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Poor communication between ER and mitochondria: a signature of ALS/FTD?
Christopher C.J. Miller, Patricia Gomez-Suaga
doi : 10.18632/aging.205206
Volume 15, Issue 20
Cholinergic centro-cingulate network in Parkinson disease and normal aging
Nicolaas I. Bohnen, Sygrid van der Zee, Roger Albin
doi : 10.18632/aging.205209
Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature
Shweta S. Dipali, Christina D. King, Jacob P. Rose, Joanna E. Burdette, Judith Campisi, Birgit Schilling, Francesca E. Duncan
doi : 10.18632/aging.205190
Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes
MarÃa Marchante, Noelia Ramirez-Martin, Anna Buigues, Jessica Martinez, Nuria Pellicer, Antonio Pellicer, Sonia Herraiz
doi : 10.18632/aging.205086
Tissue immunoexpression of IL-6 and IL-18 in aging men with BPH and MetS and their relationship with lipid parameters and gut microbiota-derived short chain fatty acids
Weronika Ratajczak, Maria Laszczyńska, Aleksandra Rył, Barbara Dołęgowska, Olimpia Sipak, Ewa Stachowska, Marcin Słojewski, Anna Lubkowska
doi : 10.18632/aging.205091
WNT enhancing signals in pancreatic cancer are transmitted by LGR6
Jing Wang, Dominik T. Koch, Felix O. Hofmann, Daniel Härtwig, Iris Beirith, Klaus Peter Janssen, Alexandr V. Bazhin, Hanno Niess, Jens Werner, Bernhard W. Renz, Matthias Ilmer
doi : 10.18632/aging.205101
The Saccharomyces cerevisiae acetyltransferase Gcn5 exerts antagonistic pleiotropic effects on chronological ageing
Kaiqiang Li, Gabriele Mocciaro, Jules L. Griffin, Nianshu Zhang
doi : 10.18632/aging.205109
Alcohol consumption and epigenetic age acceleration across human adulthood
Mengyao Wang, Yi Li, Meng Lai, Drew R. Nannini, Lifang Hou, Roby Joehanes, Tianxiao Huan, Daniel Levy, Jiantao Ma, Chunyu Liu
doi : 10.18632/aging.205153
Chronic kidney disease causes blood-brain barrier breakdown via urea-activated matrix metalloproteinase-2 and insolubility of tau protein
Hisazumi Matsuki, Shintaro Mandai, Hiroki Shiwaku, Takaaki Koide, Naohiro Takahashi, Tomoki Yanagi, Shunsuke Inaba, Saaya Ida, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Eisei Sohara, Hidehiko Takahashi, Shinichi Uchida
doi : 10.18632/aging.205164
BTN2A2, a new biomarker and therapeutic target for glioma
Heping Wang, Shanrui Pu, Haitao Xu, Lihong Yang, Lishi Shao, Xi Chen, Xiaobin Huang, Jun Pu
doi : 10.18632/aging.205039
A comprehensive prognostic and immunological analysis of telomere-related lncRNAs in kidney renal clear cell carcinoma
Ji Chen, Dong Zhang, Xiangbin Ren, Peng Wang
doi : 10.18632/aging.205056
Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis
Shiue-Wei Lai, Yi-Chiao Cheng, Wen-Chien Huang, Vijesh Kumar Yadav, Iat-Hang Fong, Chi-Tai Yeh, Ching-Kuo Yang, Wei-Hwa Lee, Ming-Yao Chen
doi : 10.18632/aging.205064
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma
Haitao Luo, Kai Huang, Mengqi Cheng, Xiaoyan Long, Xingen Zhu, Miaojing Wu
doi : 10.18632/aging.205076
HLA-DPA1 overexpression inhibits cancer progression, reduces resistance to cisplatin, and correlates with increased immune infiltration in lung adenocarcinoma
Ke Shi, Qian-Yun Li, Yun-Qiang Zhang, Huan Huang, Dong-Xiao Ding, Wei-Min Luo, Jun Zhang, Qiang Guo
doi : 10.18632/aging.205082
Identification and validation of a cancer-associated fibroblasts-related scoring system to predict prognosis and immune landscape in hepatocellular carcinoma through integrated analysis of single-cell and bulk RNA-sequencing
Lingling Bao, Xuede Zhang, Wenjuan Wang, Bitao Jiang
doi : 10.18632/aging.205099
Naked cuticle homolog 1 prevents mouse pulmonary arterial hypertension via inhibition of Wnt/β-catenin and oxidative stress
Shanwu Wei, Lu Lin, Wen Jiang, Jie Chen, Gu Gong, Daming Sui
doi : 10.18632/aging.205105
Triptolide inhibits epithelial ovarian tumor growth by blocking the hedgehog/Gli pathway
Lanyan Hu, Mai Gao, Huifu Jiang, Lingling Zhuang, Ying Jiang, Siqi Xie, Hong Zhang, Qian Wang, Qi Chen
doi : 10.18632/aging.205110
The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway
Jing Xu, Peng Chen, Dongzhi Wu, Qiang Zhou, Sijie Chen, Xiang Ding, Hongping Xiong
doi : 10.18632/aging.205118
Machine learning developed a PI3K/Akt pathway-related signature for predicting prognosis and drug sensitivity in ovarian cancer
Xiaofang Han, Liu Yang, Hui Tian, Yuanyuan Ji
doi : 10.18632/aging.205119
Inhibiting microRNA-200a-3p attenuates pyroptosis via targeting the SIRT1/NF-κB/NLRP3 pathway in H2O2-induced HAEC
Jia Liu, Youyou Yan, Dongdong Zheng, Jifeng Zhang, Junnan Wang
doi : 10.18632/aging.205121
Tryptophan metabolism-related gene expression patterns: unveiling prognostic insights and immune landscapes in uveal melanoma
Jing Wang, Tienan Zhao, Bo Li, Wei Wei
doi : 10.18632/aging.205122
Identification of cellular senescence-related signature for predicting prognosis and therapeutic response of acute myeloid leukemia
Fangmin Zhong, Yulin Yang, Fangyi Yao, Jing Liu, Xiajing Yu, Xin-Lu Wang, Bo Huang, Xiao-Zhong Wang
doi : 10.18632/aging.205123
Electroacupuncture pretreatment protects against anesthesia/surgery-induced cognitive decline by activating CREB via the ERK/MAPK pathway in the hippocampal CA1 region in aged rats
Hongjie Huang, Yanan Li, Xupeng Wang, Qi Zhang, Juan Zhao, Qiujun Wang
doi : 10.18632/aging.205124
CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model
Hong Wan, Xiaowei Yang, Guopeng Sang, Zhifan Ruan, Zichen Ling, Mingzhao Zhang, Chang Liu, Xiangyang Hu, Tao Guo, Juntong He, Defeng Liu, Jing Pei
doi : 10.18632/aging.205125
Integrated bulk and scRNA sequence identified anoikis-related diagnostic biomarkers and potential association with immune infiltration in type A aortic dissection
Kexiang Feng, Zhongwei Zhang, Jie Luo, Wenjie Wang, Tianjie Li, Jing Luo, Hongbo Huang
doi : 10.18632/aging.205126
STK4 is a prognostic biomarker correlated with immune infiltrates in clear cell renal cell carcinoma
Zi-Yuan Bai, Lu-Shan Peng, Run-Qi Li, Xianchu Peng, Zhe Yang
doi : 10.18632/aging.205127
Single-cell landscape and spatial transcriptomic analysis reveals macrophage infiltration and glycolytic metabolism in kidney renal clear cell carcinoma
Chen-Yueh Wen, Jui-Hu Hsiao, Yen-Dun Tony Tzeng, Renin Chang, Yi-Ling Tsang, Chen-Hsin Kuo, Chia-Jung Li
doi : 10.18632/aging.205128
Role of NF-κB pathway in kidney renal clear cell carcinoma and its potential therapeutic implications
Jiaao Sun, Feng Chen, Guangzhen Wu
doi : 10.18632/aging.205129
Exosome and lipid metabolism-related genes in pancreatic adenocarcinoma: a prognosis analysis
Jia Wu, Yajun Li, Ghulam Nabi, Xin Huang, Xu Zhang, Yuanzhen Wang, Liya Huang
doi : 10.18632/aging.205130
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer
Yang Liu, Jia-Xin He, Bo Ji, Jin-Feng Wang, Lu Zhang, Zhong-Qi Pang, Jian-She Wang, Bei-Chen Ding, Ming-Hua Ren
doi : 10.18632/aging.205131
Development of an immunogenic cell death prognostic signature for predicting clinical outcome and immune infiltration characterization in stomach adenocarcinoma
Ye Liu, Lijia Zhang, Xue Lei, Xinyu Yin, Songjiang Liu
doi : 10.18632/aging.205132
Molecular characterization of ferroptosis in soft tissue sarcoma constructs a prognostic and immunotherapeutic signature through experimental and bioinformatics analyses
Zhi-Qiang Yang, Liang-Yu Guo, Kang-Wen Xiao, Chong Zhang, Min-Hao Wu, Fei-Fei Yan, Lin Cai
doi : 10.18632/aging.205133
PPIH gene regulation system and its prognostic significance in hepatocellular carcinoma: a comprehensive analysis
Jun Ye, Yilin Pang, Xunjun Yang, Chuan Zhang, Lei Shi, Zhitao Chen, Guijia Huang, Xianhe Wang, Fangyang Lu
doi : 10.18632/aging.205134
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study
Yuanqing Cai, Huijun Sun, Xingyu Song, Jianyu Zhao, Dong Xu, Mozhen Liu
doi : 10.18632/aging.205136
Anti-cancer targets and molecular mechanisms of formononetin in treating osteosarcoma based on network pharmacology
Lizhi Chen, Yue Zhou, Zheng Weng, Shuang Liu, Ting Li, Yanfang Wang, Yang Yang, Hongmei Liu, Wenhua Huang
doi : 10.18632/aging.205139
Single-cell analysis reveals exosome-associated biomarkers for prognostic prediction and immunotherapy in lung adenocarcinoma
Shengrong Lin, Shengjie Zhou, Xin Han, Yang Yang, Hao Zhou, Xuejiao Chang, Yefeng Zhou, Yuqin Ding, Huihui Lin, Qing Hu
doi : 10.18632/aging.205140
Indoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α–FNDC5 axis
Yi-Chou Hou, Min-Tser Liao, Kuo-Wang Tsai, Cai-Mei Zheng, Hui-Wen Chiu, Kuo-Cheng Lu
doi : 10.18632/aging.205141
Icariin improves cognitive impairment by inhibiting ferroptosis of nerve cells
Yang Yang, Yiming Fu, Zhipeng Qin, Hongyan Pei, Liping Zhai, Qiaobing Guan, Shasha Wu, Heping Shen
doi : 10.18632/aging.205144
Comprehensive analysis of transcriptome data and experimental identification show that solute carrier 35 member A2 (SLC35A2) is a prognostic marker of colorectal cancer
Yue Wang, Liang Chen, Jing Chen, Zhenzhen Bai, Liyu Cao
doi : 10.18632/aging.205145
Metabolic and senescence characteristics associated with the immune microenvironment in non-small cell lung cancer: insights from single-cell RNA sequencing
Hongliang Liao, Zihao Wan, Yaqin Liang, Lin Kang, Renping Wan
doi : 10.18632/aging.205146
Immunobiological signatures and the emerging role of SPP1 in predicting tumor heterogeneity, malignancy, and clinical outcomes in stomach adenocarcinoma
Yanan Wu, Lingyu Ren, Yichun Tang, Zhu Zhu, Shifan Liu, Yan Jiang, Siming Zhang, Xiaocan Zhuang, Yuanbiao Chen
doi : 10.18632/aging.205148
BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas
Lun Gao, Zhang Ye, Shu Peng, Pan Lei, Ping Song, Zhiyang Li, Long Zhou, Qiuwei Hua, Li Cheng, Hangyu Wei, Junhui Liu, Qiang Cai
doi : 10.18632/aging.205149
Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway
Huihong Li, Caiyun Zhang, Yangjie Zhou, Yunfei Deng, Xiaoqing Zheng, Xiehua Xue
doi : 10.18632/aging.205151
PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway
Jiacheng Zhong, Chao Yuan, Lin Liu, Yang Du, Yumin Hui, Zhiyuan Chen, Changhui Diao, Rui Yang, Guiyong Liu, Xiuheng Liu
doi : 10.18632/aging.205152
Identification of key circadian rhythm genes in skin aging based on bioinformatics and machine learning
Xiao Xiao, Hao Feng, Yangying Liao, Hua Tang, Lan Li, Ke Li, Feng Hu
doi : 10.18632/aging.205155
Correction for: ASXL1 promotes adrenocortical carcinoma and is associated with chemoresistance to EDP regimen
Liang Wang, Yinfeng Lyu, Yuqing Li, Kunping Li, Hui Wen, Chenchen Feng, Ning Li
doi : 10.18632/aging.205255
Correction for: miR-320 accelerates chronic heart failure with cardiac fibrosis through activation of the IL6/STAT3 axis
Fang Li, Shan-Shan Li, Hui Chen, Jian-Zhi Zhao, Jie Hao, Jin-Ming Liu, Xiu-Guang Zu, Wei Cui
doi : 10.18632/aging.205256
