JAMA - Journal of the American Medical Association




One-year access to more than 500 world journals available in the system
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Effect of Low-Intensity vs High-Intensity Home-Based Walking Exercise on Walk Distance in Patients With Peripheral Artery DiseaseThe LITE Randomized Clinical Trial

Mary M. McDermott, MD; Bonnie Spring, PhD; Lu Tian, ScD; et al.

doi : 10.1001/jama.2021.2536

JAMA. 2021;325(13):1266-1276.

This randomized trial compares the effects of comfortable low-intensity home-based walking exercise vs high-intensity exercise sufficient to elicit ischemic symptoms vs nonexercise control on 6-minute walk distance among patients with peripheral arterial disease (PAD).

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Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon CancerThe CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial

Jeffrey A. Meyerhardt, MD, MPH; Qian Shi, PhD; Charles S. Fuchs, MD, MPH; et al.

doi : 10.1001/jama.2021.2454

JAMA. 2021;325(13):1277-1286.

This randomized trial compares the effect of adding celecoxib to standard adjuvant chemotherapy in improving disease-free survival among patients treated for stage III colon cancer.

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Antimicrobial Use in a Cohort of US Nursing Homes, 2017

Nicola D. Thompson, MS, PhD; Nimalie D. Stone, MD; Cedric J. Brown, MS; et al.

doi : 10.1001/jama.2021.2900

JAMA. 2021;325(13):1286-1295.

This cross-sectional survey assessed the risks of antimicrobial use among 15?276 nursing home residents across 161 facilities.

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Emergence of a Novel SARS-CoV-2 Variant in Southern California

Wenjuan Zhang, PhD; Brian D. Davis, BSc; Stephanie S. Chen, BSc; et al.

doi : 10.1001/jama.2021.1612

JAMA. 2021;325(13):1324-1326.

This research describes findings of sequencing and phylogenetic analyses of SARS-CoV-2 isolates from symptomatic patients cared for at Cedar-Sinai Medical Center in November-December 2020 during a regional surge in cases and hospitalizations.

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Changes in Shooting Incidence in Philadelphia, Pennsylvania, Between March and November 2020

Jessica H. Beard, MD, MPH; Sara F. Jacoby, PhD, MPH; Zoë Maher, MD; et al.

doi : 10.1001/jama.2021.1534

JAMA. 2021;325(13):1327-1328.

This study uses police department registry data to describe trends in incidence of firearm shootings and deaths in January-November 2020, before and after the closure of nonessential businesses in March, the killing of George Floyd in May, and the partial lifting of containment policies in June.

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Trends in Age at Natural Menopause and Reproductive Life Span Among US Women, 1959-2018

Duke Appiah, PhD, MPH; Chike C. Nwabuo, MD, MPH; Imo A. Ebong, MD, MS; et al.

doi : 10.1001/jama.2021.0278

JAMA. 2021;325(13):1328-1330.

This national survey study uses the National Health and Nutrition Examination Survey (NHANES) to describe trends in age at natural menopause, age at menarche, and reproductive life span, and variables associated with shorter and longer spans, among US women between 1959-1962 and 2015-2018.

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Reinventing the Center for Medicare and Medicaid Innovation

Donald M. Berwick, MD; Rick Gilfillan, MD

doi : 10.1001/jama.2021.3203

JAMA. 2021;325(13):1247-1248.

This Viewpoint makes 6 recommendations for how the Center for Medicare and Medicaid Innovation, as it enters its second decade, can better fulfill its mission of testing health care payment and service delivery models and scale them up to a national level to reduce health care expenditures and improve quality and safety.

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The Potential Future of the COVID-19 PandemicWill SARS-CoV-2 Become a Recurrent Seasonal Infection?

Christopher J. L. Murray, MD; Peter Piot, MD

doi : 10.1001/jama.2021.2828

JAMA. 2021;325(13):1249-1250.

This Viewpoint discusses the prospect that COVID-19 could become a recurrent seasonal disease like influenza and proposes strategies to mitigate the consequences for communities and health systems, including changes in surveillance, medical and public health response, and socioeconomic programs.

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Approaches for Optimal Use of Different COVID-19 VaccinesIssues of Viral Variants and Vaccine Efficacy

John P. Moore, PhD

doi : 10.1001/jama.2021.3465

JAMA. 2021;325(13):1251-1252.

This Viewpoint proposes ways to maximize vaccine efficacy and allocation given the rise of coronavirus variants and authorization of a Johnson & Johnson vaccine, including reserving the latter for younger healthier populations, boosting it with a single-dose messenger RNA (mRNA) vaccination, and single mRNA immunization of people with prior documented SARS-CoV-2 infection.

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The Future of Health Policy in a Partisan United StatesInsights From Public Opinion Polls

Robert J. Blendon, ScD; John M. Benson, MA; Eric C. Schneider, MD

doi : 10.1001/jama.2021.1147

JAMA. 2021;325(13):1253-1254.

This Viewpoint summarizes views measured in national opinion polls about COVID-19 response, national health insurance reform, reforming the US health care system in general, and race and race disparities in health, with a focus on differences between Democrat and Republican respondents and implications of those differences for enacting meaningful legislation.

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Sitting in the River

Jessi Humphreys, MD

doi : 10.1001/jama.2021.3857

JAMA. 2021;325(13):1255-1256.

In this narrative medicine essay, a palliative care physician finds the space between professional and patient distance thinning as the COVID pandemic drags on and wonders whether abiding with them is the lesson.

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Celecoxib for Stage III Colon Cancer

David J. Kerr, MD, DSc; Sarah Chamberlain, BMedSci, MBChB; Rachel S. Kerr, MBChB, PhD

doi : 10.1001/jama.2021.2651

JAMA. 2021;325(13):1257-1258.

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Opportunities to Improve Antimicrobial Use in US Nursing Homes

Christopher J. Crnich, MD, PhD; Preeti Malani, MD, MSJ

doi : 10.1001/jama.2021.3258

JAMA. 2021;325(13):1259-1260.

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SARS-CoV-2 Viral Variants—Tackling a Moving Target

John R. Mascola, MD; Barney S. Graham, MD, PhD; Anthony S. Fauci, MD

doi : 10.1001/jama.2021.2088

JAMA. 2021;325(13):1261-1262.

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To JAMA Authors, Reviewers, and Especially Physician Readers—A Profound Thank You

Phil B. Fontanarosa, MD, MBA; Howard Bauchner, MD; Robert Golub, MD

doi : 10.1001/jama.2021.3860

JAMA. 2021;325(13):1263-1265.

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Filtering Facepiece Respirator (N95 Respirator) ReprocessingA Systematic Review

Max A. Schumm, MD; Joseph E. Hadaya, MD; Nisha Mody, MLIS, MA, CCC-SLP; et al.

doi : 10.1001/jama.2021.2531

JAMA. 2021;325(13):1296-1317.

In the context of widespread reuse and reprocessing of N95 respirators due to shortages caused by the COVID-19 pandemic, this systematic review summarizes evidence on effectiveness and feasibility of 5 decontaminating processes: UV irradiation, vaporized hydrogen peroxide, moist-heat incubation, microwave-generated steam, and ethylene oxide.

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SARS-CoV-2 Vaccines

C. Buddy Creech, MD, MPH; Shannon C. Walker, MD; Robert J. Samuels, MBChB

doi : 10.1001/jama.2021.3199

JAMA. 2021;325(13):1318-1320.

This JAMA Insights clinical review explains different approaches to SARS-CoV-2 vaccine development, including inactivated and protein subunit, viral vector, and mRNA immunization strategies, and summarizes safety and efficacy data for global products authorized for use or in later-stage clinical trials.

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Drugs for Atopic Dermatitis

doi : 10.1001/jama.2020.11192

JAMA. 2021;325(13):1321-1322.

This Medical Letter provides a Table summarizing key information about topical corticosteroids available for atopic dermatitis published as part of a comprehensive review on the topic.

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COVID-19 Vaccines vs Variants—Determining How Much Immunity Is Enough

Rita Rubin, MA

doi : 10.1001/jama.2021.3370

JAMA. 2021;325(13):1241-1243.

This Medical News feature examines what is known about the efficacy of COVID-19 vaccines against SARS-CoV-2 variants.

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Experts Discuss COVID-19—Vaccine Questions, School Openings, and More

doi : 10.1001/jama.2021.4121

JAMA. 2021;325(13):1244-1245.

This Medical News article is a roundup of insights from recent livestream interviews with leading experts.

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A First in Surgical Devices for Transvaginal Hysterectomy

Rebecca Voelker, MSJ

doi : 10.1001/jama.2021.4592

JAMA. 2021;325(13):1246.

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3D-Printed Implant Is Approved to Replace Ankle Joint Bone

Rebecca Voelker, MSJ

doi : 10.1001/jama.2021.4029

JAMA. 2021;325(13):1246.

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Thermal Imaging Systems May Pose Public Health Risks

Rebecca Voelker, MSJ

doi : 10.1001/jama.2021.4594

JAMA. 2021;325(13):1246.

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Passing Out at the Hospital

Don Barkin, MA

doi : 10.1001/jama.2021.1001

JAMA. 2021;325(13):1336.

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The Medical Profession and the Public

doi : 10.1001/jama.2020.17870

JAMA. 2021;325(13):1337.

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JAMA Peer Reviewers in 2020

doi : 10.1001/jama.2021.0638

JAMA. 2021;325(13):1338-1350.

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Giardiasis

Angel N. Desai, MD, MPH

doi : 10.1001/jama.2020.10289

JAMA. 2021;325(13):1356.

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Whistleblowing and Misconduct at Large Pharmaceutical Firms

Takanao Hashimoto, PhD; Akihiko Ozaki, MD, PhD; Tetsuya Tanimoto, MD

doi : 10.1001/jama.2021.0573

JAMA. 2021;325(13):1331.

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Whistleblowing and Misconduct at Large Pharmaceutical Firms—Reply

Denis G. Arnold, PhD; Tammy Beck, PhD; Oscar Jerome Stewart, PhD

doi : 10.1001/jama.2021.0576

JAMA. 2021;325(13):1331-1332.

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Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk

Brian Olshansky, MD; Deepak L. Bhatt, MD; Mina K. Chung, MD

doi : 10.1001/jama.2021.0824

JAMA. 2021;325(13):1332-1333.

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Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk

Francine Welty, MD, PhD; Bruce Bistrian, MD, PhD; David Driscoll, PhD

doi : 10.1001/jama.2021.0830

JAMA. 2021;325(13):1333.

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Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk

Yutang Wang, PhD

doi : 10.1001/jama.2021.0821

JAMA. 2021;325(13):1333.

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Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk

Kye-Yeung Park, MD, PhD; Hoon-Ki Park, MD, PhD; Hwan-Sik Hwang, MD, PhD

doi : 10.1001/jama.2021.0827

JAMA. 2021;325(13):1334.

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Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk—Reply

Steven E. Nissen, MD; A. Michael Lincoff, MD; Stephen J. Nicholls, MBBS, PhD

doi : 10.1001/jama.2021.0839

JAMA. 2021;325(13):1334-1335.

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Group Name Omitted

doi : 10.1001/jama.2021.2565

JAMA. 2021;325(13):1335.

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Errors in Results

doi : 10.1001/jama.2021.2802

JAMA. 2021;325(13):1335.

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Update of Image Credit and Word Choice

doi : 10.1001/jama.2021.3751

JAMA. 2021;325(13):1335.

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Two Incomplete Author Names

doi : 10.1001/jama.2021.3920

JAMA. 2021;325(13):1335.

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