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Advances in autophagy modulation of natural products in cervical cancer
Tao Tao a, Ping Zhang b, Zhi Zeng a, Min Wang
doi : 10.1016/j.jep.2023.116575
Volume 314, 5 October 2023, 116575
Pharbitidis Semen: A review of botany, traditional uses, phytochemistry, pharmacology, and toxicology
Peiyun Gao a,b, Lixia Wang a, Yingying Chen a, Xiaoyun Yang a, Xiaoxu Chen a, Chunyu Yue a,b, Tong Wu a, Tong Jiang a, Hongwei Wu a, Liying Tang a,*, Zhuju Wang
doi : 10.1016/j.jep.2023.116634
Volume 314, 5 October 2023, 116634
The processing methods, phytochemistry and pharmacology of Gastrodia elata Bl.: A comprehensive review
Zenghu Su a,1, Yuangui Yang a,*,1, Shizhong Chen a,b, Zhishu Tang a,c, Hongbo Xu
doi : 10.1016/j.jep.2023.116467
Volume 314, 5 October 2023, 116467
The effectiveness of blood-activating and stasis-transforming traditional Chinese medicines (BAST) in lung cancer progression-a comprehensive review
Siqi Wu a, Zhe Sun a, Zehuai Guo a, Peiqin Li a, Qianqian Mao a, Yang Tang a, Hongyu Chen a, Huiting Peng a, Sisi Wang b, Yang Cao
doi : 10.1016/j.jep.2023.116565
Volume 314, 5 October 2023, 116565
Genus Equisetum L: Taxonomy, toxicology, phytochemistry and pharmacology
J. Sureshkumar a,*, C. Jenipher b, V. Sriramavaratharajan c, S.S. Gurav d, G. Rajiv Gandhi e, K. Ravichandran f, M. Ayyanar
doi : 10.1016/j.jep.2023.116630
Volume 314, 5 October 2023, 116630
Geniposide ameliorates atherosclerosis by regulating macrophage polarization via perivascular adipocyte-derived CXCL14
Peikun He a,1, Hao Wang a,1, Saibo Cheng a, Fang Hu a, Lifang Zhang a, Weicong Chen a, Yuling Xu b, Yaxin Zhang a, Yuyan Gu a, Zhaoyong Li a, Yao jin a, Xiaoyu Liu c,**, Yuhua Jia
doi : 10.1016/j.jep.2023.116532
Volume 314, 5 October 2023, 116532
Network pharmacology integrated with experimental validation revealed potential molecular mechanisms of Camellia nitidissima C. W. Chi in the treatment of lung cancer
Ailing Zhou a, Chong Zhou b,*, Duanheng Wang a, Mingming Qian b, Li Huang
doi : 10.1016/j.jep.2023.116576
Volume 314, 5 October 2023, 116576
Transcriptomic analysis reveals that the anti-PCOS effects of Zishen Qingre Lishi Huayu recipe may involve pathways and genes related to autophagy, steroidogenesis, oxidative stress, and inflammation in granulosa cells
Ruining Liang a,b,c, Mengzhen Sheng a, Xin Li a, Jing Jin a, Yao Yi
doi : 10.1016/j.jep.2023.116551
Volume 314, 5 October 2023, 116551
Taohong siwu decoction ameliorates cognitive dysfunction through SIRT6/ER stress pathway in Alzheimer's disease
Hong-Yu Tan a,b,c,1, Can Wan a,b,1, Guang-Liang Wu a,b,1, Li-Jun Qiao a,b, Ye-Feng Cai a,b,d,**, Qi Wang c,***, Shi-Jie Zhang
doi : 10.1016/j.jep.2023.116580
Volume 314, 5 October 2023, 116580
Toxicological potential of Aloysia gratissima: Insights from chemical analysis and in vitro studies
Francisco Laerte Lopes da Silva a,1, Amanda Souza Scotti a,1, Ana Let?cia Hil´ario Garcia a,b, Maria Luiza Brodt Lemes a, Ivana Grivicich a, Gabriela Mendonça dos Reis a, Johnny Ferraz Dias c, Fernanda Bri?ao Menezes Boaretto a, Jaqueline Nascimento Picada a, Juliana da Silva a,b,**, Alexandre de Barros Falc?ao Ferraz
doi : 10.1016/j.jep.2023.116614
Volume 314, 5 October 2023, 116614
Impact of Eucalyptus maculata Hook resin exudate constituents on reducing COX-2 gene expression: In-vivo anti-inflammatory, molecular docking and dynamics studies
Manal M. Sabry a,*, Rehab F. Abdel-Rahman b, Hany M. Fayed b, Azza T. Taher c,d, Hanan A. Ogaly e, Amgad Albohy f,g, Sabah H. El-Gayed a,h, Rana M. Ibrahim
doi : 10.1016/j.jep.2023.116631
Volume 314, 5 October 2023, 116631
Effect of Jiawei Tongqiao Huoxue decoction in basilar artery dolichoectasia mice through yes-associated protein/transcriptional co-activator with PDZ-binding motif pathway
Fei Xiang Liu a,b,c, Dao Pei Zhang a,b,c,*, Yan Min Ma d, Huai Liang Zhang a,b,c, Xiang Zhe Liu a, Zhen Qiang Zhang e, Rui Qin Sun f, Yun Ke Zhang a,g,**, Jin Xin Miao f, Zhao Xin Wu d, Ya Li Liu d, Yan Chen Feng
doi : 10.1016/j.jep.2023.116599
Volume 314, 5 October 2023, 116599
A screening strategy for bioactive components of Bu-Zhong-Yi-Qi-Tang regulating spleen-qi deficiency based on “endobiotics-targets-xenobiotics� association network
Liufang Hu a,b,1, Jiali Chen a,1, Huifang Duan a, Zhenyu Zou a, Yuan Qiu a, Jing Du c,**, Jiaxu Chen b, Xinsheng Yao a, Hiroaki Kiyohara d, Takayuki Nagai d,***, Zhihong Yao
doi : 10.1016/j.jep.2023.116605
Volume 314, 5 October 2023, 116605
“Cerastes snake venom as a promising approach in the management of complete Freund's adjuvant-induced rheumatoid arthritis in rats: Involvement of RANKL and JAK/STAT pathway�
Nourhan S. Soliman a,*, Mohamed A. Kandeil b, Marwa M. Khalaf
doi : 10.1016/j.jep.2023.116577
Volume 314, 5 October 2023, 116577
Diospyros malabarica fruit preparation mediates immunotherapeutic modulation and epigenetic regulation to evoke protection against non–small cell lung cancer (NSCLC)
Sannidhi Bhootra a, Nandana Jill a, Rohit Rajak a, Geetha Shanmugam a, Sudeshna Rakshit a, Samiyah Kannanthodi a, Vidhi Thakkar a, Melvin George b, Koustav Sarkar
doi : 10.1016/j.jep.2023.116525
Volume 314, 5 October 2023, 116525
ZeXieYin Formula alleviates TMAO-induced cognitive impairment by restoring synaptic plasticity damage
Jing Liu a,b,1, Shihan Zhou a,b,1, Yanqing Wang a,b, Jinling Liu a,b, SuPing Sun a,b, Yan Sun a,b, Ping Xu a,b, Xu Xu c, Boran Zhu a,b,*, Haoxin Wu
doi : 10.1016/j.jep.2023.116604
Volume 314, 5 October 2023, 116604
An integrated network pharmacology approach reveals that Darutigenol reduces inflammation and cartilage degradation in a mouse collagen-induced arthritis model by inhibiting the JAK-STAT3 pathway
Yong Wang a, Hui Yan a, Long Zhao a, Xue-Lai He b,c, Te-Ri-Gen Bao a, Xian-Duo Sun a, Yong-Cheng Yang a, Shu-Yi Zhu a, Xiao-Xu Gao a, An-Hua Wang a,*, Jing-Ming Jia
doi : 10.1016/j.jep.2023.116574
Volume 314, 5 October 2023, 116574
In vitro and in vivo anti-inflammatory activity of Cupressus torulosa D.DON needles extract and its chemical characterization
Radhika Khanna a, H.R. chitme b, Khushaboo Bhadoriya a, Y.C. Tripathi a, V.K. Varshney
doi : 10.1016/j.jep.2023.116578
Volume 314, 5 October 2023, 116578
Combined Epimedii Folium and Ligustri Lucidi Fructus with dexamethasone alleviate the proliferation of airway smooth muscle cells by regulating apoptosis/autophagy
Yuting Long a,1, Han Wang a,1, Zitong Ma a, Yuman Li a, Zaina Ma a, Ping Yu a, Xiufeng Tang b, Renhui Liu
doi : 10.1016/j.jep.2023.116547
Volume 314, 5 October 2023, 116547
Geniposide ameliorates dextran sulfate sodium-induced ulcerative colitis via KEAP1-Nrf2 signaling pathway
Xiaoju Zhuge a, Xiaosheng Jin a, Tingting Ji a, Rongzhou Li a, Liwei Xue a, Weilai Yu a, Zijiao Quan b, Haibin Tong b,*, Fang Xu
doi : 10.1016/j.jep.2023.116626
Volume 314, 5 October 2023, 116626
Paris polyphylla extract attenuates colitis in mice by regulating PPAR-γ mediated Treg/Th17 balance
Long He a,f, Xingrui Yan b, Shuting Wen c, Zhuotai Zhong d, Zhengkun Hou a, Fengbin Liu a,e,f, Hong Mi
doi : 10.1016/j.jep.2023.116621
Volume 314, 5 October 2023, 116621
Effects of Banxia Xiexin Decoction on apoptosis of interstitial cells of Cajal via regulation of MiR-451-5p: An in vivo and in vitro study
Di Zhang a,1, Ruimin Lu a,1, Mengwei Wang a,1, Jing Ji a, Shujing Zhang a, Shuyan Wang a,***, Dongmei Zhang b,**, Meng Chen
doi : 10.1016/j.jep.2023.116606
Volume 314, 5 October 2023, 116606
Rhynchophylline inhibits methamphetamine dependence via modulating the miR-181a-5p/GABRA1 axis
Ming-Jin Jiang a,b, Jing Li b, Chao-Hua Luo b, Chen Zhu b, Zhi-Jie Chen b, Wei Bai a, Tian-Yu Hu a, Chuan-Hua Feng a, Chan Li c,**, Zhi-Xian Mo
doi : 10.1016/j.jep.2023.116635
Volume 314, 5 October 2023, 116635
Platycodin D inhibits HFD/STZ-induced diabetic nephropathy via inflammatory and apoptotic signaling pathways in C57BL/6 mice
Qiong Shen a,b,1, Si-min Qi a,1, Jing-tian Zhang a, Ming-han Li a, Ying-ping Wang a,b, Zi Wang a, Wei Li
doi : 10.1016/j.jep.2023.116596
Volume 314, 5 October 2023, 116596
Xinkeshu tablets promote angiogenesis in zebrafish embryos and human umbilical vein endothelial cells through multiple signaling pathways
Qing Liu a,b,1, Huazheng Zhang c,1, Ying An a,b,1, Yun Zhang a, Qiuxia He a, Kechun Liu a, Qing Xia a,*, Honglei Zhou
doi : 10.1016/j.jep.2023.116636
Volume 314, 5 October 2023, 116636
Mongolian medicine formulae Ruda-6 alleviates indomethacin-induced gastric ulcer by regulating gut microbiome and serum metabolomics in rats
Lan Feng a,b,1, Terigele Bao a,1, Laxinamujila Bai a, Xiyele Mu a, Na Ta a, Minglan Bao a, Yonghui Li b, Junqing Zhang b, Minghai Fu a,b,*, Yongsheng Chen
doi : 10.1016/j.jep.2023.116545
Volume 314, 5 October 2023, 116545
Combination treatment of Danggui Buxue Decoction and endothelial progenitor cells can enhance angiogenesis in rats with focal cerebral ischemia and hyperlipidemia
Yonghui Dou a, Yue Shu a, Yaoyu Wang a, Dan Jia b, Zhengyun Han a, Beiyin Shi a, Jieying Chen a, Jie Yang a, Zhen Qin c,**, Shuiqing Huang
doi : 10.1016/j.jep.2023.116563
Volume 314, 5 October 2023, 116563
Evaluation potential effects of Picroside II on cytochrome P450 enzymes in vitro and in vivo
Nan Zhou a,c, Yujie Zhu b, Miaorong Hu b, Rongyao Zheng b, Mengqi Sun c, Yueying Bian c, Xijing Chen c,**, Tingting Li
doi : 10.1016/j.jep.2023.116582
Volume 314, 5 October 2023, 116582
Bioactive compounds and mechanism of Xianglian pill in the treatment of gastric cancer: Network pharmacology analysis and experimental validation
Lei Yu a, Luyao Sun a, Qian Yu a, Fang Xiong a, Daibo Wang a, Lin Pu a, Fu Peng b,*, Xiaofang Xie a,**, Cheng Peng
doi : 10.1016/j.jep.2023.116573
Volume 314, 5 October 2023, 116573
Reduction in gefitinib resistance mediated by Yi-Fei San-Jie pill in non-small cell lung cancer through regulation of tyrosine metabolism, cell cycle, and the MET/EGFR signaling pathway
Cai-Zhi Yang a,1, Wei Guo b,1, Yi-Fan Wang a,1, Lei-Hao Hu a, Jing Wang c, Jia-Min Luo a, Xiao-Hui Yao d, Shan Liu a, Lan-Ting Tao e, Ling-Ling Sun b,**, Li-Zhu Lin
doi : 10.1016/j.jep.2023.116566
Volume 314, 5 October 2023, 116566
Seabuckthorn Wuwei Pulvis attenuates chronic obstructive pulmonary disease in rat through gut microbiota-short chain fatty acids axis
JunMei Wang a, Chunxiu Ren b, Lingling Jin a, Wuliji Batu
doi : 10.1016/j.jep.2023.116591
Volume 314, 5 October 2023, 116591
Isolation and characterization of natural inhibitors of post-proline specific peptidases from the leaves of Cotinus coggygria Scop
Ivaylo Ivanov a,*, Anelia Vasileva a, Donka Tasheva b, Mashenka Dimitrova
doi : 10.1016/j.jep.2023.116508
Volume 314, 5 October 2023, 116508
A modified Fangji Huangqi decoction ameliorates pulmonary artery hypertension via phosphatidylinositide 3-kinases/protein kinase B-mediated regulation of proliferation and apoptosis of smooth muscle cells in vitro and in vivo
Zhifeng Xue a,b,c, Mengen Zhou a,b, Yiman Liu a,b, Honglin Qin a,b, Yixuan Li a,b, Yan Zhu a,b,**, Jian Yang
doi : 10.1016/j.jep.2023.116544
Volume 314, 5 October 2023, 116544
Spectrum-effect relationship study to reveal the pharmacodynamic substances in Flos Puerariae-Semen Hoveniae medicine pair for the treatment of alcohol-induced liver damage
Haotian Zhang a,1, Ziyun Wei a,1, Yichen Tong a, Xiuping Song a, Siyue Li a, Yuanfang Sun a, Chun Liu b, Fei Han a,**, Jia Yu
doi : 10.1016/j.jep.2023.116628
Volume 314, 5 October 2023, 116628
Network pharmacology and molecular docking prediction, combined with experimental validation to explore the potential mechanism of Qishen Yiqi pills against HF-related cognitive dysfunction
Song-Jie Han , Qian-Qian Xu 1, Hai’e Pan, Wen-Jing Liu, Qian-Qian Dai, Hong-Yuan Lin, He-Rong Cui, Liang-Zhen You, Yu-Zhuo Wu, Xiao-Hong Wei **, Hong-Cai Shang
doi : 10.1016/j.jep.2023.116570
Volume 314, 5 October 2023, 116570
Protective effect of oleo-gum resin of Commiphora wightii against elastase-induced chronic obstructive pulmonary disease-linked lung inflammation and emphysema: Isolation and identification of key bioactive phytoconstituent
Manpreet Kaur a, Jai Malik b, Amarjit S. Naura
doi : 10.1016/j.jep.2023.116623
Volume 314, 5 October 2023, 116623
Heukharang lettuce (Lactuca sativa L.) leaf extract displays sleep-promoting effects through GABAA receptor
Yejin Ahn a, Hee Hwan Lee b, Byung-Hak Kim b, Sang Jae Park b, Young Suk Kim c, Hyung Joo Suh a,d, Kyungae Jo
doi : 10.1016/j.jep.2023.116602
Volume 314, 5 October 2023, 116602
Qilong capsule alleviates ponatinib-induced ischemic stroke in a zebrafish model by regulating coagulation, inflammation and apoptosis
Shenghua Lin a,1, Xin Liu a,1, Aonan Sun d, Huiliang Liang c, Zhen Li c, Suyan Ye c, Honglin Ma a, Wei Fan a, Chuanlin Shen a, Meng Jin a, Qiuxia He
doi : 10.1016/j.jep.2023.116397
Volume 314, 5 October 2023, 116397
Total tanshinones protect against acute lung injury through the PLCγ2/NLRP3 inflammasome signaling pathway
Xinxing Li a,b,1, Haixin Qiu a,1, Jinyue Gan a, Zhenjie Liu a, Shilin Yang a, Renyikun Yuan a,**, Hongwei Gao
doi : 10.1016/j.jep.2023.116478
Volume 314, 5 October 2023, 116478
Tomentosin suppressed M1 polarization via increasing MERTK activation mediated by regulation of GAS6
Yu-xi Di a, Yu-jie Bao a, Zhi-qi Zhu a, Shan-liang Sun a, Feng-xiang Tian a, Fu-rong Wang a, Ge Yu a, Ming-fei Zhang b, Jing Han a,**, Ling-ling Zhou
doi : 10.1016/j.jep.2023.116429
Volume 314, 5 October 2023, 116429
Tetrastigma polysaccharide reprogramming of tumor-associated macrophages via PPARγ signaling pathway to play antitumor activity in breast cancer
Xia Liu a,1, Xianli Liu b,1, Weiye Mao c, Yingxue Guo c, Ningning Bai c, Lu Jin a, Qiyang Shou a,d,*, Huiying Fu
doi : 10.1016/j.jep.2023.116645
Volume 314, 5 October 2023, 116645
Paeonol, the active component of Cynanchum paniculatum, ameliorated schizophrenia-like behaviors by regulating the PI3K-Akt-GSK3β-NF-κB signalling pathway in MK-801-treated mice
Ho Jung Bae a, Jae Youn Kim b, Seung-Hyuk Choi c, So-Yeon Kim c, Hyun-Jeong Kim c, Ye Eun Cho c, Yu-Yeong Choi c, Ju-Yeon An c, So-Young Cho c, Jong Hoon Ryu b,*, Se Jin Park
doi : 10.1016/j.jep.2023.116627
Volume 314, 5 October 2023, 116627
Protective effects and mechanisms of Yi Qi Huo Xue Fang in cerebral ischemic stroke based on network pharmacology and experimental verification
Jiamin Li a,b, Tiantian Zhang a,b, Kan Liu a, Guoheng Hu
doi : 10.1016/j.jep.2023.116611
Volume 314, 5 October 2023, 116611
Intestines-erythrocytes-mediated bio-disposition deciphers the hypolipidemic effect of berberine from Rhizoma Coptidis: A neglected insight
Ziwei Huang a,1, Minhua Li a,1, Zehui Qin a, Xingdong Ma a, Ronglei Huang a, Yuhong Liu a, Jianhui Xie c,d,e, Huifang Zeng b,**, Ruoting Zhan a,***, Ziren Su
doi : 10.1016/j.jep.2023.116600
Volume 314, 5 October 2023, 116600
Zigui-Yichong-Fang protects against cyclophosphamide-induced premature ovarian insufficiency via the SIRT1/Foxo3a pathway
Zi Xiu a,1, Siling Tang a,1, Peng Kong b, Mengxuan Yan a, Xue Tong a, Xueping Liu a, Xiao Liang a, Rongxia Li a,c, Yancang Duan
doi : 10.1016/j.jep.2023.116608
Volume 314, 5 October 2023, 116608
Marsdenia tenacissima extract induces endoplasmic reticulum stress-associated immunogenic cell death in non-small cell lung cancer cells through targeting AXL
Yuan Yuan, Yang Guo, Zheng-Wang Guo, Hui-Feng Hao, Yan-Na Jiao, Xin-Xin Deng, Shu-Yan Han
doi : 10.1016/j.jep.2023.116620
Volume 314, 5 October 2023, 116620
Oral administration of Turnera diffusa willd. ex Schult. extract ameliorates steroidogenesis and spermatogenesis impairment in the testes of rats with type-2 diabetes mellitus
Gowri Gopa Kumar a, Eswar Kumar Kilari b, Giribabu Nelli a,**, Naguib Bin Salleh
doi : 10.1016/j.jep.2023.116638
Volume 314, 5 October 2023, 116638
Insight of “Yin-Jing� medical property of Ligusticum chuanxiong Hort. via pharmacokinetics and tissue distributions by ultra-performance liquid chromatography-triple quadrupole mass spectrometry
Xin Yu 1, Jun-Hong Chai 1, Xiang-Wen Kong, Chen-Xi Bai, Jun Liang, Hai-Xue Kuang **, Yong-Gang Xia
doi : 10.1016/j.jep.2023.116569
Volume 314, 5 October 2023, 116569
Tong Sai granule improves AECOPD via regulation of MAPK-SIRT1-NF-κB pathway and cellular senescence alleviation
Liuying Tao a,b,1, Xiaofan Lu a,b,1, Zijian Fu a,b, Yange Tian a,b,c, Xinguang Liu a,b,c, Jiansheng Li a,b,d, Peng Zhao
doi : 10.1016/j.jep.2023.116622
Volume 314, 5 October 2023, 116622
The potential of lemon balm (Melissa officinalis L.) essential oil as an anti-anxiety agent – is the citronellal the activity carrier?
Nikola M. Stojanovi´c a,*, Marko Z. Mladenovi´c b, Pavle J. Randjelovi´c a, Niko S. Radulovi´c
doi : 10.1016/j.jep.2023.116661
Volume 314, 5 October 2023, 116661
Astragalus polysaccharide alleviates alcoholic-induced hepatic fibrosis by inhibiting polymerase I and transcript release factor and the TLR4/JNK/NF-κB/MyD88 pathway
Xu Sun a,1, Yongqiu Zheng b,**,1, Yaqing Tian b,1, Qixiang Xu b, Shuochuan Liu a, Huahua Li a, Kunming Cheng b, Jianan Yuan b, Huaimin Liu a,***, Peng Zhu
doi : 10.1016/j.jep.2023.116662
Volume 314, 5 October 2023, 116662
BmKK2, a thermostable Kv1.3 blocker from Buthus martensii Karsch (BmK) scorpion, inhibits the activation of macrophages via Kv1.3-NF-κB- NLRP3 axis
Zhiheng Wang a,1, Ming Sang a,1, Yuxin Zhang b, Shengjun Chen c, Song Li c, Yonggen Chen b, Erjin Xu a, Qian Zhou a, Wenhao Xu b, Chenglei Zhao a, Dawei Wang a, Wuguang Lu a,b,**, Peng Cao
doi : 10.1016/j.jep.2023.116624
Volume 314, 5 October 2023, 116624
Research on the effectiveness and material basis of Ligusticum chuanxiong in alleviating acute liver injury
Lingzhi Lu a,1, Taotao Lu a,1, Yajing Wu a, Yunhong Wang b, Xiumei Ke c,*, Rongping Yang
doi : 10.1016/j.jep.2023.116643
Volume 314, 5 October 2023, 116643
Pharmacokinetics integrated with network pharmacology to clarify effective components and mechanism of Wendan decoction for the intervention of coronary heart disease
Pei Lin a,b,1, Liufang Hu a,b,1, Qiaoting Huang a, Yezi Zhang a, Zifei Qin c, Jiaxu Chen b, Xinsheng Yao a, Huanlin Wu d, Zhihong Yao a,b,*, Danping Xu
doi : 10.1016/j.jep.2023.116669
Volume 314, 5 October 2023, 116669
Zi-Su-Zi decoction improves airway hyperresponsiveness in cough-variant asthma rat model through PI3K/AKT1/mTOR, JAK2/STAT3 and HIF-1α/NF-κB signaling pathways
Vietdung Nguyen a,1, Qing Zhang a,1, Fei Pan b,1, Qi Jin b, Meng Sun a, Jakkree Tangthianchaichana a,c, Shouying Du a,**, Yang Lu
doi : 10.1016/j.jep.2023.116637
Volume 314, 5 October 2023, 116637
Fu-Zheng-Tong-Luo formula promotes autophagy and alleviates idiopathic pulmonary fibrosis by controlling the Janus kinase 2/signal transducer and activator of transcription 3 pathway
10.1016/j.jep.2023.116633
doi : 10.1016/j.jep.2023.116633
Volume 314, 5 October 2023, 116633
Cytostatic and cytotoxic effects of a hot water and methanol extract of Acokanthera oppositifolia in HepG2 hepatocarcinoma cells
Werner Cordier a,*, Paul Steenkamp b, Vanessa Steenkamp
doi : 10.1016/j.jep.2023.116617
Volume 314, 5 October 2023, 116617
Pharmacognostic profiles, evaluation of analgesic, anti-inflammatory and anticonvulsant activities of Newbouldia laevis (P. Beauv.) Seem. ex Bureau leaf and root extracts in Wistar rats
Cletus Anes Ukwubile a,*, Emmanuel Oise Ikpefan b, Musa Yusuf Dibal a, Vivian Amarachukwu Umeano c, David Nnamdi Menkiti d, Clement Chidi Kaosi e, Simon Paul f, Ademola Clement Famurewa g, Henry Nettey h, Timothy Samuel Yerima
doi : 10.1016/j.jep.2023.116632
Volume 314, 5 October 2023, 116632
Integrated network pharmacology, transcriptomics, and metabolomics analysis to reveal the mechanism of salt Eucommiae cortex in the treatment of chronic kidney disease mineral bone disorders via the PPARG/AMPK signaling pathway
Jie Shen a,b, Youping Liu a,*, Qin Wang b, Hongping Chen a, Yuan Hu a, Xiaohong Guo b, Xia Liu b, Yanhui Li
doi : 10.1016/j.jep.2023.116590
Volume 314, 5 October 2023, 116590
Application of omics technology to investigate the mechanism underlying the role of San Hua Tang in regulating microglia polarization and blood-brain barrier protection following ischemic stroke
Shan Luo a,b, Yuanchun Chen a, Ruoxi Zhao a, Donglai Ma c, Yanmeng Zhao d, Ying Zhang d,e, Jianming Jiang c,**, Wentao Yu
doi : 10.1016/j.jep.2023.116640
Volume 314, 5 October 2023, 116640
Coptisine inhibits Helicobacter pylori and reduces the expression of CagA to alleviate host inflammation in vitro and in vivo
Qin Tang a, Zhengcai Ma b, Xiang Tang b, Yan Liu a, Huimin Wu a, Yu Peng a, Baihua Jiao a, Rui Wang a, Xiaoli Ye b,**, Hang Ma a,***, Xuegang Li
doi : 10.1016/j.jep.2023.116618
Volume 314, 5 October 2023, 116618
Pfaffia glomerata polyploid accession compromises male fertility and fetal development
Fernanda C.R. Dias a, S´ergio L.P. Matta b, Graziela D.A. Lima b, Ana Cl´audia F. Souza c, Tatiana P. Menezes b, Fabiana C.S.A. Melo d, Wagner C. Otoni e, Mariana Machado Neves b, Marcos L.M. Gomes
doi : 10.1016/j.jep.2023.116680
Volume 314, 5 October 2023, 116680
Exploring the chondroprotective effect of Chaenomeles speciosa on Glucose-6-Phosphate Isomerase model mice using an integrated approach of network pharmacology and experimental validation
Zhihao Duan a,b,1, Can Jin b,1, Ying Deng b, Jinlang Liu a, Chengyi Gu a, Jie Wang a, Xiangquan Cai a, Shigang Li b,*,2, You Zhou
doi : 10.1016/j.jep.2023.116553
Volume 314, 5 October 2023, 116553
Integrating UPLC-Q-Exactive Orbitrap/MS, network pharmacology and experimental validation to reveal the potential mechanism of Tibetan medicine Rhodiola granules in improving myocardial ischemia-reperfusion injury
Nan Xing a,1, Jing Qin b,1, Dongsheng Ren c,1, Qinyun Du a, Yuying Li c, Jiao Mi c, Fengming Zhang c, Li Ai b, Sanyin Zhang d,e,**, Yi Zhang b,***, Shaohui Wang b,*
doi : 10.1016/j.jep.2023.116572
Volume 314, 5 October 2023, 116572
