang a, Mingyang Leng a, Xu Li a, Zhenlu Cai a, Duosheng Luo a, Xiaoqi Shao a, Meiling Yan a, Yingyu Chen a,b, Xianglu Rong a, Jiao Guo
doi : 10.1016/j.jep.2023.116766
Volume 317, 5 December 2023, 116766
Ipomoea pes-tigridis L. extract accelerates wound healing in Wistar albino rats in excision and incision models
Gayathri Nataraj a, Gayathri Jagadeesan a,b, Ashwini Lydia Manoharan a, Kasipandi Muniyandi a,c, Saikumar Sathyanarayanan d, Parimelazhagan Thangaraj
doi : 10.1016/j.jep.2023.116808
Volume 317, 5 December 2023, 116808
Identification of paeoniflorin from Paeonia lactiflora pall. As an inhibitor of tryptophan 2,3-dioxygenase and assessment of its pharmacological effects on depressive mice
Xiaoxia Liang a,b,1, Ting Su a,1, Pingzhou Wu a, Yanting Dai a, Yanmin Chen a, QiQi Wang a, Cheng Cao a, Fenglian Chen a, Qing Wang a, Shuling Wang
doi : 10.1016/j.jep.2023.116714
Volume 317, 5 December 2023, 116714
Shaoyao Gancao decoction alleviates the central hyperalgesia of recurrent NTG-induced migraine in rats by regulating the NGF/TRPV1/COX-2 signal pathway
Yamin Luo c, Yuehua Qiu a, Ranran Zhou a, Yao Zhang a, Xuenian Ji a, Zijian Liu a, Ran Li a, Yi Zhang a, Feng Yang a, Jianchen Hou a, Shujing Zhang a, Tieshan Wang c, Haochong Song d, Xiaohua Tao
doi : 10.1016/j.jep.2023.116781
Volume 317, 5 December 2023, 116781
Anti-obesity effect of Lythri herba water extracts in vitro and in vivo
Yea-Jin Park a,b, Hee-Young Kim b,c, Su Shin d, JungHyun Lee d, In Heo e,f, Yun-Yeop Cha a, Hyo-Jin An
doi : 10.1016/j.jep.2023.116789
Volume 317, 5 December 2023, 116789
Ramulus Cinnamomi essential oil exerts an anti-inflammatory effect on RAW264.7Â cells through N-acylethanolamine acid amidase inhibition
Wei Jia a,b,1, Xiwen He a,1, Wenhui Jin a, Jinping Gu c, Siyu Yu a,b, Jianlin He a, Zhiwei Yi a, Bing Cai a, Huiyuan Gao b, Longhe Yang
doi : 10.1016/j.jep.2023.116747
Volume 317, 5 December 2023, 116747
Digeda-4 decoction and its disassembled prescriptions improve dyslipidemia and apoptosis by regulating AMPK/SIRT1 pathway on tyloxapol-induced nonalcoholic fatty liver disease in mice
Xiaoping Ji a,c,d,1, Qianqian Ma c,d,1, Xuan Wang c,d, Hui Ming c,d, Guihua Bao a,d, Minghai Fu b,*, Chengxi Wei
Qinzhu Liangxue inhibits IL-6-induced hyperproliferation and inflammation in HaCaT cells by regulating METTL14/SOCS3/STAT3 axis
Yiran Chen a, Xiao Miao a,b, Yanwei Xiang c,d, Le Kuai a, Xiaojie Ding a, Tian Ma a, Bin Li a,e,**, Bin Fan
doi : 10.1016/j.jep.2023.116809
Volume 317, 5 December 2023, 116809
N6-methyladenosine profiling reveals that Xuefu Zhuyu decoction upregulates METTL14 and BDNF in a rat model of traumatic brain injury
Dandan Feng a,b, Pengfei Li c, Wei Xiao a,b, Zhuan Pei a,b, Peishun Chen a,b, Mingrui Hu a,b, Zhaoyu Yang a,b, Teng Li a,b, Zian Xia a,b, Hanjin Cui a,b, Haigang Li d, Qing Huang b,e, Wei Zhang f, Tao Tang a,b, Yang Wang a,b,
doi : 10.1016/j.jep.2023.116823
Volume 317, 5 December 2023, 116823
Induction of S arrest and apoptosis in human oral cancer cells by Rhinacanthin-C extracted from Rhinacanthus nasutus via modulating Akt and p38 signaling pathways
Sirinthip Klaophimai a, Phisit Pouyfung b,**, Ariyaphong Wongnoppavich c, Kongthawat Chairatvit
doi : 10.1016/j.jep.2023.116813
Volume 317, 5 December 2023, 116813
Comparative pharmacokinetics of six bioactive components of Shen-Wu-Yi-Shen tablets in normal and chronic renal failure rats based on UPLC-TSQ-MS/MS
Yudan Mei a,1, Xiaoyu Tong b,c,1, Yumei Hu b,c, Wenjun Liu b,c, Jiajia Wang b,c, Kaihong Lv d, Xu Li b,c, Liang Cao b,c, Zhenzhong Wang b,c, Wei Xiao a,b,c,*, Xia Gao
doi : 10.1016/j.jep.2023.116818
Volume 317, 5 December 2023, 116818
Cynanchum komarovii extract for the treatment of rheumatoid arthritis by acting on synovial cells in vitro and in vivo
Fusheng Hao a,c, Li Tao a, Junmei Liu b, Yan Ma a, Jin Zhang a, Wen Wang a, Wei Yan a, Bo Wang a, Xiaofei Wang a, Xingyi Chen a, Yingying Ma a, Hongli Fan a, Xi Zhao a, Zhizhong Wang a,c,**, Changcai Bai
doi : 10.1016/j.jep.2023.116825
Volume 317, 5 December 2023, 116825
Exploring the mechanism of Jianpi Huatan recipe in protecting hepatocellular carcinoma based on network pharmacology
Caiyun Zhang a,b, Hongjiao Xiang b, Junmin Wang b, Gaoxuan Shao a, Peilun Ding b, Ying Gao b, Hanchen Xu a, Guang Ji a,**, Tao Wu
doi : 10.1016/j.jep.2023.116676
Volume 317, 5 December 2023, 116676
Ameliorating effect of polyherbal formulation (Febrojith) on acute and chronic inflammatory model via inhibiting inflammation and oxidative stress
M. Ratheesh a,*, Svenia P. Jose a, S. Sheethal a, A. Sindhu b, S. Sandya c, Aditya Asish
doi : 10.1016/j.jep.2023.116824
Volume 317, 5 December 2023, 116824
Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis
Jingwen Xu a,b, Zhenhua Tian b, Zhe Li a, Xiaoshi Du b, Yansong Cui c, Jiangrong Wang a, Mei Gao a,b,**, Yinglong Hou
doi : 10.1016/j.jep.2023.116675
Volume 317, 5 December 2023, 116675
Pharmacokinetic evaluation of Sinisan containing vinegar-processed products in depressive rats, a comprehensive perspective of ‘individual herb, herb-pair, and herbal formula’
Hui Zhu a,b,1, Yating Zhang a,b,1, Yu Duan a,b,1, Ke Pei c, Sicong Tu d, Yijing Chen a,b, Hao Cai
doi : 10.1016/j.jep.2023.116817
Volume 317, 5 December 2023, 116817
Phytochemical analysis of Origanum majorana L. extract and investigation of its antioxidant, anti-inflammatory and immunomodulatory effects against experimentally induced colitis downregulating Th17 cells.
Medhat Taha a,b,*, Sara T. Elazab c, Omer Abdelbagi d, Abdullah A. Saati e, Omar Babateen f, Tourki A.S. Baokbah g, Naeem F. Qusty h, Mohamed Ezzat Mahmoud i, Mohie Mahmoud Ibrahim a, Alaa M. Badawy
doi : 10.1016/j.jep.2023.116826
Volume 317, 5 December 2023, 116826
Salvianolic acids from Salvia miltiorrhiza Bunge and their anti-inflammatory effects through the activation of α7nAchR signaling
Li-fang Zou a,1, Di-fa Liu b,c,1, Hua Yang a,1, Chun-hong Zhou a, Shuang-bing Deng c, Ni-shan Xu a, Xue-mei He a, Yao-qi Liu c, Meng Shao a,**, Lin-zhong Yu a,d,***, Jun-shan Liu
doi : 10.1016/j.jep.2023.116743
Volume 317, 5 December 2023, 116743
Centella asiatica alleviates psoriasis through JAK/STAT3-mediated inflammation: An in vitro and in vivo study
Pei Lin 1, Hong-yu Shi 1, Yin-ying Lu, Jun Lin
doi : 10.1016/j.jep.2023.116746
Volume 317, 5 December 2023, 116746
Discovery of effective combination from Renshen-Fuzi herbal pair against heart failure by spectrum-effect relationship analysis and zebrafish models
Chu-Jun Li 1, Rong-Rong Zhai 1, Xiao-Yu Zhu , Zi-Fan Guo , Hua Yang
doi : 10.1016/j.jep.2023.116832
Volume 317, 5 December 2023, 116832
Research into the anti-pulmonary fibrosis mechanism of Renshen Pingfei formula based on network pharmacology, metabolomics, and verification of AMPK/PPAR-γ pathway of active ingredients
Lu Yan a,b,1, Min-Yue Jiang a,1, Xin-Sheng Fan
doi : 10.1016/j.jep.2023.116773
Volume 317, 5 December 2023, 116773
The antihyperuricemia activity of Astragali Radix through regulating the expression of uric acid transporters via PI3K/Akt signalling pathway
Meng-Qi Zhang a,1, Ke-Xin Sun b,1, Xu Guo a, Ying-Ying Chen a, Cai-Yun Feng a, Jia-Shu Chen a, Joao C.M. Barreira c, Miguel A. Prieto d, Jin-Yue Sun a,*, Jian-Dong Zhang e,**, Ning-Yang Li f,***, Chao Liu
doi : 10.1016/j.jep.2023.116770
Volume 317, 5 December 2023, 116770
Erchen Decoction alleviates obesity-related hepatic steatosis via modulating gut microbiota-drived butyric acid contents and promoting fatty acid β-oxidation
Ling Zhang a,1, Ning Chen a,1, Libin Zhan b,c,d,*, Tingting Bi a, Wen Zhou a, Lijing Zhang a, Lianlian Zhu
doi : 10.1016/j.jep.2023.116811
Volume 317, 5 December 2023, 116811
Jieduquyuziyin prescription enhances CD11a and CD70 DNA methylation of CD4+ T cells via miR-29b-sp1/DNMT1 pathway in MRL/lpr mice
Shuo Huang a,1, Jiaqi Peng a,1, Yihong Gan a,1, Leiming Chen c, Zhengyang Zhu d, Fengyuan Tian a, Lina Ji e, Yongsheng Fan a, Chuanlong Zhou b,**, Jie Bao
doi : 10.1016/j.jep.2023.116776
Volume 317, 5 December 2023, 116776
Tiaogan Jiejiu Tongluo Formula attenuated alcohol-induced chronic liver injury by regulating lipid metabolism in rats
Chunqiu Fang a,1, Jingzhou Zhang b,1, Jiajun Han a, Yuting Lei a, Zhanhong Cao c, Jianheng Pan a, Zhi Pan c, Zhong Zhang c, Ning Qu b, Haoming Luo a,***, Yan Ma d,**, Dong Han
doi : 10.1016/j.jep.2023.116838
Volume 317, 5 December 2023, 116838
Modulatory properties of Thespesia garckeana (F. Hoffm.) Exell & Hillc. Aqueous fruit extract on female rats reproductive hormones and tissues histology and potential inhibitory activity of its constituents against SRD5α2
Babasoji Percy Omoniwa a,b,*, Jamiu Oyewole Omirinde c, Adam Moyosore Afodun d, Charles Obiora Nwonuma a, Omolola Soji-Omoniwa e, Rhoda Nyamshak Dinmung b, Thaddeus Terdoo Abwa b, Isreal Shilly Dimka b, Godfrey Patrick Abimiku b, Joy Oluchi Boniface b, Valentina Bangs Victor
doi : 10.1016/j.jep.2023.116842
Volume 317, 5 December 2023, 116842
Medicinal plants traditionally used in the health care practices by the indigenous communities of the Trans-Himalayan region of Ladakh, India
Zohra Batool a,b, Kanwaljeet Singh a, Sumeet Gairola
doi : 10.1016/j.jep.2023.116837
Volume 317, 5 December 2023, 116837
Volatile profiling coupled with multivariate analysis, antiproliferative and anti-inflammatory activities of rhizome essential oil of four Hedychium species from India
Swagat Mohanty , Asit Ray , Chiranjibi Sahoo , Ambika Sahoo , Sudipta Jena , Pratap Chandra Panda , Sanghamitra Nayak
doi : 10.1016/j.jep.2023.116835
Volume 317, 5 December 2023, 116835
Potential natural antimicrobial and antibiofilm properties of Piper betle L. against Staphylococcus pseudintermedius and methicillin-resistant strains
Pavarish Jantorn a, Varomyalin Tipmanee b, Warapond Wanna a, Nuvee Prapasarakul c, Monton Visutthi d, Dennapa Saeloh Sotthibandhu
doi : 10.1016/j.jep.2023.116820
Volume 317, 5 December 2023, 116820
Shizhifang ameliorates pyroptosis of renal tubular epithelial cells in hyperuricemia through inhibiting NLRP3 inflammasome
Jiabao Zhou a,b,c,d, Chuanxu Wang a,b,c,d, Xuming Zhang a,b,c,d, Zhiyuan Wu a,b,c,d, Yansheng Wu a,b,c,d, Dongdong Li a,b,c,d, Jiandong Gao
doi : 10.1016/j.jep.2023.116777
Volume 317, 5 December 2023, 116777
Qingjin Huatan decoction protects mice against influenza a virus pneumonia via the chemokine signaling pathways
Miaomiao Liu a,b, Fangshu Zhao a, Jinke Xu c, Xiaojing Zhu a, Yangang Zhao b, Rou Wen a, Varada Anirudhan d, Lijun Rong d,**, Jingzhen Tian a,b,***, Qinghua Cui
doi : 10.1016/j.jep.2023.116745
Volume 317, 5 December 2023, 116745
Correlations of kratom (Mitragyna speciosa Korth.) tea bag preparations and reported pharmacological effects
Oliver Grundmann a,b,*, Katherine Hill c, Everest Al Barzanji b, Nilofar Ghulam Hazrat b, Gurnoor Kaur b, Ryan Einstein Negeve b, Soren Shade d, Sam Weber d, Charles A. Veltri
doi : 10.1016/j.jep.2023.116779
Volume 317, 5 December 2023, 116779
Mechanisms of Si-Wu Decoction in the treatment of ulcerative colitis revealed by network pharmacology and experimental verification
Lin Wang a,1, Ya Liu a,1, Guiyan Shen a, Guanlin He a, Shoutao Qiu b,**, Baojie Li
doi : 10.1016/j.jep.2023.116847
Volume 317, 5 December 2023, 116847
Study on the mechanism of Orthosiphon aristatus (Blume) Miq. in the treatment of hyperuricemia by microbiome combined with metabonomics
Chunsheng Zhu a,1, Hongjuan Niu b,1, Meng Bian a, Xiaochuan Zhang a, Xiaomeng Zhang c,*, Zheng Zhou
doi : 10.1016/j.jep.2023.116805
Volume 317, 5 December 2023, 116805
Traditional Chinese medicine Kuan-Sin-Yin decoction inhibits cell mobility via downregulation of CCL2, CEACAM1 and PIK3R3 in hepatocellular carcinoma cells
Chueh-Tan Chen a, Chian-Feng Chen b, Tung-Yi Lin a,c, Wei-Jyun Hua a,c, Kate Hua b, Ching-Yao Tsai d,e,f,g,**, Chung-Hua Hsu
doi : 10.1016/j.jep.2023.116834
Volume 317, 5 December 2023, 116834
Ginger (Zingiber officinale Roscoe) preparations for prophylaxis of postoperative nausea and vomiting: A Bayesian network meta-analysis
Chunyang Zhao a,b, Weiyuan Chen b, Daqiu Wang c, Xiufeng Cong d, Min Zhu e, Chengrui Zhu f, Jiayao Xu g, Jiayi Cai
doi : 10.1016/j.jep.2023.116791
Volume 317, 5 December 2023, 116791
Marmesin isolated from Celtis durandii Engl. root bioactive fraction inhibits β-hematin formation and contributes to antiplasmodial activity
Ifeoma C. Ezenyi a,*, Jersley D. Chirawurah b, Nekpen Erhunse c,d, Prakhar Agrawal c, Dinkar Sahal c, John O. Igoli
doi : 10.1016/j.jep.2023.116804
Volume 317, 5 December 2023, 116804
Tenuigenin activates the IRS1/Akt/mTOR signaling by blocking PTPN1 to inhibit autophagy and improve locomotor recovery in spinal cord injury
Li’e Zang a, Dewang Fu b,*, Fan Zhang a, Ning Li a, Xue Ma
doi : 10.1016/j.jep.2023.116841
Volume 317, 5 December 2023, 116841
Yi-Qi-Jian-Pi formula inhibits hepatocyte pyroptosis through the IDH2-driven tricarboxylic acid cycle to reduce liver injury in acute-on-chronic liver failure
Rong Zhao a,b,1, Qiang Zhao a,b,1, Xi Wang a,b,1, Xiaomei Chen a, Chongfeng Liang a, Qian Xiao a, Shiyan Yang a, Shanzhong Tan
doi : 10.1016/j.jep.2023.116683
Volume 317, 5 December 2023, 116683
Advantage effect of Dalbergia pinnata on wound healing and scar formation of burns
Zhuoyue Song a,b,1, Tian Yu b,1, Chengcheng Ge c,1, Xiuting Shen d, Pan Li d, Jinchuan Wu a, Chunzhi Tang b, Tao Liu b, Danyan Zhang d,**, Shijie Li
Identification of the therapeutic effect and molecular mechanism of Coptis chinensis Franch. and Magnolia officinalis var. biloba on chronic gastritis
Jin Song a,b, Xiaolong Xu a,b, Shasha He a,b, Huicun Zhang a,b, Ning Wang a,b, Yunjing Bai a,b, Bo Li a,b,*, Shengsheng Zhang
doi : 10.1016/j.jep.2023.116864
Volume 317, 5 December 2023, 116864
Tou Nong powder obstructs ulcerative colitis through the regulation of NF-κB/NLRP3/Caspase-1/GSDMD inflammasome pyroptotic pathway
Zhen Ye a,1, Linzhen Li a,1, Yuzheng Li a, Yu Hu a, Mingquan Wu b, Han Yu a, Qian Zhao a, Chen Zhang c, Fating Lu a, Xi Peng d, Mengmeng Sun e, Kumar Ganesan f, Kaihua Qin g,**, Qiaobo Ye
doi : 10.1016/j.jep.2023.116846
Volume 317, 5 December 2023, 116846
Chemical composition, antinociceptive and anti-inflammatory activities of the curzerene type essential oil of Eugenia uniflora from Brazil
Ellen Nayara Silva de Jesus a,b, Mateus Silva Tavares b, Pedro An?bal C. Barros b, Daniele Carvalho Miller b,c, Pedro Iuri C. da Silva b,d, Jofre Jacob S. Freitas b, Anderson B. de Lima b, William N. Setzer e, Joyce Kelly R. da Silva d,e, Pablo Luis B. Figueiredo a
doi : 10.1016/j.jep.2023.116859
Volume 317, 5 December 2023, 116859
Anti-inflammatory effects of Allium cepa L. peel extracts via inhibition of JAK-STAT pathway in LPS-stimulated RAW264.7 cells
Hyun-Seung Lee a,b,1, Yong-Jin Kwon a,c, Eun-Bi Seo a,b, Seul-Ki Kim a, Haeri Lee a,d, Jin-Tae Lee c, Pahn-Shick Chang e, Young Jin Choi e, Sung-Hyen Lee f, Sang-Kyu Ye
Antinociceptive and anti-inflammatory activities of essential oil of the leaves of Amburana cearensis (Allemão) A.C. Smith. from the semi-arid region of Northeastern Brazil
Bruno Oliveira de Veras a,b,c,*, Geovanna Maria de Medeiros Moura d, Amanda Vieira de Barros c, M´arcia Vanusa da Silva c, Priscilla Anne Castro de Assis e, J?lio C´esar Ribeiro de Oliveira Farias de Aguiar f, Daniela Maria do Amaral Ferraz Navarro f, Rafael Matos Ximenes b, Almir Gonçalves Wanderley g, Maria Betˆania Melo de Oliveira c, Ana Catarina de Sousa Lopes
doi : 10.1016/j.jep.2023.116858
Volume 317, 5 December 2023, 116858
Integration of metabolomics and network pharmacology to reveal the protective mechanism underlying Wogonoside in acute myocardial ischemia rats
Wenzhong Feng a, Cancan Duan b, Fuzhu Pan a, Caiying Yan a, Hongjing Dong c, Xiao Wang c,*, Jianyong Zhang
doi : 10.1016/j.jep.2023.116871
Volume 317, 5 December 2023, 116871
Therapeutic effects of Siegesbeckia orientalis L. and its active compound luteolin in rheumatoid arthritis: network pharmacology, molecular docking and experimental validation
Bixia Xiao a,1, Junmao Li b,1, Zhiping Qiao a, Songhong Yang b, Hiu-Yee Kwan c,d, Ting Jiang a, Mi Zhang a, Quan Xia a,**, Zhongqiu Liu a,***, Tao Su a,
doi : 10.1016/j.jep.2023.116852
Volume 317, 5 December 2023, 116852
Ling-Gui-Qi-Hua formula alleviates left ventricular myocardial fibrosis in rats with heart failure with preserved ejection fraction by blocking the transforming growth factor-β1 /Smads signaling pathway
Yujiao Shi a,1, Chunqiu Liu a,1, Shuang Xiong a,1, Ling Yang b, Chenguang Yang a, Wenbo Qiao a, Yongcheng Liu a, Siyu Liu a, Jiangang Liu b,**, Guoju Dong
doi : 10.1016/j.jep.2023.116849
Volume 317, 5 December 2023, 116849
Study on the material basis and action mechanisms of sophora davidii (Franch.) skeels flower extract in the treatment of non-small cell lung cancer
Baibai Ye a, Ping Chen a, Cheng Lin a, Chenning Zhang b,*, Linfu Li
doi : 10.1016/j.jep.2023.116815
Volume 317, 5 December 2023, 116815
Dissection of scientific compatibility of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia from the perspective of toxicology
Zhenhong Jiang a,1, Yuting Sun b,c,1, Zhenhui Wu c,d, Mingxia Tang d, Anping Ye c,d, Bodan Tu c,d, Jianfeng Yi e,**, Huanhua Xu c,d,*, Yue Gao
doi : 10.1016/j.jep.2023.116895
Volume 317, 5 December 2023, 116895
Exploring the pharmacological mechanisms and key active ingredients of total flavonoids from Lamiophlomis rotata (Benth.) Kudo against rheumatoid arthritis based on multi-technology integrated network pharmacology
Hupo Zhan a,1, Ruixin Chen b,1, Mei Zhong c, Guowei Wang a, Guihua Jiang b, Xingbao Tao d, Min Chen a,**, Yunbin Jiang
doi : 10.1016/j.jep.2023.116850
Volume 317, 5 December 2023, 116850
Based on network pharmacology to explore the effect and mechanism of Yipibushen decoction in improving obese type 2 diabetes mellitus with oligoasthenotspermia
Guangyong Li a,b,1, Qiangqiang Wang a,c,1, Xiaojiang Chen a,1, Puguang Yu a,b,1, Qingjie Peng a, Hua Chen b, Shuai Ren a,b, Chunhong Wang a,c, Yashan Su a, Xiaoxia Liang a,c, Miao Sun a, Xiaoli Du a,c,2,**, Rui He
doi : 10.1016/j.jep.2023.116738
Volume 317, 5 December 2023, 116738
Natural product-derived therapies for treating drug-resistant epilepsies: From ethnopharmacology to evidence-based medicine
Soura Challal a,b,1, Adrianna Skiba c,1, M´elanie Langlois d,2, Camila V. Esguerra e, Jean-Luc Wolfender a,b, Alexander D. Crawford f,g, Krystyna Skalicka-Wo´zniak
doi : 10.1016/j.jep.2023.116740
Volume 317, 5 December 2023, 116740
Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction
Hang Chu a,1, Weitao Zhang a,1, Yan Tan b,1, Zhipeng Diao a,1, Peng Li b, Yapeng Wu a, Like Xie a, Jianguo Sun a, Ke Yang b, Pingping Li c,d, Cen Xie e, Ping Li a, Qian Hua b,**, Xiaojun Xu
doi : 10.1016/j.jep.2023.116665
Volume 317, 5 December 2023, 116665
