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Xihuang pill in the treatment of cancer: TCM theories, pharmacological activities, chemical compounds and clinical applications
Hong-Bin Xu a,b,1,*, Xian-Zhen Chen c,1, Xia Wang d,1, Jing Pan b, Zhao Yi-zhuo a, Chen-Hui Zhou
doi : 10.1016/j.jep.2023.116699
Volume 316, 15 November 2023, 116699
The application of arsenic trioxide in cancer: An umbrella review of meta-analyses based on randomized controlled trials
Jixin Chen a,b, Shuqi Chen c, Huiyan Luo d, Wanyin Wu b,*, Sumei Wang
doi : 10.1016/j.jep.2023.116734
Volume 316, 15 November 2023, 116734
Pharmacokinetics and tissue distribution of 12 major active components in normal and chronic gastritis rats after oral administration of Weikangling capsules
Feng Liu a, Xiaojing Nong a, Wenhua Qu b, Xiaobo Li
doi : 10.1016/j.jep.2023.116722
Volume 316, 15 November 2023, 116722
BSHXF-medicated serum combined with ADSCs regulates the TGF-β1/Smad pathway to repair oxidatively damaged NPCs and its component analysis
Jiahao Duan a,b, Zhaoyong Li b, Enxu Liu a,b, Hongping Long b, Long Chen b,**, Shaofeng Yang
doi : 10.1016/j.jep.2023.116692
Volume 316, 15 November 2023, 116692
Exploring the potential targets of Biling Weitong Granules on visceral hypersensitivity through integration of network pharmacology and in vivo analysis
Qidi Yang 1, Yizhou Zhao 1, Xiangyu Zhao 1, Sishen Sun , Yifei Chen , Jiayin Chen , Duowu Zou *, Ling Zhang
doi : 10.1016/j.jep.2023.116701
Volume 316, 15 November 2023, 116701
Tanshinone IIA mediates protection from diabetes kidney disease by inhibiting oxidative stress induced pyroptosis
Qi Wu c,1, Yu-bo Guan a,b,1, Ke-jia Zhang a, Li Li a,**, Yao Zhou
doi : 10.1016/j.jep.2023.116667
Volume 316, 15 November 2023, 116667
The total alkaloids of Sophora alopecuroides L. improve depression-like behavior in mice via BDNF-mediated AKT/mTOR signaling pathway
Jingyi Li a,1, Ming Zhang c,1, Yiying Pei a, Qifang Yang a, Lihua Zheng a, Guannan Wang a, Ying Sun a, Wei Yang b,**, Lei Liu
doi : 10.1016/j.jep.2023.116723
Volume 316, 15 November 2023, 116723
Therapeutic effects of columbianadin from Angelicae Pubescentis radix on the progression of collagen-induced rheumatoid arthritis by regulating inflammation and oxidative stress
10.1016/j.jep.2023.116727
doi : 10.1016/j.jep.2023.116727
Volume 316, 15 November 2023, 116727
Deciphering anti–benign prostatic hyperplasia potential of liangwanoside II based on metabolite profile characterization combined with targeted network pharmacology
Li Fan a,b,1, Ying Peng a,1, Chongzhi Sun a, Ping Ma a, Chongsheng Peng a, An Sun a, Xiaobo Li
doi : 10.1016/j.jep.2023.116725
Volume 316, 15 November 2023, 116725
Transcriptomics and systems network-based molecular mechanism of herbal formula Huosu-Yangwei inhibited gastric cancer in vivo
Mengyuan Zhang a,1, Yujie Ding b,1, Sheng Hu c, Fulong Li a, Yi Wang a, Yue Zhou a, Mei Qi a, HongMei Ni b,***, Shengquan Fang a,**, Qilong Chen
doi : 10.1016/j.jep.2023.116674
Volume 316, 15 November 2023, 116674
Salvia mitiorrhiza Bunge aqueous extract attenuates infiltration of tumor-associated macrophages and potentiates anti-PD-L1 immunotherapy in colorectal cancer through modulating Cox2/PGE2 cascade
Mengyao Song a,b,1, Cheng Qian a,b,1, Teng Zhang a,b, Yu Tang a,b, Yueke Zhou a,b, Zhonghong Wei a,b, Aiyun Wang a,b, Chongjin Zhong a,c, Yang Zhao a,c,*, Yin Lu
doi : 10.1016/j.jep.2023.116735
Volume 316, 15 November 2023, 116735
Porcine cardiac blood - Salvia miltiorrhiza root alleviates cerebral ischemia reperfusion injury by inhibiting oxidative stress induced apoptosis through PI3K/AKT/Bcl-2/Bax signaling pathway
Shikang Zhou a,b, Xiaoqin Gao b, Can Chen b, Jinyun Zhang a, Yi Zhang b,***, Li Zhang b,*, Xiaojing Yan
doi : 10.1016/j.jep.2023.116698
Volume 316, 15 November 2023, 116698
Integrated network pharmacology and gut microbiome analysis to reveal the mechanism of Qu-Zhuo-Tong-Bi decoction against hyperuricemia and gout
Siyue Song a,1, Moqi Fan a,1, Xianghui Wen a, Xiaowei Shi a, Yu Lou a, Zhixing He a,b, Chengping Wen a,b,**, Tiejuan Shao
doi : 10.1016/j.jep.2023.116736
Volume 316, 15 November 2023, 116736
Insulin sensitization by Feronia elephantum in fructose-induced hyperinsulinemic rats: Insights from computational and experimental pharmacology
Prarambh S.R. Dwivedi a,*, V.P. Rasal a,b,***, Rajashekar S. Chavan a, Pukar Khanal a,**, Vishakha Parab Gaonkar
doi : 10.1016/j.jep.2023.116686
Volume 316, 15 November 2023, 116686
Extracts of Oldenlandia diffusa protects chondrocytes via inhibiting apoptosis and associated inflammatory response in osteoarthritis
Chao Lou a,b, Chihao Lin a,b, Weidan Wang a,b, Hongyi Jiang a,b, Tingwen Cai a,b, Shida Lin a,b, Xinghe Xue a, Jian Lin a,**, Xiaoyun Pan
doi : 10.1016/j.jep.2023.116744
Volume 316, 15 November 2023, 116744
Cod (Gadus) skin collagen peptide powder reduces inflammation, restores mucosal barrier function, and inhibits fibrosis in dextran sodium sulfate-induced colitis in mice
Xiangyu Guo a,1, Xiangdan Li a,1, Yanru Dong a, Wei Xie b, Toufeng Jin c, Dongyuan Xu a,*, Lan Liu
doi : 10.1016/j.jep.2023.116728
Volume 316, 15 November 2023, 116728
Shexiang Tongxin Dropping Pill alleviates M1 macrophage polarization-induced inflammation and endothelial dysfunction to reduce coronary microvascular dysfunction via the Dectin-1/Syk/IRF5 pathway
Lingwen Cui a,1, Yizhou Liu b,1, Yueyao Hu b, Jianteng Dong b, Qiong Deng b, Boyang Jiao b, Ying Sun b, Yan Wu b, Tianhua Liu b,*, Wei Wang b,c,d,**, Chun Li
doi : 10.1016/j.jep.2023.116742
Volume 316, 15 November 2023, 116742
Gracillin relieves pulmonary fibrosis by suppressing the STAT3 axis
Mengyao Xie a,1, Lehe Yang a,1, Jiayun Cheng b, Hongyan Qu c, Yanting Gu a, Cheng Ding a, Xiaomei Xu a, Chengguang Zhao c, Xiaoying Huang a,**, Liangxing Wang
doi : 10.1016/j.jep.2023.116704
Volume 316, 15 November 2023, 116704
Network pharmacology-based approach uncovers the pharmacodynamic components and mechanism of Fructus Tribuli for improving endothelial dysfunction in hypertension
Shu-Yue Wang a,b, Xiao-Chen Sun a,c, Xi-Yu Lv a, Jing-Na Li a, Bing Han a, Kun-Lin Liu a, Shuai Wang a, Hua-Gang Sheng a, Chao Zhang a,*, Fei Guo d,**, Yi-Dong Cui
doi : 10.1016/j.jep.2023.116749
Volume 316, 15 November 2023, 116749
Effects of Danggui-Shaoyao-San on central neuroendocrine and pharmacokinetics in female ovariectomized rats
Fu-Gang Wang a,1, Yi Sun a,1, Juan Cao a, Xu-Ri Shen a, Fu-Wang Liu a, Shuang-Shuang Song a, Xue-Qin Hou a,*, Lei Yin
doi : 10.1016/j.jep.2023.116609
Volume 316, 15 November 2023, 116609
Shenqi formula delayed Alzheimer’s disease-like symptoms by skn-1 pathway in Caernorhabditis elegans
Dejuan Zhi a,b,1, Shuaishuai Xu a,1, Ling Zhang a, Yuxuan Li a, Hai Zhu a, Chengmu Zhao a, Dongsheng Wang
doi : 10.1016/j.jep.2023.116741
Volume 316, 15 November 2023, 116741
Jiawei Yanghe Decoction suppresses breast cancer by regulating immune responses via JAK2/STAT3 signaling pathway
Yanting You a,b,c,1, Xiaomei Chen b,1, Xiaohu Chen b,1, Hong Li a,b,d, Ruisi Zhou b, Jie Zhou b, Meilin Chen b, Baizhao Peng b, Shuai Ji b, Hiu Yee Kwan e, Lifang Zou b, Jingtao Yu b, Yanyan Liu b,**, Yifen Wu c,***, Xiaoshan Zhao
doi : 10.1016/j.jep.2023.116358
Volume 316, 15 November 2023, 116358
The water extract of Potentilla discolor Bunge (PDW) ameliorates high-sugar diet-induced type II diabetes model in Drosophila melanogaster via JAK/STAT signaling
Ying Li a,1, Junlin Wang a,1, Yidong Xu a, Qinghao Meng a, Mengdi Wu a, Yanfang Su a,*, Yaodong Miao b,**, Yiwen Wang
doi : 10.1016/j.jep.2023.116760
Volume 316, 15 November 2023, 116760
An ethnopharmacological survey of medicinal plants traditionally used by the BaKalanga people of the Tutume subdistrict in Central Botswana to manage HIV/AIDS, HIV-associated conditions, and other health conditions
Khumoekae Richard a,b, Kerstin Andrae-Marobela c,d,**, Ian Tietjen
doi : 10.1016/j.jep.2023.116759
Volume 316, 15 November 2023, 116759
Exploring the effect and mechanism of Haizao Yuhu decoction containing three variants of glycyrrhiza on goiter using an integrated strategy of network pharmacology and RNA sequencing
Muyun Li, Linlin Xiu, Wenyong Liao, Yuna Ren, Min Huo, Haiyan Liu, Shaohong Chen, Na Li, Yuan Gao, Xue Yu, Angran Fan, Gansheng Zhong
doi : 10.1016/j.jep.2023.116750
Volume 316, 15 November 2023, 116750
Reduction of oral pathogens and oxidative damage in the CAL 27Â cell line by Rosmarinus officinalis L. and Taraxacum officinale Web. extracts
Ana Hu?ek Turkovi´c a,*,1, Ksenija Durgo a,1, Florentina ?Cu?ckovi´c a, Ivana Ledenko a, Tena Krizmani´c a, Arijana Martini´c a, Aleksandra Vojvodi´c Cebin a, Dra?zenka Komes a, Mirta Mili´c b
doi : 10.1016/j.jep.2023.116761
Volume 316, 15 November 2023, 116761
Jing-Fang n-butanol extract and its isolated JFNE-C inhibit ferroptosis and inflammation in LPS induced RAW264.7 macrophages via STAT3/p53/SLC7A11 signaling pathway
Xiangyu Li a,b, Hu Qi a,b, Xiongwei Zhang a,b, Huan Liang a,b, Nan Zeng
doi : 10.1016/j.jep.2023.116689
Volume 316, 15 November 2023, 116689
Deciphering the anti-renal fibrosis mechanism of triptolide in diabetic nephropathy by the integrative approach of network pharmacology and experimental verification
Decai Fan a,1, Zi Ying a,1, Ying Yang a, Qi Qian b, Yuanyuan Li b, Panjun Wang b, Xiaofei An b,**, Ming Yan
doi : 10.1016/j.jep.2023.116774
Volume 316, 15 November 2023, 116774
Anti-arrhythmia potential of honey-processed licorice in zebrafish model: Antioxidant, histopathological and tissue distribution
Wenxin Wang a,b, Yinting Yu b, Huixian Chen b, Peijun Sun b, Lujie Lu b, Shuwei Yan a, Xunhong Liu b, Tulin Lu b, Weidong Li b, Jining Liu a,*, Lihong Chen
doi : 10.1016/j.jep.2023.116724
Volume 316, 15 November 2023, 116724
Bufei huoxue capsule alleviates bleomycin-induced pulmonary fibrosis in mice via TGF-β1/Smad2/3 signaling
Yuanyuan Li a,1, Wenguang Qin b,1, Qiuling Liang a,1, Jiamin Zeng a, Qiong Yang c, Yuqin Chen a, Jian Wang a, Wenju Lu
doi : 10.1016/j.jep.2023.116733
Volume 316, 15 November 2023, 116733
Study on the mechanism of Shuganzhi Tablet against nonalcoholic fatty liver disease and lipid regulation effects of its main substances in vitro
Jie Tang a,1, Lixiang Wang a,1, Mengge Shi b, Shuaixia Feng a, Tong Zhang a,**, Han Han
doi : 10.1016/j.jep.2023.116780
Volume 316, 15 November 2023, 116780
Paeonia lactiflora Pall. Polysaccharide alleviates depression in CUMS mice by inhibiting the NLRP3/ASC/Caspase-1 signaling pathway and affecting the composition of their intestinal flora
Zijun Zhou a,1, Yuliang Wang a,1, Shiqing Sun a, Kai Zhang a, Lihong Wang b, Hong Zhao b,**, Yu Zhang
doi : 10.1016/j.jep.2023.116716
Volume 316, 15 November 2023, 116716
Saikosaponin B2 ameliorates depression-induced microglia activation by inhibiting ferroptosis-mediated neuroinflammation and ER stress
Xinmei Wang a,1, Shanshan Li b,c,1, Jiayu Yu a, Wenlin Wang a, Zhuoqi Du a, Shuchun Gao a, Yin Ma a, Ruixin Tang a, Ting Liu a, Shiping Ma a, Qiang Fu a,**, Xueyang Deng
doi : 10.1016/j.jep.2023.116729
Volume 316, 15 November 2023, 116729
Antidiarrheal coumarins from Psydrax schimperianus (A. Rich.) Bridson roots
Getahun Damissie a,b, Ketema Tolossa c, Ariaya Hymete a, Solomon Tadesse
doi : 10.1016/j.jep.2023.116705
Volume 316, 15 November 2023, 116705
Corrigendum to “Integrating network pharmacology and transcriptomic validation to investigate the efficacy and mechanism of Mufangji decoction preventing lung cancer� [J. Ethnopharmacol. 298 (2022) 1–14/115573]
Fan Gao a,1, Yuju Niu a,1, Luyao Sun a, Wenwen Li a, Haojie Xia a, Yaru Zhang a, Shengnan Geng b, Zhenzhen Guo a, Haihong Lin a,*, Gangjun Du
doi : 10.1016/j.jep.2023.116668
Volume 316, 15 November 2023, 116668
Corrigendum to “Shaoyao decoction restores the mucus layer in mice with DSS-induced colitis by regulating Notch signaling pathway� [J. Ethnopharmacol. 308 (2023) 116258]
Yu-Xi Fang a,b,1, You-Qian Liu a,1, Yi-Min Hu b, Yuan-Yuan Yang b, Dong-Jian Zhang c, Cui-Hua Jiang c, Jian-Hua Wang b,**, Jian Zhang
doi : 10.1016/j.jep.2023.116726
Volume 316, 15 November 2023, 116726
