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Traditional uses, phytochemistry, pharmacology, toxicology, and quality control of Rhododendron dauricum L. leaves: A comprehensive review
Qian Liang a, Jia-Xin Hu a, Xin-Min Zhang c, Wen-Hui Xu
doi : 10.1016/j.jep.2022.116085
Volume 305, 6 April 2023, 116085
Ethnomedicines for the treatment of scorpion stings: A perspective study
Susmita Nath a,b, Ashis K. Mukherjee
doi : 10.1016/j.jep.2022.116078
Volume 305, 6 April 2023, 116078
Research progress of Astragalus membranaceus in treating peritoneal metastatic cancer
Zhiyuan Li b, Jinfeng Qi b, Tiankang Guo a, Junliang Li
doi : 10.1016/j.jep.2022.116086
Volume 305, 6 April 2023, 116086
Ethnobotany, botany, phytochemistry and ethnopharmacology of the genus Thalictrum L. (Ranunculaceae): A review
Harsh Singh a,*, Dharmendra Singh b, Manoj M. Lekhak
doi : 10.1016/j.jep.2022.115950
Volume 305, 6 April 2023, 115950
Role of herbal medicine and gut microbiota in the prevention and treatment of obesity
Qiao Zhang a,*, Yaya Bai a, Wenxiao Wang a, Jiajia Li a, Li Zhang b, Yuping Tang a, Shijun Yue
doi : 10.1016/j.jep.2022.116127
Volume 305, 6 April 2023, 116127
Processing methods and the underlying detoxification mechanisms for toxic medicinal materials used by ethnic minorities in China: A review
Zi-Ge Feng a,b, Xia-Dao Cai-Rang a, Xiao-Yan Tan c, Cong-Ying Li a, Shang-Yu Zeng a, Yue Liu a,*, Yi Zhang
doi : 10.1016/j.jep.2022.116126
Volume 305, 6 April 2023, 116126
Preparation methods, structural characteristics, and biological activity of polysaccharides from Salvia miltiorrhiza: A review
Yuanyuan Li a, Xin Zhang a, Yining Li a, Pei Yang a, Zhiyuan Zhang a, Hang Wu b, Lihao Zhu c, Yuhong Liu
doi : 10.1016/j.jep.2022.116090
Volume 305, 6 April 2023, 116090
Research progress of natural medicine Astragalus mongholicus Bunge in treatment of myocardial fibrosis☆
Chunzhen Ren a,b,c, Xinke Zhao b,c,d, Kai Liu a,b,c, Lirong Wang a,b,c, Qilin Chen a,b,c, Hugang Jiang a,b,c, Xiang Gao a,b,c,d, Xinfang Lv a,b,c,d, Xiaodong Zhi a,b,c,d, Xue Wu a,b,c,e, Yingdong Li
doi : 10.1016/j.jep.2022.116128
Volume 305, 6 April 2023, 116128
The African cherry: A review of the botany, traditional uses, phytochemistry, and biological activities of Prunus africana (Hook.f.) Kalkman
Emmanuel Rubegeta a, Felix Makolo a, Guy Kamatou a, Gill Enslin a, Sushil Chaudhary a, Maxleene Sandasi a,b, Anthony B. Cunningham c, Alvaro Viljoen
doi : 10.1016/j.jep.2022.116004
Volume 305, 6 April 2023, 116004
Ardisia gigantifolia stapf (Primulaceae): A review of ethnobotany, phytochemistry, pharmacology, clinical application, and toxicity
Tian-Liang a,b, Xi-Gu-Ri-Gan a, Jiaoneng Yu a, Songbo Qu a,c, Qiaohui Xie a, Ribu Shama a, Mulan Bao a, Hongxin Su b, Bo Liu a,b,**, Almaz Borjigidai
doi : 10.1016/j.jep.2022.116079
Volume 305, 6 April 2023, 116079
Extraction, structure and bioactivities of polysaccharides from Rehmannia glutinosa: A review
Zhiying Bian a, Rui Zhang a, Xin Zhang a, Jingyi Zhang a, Lingchuan Xu a,b, Lihao Zhu c, Yan Ma a,**, Yuhong Liu
doi : 10.1016/j.jep.2022.116132
Volume 305, 6 April 2023, 116132
Analysis of the mechanism of Buyang Huanwu Decoction against cerebral ischemia-reperfusion by multi-omics
Huifen Zhou a,1, Bingying Lin a,1, Jiehong Yang a, Xiaoyu Wei a, Wei Fu b, Zhishan Ding a, Yu He a,**, Haitong Wan
doi : 10.1016/j.jep.2022.116112
Volume 305, 6 April 2023, 116112
Berberine hydrochloride inhibits migration ability via increasing inducible NO synthase and peroxynitrite in HTR-8/SVneo cells
Li-Jun Yang a,b,1, Jia-Bei He a,b,1, Yu Jiang c,1, Jianzhong Li d, Zhen-Wei Zhou a,b, Chuan Zhang e, Xia Tao c, Alex F. Chen b,***, Cheng Peng a,b,**, He-Hui Xie
doi : 10.1016/j.jep.2022.116087
Volume 305, 6 April 2023, 116087
Mechanisms of JinHong Formula on treating sepsis explored by randomized controlled trial combined with network pharmacology
Xinxin Wu a,1, Chenming He b,1, Changya Liu c,1, Xiangru Xu c, Caiyu Chen c, Hongqiang Yang c, Haimei Shi c, Yuerong Fei c, Yuting Sun c, Shuang Zhou d,**, Bangjiang Fang
doi : 10.1016/j.jep.2022.116040
Volume 305, 6 April 2023, 116040
Paiteling induces apoptosis of cervical cancer cells by down-regulation of the E6/E7-Pi3k/Akt pathway: A network pharmacology
doi : 10.1016/j.jep.2022.116062
Volume 305, 6 April 2023, 116062
Tanreqing injection protects against bleomycin-induced pulmonary fibrosis via inhibiting STING-mediated endoplasmic reticulum stress signaling pathway
doi : 10.1016/j.jep.2022.116071
Volume 305, 6 April 2023, 116071
Integrative transcriptomics and proteomics analyses to reveal the therapeutic effect and mechanism of Buxue Yimu Pills in medical-induced incomplete abortion rats
doi : 10.1016/j.jep.2022.116113
Volume 305, 6 April 2023, 116113
Water extract of Notopterygium incisum alleviates cold allodynia in neuropathic pain by regulation of TRPA1
Yonglan Ruan 1, Xiang Jin 1, Haiwang Ji , Chan Zhu , Yan Yang , Yuan Zhou , Guang Yu , Changming Wang *, Zongxiang Tang
doi : 10.1016/j.jep.2022.116065
Volume 305, 6 April 2023, 116065
Investigations of plausible pharmacodynamics supporting the antispasmodic, bronchodilator, and antidiarrheal activities of Berberis lycium Royle. Via in silico, in vitro, and in vivo studies
Syed Adil Hussain Shah, Ambreen Aleem
doi : 10.1016/j.jep.2022.116115
Volume 305, 6 April 2023, 116115
Multi-omics and network pharmacology study reveals the effects of Dengzhan Shengmai capsule against neuroinflammatory injury and thrombosis induced by ischemic stroke
Ji Ye a,1, Fan Huang b,1, Huawu Zeng a, Xike Xu a, Gaosong Wu b, Saisai Tian a,*, Jing Zhao b,**, Weidong Zhang
doi : 10.1016/j.jep.2022.116092
Volume 305, 6 April 2023, 116092
Untargeted metabolomics reveals the combination effects and mechanisms of Huangqi-fuzi herb-pair against doxorubicin-induced cardiotoxicity
Zhen Xue a,b,1, Lingxin Zhuo a,b,1, Bowen Zhang a,b, Lingmeng Zhu a,b, Xinran Xiang a,b, Chunxia Zhang a,b, Wenyuan Liu a,c,**, Guangguo Tan d,***, Wenting Liao
doi : 10.1016/j.jep.2022.116109
Volume 305, 6 April 2023, 116109
Integrated network pharmacology and experimental verification to explore the molecular mechanism of Jingxin Zhidong formula for treating Tic disorder
Xue Tian a, Guangyin Ou b,c, Shaopu Hu b,c, Chunhui Wang a, Fei Han a,**, Lei Gao
doi : 10.1016/j.jep.2022.116114
Volume 305, 6 April 2023, 116114
Xiangshao Granules reduce the aggressive behavior and hippocampal injury of premenstrual irritability in rats by regulating JIK/JNK/p38 signal pathway
Shujing Li a, Xiangyu Mu a, Sufen Ma b, Xin Li c, Jie Gao a, Xiaoju Liu a, Haijuan Wang d, Junling Wu e, Yinghui Guo a,*, Chunhong Song
doi : 10.1016/j.jep.2022.116061
Volume 305, 6 April 2023, 116061
Active ingredients screening and pharmacological mechanism research of curcumae rhizoma-sparganii rhizoma herb pair ameliorates liver fibrosis based on network pharmacology
doi : 10.1016/j.jep.2022.116111
Volume 305, 6 April 2023, 116111
Gastroprotective effect methanol extract of Caesalpinia coriaria pods against indomethacin- and ethanol-induced gastric lesions in Wistar rats
doi : 10.1016/j.jep.2022.116057
Volume 305, 6 April 2023, 116057
Effect and mechanism of safranal on ISO-induced myocardial injury based on network pharmacology
Meijuan Yan a,b,c,1, Jichuan Zhao a,b,c,1, Yingjie Kang a,b,d,1, Luqian Liu a,b,c, Wenjun He a,b,c, Yufang Xie a,b,d, Rui Wang a,b,d, Liya Shan a,b,d,**, Xinzhi Li a,b,c,***, Ketao Ma
doi : 10.1016/j.jep.2022.116103
Volume 305, 6 April 2023, 116103
Exploration of the main effective constituent and the mechanism in Astragali Radix in the treatment for doxorubicin-induced nephropathy by integrating metabolomics and molecular docking
Aiping Li a,1, Wenbo Cui a,d,1, Yirui Zhao b, Tingting Luo a, Qingyu Zhang a, Yuetao Liu a, Ke Li a, Xuemei Qin a,*, Lichao Zhang
doi : 10.1016/j.jep.2022.116074
Volume 305, 6 April 2023, 116074
Terminalia bellirica ethanol extract ameliorates nonalcoholic fatty liver disease in mice by amending the intestinal microbiota and faecal metabolites
Boyu Zhang a, Xiaomin Luo a, Cairong Han a, Jingxian Liu a, Le Zhang a, Jin Qi b, Jian Gu a, Rui Tan c, Puyang Gong
doi : 10.1016/j.jep.2022.116082
Volume 305, 6 April 2023, 116082
An integrated strategy to study the combination mechanisms of Bupleurum chinense DC and Paeonia lactiflora Pall for treating depression based on correlation analysis between serum chemical components profiles and endogenous metabolites profiles
Congcong Chen a,b, Junshen Tian a,b, Xiaoxia Gao a,b, Xuemei Qin a,b, Guanhua Du a,c, Yuzhi Zhou
doi : 10.1016/j.jep.2022.116068
Volume 305, 6 April 2023, 116068
Evaluation of genotoxicity and 13-week subchronic toxicity of root of Asarum heterotropoides var. seoulense (Nakai) Kitag
Eun-Young Gu a,b, Jina Jung b, Seng-Min Back b, Kwang-Hyun Lim b, Woojin Kim b, Byung Sun Min c, Kang-Hyun Han b, Sang Kyum Kim a,*, Yong-Bum Kim
doi : 10.1016/j.jep.2022.116012
Volume 305, 6 April 2023, 116012
Oral acute, sub-acute toxicity and phytochemical profile of Brassica carinata A. Braun microgreens ethanolic extract in Wistar rats
Lilian Nakakaawa a,*, Ifeoluwa D. Gbala a, Xavier Cheseto b, Joel L. Bargul b,c, John M. Wesonga
doi : 10.1016/j.jep.2022.116121
Volume 305, 6 April 2023, 116121
Simiao Yong'an decoction ameliorates murine collagen-induced arthritis by modulating neutrophil activities: An in vitro and in vivo study
Shan-shan Jie a,1, Hui-juan Sun a,1, Jian-xin Liu a, Yan Gao b, Dong Bai a, Liu-luan Zhu c, Hong-yan Zhao d, Hui Zeng b,*, Ya-luan Ma
doi : 10.1016/j.jep.2022.116119
Volume 305, 6 April 2023, 116119
Sophora flavescens Aiton methanol extract exerts anti-inflammatory effects via reduction of Src kinase phosphorylation
Jieun Oh a, Seung A. Kim a, Ki Woong Kwon a, Se Rin Choi b, Choong Hwan Lee b, Mohammad Amjad Hossain c, Eun Sil Kim d, Changmu Kim d, Byoung-Hee Lee d, Sarah Lee d,***, Jong-Hoon Kim c,**, Jae Youl Cho
doi : 10.1016/j.jep.2022.116015
Volume 305, 6 April 2023, 116015
Curcuminoids inhibit human and rat placental 3β-hydroxysteroid dehydrogenases: Structure-activity relationship and in silico docking analysis
Jianmin Sang a, Jinjin Chu a, Xin Zhao a, Hehua Quan a, Zhongyao Ji a, Shaowei Wang b, Yunbing Tang b, Zhiyan Hu a, Huitao Li a, Linxi Li a,**, Ren-shan Ge
doi : 10.1016/j.jep.2022.116051
Volume 305, 6 April 2023, 116051
In vitro and in vivo anti-osteoarthritis effects of tradition Chinese prescription Ji-Ming-San
Cheng-Yang Hsieh a, Ching-Chiung Wang a,b,c,d, Lemmuel L. Tayo e, Shun-Xin Deng a, Po-Wei Tsai f, Chia-Jung Lee
doi : 10.1016/j.jep.2022.116084
Volume 305, 6 April 2023, 116084
Chemical characterization, anti-nociceptive and anti-inflammatory activities of Plukenetia conophora seed oil in experimental rodent models
Abayomi M. Ajayi a,*, Christie B. Ola a, Maduka B. Ezeagu a, Paul A. Adeleke a, Kayode A. John a, Mary O. Ologe c, Benneth Ben-Azu b, Solomon Umukoro
doi : 10.1016/j.jep.2022.116017
Volume 305, 6 April 2023, 116017
Prinsepia utilis Royle leaf extract: Ameliorative effects on allergic inflammation and skin lesions in allergic contact dermatitis and polyphenolic profiling through UPLC–MS/MS coupled to chemometric analysis
Wei Shen a, Si-Yuan Li a, Yu-Qing Pan a, Hao Liu a, Xiao-Wei Dong a, Xiao-Qi Zhang b, Wen-Cai Ye b, Xiao-Long Hu a,**, Hao Wang
doi : 10.1016/j.jep.2022.116093
Volume 305, 6 April 2023, 116093
Jiawei Taohe Chengqi Decoction attenuates hepatic fibrosis by preventing activation of HSCs through regulating Src/ERK/Smad3 signal pathway
Yan Huang, Zhi-Li Wang, Yi He, Lin-Mao Ye, Wen-Qin Guo, Jun-Jie Zhang
doi : 10.1016/j.jep.2022.116059
Volume 305, 6 April 2023, 116059
The San-Qi-Xue-Shang-Ning formula protects against ulcerative colitis by restoring the homeostasis of gut immunity and microbiota
Wei Yu, Cai Kang, Yijia Zhang, Qi Li, Zhiqiang Zhang, Yang Zheng, Xincheng Liu, Jing Yan
doi : 10.1016/j.jep.2022.116125
Volume 305, 6 April 2023, 116125
The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway
Lian-Chun Li 1, Yu-Xia Fu 1, De-Sheng Ning 1, Ling-Ling Yu, Zhi-Qi Zou, Zheng-Hong Pan
doi : 10.1016/j.jep.2022.116124
Volume 305, 6 April 2023, 116124
Interventional effect of processing temperature on anti-angiogenesis of Coptis chinensis and screening of active components by UPLC-MS/MS on quail chick chorioallantoic membrane model
Dan Wang 1, Miao Qi 1, Hedi Zhao , Haozhong Wu , Han Chen , Yanan Lan , Yanmin Wang , Yani Jiang , Jingjuan Wang
doi : 10.1016/j.jep.2022.116014
Volume 305, 6 April 2023, 116014
Si–Ni-San improves experimental colitis by favoring Akkermensia colonization
Yajie Cai a,1, Xiaojiaoyang Li b,1, Qi Han b,1, Jinzhao Bai a, Qi Zheng a, Rong Sun c, Runping Liu
doi : 10.1016/j.jep.2022.116067
Volume 305, 6 April 2023, 116067
Moringa oleifera impedes protein glycation and exerts reno-protective effects in streptozotocin-induced diabetic rats
Shadab Ahmad a,c, Alka Raj Pandey b,c, Amit K. Rai a, Suriya P. Singh b, Pawan Kumar a,c, Sushmita Singh a,c, Farah Gulzar a, Ishbal Ahmad a, Koneni V. Sashidhara b,c, Akhilesh K. Tamrakar a
doi : 10.1016/j.jep.2022.116117
Volume 305, 6 April 2023, 116117
Saikosaponins ameliorate hyperlipidemia in rats by enhancing hepatic lipid and cholesterol metabolism
Qi Zheng a,1, Xiaojiaoyang Li b,1, Nana Huang c, Fanghong Li a, Junde Ge c, Daijie Wang d, Rong Sun c,**, Runping Liu
doi : 10.1016/j.jep.2022.116110
Volume 305, 6 April 2023, 116110
Total flavonoids of Litchi seed attenuate stem cell-like properties in breast cancer by regulating Notch3 signaling pathway
Yunnuo Liao a,b,1, Zhuo Luo a,1, Ying Liu b,c,1, Wei Xue a,d, Songhua He e, Xin Chen a,b, Hong Ren b,f, Xin Yang b, Dan Zhu a, Zhiheng Su a,***, Qiuju Huang a,**, Hongwei Guo
doi : 10.1016/j.jep.2023.116133
Volume 305, 6 April 2023, 116133
Potential anti-gout properties of Wuwei Shexiang pills based on network pharmacology and pharmacological verification
Lijie Bai a, Chen Wu a, Shuhui Lei a, Min Zou a, Shengjun Wang b, Zhongyun Zhang a, Zilu Bao a, Zhaoxiang Ren a, Kaiqun Liu a, Qianjiao Ma a, Hongyue Ou a, Zhou Lan c,**, Qian Wang d,***, Lvyi Chen
doi : 10.1016/j.jep.2023.116147
Volume 305, 6 April 2023, 116147
Effects of two Ayurvedic formulations, Dhanwantaram Kashaya and Saraswatarishta on life history parameters and toxic aggregates in Drosophila models of Huntington’s and Alzheimer's disease
Swati Sharma a, Girish Singh b, Kishor Patwardhan
doi : 10.1016/j.jep.2022.116080
Volume 305, 6 April 2023, 116080
Water extract from Herpetospermum pedunculosum attenuates oxidative stress and ferroptosis induced by acetaminophen via regulating Nrf2 and NF-κB pathways
Jintao Li a,c,f,1, Qiuxia Lu a,d,f,1, Meihao Peng a,c,f, Jiaqing Liao a,c,f, Bowen Zhang a,d,f, Di Yang a,d,f, Peng Huang g, Yixi Yang a,d,f, Qi Zhao a,d,f, Bo Han b,**, Jian Li
doi : 10.1016/j.jep.2022.116069
Volume 305, 6 April 2023, 116069
miRNA-15/IL-10Rα axis promotes Kabasura Kudineer (Indian traditional Siddha formulation) induced immunomodulation by suppressing oxidative stress
Jyotirmaya Behera a,1, M. Pitchiah Kumar b,1, A. Ireen Femela a, Govindan Senguttuvan c, M.S. Ramasamy
doi : 10.1016/j.jep.2022.116032
Volume 305, 6 April 2023, 116032
Evaluation of You-Gui-Wan critical compounds inhibiting ALOX-5 and HDC gene expression in RBL-2H3 cells using a fractional factorial design
Po-Ting Chen a, Pei-Chi Chen b, Jiu-Yao Wang b,c, Shulhn-Der Wang d,**, Li-Jen Lin
doi : 10.1016/j.jep.2022.116122
Volume 305, 6 April 2023, 116122
Antioxidant and anti-inflammatory potential of rhizome aqueous extract of sea holly (Eryngium maritimum L.) on Jurkat cells
Iv´an Cort´es-Fern´andez a, Antoni Sureda b,c,d,*, Miquel Adrover e, Giovanni Caprioli f, Filippo Maggi f, Lorenzo Gil-Vives a, Xavier Cap´o
doi : 10.1016/j.jep.2022.116120
Volume 305, 6 April 2023, 116120
In vitro tests to evaluate embryotoxicity and irritation of Chinese herbal medicine (Pentaherbs formulation) for atopic dermatitis
Lu Li a,b,c,d,e,f,1, Xuan Mou a,b,1, Hongliang Xie a,b,1, Aolin Zhang a,b, Junwei Li a,b, Rongyun Wang g, Andr´e Seid h, Ling Yin Tang e, Ling Wang i, Ping Chung Leung f, Horst Spielmann h,**, Chi Chiu Wang e,g,***, Xiaohui Fan
doi : 10.1016/j.jep.2023.116149
Volume 305, 6 April 2023, 116149
Effects of Tylophora yunnanensis Schltr on regulating the gut microbiota and its metabolites in non-alcoholic steatohepatitis rats by inhibiting the activation of NOD-like receptor protein 3
Yu-ping Lin a,b,1, Qiong-lian Fang b,1, Yong-mei Xue b, Sheng-nan Fu b, Chun-Yan Hu b, Feng Huang b, Meng-meng Wang b, Xue Qiao b, Xun-qing Yin b, Yong-cheng Zeng b, Cheng-hong Du b, Xiu-juan Zhao b, Xin-ping Li b,c,**, Yan Hua
doi : 10.1016/j.jep.2023.116145
Volume 305, 6 April 2023, 116145
Si-Ni-San reduces lipid droplet deposition associated with decreased YAP1 in metabolic dysfunction–associated fatty liver disease
Kangning Zheng a, Wenhan Zhou a, Jingmin Ji b, Yu Xue b, Yiwei Liu b, Caige Li b, Zhiqin Zhang b, Junlan Lu b, Xinli Shi b,**, Yongmin Li
doi : 10.1016/j.jep.2022.116081
Volume 305, 6 April 2023, 116081
Chai-Gui Decoction and its representative components ameliorate spontaneous hypertension rats by modulating lipid metabolism and gut microbiota
Hongjun Zhu a, Chen Xu a, Yun Dong a, Shu Lu a, Linxiu Guo
doi : 10.1016/j.jep.2022.116116
Volume 305, 6 April 2023, 116116
Established UPLC-MS/MS procedure for multicomponent quantitative analysis of rat plasma: Pharmacokinetics of Taohong Siwu Decoction in normal and acute blood stasis models
Xinrui Wang a,b,1, Jianzhong Lu a,b,1, Guotong Li a,b, Lifei Luo b, Zhen Yuan b, Min Li c, Jingze Zhang a,b, Dailin Liu
doi : 10.1016/j.jep.2022.116094
Volume 305, 6 April 2023, 116094
Drug vector representation and potential efficacy prediction based on graph representation learning and transcriptome data: Acacetin from traditional Chinese Medicine model
Jian-Ping Deng a,b,c, Xin Liu a,b,c, Yue Li a,b,c, Shi-Hao Ni a,b,c, Shu-Ning Sun a,b,c, Xiao-Lu Ou-Yang a,b,c, Xiao-Han Ye d,**,1, Ling-Jun Wang a,b,c,***,1, Lu Lu
doi : 10.1016/j.jep.2022.115966
Volume 305, 6 April 2023, 115966
Antinociceptive effect and identification of berberine alkaloid in Berberis ruscifolia extracts
Micaela Paula Del Gaudio a,b, Scheila Iria Kraus c, Tayza Martins Melzer c, Pamela Soledad Bustos a,b, Mar?a Gabriela Ortega
doi : 10.1016/j.jep.2022.116066
Volume 305, 6 April 2023, 116066
