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Effect of arctigenin on neurological diseases: A review
Mopu Li a, Haibin Jiang a, Yanan Wang a, Zidi Xu a, Hang Xu b, Yuetong Chen b, Jianghu Zhu c,d,e,f,**, Zhenlang Lin c,d,e,f,***, Min Zhang
doi : 10.1016/j.jep.2023.116642
Volume 315, 28 October 2023, 116642
Artemisia anomala S. Moore: A review of botany, traditional uses, phytochemistry, pharmacology and quality control
Junyu Liu a,1, Peiyu Xiong a,1, Lehong Huang b, Wei Zhang a, Li Song a, Hengchang Hu a, Bo Jia a,*, Xinglong Liu
doi : 10.1016/j.jep.2023.116663
Volume 315, 28 October 2023, 116663
Potential application of Atractylodes macrocephala Koidz. as a natural drug for bone mass regulation: A review
Yikang Yu a,1, Danqing Fu b,1, Hengpu Zhou a, Jie Su a,*, Suhong Chen c,***, Guiyuan Lv
doi : 10.1016/j.jep.2023.116718
Volume 315, 28 October 2023, 116718
Integrating metabonomics and metagenomics sequencing to study the anti-liver fibrosis effects of palmatine in Corydalis saxicola Bunting
Jinghua Qin a,1, Zhuo Luo a,1, Qianyi Wang a,1, Chaoling Tang a,b, Mingwei Meng a, Zheng Huang a, Bingjian Guo a, Ying He c, Linlin Feng a, Yunyuan Nong a, Lijun Deng a, Dan Zhu a, Hongwei Guo a,**, Yonghong Liang a,***, Zhiheng Su
doi : 10.1016/j.jep.2023.116666
Volume 315, 28 October 2023, 116666
Paeoniae Radix Rubra extract attenuates cerebral ischemia injury by inhibiting ferroptosis and activating autophagy through the PI3K/Akt signalling pathway
Fengyan Zhao a,b,c, Caiwang Peng a,b,c, Hengli Li a,b,c, Haodong Chen a,b, Yantao Yang a,b, Qidi Ai a,b, Naihong Chen a,b,d,**, Fang Liu
doi : 10.1016/j.jep.2023.116567
Volume 315, 28 October 2023, 116567
A novel perspective on the preventive treatment of hydrazine compound-induced liver injury: Isoniazid liver injury as an example
Xinyu Li a,b,1, Chengxian Li b,d,1, Chenyi Li c,e,1, Chengzhao Wu a,b, Yuxuan Bai c, Xu Zhao b, Zhaofang Bai b, Xigang Zhang c,*, Xiaohe Xiao a,b,**, Ming Niu
doi : 10.1016/j.jep.2023.116616
Volume 315, 28 October 2023, 116616
QiShenYiQi pill inhibits atherosclerosis by promoting reverse cholesterol transport PPARγ-LXRα/β-ABCA1 pathway
Jing Xie a, Li Peng b,*, Taotao wang a, Chengyong Yang a, Nanting Chen a, Xue Feng a, Tingchun Wu b, Tao Xu b, Yunzhi Chen
doi : 10.1016/j.jep.2023.116684
Volume 315, 28 October 2023, 116684
Topical application of aerial portion of Acalypha indica Linn ameliorates psoriasis in rodents: Evidences from in vivo and in silico studies
Anurag Agrawal a,b,c, Giriraj T. Kulkarni d,*, Lakshmayya
doi : 10.1016/j.jep.2023.116685
Volume 315, 28 October 2023, 116685
Diversified cassane family diterpenoids from the leaves of Caesalpinia minax exerting anti-neuroinflammatory activity through suppressing MAPK and NF-κB pathways in BV-2 microglia
Wang Lu a,1, Jin-Ting Chen a,1, Ye-Fan Shi a, Meng-Song Chen a, Pan-Pan Wang a, Xiu-Juan Zhang a, Chao-Jiang Xiao b, Ding Li a, Chen-Yu Cao a,**, Chun-Huan Li a,*, Jin-Ming Gao
doi : 10.1016/j.jep.2023.116653
Volume 315, 28 October 2023, 116653
Effects of Rheum rhaponticum and Rheum rhabarbarum extracts on haemostatic activity of blood plasma components and endothelial cells in vitro
Oleksandra Liudvytska a,*, Micha? B. Ponczek a, Justyna Krzy?zanowska-Kowalczyk c, Mariusz Kowalczyk c, Aneta Balcerczyk b, Joanna Kolodziejczyk-Czepas
doi : 10.1016/j.jep.2023.116562
Volume 315, 28 October 2023, 116562
Jiedu-Quyu-Ziyin Fang (JQZF) inhibits the proliferation and activation of B cells in MRL/lpr mice via modulating the AKT/mTOR/c-Myc signaling pathway
YiNi Gao a,1, JiaWang Zhou a,1, Yao Huang b,1, MeiJiao Wang a, Yi Zhang a, FengQi Zhang a, Yan Gao a, YiYang Zhang a, HaiChang Li a, Jing Sun c,**, ZhiJun Xie
doi : 10.1016/j.jep.2023.116625
Volume 315, 28 October 2023, 116625
Integration of non-targeted metabolomics with network pharmacology deciphers the anxiolytic mechanisms of Platycladi Semen extracts in CUMS mice
Jiaqi Xie , Yihong Li , Yulu Liang , Hongqian Kui , Can Wang **, Jianmei Huang
doi : 10.1016/j.jep.2023.116571
Volume 315, 28 October 2023, 116571
Medicinal and edible plant Allium macrostemon Bunge for the treatment of testosterone-induced androgenetic alopecia in mice
Ruiyang Gao 1, Zhilun Yu 1, Cheng Lv, Xiaolong Geng, Yijing Ren, Junyu Ren, Hao Wang, Fangbin Ai, Beibei Zhang, Bei Yue *, Zhengtao Wang **, Wei Dou
doi : 10.1016/j.jep.2023.116657
Volume 315, 28 October 2023, 116657
Methanolic extract of O.umbellata L. exhibits anti-osteoporotic effect via promoting osteoblast proliferation in MG-63Â cells and inhibiting osteoclastogenesis in RANKL-stimulated RAW 264.7Â cells
Sivasakthi Paramasivam a, Senthamil Selvan Perumal
doi : 10.1016/j.jep.2023.116641
Volume 315, 28 October 2023, 116641
Analysis of target organs of Houttuynia cordata: A study on the anti-inflammatory effect of upper respiratory system
Tin-Yun Ho a,b, Hsin-Yi Lo a, Guan-Ling Lu c, Pei-Yung Liao a,d, Chien-Yun Hsiang
doi : 10.1016/j.jep.2023.116687
Volume 315, 28 October 2023, 116687
Study on the difference and correlation between the contents and toxicity of aristolochic acid analogues in Aristolochia plants
Jingzhuo Tian 1, Chenyue Liu 1, Lianmei Wang , Zhong Xian , Yong Zhao , Shasha Qin , Yan Yi , Chunying Li , Jiayin Han , Chen Pan , Yushi Zhang , Suyan Liu , Jing Meng , Xuan Tang , Fang Wang , Meiting Liu , Aihua Liang
doi : 10.1016/j.jep.2023.116568
Volume 315, 28 October 2023, 116568
Therapeutic effect of the total saponin from Panax Japonicus on experimental autoimmune encephalomyelitis by attenuating inflammation and regulating gut microbiota in mice
Jing Wang 1, Liying He 1, Siyuan Wang, Hui Zhao, Jie Chen, Yixin Dong , Subinuer Yasen, Lei Wang , Haiyan Zou
doi : 10.1016/j.jep.2023.116681
Volume 315, 28 October 2023, 116681
Evaluation of 43 species of Congolese medicinal plants used traditionally for the treatment of schistosomiasis leading to the isolation of an anti-schistosomal phaeophytin from Pseudolachnostylis maprouneifolia Pax.
Kalunga Muya a, Mbuyi Kalonji a, Numbi wa Ilunga a, Mwamba Maseho c, Mbayo Kitambala b, Mutombo Kalonda b, Kalonji Ndoumba a, Kahumba Byanga a, Colin W. Wright d,*, C´ecile H¨aberli e,f, Jennifer Keiser e,f, Lumbu Simbi
doi : 10.1016/j.jep.2023.116688
Volume 315, 28 October 2023, 116688
The mechanism of action of safflower total flavonoids in the treatment of endometritis caused by incomplete abortion based on network pharmacology and 16S rDNA sequencing
Yan Chen a,b,c, Qiwen Xiang c, Fu Peng a,d, Song Gao c, Lei Yu a,b, Yunli Tang a,b, Zhou Yang c, Wei Pu c, Xiaofang Xie a,b,**, Cheng Peng
doi : 10.1016/j.jep.2023.116639
Volume 315, 28 October 2023, 116639
Efficacy of mecasin for treatment of amyotrophic lateral sclerosis: A phase IIa multicenter randomized double-blinded placebo-controlled trial
Sungha Kim a,1, Muhack Yang b,1, Boncho Ku a, Eunhye Cha b, Wookcheol Seo b, Ilhong Son c, Hyungwon Kang d, Dongwoung Kim a, Bongkeun Song e, Chang-Sop Yang a, Sungchul Kim
doi : 10.1016/j.jep.2023.116670
Volume 315, 28 October 2023, 116670
Chemical composition and cardiotropic activity of Ziziphora clinopodioides subsp. bungeana (Juz.) Rech.f.
A.O. Whaley b, D.Y. Ivkin a,1, K.A. Zhaparkulova e, I.N. Olusheva b, E.B. Serebryakov d, S.N. Smirnov d, E.D. Semivelichenko a, A. Yu. Grishina a, A.A. Karpov a, E.I. Eletckaya a, K.K. Kozhanova e, L.N. Ibragimova e, K.T. Tastambek f,g, A.M. Seitaliyeva h, I.I. Terninko c, Z.B. Sakipova e, A.N. Shikov b, M.N. Povydysh b,*, A.K. Whaley
doi : 10.1016/j.jep.2023.116660
Volume 315, 28 October 2023, 116660
Zhuidu Formula suppresses the migratory and invasive properties of triple-negative breast cancer cells via dual signaling pathways of RhoA/ROCK and CDC42/MRCK
Qinhang Wu , Xuelin Ma , Zhuolin Jin , Ruijun Ni , Yang Pan **, Guangming Yang
doi : 10.1016/j.jep.2023.116644
Volume 315, 28 October 2023, 116644
Polyphenolic compounds of Phyllanthus amarus Schum & Thonn. (1827) and diabetes-related activity of an aqueous extract as affected by in vitro gastrointestinal digestion
elissa Matou a,b, Patrick Merciris a,c,1, Mayra Luz Sanchez-Villavicencio d, Ga¨etan Herbette e, Remi Neviere b, Pierre Haddad d, Th´er`ese Marianne-Pepin a,c, Sylvie Bercion
doi : 10.1016/j.jep.2023.116619
Volume 315, 28 October 2023, 116619
1-Tetracosanol isolated from the leaves of Eupatorium glandulosum, accelerates wound healing by expressing inflammatory cytokines and matrix metalloproteinase
Ramalingam Shalini a, Moola Joghee Nanjan Chandrasekar *,b, Moola Joghee Nanjan c, SubbaRao V. Madhunapantula d, Medha Karnik d, Jubi Selvaraj a, Gonna Nandhi Krishnan Ganesh
doi : 10.1016/j.jep.2023.116654
Volume 315, 28 October 2023, 116654
To study the protective effect of Huangqi Baihe Granules on Radiation brain injury based on network pharmacology and experiment
Xiuzhu Liu a,1, Jiawei Li a,1, Yanru Wang a,1, Bingbing Wu b, Siyu Wang a, Qingyang Guo a, Yongqi Liu
doi : 10.1016/j.jep.2023.116610
Volume 315, 28 October 2023, 116610
Pharmacokinetic and metabolite profile of orally administered anemoside B4 in rats with an improved exposure in formulations of rectal suppository
Yaqing Ye a,b,c,1, Mingzhen Xue b,d,1, Xiaoting Tian b, Hongwei Gao e, Pei Hu b, Linwei Wang b,f, Jing Leng a,c,*, Yaru Xue b,**, Chenggang Huang
doi : 10.1016/j.jep.2023.116694
Volume 315, 28 October 2023, 116694
FTZ promotes islet β-cell regeneration in T1DM mice via the regulation of nuclear proliferation factors
Qin Zhong a,b,1, Jianying Yin a,b,1, Ke Wang a,b,1, Xu Chen a,b,1, Hong Wang a,b, Xuguang Hu a,b, Weixuan Wang a,b, Lexun Wang a,b, Weijian Bei a,b,c,d,*, Jiao Guo
doi : 10.1016/j.jep.2023.116564
Volume 315, 28 October 2023, 116564
Network pharmacology and experiments in vivo and in vitro reveal that the Jia-Wei-Bu-Shen-Yi-Qi formula (JWBSYQF) and its active ingredient baicalein ameliorate BLM-induced lung fibrosis in mice via PI3K/Akt signaling pathway
Hanlin Shi a,b,1, Lingling Deng a,b, Yaolong Zhou a,b, Hang Yu a,b, Xi Huang a,b, Mengmeng Chen a,b, Yang Lei a,b,**, Jingcheng Dong
doi : 10.1016/j.jep.2023.116691
Volume 315, 28 October 2023, 116691
System pharmacology analysis to decipher the effect and mechanism of active ingredients combination from Duhuo Jisheng decoction on osteoarthritis in rats
Senwang Zheng a,1, Bo Zhou c,1, Lin Yang a,b, Ajiao Hou a, Jiaxu Zhang a, Huan Yu a, Haixue Kuang a, Hai Jiang a,**, Liu Yang
doi : 10.1016/j.jep.2023.116679
Volume 315, 28 October 2023, 116679
Dingkun Pill modulate ovarian function in chemotherapy-induced premature ovarian insufficiency mice by regulating PTEN/PI3K/AKT/FOXO3a signaling pathway
Chan Su a, Ruihong Zhang c, Xiujuan Zhang a, Mengxiao Lv a, Xiang Liu b, Kai Ao b, Jing Hao c,**, Yu-lan Mu
doi : 10.1016/j.jep.2023.116703
Volume 315, 28 October 2023, 116703
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways
Ying Gao a,1, Li-Juan Lu b,1, Zhao-Zheng Zhang a, Xiao Yang a, Jun Du a, Ke Wen a, Hua Huang c, Xiao-Peng Wang a,**, Xue-Liang Sun
doi : 10.1016/j.jep.2023.116678
Volume 315, 28 October 2023, 116678
Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice
Pan Su a, Mengdi Wu a, Xiaoting Yin a,b, Mengyuan Li a,b, Yucheng Li a, Ming Bai a,**, Baoying Wang a,***, Erping Xu
doi : 10.1016/j.jep.2023.116659
Volume 315, 28 October 2023, 116659
Huang-Lian-Jie-Du decoction alleviates depressive-like behaviors in dextran sulfate sodium-induced colitis mice via Trem2/Dap12 pathway
Jia-Yi Zheng a,b,c,d,1, Xiao-Xiao Li d,e,1, Wei-Yao Lin f, Shan Su g, Hai-Cui Wu h, Rui-Dan Hu f, Hua-Feng Pan a,b,i, Jiang-Hong Ye j,**, Ye-Feng Cai a,b,c,***, Shi-Jie Zhang
doi : 10.1016/j.jep.2023.116658
Volume 315, 28 October 2023, 116658
Antibiofilm potential of Annona muricata L. ethanolic extract against multi-drug resistant Candida albicans
Lara Melo Campos a, Thiago P. Silva b, Ari S´ergio de Oliveira Lemos a, Irley Ol?via Mendonça Diniz a, Cinthia Palazzi b, Vin?cius Novaes da Rocha c, Marcelo Gonzaga de Freitas Ara?jo d, Rossana C.N. Melo b, Rodrigo Luiz Fabri
doi : 10.1016/j.jep.2023.116682
Volume 315, 28 October 2023, 116682
SMRGAT: A traditional Chinese herb recommendation model based on a multi-graph residual attention network and semantic knowledge fusion
Xiaoyan Yang a, Changsong Ding
doi : 10.1016/j.jep.2023.116693
Volume 315, 28 October 2023, 116693
Multi-omics approach for identification of molecular alterations of QiShenYiQi dripping pills in heart failure with preserved ejection fraction
Yuting Huang a,b,1, Kai Zhang a,d,e,1, Xiao Wang a,d, Kaimin Guo c, Xiaoqiang Li c, Feng Chen a,d, Ruijiao Du d, Sheng Li a,d, Lan Li d, Zhihui Yang a,d, Danping Zhuo a,d, Bingkai Wang a,d, Wenjia Wang c, Yunhui Hu c,**, Miaomiao Jiang d,***, Guanwei Fan
doi : 10.1016/j.jep.2023.116673
Volume 315, 28 October 2023, 116673
Unveiling hepatotoxicity distinction of coumarin-related compounds from glycosides to aglycones in Fructus Psoraleae by integrating UPLC-Q-TOF-MS and high content analysis
Benyu Liu a,1, Shiming Fang a,1, Kun Zhou a,b,c, Lulu Ma a, Yaling Shi a, Yuefei Wang a,c,*, Xiumei Gao
doi : 10.1016/j.jep.2023.116664
Volume 315, 28 October 2023, 116664
Tanshinone IIA inhibited intermittent hypoxia induced neuronal injury through promoting autophagy via AMPK-mTOR signaling pathway
Jianchao Si a,1, Bingbing Liu a,1, Kerong Qi a, Xue Chen a, Dongli Li a, Shengchang Yang a,b,**, Ensheng Ji
doi : 10.1016/j.jep.2023.116677
Volume 315, 28 October 2023, 116677
Pinellia ternata (Thunb.) Breit. attenuates the allergic airway inflammation of cold asthma via inhibiting the activation of TLR4-medicated NF-kB and NLRP3 signaling pathway
Xingbao Tao a,b, Juan Li c, Jun He d, Yunbin Jiang e, Chunshan Liu c, Weiguo Cao a,*, Hao Wu
doi : 10.1016/j.jep.2023.116720
Volume 315, 28 October 2023, 116720
Elucidating the pharmacological effects of Compound Kushen injection on MYC-P15-CCND1 signaling pathway in nasopharyngeal carcinoma - An in vitro study
Zhishan Wu a, Chao Wu a, Jian Shi b, Zhihong Huang a, Shan Lu a, Yingying Tan a, Rongli You c, Lina Hai c, Jiaqi Huang a, Siyu Guo a, Yifei Gao a, Zhengsen Jin a, Xiaoyu Tao a, Leiming You d,**, Jiarui Wu
doi : 10.1016/j.jep.2023.116702
Volume 315, 28 October 2023, 116702
