Diabetes, Obesity and Metabolism




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Diabetes, Obesity and Metabolism

doi : 10.1111/dom.14758

Volume 25, Issue 11

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The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

L?rke S. Gasbjerg MD 1,2 | Mette M. Rosenkilde MD 1 | Juris J. Meier MD 3 | Jens J. Holst MD 1,4 | Filip K. Knop MD

doi : 10.1111/dom.15216

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In praise of pioglitazone: An economically efficacious therapy for type 2 diabetes and other manifestations of the metabolic syndrome

David S. H. Bell MB 1 | Terri Jerkins MD

doi : 10.1111/dom.15222

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Adaptive bolus calculators for people with type 1 diabetes: A systematic review

Rebecca Unsworth MB | Parizad Avari PhD | Aaron M. Lett PhD | Nick Oliver FRCP | Monika Reddy PhD

doi : 10.1111/dom.15204

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Hypoglycaemia induces a sustained pro-inflammatory response in people with type 1 diabetes and healthy controls

Clementine E. M. Verhulst MD 1 | Julia I. P. van Heck MSc 1 | Therese W. Fabricius MD 2 | Rinke Stienstra PhD 1,3 | Steven Teerenstra PhD 4 | Rory J. McCrimmon PhD 5 | Cees J. Tack PhD 1 | Ulrik Pedersen-Bjergaard PhD 2,6 | Bastiaan E. de Galan PhD 1,7,8 | on behalf of the Hypo-RESOLVE consortium

doi : 10.1111/dom.15205

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Relationship between the magnitude of body mass index reductions and remission in patients with type 2 diabetes in real world settings: Analysis of nationwide patient registry in Japan (JDDM74)

Kazuya Fujihara MD 1 | Laymon Khin MD 1 | Koshiro Murai MD 1 | Yurie Yamazaki MD 1 | Kahori Tsuruoka RN 1 | Noriko Yagyuda RN 1 | Katsuya Yamazaki MD 2 | Hiroshi Maegawa MD 3 | Shiro Tanaka PhD 4 | Satoru Kodama MD 1 | Hirohito Sone MD 1 | JDDM Study Group

doi : 10.1111/dom.15206

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Testing for associations between HbA1c levels, polygenic risk and brain health in UK Biobank (N = 39 283)

Sanskar Ranglani 1 | Joey Ward PhD 2 | Naveed Sattar PhD 3 | Rona J. Strawbridge PhD 2,4,5 | Donald M. Lyall PhD

doi : 10.1111/dom.15207

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Changes in the glycaemia risk index and its association with other continuous glucose monitoring metrics after initiation of an automated insulin delivery system in adults with type 1 diabetes

Kagan E. Karakus MD 1,2 | Viral N. Shah MD 1 | David Klonoff MD 3 | Halis K. Akturk MD

doi : 10.1111/dom.15208

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Overall and inter-individual effect of four different drug classes on soluble urokinase plasminogen activator receptor in type 1 and type 2 diabetes

Viktor Rotbain Curovic MD 1 | Morten B. Houlind PhD 2,3 | Marjolein Y. A. M. Kroonen PhD 4 | Niels Jongs PhD 4 | Emilie H. Zobel DMSc 1 | Tine W. Hansen PhD 1 | Juliette Tavenier PhD 2 | Jesper Eugen-Olsen PhD 2 | Gozewijn D. Laverman PhD 5 | Adriaan Kooy PhD 4,6 | Frederik Persson DMSc 1 | Peter Rossing DMSc 1,3 | Hiddo J. L. Heerspink PhD

doi : 10.1111/dom.15209

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Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study

Kathrine J. Vinknes PhD 1 | Thomas Olsen PhD 1 | Hasse Khiabani Zaré PhD 2 | Nasser E. Bastani PhD 1 | Emma Stolt MSc 1 | Anja F. Dahl MSc 1 | Roger D. Cox PhD 3 | Helga Refsum PhD 1,4 | Kjetil Retterst?l PhD 1,5 | Anders ?sberg PhD 6,7 | Amany Elshorbagy PhD

doi : 10.1111/dom.15210

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A model-based approach to predict individual weight loss with semaglutide in people with overweight or obesity

Anders Strathe PhD 1 | Deborah B. Horn DO 2 | Malte Selch Larsen PhD 1 | Domenica Rubino MD 3 | Rasmus S?rrig PhD 1 | Marie Thi Dao Tran MD 1 | Sean Wharton MD 4 | Rune Viig Overgaard PhD

doi : 10.1111/dom.15211

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Fat-to-muscle ratio is associated with insulin resistance and cardiometabolic disorders in adults with type 1 diabetes mellitus

Fansu Huang MD 1,2 | Xiaolin Ji MD 2 | Zhen Wang PhD 2 | Yixuan Yin MD 2 | Li Fan MD 2 | Juan Li MD 2 | Zhiguang Zhou PhD 2 | Xia Li PhD

doi : 10.1111/dom.15212

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Adipose tissue-derived FABP4 mediates glucagon-stimulated hepatic glucose production in gestational diabetes

Idit Ron PhD 1 | Ragad Mdah MSc 1,2 | Roni Zemet MD 2,3,4 | Rakefet Yoeli Ulman MD 3 | Moran Rathaus PhD 1 | Benny Brandt MD 3,5 | Shali Mazaki-Tovi MD 2,3 | Rina Hemi PhD 1 | Ehud Barhod PhD 1 | Amir Tirosh PhD

doi : 10.1111/dom.15214

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Healthy lifestyle and all-cause and cause-specific dementia in individuals with type 2 diabetes and the roles of diabetes duration and insulin use in UK Biobank cohort

Chunmiao Zhou BS 1 | Caiyun Dong BS 1 | Qi Wang MPH 2,3 | Chunying Fu BM 1 | Ziwei Xie BS 1 | Wenting Hao MD 2,3 | Huizi Sun BS 1 | Dongshan Zhu PhD

doi : 10.1111/dom.15215

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Twelve-month results of the ADAPT randomized controlled trial: Reproducibility and sustainability of advanced hybrid closed-loop therapy outcomes versus conventional therapy in adults with type 1 diabetes

Shannon N. Edd PhD 1 | Javier Casta?eda MS 2 | Pratik Choudhary MBBS 3,4 | Ralf Kolassa MD 5 | Winfried Keuthage MD 6 | Jens Kroeger MD 7 | Charles Thivolet MD 8 | Mark Evans MD 9 | Roseline Ré MS 1 | Jessica Cellot MS 1 | Simona de Portu PharmD 1 | Linda Vorrink MS 1 | John Shin PhD 10 | Tim van den Heuvel PhD 2 | Ohad Cohen MD 1 | on behalf of the ADAPT study Group

doi : 10.1111/dom.15217

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Effects of once-weekly glucagon-like peptide-1 receptor agonists on type 2 diabetes mellitus complicated with coronary artery disease: Potential role of the renin-angiotensin system

Mengfan Kan MSc 1 | Hui Fu MD 2 | Yunsheng Xu MD 3 | Zhaodi Yue MSc 4 | Bingyu Du MSc 4 | Qiang Chen MSc 4 | Xueyin Wang MSc 5 | Shaohong Yu MD 6,7 | Zhongwen Zhang MD

doi : 10.1111/dom.15219

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The associations of sodium-glucose cotransporter-2 inhibitors versus dipeptidyl peptidase-4 inhibitors as add-on to metformin with fracture risk in patients with type 2 diabetes mellitus

Veerle van Hulten MSc 1,2,3,4 | Johanna H. M. Driessen PhD 1,2,3,4 | Jakob K. Starup-Linde PhD 5 | Zheer K. Al-Mashhadi MD 5,6,7 | Rikke Viggers MD 8,9 | Olaf H. Klungel PhD 4 | Patrick C. Souverein PhD 4 | Peter Vestergaard MD 8,10 | Coen D. A. Stehouwer MD 11 | Joop P. van den Bergh MD

doi : 10.1111/dom.15220

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Safety of sodium-glucose co-transporter-2 inhibitors on amputation across categories of baseline cardiovascular disease and diuretics use in patients with type 2 diabetes

Sohee Park PhD 1,2 | Han Eol Jeong PhD 1,3 | Sungho Bea PharmD 1 | Oriana H. Y. Yu MD 4,5 | Young Min Cho PhD 6,7,8,9 | Seng Chan You PhD 10 | Kenneth K. C. Man PhD 2,11,12 | Ju-Young Shin PhD

doi : 10.1111/dom.15221

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Associations of lipoprotein subclasses with risk of all-cause and cardiovascular disease mortality in individuals with type 2 diabetes: A prospective cohort study

Rui Li MS 1 | Jun-Xiang Chen MBBS 2 | Qi Lu MBBS 1 | Ting-Ting Geng PhD 1 | Peng-Fei Xia MBBS 2 | Yi Wang MBBS 2 | Liang-Kai Chen PhD 1 | Zhi-Lei Shan PhD 1 | An Pan PhD 2 | Gang Liu PhD

doi : 10.1111/dom.15224

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Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice

Alba Sanz-Gonz?lez MSc 1 | Irene C ozar-Castellano PhD 1,2 | Christophe Broca PhD 3 | Julia Sabatier PhD 3 | Gerardo A. Acosta PhD 4,5,6 | Miriam Royo PhD 4,5 | Carla Hern?ndo-Mu?oz MSc 7 | Tom?s Torroba PhD 7 | Germ?n Perdomo PhD 1 | Beatriz Merino PhD

doi : 10.1111/dom.15225

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Comparative efficacy of digitally assisted interventions for glycated haemoglobin levels among patients with type 2 diabetes: A systematic review and component network Meta-Analysis

Debby Syahru Romadlon PhD 1,2 | Yu-Kang Tu PhD 3,4 | Yang-Ching Chen PhD 5,6 | Faizul Hasan PhD 1,2 | Hsiao-Yean Chiu PhD

doi : 10.1111/dom.15227

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Initial antibiotic therapy for postoperative moderate or severe diabetic foot infections: Broad versus narrow spectrum, empirical versus targeted

Arend J. Nieuwland MD 1 | Felix W. A. Waibel MD 1 | Andreas Flury MD 1 | Marcus Lisy MD 1 | Martin C. Berli MD 1 | Benjamin A. Lipsky MD 2 | _Ilker Uçkay MD 1,3,4 | Madlaina Sch?ni MD

doi : 10.1111/dom.15228

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Labisia pumila standardized extract (SKF7®) reduces percentage of waist circumference and waist-to-height ratio in individuals with obesity

Yogarabindranath Swarna Nantha PhD 1 | Shalini Vijayasingham MRCP 2 | Noor Lita Adam MMed 3 | Paranthaman Vengadasalam MMed 4 | Mastura Ismail MMed 5 | Norsiah Ali MMed 6 | Li Cheng Chang MMed 7 | Lena Yeap Lay Ling MSc 8 | Thiam-Tsui Tee PhD 9 | Yew-Hoong Cheah PhD

doi : 10.1111/dom.15229

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Glucose-lowering drug use in migrants and native Danes with type 2 diabetes: Disparities in combination therapy and drug types

Anders Aasted Isaksen MD 1,2 | Annelli Sandb?k PhD 1,2,3 | Mette Vinther Skriver PhD 1 | Lasse Bjerg PhD

doi : 10.1111/dom.15230

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A J-shaped relationship between ketones and the risk of diabetic kidney disease in patients with type 2 diabetes: New insights from a cross-sectional study

Ying Liu MD 1,2 | Jingyu Wang MD 1 | Fang Xu PhD 1,3 | Shuang Zhang MD 1,4 | Shanshan Cui MD 1,2 | Yongmei Li PhD 1 | Xiaoyu Wang MD 1,2 | Hui Zheng PhD 1,5 | Junfeng Li MD 2 | Yan Kong MD 1 | Juhong Yang PhD 1 | Xia Jiang BD 2 | Baocheng Chang PhD

doi : 10.1111/dom.15231

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Estimated lifetime benefit of novel pharmacological therapies in patients with type 2 diabetes and chronic kidney disease: A joint analysis of randomized controlled clinical trials

Hiddo J. L. Heerspink PhD 1,2 | Priya Vart PhD 1 | Niels Jongs PhD 1 | Brendon L. Neuen MD 2 | George Bakris MD 3 | Brian Claggett PhD 4 | Muthiah Vaduganathan MD 4 | Finnian McCausland MD 4 | Kieran F. Docherty MBChB 5 | Pardeep S. Jhund PhD 5 | Scott D. Solomon MD 4 | Vlado Perkovic PhD 2,6 | John J. V. McMurray MD

doi : 10.1111/dom.15232

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Remnant cholesterol, but not low-density lipoprotein cholesterol, is associated with intra-pancreatic fat deposition

Loren Skudder-Hill MBBS 1 | Ivana R. Sequeira-Bisson PhD 2,3 | Juyeon Ko PhD 1 | Jaelim Cho PhD 4 | Sally D. Poppitt PhD 1,2,3 | Maxim S. Petrov PhD

doi : 10.1111/dom.15233

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Diabetes remission and relapse following an intensive metabolic intervention combining insulin glargine/lixisenatide, metformin and lifestyle approaches: Results of a randomised controlled trial

Natalia McInnes MD 1,2,3 | Stephanie Hall BHA 2 | Heather A. Lochnan MD 4 | Stewart B. Harris MD 5 | Zubin Punthakee MD 1,2 | Ronald J. Sigal MD 6 | Irene Hramiak MD 5 | Mohammed Azharuddin MD 7 | Joanne F. Liutkus MD 8 | Jean-François Yale MD 9 | Farah Sultan MSc 3 | Ada Smith BScN 1 | Rose E. Otto BASc 1 | Diana Sherifali PhD 10 | Yan Yun Liu MSc 2 | Hertzel C. Gerstein MD 1,2,3 | on behalf of the REMIT-iGlarLixi Collaborative Group

doi : 10.1111/dom.15234

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Development of a novel Fc fusion protein dual glucagon-like peptide-1 and gastric inhibitory polypeptide receptor agonists

Peng Jiang MS 1 | Ningyuan Sun MS 2 | Wen Yang MS 2 | Lin Xiao MS 1 | Linjun Zhou MS 1 | Baohua Gu PhD 2 | Yong Li MS 2 | Lijia Li MS 1 | Jing Li PhD 2 | Xiaoping Li MS 1 | Wenjia Li MS 1 | Linfeng Guo PhD

doi : 10.1111/dom.15235

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The rest-activity rhythm, genetic susceptibility and risk of type 2 diabetes: A prospective study in UK Biobank

Huanyu Wu PhD 1 | Xin Liu PhD 1 | Wenbo Jiang PhD 1,2 | Cong Hu MD 1 | Xuanyang Wang PhD 1 | Zhen Tian PhD 1 | Wenbo Gu PhD 1 | Changhao Sun PhD 1 | Tianshu Han PhD 1 | Wei Wei PhD

doi : 10.1111/dom.15236

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Efficacy of anti-CD3 monoclonal antibodies in delaying the progression of recent-onset type 1 diabetes mellitus: A systematic review, meta-analyses and meta-regression

Muhammad Talal Ashraf MBBS 1 | Syed Hassan Ahmed Rizvi MBBS 1 | Muhammad Arham Bin Kashif MBBS 1 | Muhammad Khuzzaim Shakeel Khan MBBS 1 | Syed Hassan Ahmed MBBS 1 | Muhammad Sohaib Asghar MBBS, MD

doi : 10.1111/dom.15237

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Prevalence of obesity and associated complications in China: A cross-sectional, real-world study in 15.8 million adults

Kang Chen MD 1 | Zewei Shen MMed 2 | Weijun Gu MD 1 | Zhaohui Lyu MD 1 | Xuan Qi MD 3 | Yiming Mu MD 1 | Yi Ning MD 4 | for the Meinian Investigator Group

doi : 10.1111/dom.15238

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A 1-year pilot study of intralymphatic injections of GAD-alum in individuals with latent autoimmune diabetes in adults (LADA) with signs of high immunity: No safety concerns and resemblance to juvenile type 1 diabetes

Ingrid K. Hals PhD 1,2,3 | Chandima Balasuriya MD 2 | Rosaura Casas PhD 4 | Johnny Ludvigsson MD 4,5 | Anneli Bj?rklund MD 6,7 | Valdemar Grill MD

doi : 10.1111/dom.15239

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Effect of sotagliflozin on albuminuria in patients with type 2 diabetes and chronic kidney disease

David Z. I. Cherney MD 1 | Deepak L. Bhatt MD 2 | Michael Szarek PhD 3 | Franklin Sun MS 4 | Manon Girard MS 4 | Michael J. Davies PhD 4 | Bertram Pitt MD 5 | Ph. Gabriel Steg MD 6 | for the SCORED Investigators

doi : 10.1111/dom.15203

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Glycated haemoglobin in the first year after diagnosis of type 1 diabetes is an independent risk factor for diabetic retinopathy: The IMDIAB 25 years follow-up study

Ernesto Maddaloni MD 1 | Angela Carlone 1 | Dario Pitocco 2 | Giulia Leanza 3 | Concetta Suraci MD 4 | Maria Altomare MSc 4 | Maria G. Cavallo MD 1 | Ilaria Barchetta MD 1 | Susanna Morano MD 1 | Chiara Moretti MD 1 | Lucia Coraggio MD 1 | Natalia Visalli MD 5 | Flavia Tramontana PhD 3 | Riccardo Schiaffini MD 6 | Antonino Crin? MD 6 | Raffaella Buzzetti MD 1 | Paolo Pozzilli MD 3 | for the IMDIAB study group

doi : 10.1111/dom.15213

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Baseline leptin predicts response to metformin in adolescents with type 1 diabetes and increased body mass index

Heba M. Ismail MB BCh 1 | Souptik Barua PhD 2,3 | Johnny Wang BS 4 | Ashutosh Sabharwal MS 3 | Ingrid Libman MD 5 | Fida Bacha MD 6 | Kristen J. Nadeau MD 7 | Mustafa Tosur MD 6,8 | Maria J. Redondo MD

doi : 10.1111/dom.15218

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Impact of the COVID-19 pandemic on new diagnoses of type 2 diabetes in England

Emma Barron MSc 1 | Kamlesh Khunti FMedSci 2 | Alison K. Wright PhD 3 | Darren M. Ashcroft PhD 3,4,5 | Matthew J. Carr PhD 3,4,5 | Martin K. Rutter MD 5,6,7 | Jonathan Valabhji MD

doi : 10.1111/dom.15223

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Correction to “Patient perspectives and experiences with basal insulin titration in type 2 diabetes in the United States: A cross-sectional survey�

doi : 10.1111/dom.15253

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