Journal of Ethnopharmacology




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Editorial Board

doi : 10.1016/S0378-8741(22)00946-1

Volume 301, 30 January 2023, 115907

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Recent advances of traditional Chinese medicine for the prevention and treatment of atherosclerosis

Wenbing Zhi a, Yang Liu a, Xiumei Wang b,**, Hong Zhang

doi : 10.1016/j.jep.2022.115749

Volume 301, 30 January 2023, 115749

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Nephroprotective plant species used in traditional Mayan Medicine for renal-associated diseases

Rodrigo Casta?neda a,*, Armando C´aceres b, Sully M. Cruz a, J. Agust?n Aceituno a, E. Sebasti´an Marroqu?n a, Ana C. Barrios Sosa c, Wendy K. Strangman c, R. Thomas Williamson

doi : 10.1016/j.jep.2022.115755

Volume 301, 30 January 2023, 115755

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A review: Pharmacokinetics and pharmacology of aminoalcohol-diterpenoid alkaloids from Aconitum species

Honglin Tao a,1, Xianfeng Liu a,1, Ruimin Tian a, Yue Liu b, Yong Zeng a,*, Xianli Meng a,c,**, Yi Zhang

doi : 10.1016/j.jep.2022.115726

Volume 301, 30 January 2023, 115726

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A scoping review of African natural products against gastric ulcers and Helicobacter pylori

S. Dinat, A. Orchard, S. Van Vuuren

doi : 10.1016/j.jep.2022.115698

Volume 301, 30 January 2023, 115698

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Progress on the role of traditional Chinese medicine in therapeutic angiogenesis of heart failure

Chennan Wu a,1, Fei Chen a,1, Si Huang a, Zhen Zhang a, Jingjing Wan a, Weidong Zhang a,b,**, Xia Liu

doi : 10.1016/j.jep.2022.115770

Volume 301, 30 January 2023, 115770

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Ligustri Lucidi Fructus, a traditional Chinese Medicine: Comprehensive review of botany, traditional uses, chemical composition, pharmacology, and toxicity

Mayijie Cao 1, Jie Wu 1, Ying Peng , Baohua Dong , Yunxiu Jiang , Changjiang Hu , Lingying Yu **, Zhimin Chen

doi : 10.1016/j.jep.2022.115789

Volume 301, 30 January 2023, 115789

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Crataegus pinnatifida: A botanical, ethnopharmacological, phytochemical, and pharmacological overview

Ruiyu Li a,b,1, Fei Luan a,1, Yunyan Zhao a, Mengyao Wu a, Yang Lu a, Chengtian Tao a, Lv Zhu a, Chi Zhang b,**, Li Wan

doi : 10.1016/j.jep.2022.115819

Volume 301, 30 January 2023, 115819

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Ethnopharmacological use, pharmacology, toxicology, phytochemistry, and progress in Chinese crude drug processing of the lateral root of Aconitum carmichaelii Debeaux. (Fuzi): A review

Meng Wang a,*, Wen-Jing Hu a, Xiao Zhou a, Kuo Yu b, Yan Wang b, Bing-You Yang a, Hai-Xue Kuang

doi : 10.1016/j.jep.2022.115838

Volume 301, 30 January 2023, 115838

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Molecular mechanism of the anti-inflammatory effects of plant essential oils: A systematic review

Qian Zhao a, Liyun Zhu a,b,*, Sunan Wang c, Yongsheng Gao a,b, Fei Jin

doi : 10.1016/j.jep.2022.115829

Volume 301, 30 January 2023, 115829

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Celastrus orbiculatus Thunb. extract inhibits EMT and metastasis of gastric cancer by regulating actin cytoskeleton remodeling

Haibo Wang a,b,1,*, YuanYuan Luo a,1, Shiya Ou a,b,1, Tengyang Ni a,b, Zewen Chu a,b, Xinyi Feng a,b, Xiaojun Dai b,c, Xiaochun Zhang a,b,c,**, Yanqing Liu a,b

doi : 10.1016/j.jep.2022.115737

Volume 301, 30 January 2023, 115737

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Antithrombotic potential of Lippia alba: A mechanistic approach

Paula M. Leite a,*, Ana P.N. Miranda a, Izabella Gomes a, Maria L. Rodrigues a, Layla M. Camargos a, Juliana M. Amorim a, Rita C.F. Duarte b, Andr´e A.G. Faraco a, Maria G. Carvalho b, Rachel O. Castilho

doi : 10.1016/j.jep.2022.115744

Volume 301, 30 January 2023, 115744

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Seeds of Ginkgo biloba L. inhibit oxidative stress and inflammation induced by cigarette smoke in COPD rats through the Nrf2 pathway

Yiyun Qian a, Liang Yan b, Min Wei a,*, Pingping Song a, Lihong Wang

doi : 10.1016/j.jep.2022.115758

Volume 301, 30 January 2023, 115758

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Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway

Yanhui Zhu a,1, Qianqian Han b,1, Lei Wang a, Baiyan Wang b, Jianshuang Chen a, Bangrong Cai a, Can Wu a, Xiali Zhu a, Fugang Liu a, Deen Han a, Haoran Dong c, Yongyan Jia a,*, Yalin Liu

doi : 10.1016/j.jep.2022.115763

Volume 301, 30 January 2023, 115763

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A network pharmacology integrated pharmacokinetics strategy to investigate the pharmacological mechanism of absorbed components from crude and processed Zingiberis Rhizoma on deficiency-cold and hemorrhagic syndrome

Jiasheng Li a,1, Ying Zhang b,1, Shurui Liu c,1, Wangjun Li a,1, Yue Sun a, Hui Cao b,**, Shumei Wang a,***, Jiang Meng

doi : 10.1016/j.jep.2022.115754

Volume 301, 30 January 2023, 115754

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Mesua assamica (King&Prain) kosterm. Bark ethanolic extract attenuates chronic restraint stress aggravated DSS-induced ulcerative colitis in mice via inhibition of NF-κB/STAT3 and activation of HO-1/Nrf2/SIRT1 signaling pathways

Eswara Rao Puppala a, Sai Sudha Yalamarthi a, Sunepjungla L. Aochenlar a, Neethu Prasad a, N.P. Syamprasad a, Meenakshi Singh b, Satheesh Kumar Nanjappan c, V. Ravichandiran c, Dinesh Mani Tripathi d, Jagadeesh Kumar Gangasani a,**, V.G.M. Naidu a,

doi : 10.1016/j.jep.2022.115765

Volume 301, 30 January 2023, 115765

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Iso-seco-tanapartholide from Artemisia argyi inhibits the PFKFB3-mediated glycolytic pathway to attenuate airway inflammation in lipopolysaccharide-induced acute lung injury mice

Min Kong a, Dongrong Zhu a,b, Junyi Dong a, Lingyi Kong a,**, Jianguang Luo

doi : 10.1016/j.jep.2022.115781

Volume 301, 30 January 2023, 115781

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Kunling Wan improves oocyte quality by regulating the PKC/Keap1/Nrf2 pathway to inhibit oxidative damage caused by repeated controlled ovarian hyperstimulation

Fengli Guan 1, Shuancheng Zhang 1, Lijie Fan , Ying Sun , Yucong Ma , Can Cao , Yu Zhang , Ming He **, Huilan Du

doi : 10.1016/j.jep.2022.115777

Volume 301, 30 January 2023, 115777

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Hypouricemic and nephroprotective effects of palmatine from Cortex Phellodendri Amurensis: A uric acid modulator targeting Keap1-Nrf2/NLRP3 axis

Gaoxiang Ai a,1, Ronglei Huang a,1, Jianhui Xie b,c,d, Linjiang Zhong a, Xiaoyan Wu a, Zehui Qin a, Ziren Su a, Jiannan Chen a, Xiaobo Yang b,c,d,**, Yaoxing Dou b,e,*

doi : 10.1016/j.jep.2022.115775

Volume 301, 30 January 2023, 115775

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Integrate metabolomics strategy and target prediction to reveal the ameliorate effect of four typical ‘cold’ property herbs on hyperthyroidism rats

Yangyang Wang a, Yanping Sun a, Bingyou Yang a, Qiuhong Wang b,**, Haixue Kuang

doi : 10.1016/j.jep.2022.115772

Volume 301, 30 January 2023, 115772

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Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin

Svetolik Maksimovic a,*, Milica Stankovic b, Sonja Roganovic b, Ivana Nesic b, Jelena Zvezdanovic c, Vanja Tadic d, Irena Zizovic

doi : 10.1016/j.jep.2022.115779

Volume 301, 30 January 2023, 115779

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Cytotoxicity and antimicrobial activity of isolated compounds from Monsonia angustifolia and Dodonaea angustifolia

Zenande K.S. Mcotshana a, Lyndy J. McGaw b, Douglas Kemboi a, Gerda Fouche d, Ibukun M. Famuyide b, Rui W.M. Krause c, Xavier Siwe-Noundou e, Vuyelwa Jacqueline Tembu

doi : 10.1016/j.jep.2022.115170

Volume 301, 30 January 2023, 115170

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Mechanism investigation of Shi-Xiao-San in treating blood stasis syndrome based on network pharmacology, molecular docking and in vitro/vivo pharmacological validation

Xing Wei 1, Mingliang Gao 1, Nian Sheng, Weifeng Yao , Beihua Bao , Fangfang Cheng , Yudan Cao , Hui Yan , Li Zhang , Mingqiu Shan **, Peidong Chen

doi : 10.1016/j.jep.2022.115746

Volume 301, 30 January 2023, 115746

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Protection of Taohong Siwu Decoction on PC12 cells injured by oxygen glucose deprivation/reperfusion via mitophagy-NLRP3 inflammasome pathway in vitro

Yun Shi a,1, Qing Liu a,1, Weidong Chen a,b,c,d,e, Ruirui Wang a, Lei Wang a,b,c,f, Zhu-qing Liu a, Xian-chun Duan a, Yanchun Zhang a, Aizong Shen g, Daiyin Peng a,b,c,d, Lan Han a,b,**, Zhaojie Ji

doi : 10.1016/j.jep.2022.115784

Volume 301, 30 January 2023, 115784

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Efficacies and side effects of medicinal plants used by patients with cancer in Morocco: A retrospective treatment-outcome study

Mohamed Aboufaras a,*, Karima Selmaoui a, Nadia Ouzennou

doi : 10.1016/j.jep.2022.115783

Volume 301, 30 January 2023, 115783

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The most bioactive fraction of stir-fried Radix Paeoniae Alba regulating IL-6/STAT3 signaling pathway in allergic asthma mouse

Xia’nan Sang a,1, Xuedong Wan a,1, Han Zhang b,1, Jialiang Ying a, Lu Wang a, Qiao Yang a, Qiyuan Shan a, Min Hao a, Minjing Qin a, Qitong Zheng a, Quan Chen a, Xin Han a,**, Gang Cao

doi : 10.1016/j.jep.2022.115821

Volume 301, 30 January 2023, 115821

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Therapeutic effect and underlying mechanism of Shenkang injection against cisplatin–induced acute kidney injury in mice

Jiahan Su a,b,1, Tingting He a,b,1, Jing You a,c, Jingjie Cao a, Qianru Wang a, Shousong Cao a, Qibing Mei a,b, Jing Zeng a,*, Li Liu

doi : 10.1016/j.jep.2022.115805

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Zerumbone, a major sesquiterpene from Syringa pinnatifolia Hemsl., exerts the sedative effect by regulating GABAergic nervous system

Shana Wuken a, Junjun Li a, Xiaoli Gao a, Shungang Jiao a, Xiaojing Ma a, Suyile Chen b, Pengfei Tu a, Luqi Huang c,**, Xingyun Chai

doi : 10.1016/j.jep.2022.115813

Volume 301, 30 January 2023, 115813

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Piperlongumine overcomes imatinib resistance by inducing proteasome inhibition in chronic myelogenous leukemia cells

Xiaoying Lan a,b,1, Min Hu a,1, Liling Jiang a,c,1, Jiamin Wang a,1, Yi Meng a, Xinmei Chen a, Aochu Liu a, Wa Ding a, Haichuan Zhang a, Huan Zhou a, Bingyuan Liu a, Guanjie Peng a, Siyan Liao a, Xin Chen a,*, Jinbao Liu a,**, Xianping Shi

doi : 10.1016/j.jep.2022.115815

Volume 301, 30 January 2023, 115815

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Safety evaluations of the processed lateral root of Aconitum carmichaelii Debx. And its hepatotoxicity mechanisms in rats

Xiaoyu Ji a, Mengbi Yang a,b, Guolin Shen c, Ka Hang Or d, Wan Sze Yim d, Zhong Zuo

doi : 10.1016/j.jep.2022.115801

Volume 301, 30 January 2023, 115801

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Exploring the nephrotoxicity of sulfur-containing derivatives in sulfur-fumigated Panacis Quinquefolii Radix based on chemical profiling and untargeted metabolomics

Jinjin He a, Jun Jiang a,d,*, Tong Xie b, Yuan Liu c, Hui Cai d, Shichang Xiao a, Zhihui Cai a, Tong Chen

doi : 10.1016/j.jep.2022.115773

Volume 301, 30 January 2023, 115773

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Kaempferol 3-O-rutinoside from Antidesma acidum Retz. Stimulates glucose uptake through SIRT1 induction followed by GLUT4 translocation in skeletal muscle L6 cells

Bhaswati Kashyap a,b, Kangkon Saikia c, Suman Kumar Samanta d, Debajit Thakur c, Sanjay Kumar Banerjee f,g, Jagat Chandra Borah a,**, Narayan Chandra Talukdar

doi : 10.1016/j.jep.2022.115788

Volume 301, 30 January 2023, 115788

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Proteomics reveals that Di Dang decoction can regulate the Jak2/Stat5 signaling pathway and inhibit apoptosis by reducing the oxidative stress response in rats with acute intracerebral hemorrhagic stroke

Lina Feng a, Xinyue Zhang b, Wei Li a, Jie Wang b, Qi Wang b, Qingwei Wang c, Mingquan Li

doi : 10.1016/j.jep.2022.115816

Volume 301, 30 January 2023, 115816

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Anti-cervical cancer effects of Compound Yangshe granule through the PI3K/AKT pathway based on network pharmacology

Chao Ma a, Yongwei Gu a, Chang Liu b, Xiaomeng Tang a, Jianchao Yu c, Dan Li a, Jiyong Liu

doi : 10.1016/j.jep.2022.115820

Volume 301, 30 January 2023, 115820

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Efficacy of curculigoside in protecting against ischemic brain injury through regulation of oxidative stress and NF-κB and PI3K/Akt expression

Yan Xu a,b, Kuo Wen c,1, Aijun Liu d, Xinna Wang c, Hanying Xu c, Hongjuan Wen

doi : 10.1016/j.jep.2022.115804

Volume 301, 30 January 2023, 115804

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Phytochemical characterization and anti-inflammatory activity of a water extract of Gentiana purpurea roots

Lin Zhang a, Emilie Steinbakk Ulriksen b, H?vard Hoel a, Lene Sandvik a, Karl Egil Malterud a, Kari Tvete Inngjerdingen a, Marit Inngjerdingen b, Helle Wangensteen

doi : 10.1016/j.jep.2022.115818

Volume 301, 30 January 2023, 115818

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Exploring the synergic mechanism of Ligusticum striatum DC. and borneol in attenuating BMECs injury and maintaining tight junctions against cerebral ischaemia based on the HIF-1α/VEGF signalling pathway

Xiaoxiong Song a, Wanqing Xing a, Xiaofeng Zhang a, Xueqing Wang a, Jing Ji a, Jinfu Lu a, Bin Yu a,*, Ming Ruan

doi : 10.1016/j.jep.2022.115764

Volume 301, 30 January 2023, 115764

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Mechanisms underpinning Carpolobia lutea G. Don ethanol extract's neurorestorative and antipsychotic-like activities in an NMDA receptor antagonist model of schizophrenia

Noah A. Omeiza a,*, Adewale Bakre a, Benneth Ben-Azu b, Abimbola A. Sowunmi a, Halimat A. Abdulrahim c, Joseph Chimezie d, Sodiq O. Lawal d, Olusegun G. Adebayo d,h, Abdullateef I. Alagbonsi e, Olugbenga Akinola f, Amos O. Abolaji g, Adegbuyi O. Aderibigbe

doi : 10.1016/j.jep.2022.115767

Volume 301, 30 January 2023, 115767

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Schinus terebinthifolia leaf lectin has central and peripheral antinociceptive action mediated by its carbohydrate-recognition domain and delta-opioid receptors

Amanda de Oliveira Marinho , J´essica de Santana Brito , Jainaldo Alves da Costa , Abdˆenego Rodrigues da Silva , Su´ellen Pedrosa da Silva , Luciclaudio Cassimiro de Amorim , Maria Tereza dos Santos Correia , Patr?cia Maria Guedes Paiva , Alisson Mac´ario de Oliveira , Leydianne Leite de Siqueira Patriota , Thiago Henrique Napole?ao

doi : 10.1016/j.jep.2022.115817

Volume 301, 30 January 2023, 115817

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Isolation & identification of anti-inflammatory constituents of Randia dumetorum lamk. fruit: Potential beneficial effects against acute lung injury

Arun Narota a, Ranjit Singh b, Ranju Bansal b, Ashwani Kumar b, Amarjit S. Naura

doi : 10.1016/j.jep.2022.115759

Volume 301, 30 January 2023, 115759

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Inhibition on XBP1s-driven lipogenesis by Qushi Huayu Decoction contributes to amelioration of hepatic steatosis induced by fructose

Huajie Tian a, Yi Fang a, Wei Liu a, Jun Wang a, Jianan Zhao a, Hao Tang a, Yixiao Yin a, Yiyang Hu b,c,**, Jinghua Peng

doi : 10.1016/j.jep.2022.115806

Volume 301, 30 January 2023, 115806

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Commelina benghalensis (Wandering Jew) Linn exhibits abortifacient potentials and hepatotoxicity in pregnant Wistar rats via elevating indicators of oxidative stress and activating proinflammatory cytokines

Adriel Ekozin a,c,*, Chioma N. Adeyemi b, Chiagoziem A. Otuechere

doi : 10.1016/j.jep.2022.115803

Volume 301, 30 January 2023, 115803

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Effective materials and mechanisms study of Tibetan herbal medicine Lagotis integra W. W. Smith treating DSS-induced ulcerative colitis based on network pharmacology, molecular docking and experimental validation

Xinhong Wang a, Chi Zhang a, Lin Liu a, Yuanhan Zhong a, Yujie Wang a, Fangyuan Liu a, Jixiao Zhu a, Zejing Mu a, Shouwen Zhang a, Xiaomin Wang b, Guoyue Zhong a, Jian Liang a,*, Jinxiang Zeng

doi : 10.1016/j.jep.2022.115800

Volume 301, 30 January 2023, 115800

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Overlooked switch from transient sedation to sustained excitement in the Biphasic effects of Ephedra Herb extract administered orally to mice

Xuedan Huang a,b, Sumiko Hyuga b,*, Yoshiaki Amakura c, Masashi Hyuga d, Nahoko Uchiyama d, Takashi Hakamatsuka e, Yukihiro Goda d, Hiroshi Odaguchi b, Toshihiko Hanawa b, Yoshinori Kobayashi

doi : 10.1016/j.jep.2022.115827

Volume 301, 30 January 2023, 115827

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Fufang-zhenzhu-tiaozhi formula protects islet against injury and promotes β cell regeneration in diabetic mice

Xu Chen a,b,c,d,e,1, Jianying Yin a,b,c,d,e,1, Qin Zhong a,b,c,d,e,1, Ke Wang a,b,c, d,e,1, Xiaoyu Zhang a,b,c,d,e, Mingjie Liang a,b,c,d,e, Quanyou Lin a,b,c,d,e, Hong Wang a,b,c, d,e, Weixuan Wang a,b,c,d,e, Lexun Wang a,b,c,d,e, Xuguang Hu a,b,c,d,e, Weijian Bei a,b,c,d, e,*, Jiao Guo

doi : 10.1016/j.jep.2022.115791

Volume 301, 30 January 2023, 115791

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In vitro, in vivo and in silico evaluation of analgesic, anti-inflammatory, and anti-pyretic activity of salicylate rich fraction from Gaultheria trichophylla Royle (Ericaceae)

Fiaz Alam a,*, Muhammad Hanif a, Asad ur Rahman a, Sayyad Ali a, Saeed Jan b

doi : 10.1016/j.jep.2022.115828

Volume 301, 30 January 2023, 115828

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Crosstalk between autophagy and the Keap1-Nrf2-ARE pathway regulates realgar-induced neurotoxicity

Weiwei Zhang a,b, Xu Geng a, Qing Dong a, Xiuhan Li a, Ping Ye a, Mengyuan Lin a, Bin Xu a,**, Hong Jiang

doi : 10.1016/j.jep.2022.115776

Volume 301, 30 January 2023, 115776

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Secondary metabolite contents and safety assessment study of the aqueous extract from the Algerian Echium trygorrhizum Pomel roots

Allaoua Nouri a,b,*, Lakhdar Gasmi b, Amina Safsaf c, Daoud Harzallah d, Seddik Khennouf b, Saliha Dahamna

doi : 10.1016/j.jep.2022.115771

Volume 301, 30 January 2023, 115771

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Exploring the active compounds and potential mechanism of the anti-nonalcoholic fatty liver disease activity of the fraction from Schisandra chinensis fruit extract based on multi-technology integrated network pharmacology

Bin Li a,1, Qi Xiao a,1, Jianuo Zhang a, Yumeng Wang b, Jiushi Liu a, Bengang Zhang a, Haitao Liu

doi : 10.1016/j.jep.2022.115769

Volume 301, 30 January 2023, 115769

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Huaier granule prolongs overall survival after curative resection of hepatocarcinoma carcinoma: A propensity score analysis

Shaoju Luo a,b, Hao Hu

doi : 10.1016/j.jep.2022.115774

Volume 301, 30 January 2023, 115774

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Ethnobotanical study of medicinal plants used by the Kenyah community of Borneo

Keeren Sundara Rajoo a,e,*, Philip Lepun a, Ribka Alan b, Daljit Singh Karam c, Arifin Abdu d, Zamri Rosli a, Norul Izani a, Geoffery James Gerusu

doi : 10.1016/j.jep.2022.115780

Volume 301, 30 January 2023, 115780

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Five centuries of Cirsium ehrenbergii Sch. Bip. (Asteraceae) in Mexico, from Huitzquilitl to Cardo Santo: History, ethnomedicine, pharmacology and chemistry

Silvia Laura Guzm´an-Guti´errez a, Ricardo Reyes-Chilpa b,*, Laura Rigel Gonz´alez-Diego b, Mayra Silva-Miranda a, Alfredo L´opez-Caamal b, Karla Paola Garc?a-Cruz b, Mar?a Sof?a Jim´enez-Mendoza b, Amira Arciniegas b, Clara Espitia c

doi : 10.1016/j.jep.2022.115778

Volume 301, 30 January 2023, 115778

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Antiplasmodial and antimalarial evaluation of a Nigerian hepta-herbal Agbo-iba decoction: Identification of magic bullets and possible facilitators of drug action

Nekpen Erhunse a,b, Ehimwenma Sheena Omoregie b, Dinkar Sahal

doi : 10.1016/j.jep.2022.115807

Volume 301, 30 January 2023, 115807

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Qingre Huoxue Decoction regulates macrophage polarisation to attenuate atherosclerosis through the inhibition of NF-κB signalling-mediated inflammation

Zheng Jin a, Yuan Luo b, Huanyi Zhao c, Jiayan Cui a, Weifeng He b, Junlong Li c, Jianbin Pi d, Lijin Qing c,*, Wei Wu

doi : 10.1016/j.jep.2022.115787

Volume 301, 30 January 2023, 115787

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Structure characterization and anti-fatigue activity of an acidic polysaccharide from Panax ginseng C. A. Meyer

Yang Yu a, Jianing Nie a, Bin Zhao a, Jialiang Tan a, Chongning Lv a,b,**, Jincai Lu

doi : 10.1016/j.jep.2022.115831

Volume 301, 30 January 2023, 115831

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Er-Xian decoction attenuates ovariectomy-induced osteoporosis by modulating fatty acid metabolism and IGF1/PI3K/AKT signaling pathway

Yujie Ma 1, Jing Hu 1, Changheng Song , Pei Li , Yin Cheng , Yuhan Wang , Haixia Liu *, Yanjing Chen **, Zhiguo Zhang

doi : 10.1016/j.jep.2022.115835

Volume 301, 30 January 2023, 115835

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Carob extract induces spermatogenesis in an infertile mouse model via upregulation of Prm1, Plzf, Bcl-6b, Dazl, Ngn3, Stra8, and Smc1b

Zeynab Ghorbaninejad a,b,c, Atiyeh Eghbali a,b,c, Mahsa Ghorbaninejad a,d, Mahdi Ayyari e, Jerzy Zuchowski f, Mariusz Kowalczyk f, Hossein Baharvand a,b, Abdolhossein Shahverdi c, Poopak Eftekhari-Yazdi c,**, Fereshteh Esfandiari

doi : 10.1016/j.jep.2022.115760

Volume 301, 30 January 2023, 115760

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Gancao Fuzi decoction regulates the Th17/Treg cell imbalance in rheumatoid arthritis by targeting Foxp3 via miR-34a

Xiaoshan Zhao a,1, Yankui Yi a,1, Cuiping Jiang a,1, Xintao Huang a, Xiaomin Wen a, Huajun Liao a, Yongyan Zhu a, Yanyan Liu a,***, Nan Li b,**, Dongmei Pan

doi : 10.1016/j.jep.2022.115837

Volume 301, 30 January 2023, 115837

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Xuanfei Baidu Formula attenuates LPS-induced acute lung injury by inhibiting the NF-κB signaling pathway

Yanru Zhu a,b, Lifei Luo a,b, Meng Zhang a,b, Xinbo Song a,b, Ping Wang b, Han Zhang a, Jingze Zhang b, Dailin Liu a,b,*

doi : 10.1016/j.jep.2022.115833

Volume 301, 30 January 2023, 115833

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Qi Jing Mingmu decoction inhibits the p38 signaling pathway in conjunctivochalasis fibroblasts by down-regulation of Th17 cell differentiation

Kai Ma a,1, Jiang Liu a,1, Yongyi Sha a,1, Wei Zhang a, Zhenhua Ni b, Xueqing Kong a, Minhong Xiang

doi : 10.1016/j.jep.2022.115812

Volume 301, 30 January 2023, 115812

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Screening of medicinal plants for possible herb-drug interactions through modulating nuclear receptors, drug-metabolizing enzymes and transporters

Islam Husain a, Olivia R. Dale a, Katherine Martin a, Bill J. Gurley a, Sebastian J. Adams a, Bharathi Avula a, Amar G. Chittiboyina a, Ikhlas A. Khan a,b, Shabana I. Khan

doi : 10.1016/j.jep.2022.115822

Volume 301, 30 January 2023, 115822

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Wutou decoction attenuates the synovial inflammation of collagen-induced arthritis rats via regulating macrophage M1/M2 type polarization

Weiji Lin a, Pan Shen a, Ying Huang b, Liang Han a, Xin Ba a, Yao Huang b, Jiahui Yan a, Tingting Li a, Lijun Xu a, Kai Qin b, Zhe Chen b, Shenghao Tu

doi : 10.1016/j.jep.2022.115802

Volume 301, 30 January 2023, 115802

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Network and experimental pharmacology on mechanism of Si-Wu-tang improving ovarian function in a mouse model of premature ovarian failure induced by cyclophosphamide

Xia Liu a,b, Yufan Song a, Fanru Zhou a, Chu Zhang a, Fan Li a, Runan Hu a, Wenwen Ma a, Kunkun Song a, Zhouping Tang b,**, Mingmin Zhang

doi : 10.1016/j.jep.2022.115842

Volume 301, 30 January 2023, 115842

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Geographical variation in the chemical composition, anti-inflammatory activity of the essential oil, micromorphology and histochemistry of Schinus terebinthifolia Raddi

Janaine Alberto Marangoni a, Jannaina Velasques da Costa Pinto b, Candida Aparecida Leite Kassuya c, Pedro Cruz de Oliveira Junior a, Sidney Mariano dos Santos c, Claudia Andrea Lima Cardoso d, Rosilda Mara Mussury Franco Silva a, Marcia Esp?ndola da Silva a, Camila Dias Machado e, Jane Manfron e, Anelise Samara Nazari Formagio

doi : 10.1016/j.jep.2022.115786

Volume 301, 30 January 2023, 115786

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Biejiajian pill inhibits progression of hepatocellular carcinoma by downregulating PDGFRβ signaling in cancer-associated fibroblasts

Weicong Chen a,b,1, Xuemei Yang b,1, Jialing Sun c, Yuyao Chen b, Wenting Zhao b, Chunyu He b, Haiyan An b, Jie Pang b, Wei Xu b, Bin Wen d,***, Haitao Sun a,b,**, Songqi He

doi : 10.1016/j.jep.2022.115825

Volume 301, 30 January 2023, 115825

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Protective effect of Xingnaojing injection on ferroptosis after cerebral ischemia injury in MCAO rats and SH-SY5Y cells

Haoqi Liu a,1, Na An a,1, Liqin Wang a,b,1, Yuanyuan Li a, Ke Song a, Yikun Sun a,*, Yonghong Gao

doi : 10.1016/j.jep.2022.115836

Volume 301, 30 January 2023, 115836

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Xiehuo Xiaoying decoction inhibits Tfh cell expansion and promotes Tfr cell amplification to ameliorate Graves’ disease

Pingping Xiang a,b,1, Yunnan Zhang a,b,1, Xiaoyang Qu a,b,1, Yu Chen a,b, Yijiao Xu a,b, Xingjia Li a,b, Xiao Wei a,b, Xin Hu a,b, Ronglin Zhong a,b, Chao Liu a,b,*, Fenxia Zhu

doi : 10.1016/j.jep.2022.115826

Volume 301, 30 January 2023, 115826

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Citrate and hydroxycinnamate derivatives from Mume Fructus protect LPS-injured intestinal epithelial cells by regulating the FAK/PI3K/AKT signaling pathway

Zhihua Liu , Zhengxu Zhang , Xiaonan Chen , Ping Ma , Ying Peng **, Xiaobo Li

doi : 10.1016/j.jep.2022.115834

Volume 301, 30 January 2023, 115834

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Coriolus versicolor and its bioactive molecule are potential immunomodulators against cancer cell metastasis via inactivation of MAPK pathway

Cindy Lai-Hung Yang a,b,c, Stanley Chi-Chung Chik a,b,c, Allan Sik-Yin Lau b,c, Godfrey Chi-Fung Chan

doi : 10.1016/j.jep.2022.115790

Volume 301, 30 January 2023, 115790

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Potential anti-arthritic and analgesic properties of essential oil and viridiflorol obtained from Allophylus edulis leaves in mice

Nat´alia de Matos Balsalobre a, Elisangela dos Santos a, Sidney Mariano dos Santos b, Arielle Cristina Arena c, Elisabete Castelon Konkiewitz a, Edward Benjamin Ziff d, Anelise Samara Nazari Formagio b, Candida Aparecida Leite Kassuya

doi : 10.1016/j.jep.2022.115785

Volume 301, 30 January 2023, 115785

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Xinfeng capsule inhibits inflammation and oxidative stress in rheumatoid arthritis by up-regulating LINC00638 and activating Nrf2/HO-1 pathway

Yanqiu Sun a,c, Jian Liu a,c,*, Ling Xin b,c, Jianting Wen a,c, Qin Zhou a,c, Xiaolu Chen a,c, Xiang Ding a,c, Xianheng Zhang

doi : 10.1016/j.jep.2022.115839

Volume 301, 30 January 2023, 115839

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Identification and high-throughput quantification of baicalein and its metabolites in plasma and urine

Hao Wang a,b,1, Yantong Sun c,1, Wei Guo a, Jing Wang a, Jingyi Gao a, Wenwen Peng a, Jingkai Gu a,

doi : 10.1016/j.jep.2022.115853

Volume 301, 30 January 2023, 115853

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Tubiechong patching promotes tibia fracture healing in rats by regulating angiogenesis through the VEGF/ERK1/2 signaling pathway

Xue Wei 1, Jing Wang 1, Yu-Ying Deng, Bing-Hao Shao, Ze-Feng Zhang, Hui-Hui Wang , Chun-Mei Wang

doi : 10.1016/j.jep.2022.115851

Volume 301, 30 January 2023, 115851

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Anti-depressant-like effect of fermented Gastrodia elata Bl. by regulating monoamine levels and BDNF/NMDAR pathways in mice

Ming Gao a,b,1, Yi Wu a,b,1, Lishou Yang a,b, Faju Chen a,b, Liangqun Li a,b, Qiji Li a,b, Yu Wang a,b, Lilang Li a,b, Mei Peng a,b, Yanfang Yan a,b, Juan Yang a,b, Xiaosheng Yang

doi : 10.1016/j.jep.2022.115832

Volume 301, 30 January 2023, 115832

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Bioassay guided fractionation, isolation and characterization of hepatotherapeutic 1, 3-di-ortho-galloyl quinic acid from the methanol extract of the leaves of Pterocarpus santalinoides

Thelma E. Ihedioha a,*, Isaac U. Asuzu a, Aruh O. Anaga a, John I. Ihedioha b, Charles O. Nnadi

doi : 10.1016/j.jep.2022.115864

Volume 301, 30 January 2023, 115864

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Morus alba L. root decreases melanin synthesis via sphingosine-1-phosphate signaling in B16F10 cells

Yulong Zheng , Eun-Hye Lee , So-Yeon Lee , Yeji Lee , Kyong-Oh Shin , Kyungho Park , Il- Jun Kang

doi : 10.1016/j.jep.2022.115848

Volume 301, 30 January 2023, 115848

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Qing-Xin-Jie-Yu Granule inhibits ferroptosis and stabilizes atherosclerotic plaques by regulating the GPX4/xCT signaling pathway

Jie Zhang a,b,1, Xinyi Wang a,c,1, Baoyi Guan a,c, Xue Wang d, Xiaojing An e, Tong Wang a,b, Xuanye Chen a,b, Lin Zhao a,b, Jundi Jia a,b, Luxia Song a,b, Dan Ma a,c, Qiuyi Li a,c, He Zhang a, Jianqing Ju a,**, Hao Xu

doi : 10.1016/j.jep.2022.115852

Volume 301, 30 January 2023, 115852

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Guggulsterone from Commiphora mukul potentiates anti-glioblastoma efficacy of temozolomide in vitro and in vivo via down-regulating EGFR/PI3K/Akt signaling and NF-κB activation

Hong-Bin Xu a,1,*, Xian-Zhen Chen b,1, Zhou-Lun Yu c, Fei Xue b

doi : 10.1016/j.jep.2022.115855

Volume 301, 30 January 2023, 115855

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Hedychium flavum flower essential oil: Chemical composition, anti-inflammatory activities and related mechanisms in vitro and in vivo

Minyi Tian a,b,*, Dan Xie a, Yao Yang a, Yufeng Tian a, Xiaoyan Jia a, Qinqin Wang a, Guodong Deng a, Ying Zhou

doi : 10.1016/j.jep.2022.115846

Volume 301, 30 January 2023, 115846

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Antifungal Annona muricata L. (soursop) extract targets the cell envelope of multi-drug resistant Candida albicans

Lara M. Campos a, Ari S.O. Lemos a, Irley O.M. Diniz a, Lucas A. Carvalho a, Thiago P. Silva b, Paula R.B. Dib c, Eugˆenio D. Hottz c, Luciana M. Chedier d, Rossana C.N. Melo b, Rodrigo L. Fabri

doi : 10.1016/j.jep.2022.115856

Volume 301, 30 January 2023, 115856

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Rhamnogalacturonan-I enriched pectin from steamed ginseng ameliorates lipid metabolism in type 2 diabetic rats via gut microbiota and AMPK pathway

Ting Ren a, Furao Liu a, Dongxue Wang a, Bo Li b, Peng Jiang c, Junming Li a, Hui Li a, Changbao Chen a, Wei Wu a, Lili Jiao

doi : 10.1016/j.jep.2022.115862

Volume 301, 30 January 2023, 115862

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Acute oral toxicity in BALB/c mice of Tridax procumbens and Allium sativum extracts and (3S)-16,17-didehydrofalcarinol

Janelly Burgos-Pino a, Brandon Gual-Orozco b, Marina Vera-Ku b, Elsy Nalleli Lor?a-Cervera c, Leonardo Guillermo-Cordero d, Pedro Pablo Mart?nez-Vega e, Luis W. Torres-Tapia f, Karla Castro-Valencia f, Sergio R. Peraza-S´anchez f,*, Rubi Gamboa-Le´on

doi : 10.1016/j.jep.2022.115840

Volume 301, 30 January 2023, 115840

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Zhachong Shisanwei Pill resists ischemic stroke by lysosome pathway based on proteomics and bioinformatics

Qi Song a,1, Lei Bi a,1, Jiakang Jiao a,1, Jinfeng Shang a,1, Qiannan Li a, Lizha Shabuerjiang a, Meirong Bai b,**, Xin Liu

doi : 10.1016/j.jep.2022.115766

Volume 301, 30 January 2023, 115766

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Systematic elucidation of the bioactive alkaloids and potential mechanism from Sophora flavescens for the treatment of eczema via network pharmacology

Yan Lin a,b,c,d,1, Xing-Jun Chen a,b,c,d,1, Lei He a,b,c,d, Xue-Long Yan a,b,c,d, Qi-Rui Li a,b,c,d , Xu Zhang a,b,c,d, Ming-Hui He a,b,c,d, Shuai Chang a,b,c,d, Bo Tu a,b,c,d,**, Qing-De Long a,b,c,d, *, Zhu Zeng

doi : 10.1016/j.jep.2022.115799

Volume 301, 30 January 2023, 115799

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Integrating network pharmacology and pharmacological evaluation to explore the protective mechanism of Ershiwuwei Zhenzhu pill in ischemic stroke

Cunping Wang a, Qiulin Luo a, Hanyun Que a, Xiaomin Luo a, Boyu Zhang a, Yi Ding a, Rui Tan b, Jian Gu a,**, Puyang Gong

doi : 10.1016/j.jep.2022.115847

Volume 301, 30 January 2023, 115847

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Qi Gong Wan ameliorates adipocyte hypertrophy and inflammation in adipose tissue in a PCOS mouse model through the Nrf2/HO-1/Cyp1b1 pathway: Integrating network pharmacology and experimental validation in vivo

Ruqun Zheng a,1, Haoran Shen b,1, Jie Li a,1, Jiansen Zhao c, Lingjing Lu d,a, Mianhao Hu e, Zixin Lin f, Hongxia Ma a, Huiyan Tan g, Min Hu a, Juan Li

doi : 10.1016/j.jep.2022.115824

Volume 301, 30 January 2023, 115824

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A review on the plant resources of important medicinal licorice

Binbin Yan a,b,c, Junling Hou d, Wenbin Li d, Lin Luo d, Min Ye e, Zhongzhen Zhao d,f,*, Wenquan Wang

doi : 10.1016/j.jep.2022.115823

Volume 301, 30 January 2023, 115823

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Corrigendum to “Diterpene glycosides from Holothuria scabra exert the α-synuclein degradation and neuroprotection from α-synuclein-mediated neurodegeneration in C. elegans model” [J. Ethnopharmacol. 279 (2021) 114347]

Pawanrat Chalorak a, Nilubon Sornkaew b, Preeyanuch Manohong b, Nakorn Niamnont b, Nawapaht Malaiwong a, Tanapol Limboonreung c, Prasert Sobhon a, Michael Aschner d, Krai Meemon

doi : 10.1016/j.jep.2022.115844

Volume 301, 30 January 2023, 115844

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