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Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19
Robert L. Gottlieb, MD, PhD1; Ajay Nirula, MD, PhD2; Peter Chen, MD3; Joseph Boscia, MD4; Barry Heller, MD5; Jason Morris, MD, MS6; Gregory Huhn, MD, MPHTM7; Jose Cardona, MD8; Bharat Mocherla, MD9; Valentina Stosor, MD10; Imad Shawa, MD11; Princy Kumar, MD12; Andrew C. Adams, PhD2; Jacob Van Naarden, BS2; Kenneth L. Custer, PhD2; Michael Durante, MS2; Gerard Oakley, MD2; Andrew E. Schade, MD, PhD2; Timothy R. Holzer, PhD2; Philip J. Ebert, PhD2; Richard E. Higgs, PhD2; Nicole L. Kallewaard, PhD2; Janelle Sabo, PharmD2; Dipak R. Patel, MD, PhD2; Paul Klekotka, MD, PhD2; Lei Shen, PhD2; Daniel M. Skovronsky, MD, PhD2
doi : 10.1001/jama.2021.0202
JAMA. 2021;325(7):632-644
Coronavirus disease 2019 (COVID-19) continues to spread rapidly worldwide. Neutralizing antibodies are a potential treatment for COVID-19.
Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee Osteoarthritis
Stephen P. Messier, PhD1,2; Shannon L. Mihalko, PhD3; Daniel P. Beavers, PhD4; Barbara J. Nicklas, PhD2,3; Paul DeVita, PhD5; J. Jeffery Carr, MD6; David J. Hunter, MBBS, PhD7; Mary Lyles, MD2; Ali Guermazi, MD, PhD8; Kim L. Bennell, PT, PhD9; Richard F. Loeser, MD10
doi : 10.1001/jama.2021.0411
JAMA. 2021;325(7):646-657
Thigh muscle weakness is associated with knee discomfort and osteoarthritis disease progression. Little is known about the efficacy of high-intensity strength training in patients with knee osteoarthritis or whether it may worsen knee symptoms.
Associations of Maternal Cardiovascular Health in Pregnancy With Offspring Cardiovascular Health in Early Adolescence
Amanda M. Perak, MD, MS1,2; Nicola Lancki, MPH1; Alan Kuang, MS1; Darwin R. Labarthe, MD, MPH, PhD1; Norrina B. Allen, PhD, MPH1; Svati H. Shah, MD, MHS3; Lynn P. Lowe, PhD1; William A. Grobman, MD, MBA1; Jean M. Lawrence, ScD, MPH, MSSA4,5; Donald M. Lloyd-Jones, MD, ScM1; William L. Lowe Jr, MD1; Denise M. Scholtens, PhD1; for the HAPO Follow-Up Study Cooperative Research Group
doi : 10.1001/jama.2021.0247
JAMA. 2021;325(7):658-668
Pregnancy may be a key window to optimize cardiovascular health (CVH) for the mother and influence lifelong CVH for her child.
Changes in Abortion in Texas Following an Executive Order Ban During the Coronavirus Pandemic
Kari White, PhD, MPH1; Bhavik Kumar, MD, MPH2; Vinita Goyal, MD, MPH3; Robin Wallace, MD, MAS4; Sarah C. M. Roberts, DrPH5; Daniel Grossman, MD5
doi : 10.1001/jama.2020.24096
JAMA. 2021;325(7):691-693
A Blueprint for Comprehensive Medicaid Reform
Rebekah E. Gee, MD, MPH1; David Shulkin, MD2; Iyah Romm, BS3
doi : 10.1001/jama.2021.0013
JAMA. 2021;325(7):619-620
Declining Life Expectancy in the United States
Atheendar S. Venkataramani, MD, PhD1,2; Rourke O’Brien, PhD3,4; Alexander C. Tsai, MD, PhD5,6
doi : 10.1001/jama.2020.26339
JAMA. 2021;325(7):621-622
Recalibrating the Use of Race in Medical Research
John P. A. Ioannidis, MD, DSc1,2; Neil R. Powe, MD, MPH, MBA3; Clyde Yancy, MD, MSc4
doi : 10.1001/jama.2021.0003
JAMA. 2021;325(7):623-624
Race and Pharmacogenomics—Personalized Medicine or Misguided Practice?
Christopher W. Goodman, MD1; Allan S. Brett, MD1
doi : 10.1001/jama.2020.25473
JAMA. 2021;325(7):625-626
Addressing Systemic Racism Through Clinical Preventive Service Recommendations From the US Preventive Services Task Force
Chyke A. Doubeni, MD, MPH1; Melissa Simon, MD2; Alex H. Krist, MD, MPH3
doi : 10.1001/jama.2020.26188
JAMA. 2021;325(7):627-628
Maternal Cardiovascular Health
Stephen R. Daniels, MD, PhD1
doi : 10.1001/jama.2021.0134
JAMA. 2021;325(7):630-631
Diagnosis and Treatment of Metastatic Colorectal Cancer
Leah H. Biller, MD1,2; Deborah Schrag, MD, MPH1,2,3,4
doi : 10.1001/jama.2021.0106
JAMA. 2021;325(7):669-685
Colorectal cancer (CRC) is the third most common cause of cancer mortality worldwide with more than 1.85 million cases and 850?000 deaths annually. Of new colorectal cancer diagnoses, 20% of patients have metastatic disease at presentation and another 25% who present with localized disease will later develop metastases.
Immortal Time Bias in Observational Studies
Kabir Yadav, MDCM, MS, MSHS1,2,3; Roger J. Lewis, MD, PhD1,2,3,4
doi : 10.1001/jama.2020.9151
JAMA. 2021;325(7):686-687
Diagnosis and Treatment of Anal Fissures in 2021
Yang Lu, MD1; Mary R. Kwaan, MD, MPH2; Anne Y. Lin, MD, MSHS2
doi : 10.1001/jama.2020.16705
JAMA. 2021;325(7):688-689
Neutralizing Monoclonal Antibody for Mild to Moderate COVID-19
Preeti N. Malani, MD, MSJ1,2; Robert M. Golub, MD3
doi : 10.1001/jama.2021.0585
JAMA. 2021;325(7):644-645
Hospital Clowns Ease Children’s Symptoms, Review Shows
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2020.26433
JAMA. 2021;325(7):610-611
Advice for n-of-1 Drug Developers
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2021.0921
JAMA. 2021;325(7):613
Generic Glucagon Approved for Severe Hypoglycemia
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2021.0383
JAMA. 2021;325(7):613
More Scrutiny for Laparoscopic Power Morcellator Procedures
Mary Chris Jaklevic, MSJ
doi : 10.1001/jama.2021.0923
JAMA. 2021;325(7):613
High-Income Countries Have Secured the Bulk of COVID-19 Vaccines
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.0189
JAMA. 2021;325(7):612
Clinical Trials Overlook Diseases of Low-Income Countries
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.0842
JAMA. 2021;325(7):612
Global Partnership Aims to Improve Infant HIV Care
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.0844
JAMA. 2021;325(7):612
Lateral Internal Sphincterotomy
Yang Lu, MD1; Anne Lin, MD, MSHS2
doi : 10.1001/jama.2020.16708
JAMA. 2021;325(7):702
Wound Dressings for Obese Women After Cesarean Delivery
Uyen G. Vo, MBBS1; Toby Richards, MD2
doi : 10.1001/jama.2020.24195
JAMA. 2021;325(7):693
Wound Dressings for Obese Women After Cesarean Delivery—Reply
Methodius G. Tuuli, MD, MPH1; Lorie Harper, MD, MSCI2
doi : 10.1001/jama.2020.24198
JAMA. 2021;325(7):693
The Advantages of Medicare Advantage
Samuel Metz, MD1
doi : 10.1001/jama.2020.24281
JAMA. 2021;325(7):693-694
The Advantages of Medicare Advantage—Reply
Stuart M. Butler, PhD1
doi : 10.1001/jama.2020.24284
JAMA. 2021;325(7):694
Geographic Differences in Uncontrolled Chronic Medical Conditions
Erin L. Tompkins, MD, MPH1; Joseph M. Maciuba, MD1; Mary A. Andrews, MD, MPH1
doi : 10.1001/jama.2020.24598
JAMA. 2021;325(7):694
Geographic Differences in Uncontrolled Chronic Medical Conditions—Reply
Aaron Baum, PhD1; Albert L. Siu, MD, MSPH2; Mark D. Schwartz, MD3
doi : 10.1001/jama.2020.24604
JAMA. 2021;325(7):694-695
Database Updates and Resulting Changes in Data in Study of Vaginal Mesh Hysteropexy vs Vaginal Hysterectomy
Charles W. Nager, MD1
doi : 10.1001/jama.2021.0477
JAMA. 2021;325(7):695-696
